M. PATTISON, R. R. FRASER, G. J. O'NEILL, AND J. F. K. WILSHIRE. Received May 1, 1966. Members of the series of a-fluorocarboxylic acid chlorides, ...
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Amides and Benzenoids from
(10-12) While many of these boron-mediated processes are promising, to date the ... followed by distillation, gave the borate ester in 33â48% yield on 25â50 g scale, ... The reaction time could be reduced from 15 to 5 h with only a small decrease
Dec 7, 2011 - Amines 1 and Acids 4. â Bristol-Myers Squibb Company, Princeton, New Jersey. â¡ Bristol-Myers Squibb Company, Pennington, New Jersey.
Dec 7, 2011 - Amide Formation in One Pot from Carboxylic Acids and Amines via Carboxyl and Sulfinyl Mixed Anhydrides. Bartosz K. ZambroÅ ... Acid-Promoted Chemoselective Introduction of Amide Functionality onto Aromatic Compounds Mediated by an Isoc
Jan 3, 2014 - (1) Most methods rely upon nucleophilic addition of the free amines onto an activated acyl ... Using a 0.1 M solution of 3A and 5aa in MeCN a slow reaction was observed at 70 °C ... 4-Me2N-C6H4CO2H, 3N, 4aN, 48, 0. ..... 1999, 121, 268
Dec 7, 2011 - Bristol-Myers Squibb Company, Research and Development, P.O. Box .... Seung-Yong Seo , Yeon-Ju Lee , Hyi-Seung Lee , Heesoon Lee , Jin ...
Dec 7, 2011 - Amide formation from acids and amines is one of the most fundamental reactions in organic synthesis. It plays a key role in peptide synthesis and medicinal chemistry. The general strategy for amide bond formation is the activation of ca
Dec 7, 2011 - In the presence of AlMe3, amines can be directly coupled with acids through dimethylaluminum amide intermediates to form the corresponding ...
