Chapter 11
Fluorous Nanoflow Microreactor: Nanoflow Microreactor with Fluorous Lanthanide Catalysts for Increase in Reactivity and Selectivity Downloaded by UNIV OF LIVERPOOL on December 14, 2015 | http://pubs.acs.org Publication Date: January 11, 2007 | doi: 10.1021/bk-2007-0949.ch011
Koichi Mikami and Takayuki Tonoi Department of Applied Chemistry, Tokyo Institute of Technology, Meguro-ku, Tokyo 152-8552, Japan
The regioselectivity and reaction rate of the fluorous lanthanide complex-catalyzed Mukaiyama aldol and BaeyerVilliger reactions were significantly increased using our nanoflow microreactor. A moderate level of kinetic resolution was also observed even in the lowest concentration of the fluorous lanthanide catalysts (catalyst-to-substrate (C/S) molar ratio is less than 1:1000(
