Anal. Chem. 1985,57,1969-1974
the analyte has not completely escaped the sample and contributed to the signal in the early portion of the regression interval. For example, at 0.2 s in Figure 8 considerably more analyte is detected in (a) than (b), yet at 0.5 s the two are nearly identical. The net effect is to reduce the slope of the extrapolation line in (b) and thereby reduce the concentration determined. Of interest though is the relative insensitivity of the error and the large region in parameter space where accurate (error
