Functional Modification of Electrospun Poly(ε-caprolactone) Vascular

Mar 9, 2017 - ...
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Functional Modification of Electrospun Poly(ε-caprolactone) Vascular Grafts with the Fusion Protein VEGF−HGFI Enhanced Vascular Regeneration Kai Wang,†,# Qiuying Zhang,†,# Liqiang Zhao,‡ Yiwa Pan,† Ting Wang,§ Dengke Zhi,† Shaoyang Ma,† Peixin Zhang,† Tiechan Zhao,∥ Siming Zhang,∥ Wen Li,† Meifeng Zhu,† Yan Zhu,∥ Jun Zhang,*,† Mingqiang Qiao,*,‡ and Deling Kong*,† †

Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China § Urban Transport Emission Control Research Centre, College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China ∥ Center for Research and Development of Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China ‡

S Supporting Information *

ABSTRACT: Synthetic artificial vascular grafts have exhibited low patency rate and severe neointimal hyperplasia in replacing small-caliber arteries (