Gilford Instrument Laboratories, Inc. - Analytical Chemistry (ACS

May 25, 2012 - Chem. , 1981, 53 (8), pp 984A–984A. DOI: 10.1021/ac00231a771. Publication Date: July 1981. Copyright © 1981 American Chemical Societ...
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BIOTECHNOLOGY Gilford Has

Had Designs On It For Years· And the Latest Design Is S y s t e m 2 6 0 0 Biotechnology may require many sophisticated, photometric techniques, but t h e good news is that you can perform them all with one instrument...Gilford's microprocessorcontrolled System 2600. It offers new computerdirected "twists" on traditional Gilford strengths in kinetics, DMA, thermal denaturation, gel scanning, column monitoring, and so on...in short, all those techniques so vital to the biotechnology labora­ tory. The graphs tell the story, clearly:

D e o x y r i b o n u c l e a s e (beef spleen) hydrolysis of DNA. System 2600 measures absorbance vs time, monitoring a low-rate kinetic reaction at 260nm. On the printer tape, the measurement of the 1st derivative vs time provides the final rate analysis in Δ/4/minute.

D λ p h a g e DNA d e n a t u r a t i o n . using the 1st derivative overlay, System 2600 (fitted with the Gilford Thermoprogrammer) examines the fine struc­ ture of the melting profile...several thermalites, the subtransitions within the normal sigmoidal profile. Bear in mind that System 2600 collects (and stores) the melt data and then presents it again as the 1st derivative overlay. Take a minute t o look over t h e graphs. Take t h e n e x t minute t o c o n t a c t u s for more information about S y s t e m 2 6 0 0 and i t s biotechnology-oriented accessories. Those could b e t h e m o s t useful t w o m i n u t e s you've s p e n t all year. Gilford Instrument Laboratories, Inc., 132 Artino Street, Oberlin, OH 44074. (800) 321-3881. toll free, or (216) 774-1041.

Gilford Research Systems for the '80s: Every Job Easier, Every Result More Accurate. ECO RI d i g e s t of λ p h a g e DNA. Polyacrylamide tube gel electrophoresis clearly reveals the fragments of DMA. using the 20cm Gel Scanner, System 2600 identifies the distance migrated and integrates the area under the peaks.

gilford A Subsidiary of Corning Glass Works

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