Gold Nanocages: Bioconjugation and Their

and chloroauric acid.5 Different from previously reported nanostructures (such as Au shells and SiO2@Au core-shell colloids),6 our nanocages could be ...
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Gold Nanocages: Bioconjugation and Their Potential Use as Optical Imaging Contrast Agents

2005 Vol. 5, No. 3 473-477

Jingyi Chen,†,+ Fusayo Saeki,‡,+ Benjamin J. Wiley,§ Hu Cang,†,‡ Michael J. Cobb,‡ Zhi-Yuan Li,| Leslie Au,† Hui Zhang,⊥ Michael B. Kimmey,# Xingde Li,*,‡ and Younan Xia*,† Department of Chemistry, Department of Bioengineering, Department of Chemical Engineering, DiVision of Gastroenterology, Department of Medicine, UniVersity of Washington, Seattle, Washington 98195, Institute of Physics, Chinese Academy of Sciences, Beijing 10080, China, and Institute for Systems Biology, Seattle, Washington 98103 Received December 10, 2004; Revised Manuscript Received January 26, 2005

ABSTRACT Gold nanocages of