Gram-Scale Synthesis of (+)-Discodermolide - Organic Letters (ACS

ORGANIC LETTERS

Additions and Corrections Vol. 1, 1999

Amos B. Smith III,* Michael D. Kaufman, Thomas J. Beachamp, Matthew J. LaMarche, and Hirokazu Arimoto Gram-Scale Synthesis of (+)-Discodermolide. Pages 1823 and 1824. In the abstract and Scheme 1, (-)-C should be drawn as shown below:

OL006090U 10.1021/ol006090u Published on Web 06/22/2000

Hassen Ratni and E. Peter Ku1 ndig* Synthesis of (-)-Lasubine(I) via a Planar Chiral (η6Arene)Cr(CO)3] Complex. Page 1998, Scheme 1. The correct configuration of the aminal in 4a and 5a is (S,S). Scheme 1. Preparation of [(+)-4,5Dimethoxy-2-(trimethylsilyl)benzaldehyde)Cr(CO)3] (3a)

a (i) HC(COMe) , MeOH, pTsOH, MS 4 Å, 98%; (ii) Cr(CO) , nBu O, 3 6 2 THF, 140 °C, 80%; (iii) HCl, THF, 98%; b(i) L-valinol, Et2O, MS 4 Å; (ii) c column chromatography, then HCl, THF then HCl, THF, ee > 99%; (S,S)1,2-bis(N-methylamino)cyclohexane, MS 4 Å, Et2O, 95%; dCr(CO)6, nBu2O, THF, 140 °C, 35%, de 84%; e(i) column chromatography, then HCl, THF, 95%, ee >99%.

OL006092E 10.1021/ol006092e Published on Web 06/08/2000

2000 Vol. 2, No. 13 1983-1984

ORGANIC LETTERS Vol. 2, 2000

Kevin W. Hunt and Paul A. Grieco* Baeyer-Villiger Oxidation Promoted by Reaction of Peracids with Cyclic Oxocarbenium Ions Generated in Situ from Internal Hemiketals. Page 1717. Structures 3 and 4 appeared lacking the X and a methyl group. Structures 3 and 4 should appear as shown:

OL000143Q 10.1021/ol000143q Published on Web 06/22/2000

2000 Vol. 2, No. 13 1984