4A
Β I Ο C Η E Μ ΙS T RY
EDITOR
HANS NEURATH, University of Washington
Charles R. Bertsch, Senior Production Editor
ASSISTANT EDITORS
Milton P. Gordon, University of Washington AMERICAN CHEMICAL SOCIETY PUBLICATIONS
Edmond H. Fischer, University of Washington
1155 Sixteenth Street, N.W., Washington, D. C. 20036
BOARD O F ASSOCIATE EDITORS
Joseph H. Kuney, Director of Business Operations Director of Publications Research
Richard L. Kenyon, Director of Publications
David E. Gushee, Publication Manager, Journals
Eric G. Ball, Harvard Medical School Clinton E. Ballou, University of California, Berkeley Herbert E. Carter, University of Illinois Herman Eisen, Washington University Edmond H. Fischer, University of Washington Heinz Fraenkel-Conrat, University of California, Berkeley Joseph S. Fruton, Yale University David K. Fukushima, Montefiore Hospital, New York Gordon G. Hammes, Cornell University Rollin D. Hotchkiss, Rockefeller Institute Eugene P. Kennedy, Harvard Medical School Henry A. Lardy, University of Wisconsin Fritz A. Lipmann, Rockefeller Institute Alton Meister, Tufts University School of Medicine Marshall W. Nirenberg, National Institutes of Health Howard K. Schachman, University of California, Berkeley Esmond E. Snell, University of California, Berkeley Herbert A. Sober, National Institutes of Health Bert L. Vallee, Harvard Medical School Harland G. Wood, Western Reserve University
SECRETARY OF THE BOARD
Warren E. C. Wacker, Harvard Medical School
© Copyright, 1967, by the American Chemical Society. Published monthly by the American Chemical Society at 20th and Northampton Streets, Easton, Pennsylvania. Second-class postage paid at Easton, Pennsylvania. Manuscripts for publication and correspondence regarding accepted papers should be sent to the Editor, Hans Neurath, University of Washington, Seattle, Washington 98105. Proof, edited manuscripts, and reprint orders should be sent to Research Journals Production Office, American Chemical Society, 20th and Northampton Streets, Easton, Pa. 18042. Senior Produc tion Editor: Charles R. Bertsch. Assistant Senior Production Editor: Marianne C. Brogan. Editorial Assistant: Patricia A. Bronko. Advertising Office: Reinhold Publishing Corporation, 430 Park Avenue, New York, Ν. Υ. 10022. The American Chemical Society and the Editors of Biochem istry assume no responsibility for the statements and opinions advanced by contributors to this journal. Business and Subscription Information Remittances and orders for subscriptions and for single copies, notices of changes of address and new professional connections, and claims for missing numbers should be sent to the Subscrip tion Service Department, American Chemical Society, 1155 Sixteenth Street, N.W., Washington, D. C. 20036. Changes of address for this journal must be received four weeks before the first issue is to go to the new address. Such notification should include both old and new addresses and ZIP code. Please enclose a mailing label from a copy of one of your ACS publications with your notification. Claims for missing numbers will not be allowed (1) if received more than sixty days from date of issue plus time normally re quired for postal delivery of journal and claim, (2) if loss was due to failure of notice of change in address to be received before the date specified in the preceding paragraph, or (3) if the reason for the claim is "missing from files." Subscription rates for 1967: to members, $16.00 per year; to nonmembers, $32.00 per year. Postage to Canada and coun tries in the Pan-American Union, $1.00; all other countries, $1.50. Single copies: for current year, $3.00. Postage, single copies: to Canada and countries in the Pan-American Union, $0.15 ; all other, $0.20.
