EDITOR
HANS NEURATH, University of Washington
ASSOCIATE EDITORS
Milton P. Gordon, University of Washington Edmond H. Fischer, University of Washington William W. Parson, University of Washington
Published by the AMERICAN CHEMICAL SOCIETY
1155 16th Street, N.W. Washington. D. C. 20036 BOOKS AND JOURNALS DIVISION
John Κ Crum Director Ruth Reynard Assistant to the Director Charles R. Bertsch Head, Editorial Processing Department D. H. Michael Bowen Head, Journals Department Bacil Guiley Head, Graphics and Production Department Seldon W. Terrant Head, Research and Development Department
EDITORIAL ADVISORY BOARD
Konrad Bloch, Harvard University Paul D. Boyer, University of California, Los Angeles Ludwig Brand, Johns Hopkins University W. Wallace Cleland, University of Wisconsin Roger D. Cole, University of California, Berkeley Minor J. Coon, University of Michigan Medical School Jack Gorski, University of Illinois Irwin C. Gunsalus, University of Illinois Lowell P. Hager, University of Illinois William F. Harrington, Johns Hopkins University William P. Jencks, Brandeis University Irving M. Klotz, Northwestern University Daniel E. Koshland, University of California, Berkeley Marian E. Koshland University of California, Berkeley Edwin G. Krebs, University of California, Davis Michael Laskowski, Jr., Purdue University Albert L. Lehninger, Johns Hopkins University Nelson J. Leonard, University of Illinois Albert S. Mildvan, Institute for Cancer Research, Philadelphia Kivie Moldave, University of California, Irvine Mary Jane Osborne, University of Connecticut William D. Phillips, Du Pont Experimental Station Joanne Ravel, University of Texas Phillips W. Robbins, Massachusetts Institute of Technology Irwin A. Rose, Institute for Cancer Research, Philadelphia Harold A. Scheraga, Cornell University S. Jonathan Singer, University of California, San Diego Earl R. Stadtman, National Heart Institute Charles C. Sweeley, Michigan State University Ignacio Tinoco, Jr., University of California, Berkeley Paul O. P. Ts'o, Johns Hopkins University Κ. Ε. Van Holde, Oregon State University
SECRETARY OF THE BOARD
Warren E. C. Wacker, Harvard Medical School
4A
BIOCHEMISTRY,
V O L . 1 2 , NO. 8, 1 9 7 3
© Copyright, 1973, by the American Chemical Society. Published biweekly by the American Chemical Society at 20th and Northampton Streets, Easton, Pennsylvania. Second-class postage paid at Washington, D. C , and at additional mailing offices. Manuscripts for publication and correspondence regarding accepted papers should be sent to the Editor, Hans Neurath, University of Washington, Seattle, Washington 98105. Proof, edited manuscripts, and reprint orders should be sent to Editorial Processing Department, American Chemical Society, 20th and Northampton Streets, Easton, Pa. 18042. Head, Charles R. Bertsch. Senior Production Editor: Mari anne C. Brogan. Assistant Editors : Patricia A. Bronko and Deborah A. Wilson. Advertising Office: Centcom, Ltd., 142 East Avenue, Norwalk, Con necticut 06851. The American Chemical Society and the Editors of Biochemistry assume no responsibility for the statements and opinions advanced by contributors to this joural. Business and Subscription Information Remittances and orders for subscriptions and for single copies, no tices of changes of address and new professional connections, and claims for missing numbers should be sent to the Subscription Service Department, American Chemical Society, 1155 Sixteenth Street, N. W., Washington, D. C. 20036. Changes of address for this journal must be received four weeks before the first issue is to go to the new address. Such notification should include both old and new addresses and ZIP code. Please enclose a mailing label from a copy of one of your ACS publications with your notification. Claims for missing numbers will not be allowed (1) if received more than sixty days from date of issue plus time normally required for pos tal delivery of journal and claim, (2) if loss was due to failure of notice of change in address to be received before the date specified in the pre ceding paragraph, or (3) if the reason for the claim is "missing from files." Subscription rates for 1973: to members, $20.00 per year; to non members, $60.00 per year. Those interested in becoming members should write to the Admissions Department, American Chemical So ciety, 1155 Sixteenth St., N.W., Washington, D. C. 20036. Postage to Canada and countries in the Pan-American Union, $5.00; all other coun tries, $6.00. Single copies: for current year, $3.00. Rates for back issues and volumes are available from Special Issues Sales Department, 1155 Sixteenth St., N.W., Washington, D. C. 20036. This publication and the other ACS periodical publications are now available on microfilm. For information write to: MICROFILM, Special Issues Sales Department, American Chemical Society, 1155 Sixteenth St., N.W., Washington, D. C. 20036.
