EDITOR
HANS NEURATH, University of Washington
Published by the AMERICAN CHEMICAL SOCIETY
1155 16th Street, N.W. Washington, D. C. 20036 ASSOCIATE EDITORS
Milton P. Gordon, University of Washington Edmond H. Fischer, University of Washington William W. Parson, University of Washington
E D I T O R I A L ADVISORY B O A R D
Robert H . Abeles, Brandeis University Paul D. Boyer, University of California, Los Angeles Ludwig Brand, Johns Hopkins University W. Wallace Cleland, University of Wisconsin Roger D. Cole, University of California, Berkeley Carl Frieden, School of Medicine, Washington University Jack Gorski, University of Illinois Irwin C. Gunsalus, University of Illinois Lowell P. Hager, University of Illinois William F. Harrington, Johns Hopkins University Leroy Ε. Hood, California Institute of Technology F. M. Huennekens, Scripps Clinic & Research Foundation Irving M. Klotz, Northwestern University Daniel E. Koshland, University of California, Berkeley Marian E. Koshland, University of California, Berkeley Edwin G. Krebs, University of California, Davis Henry A. Lardy, University of Wisconsin Michael Laskowski, Jr., Purdue University Phil Leder, National Institutes of Health William J. Lennarz, Johns Hopkins University Nelson J. Leonard, University of Illinois Harden M. McConnell, Stanford University Albert S. Mildvan, Institute for Cancer Research, Philadelphia Kivie Moldave, University of California, Irvine Mary Jane Osborne, University of Connecticut Joanne Ravel, University of Texas Phillips W. Robbins, Massachusetts Institute of Technology Irwin A. Rose, Institute for Cancer Research, Philadelphia Howard K. Schachman, University of California, Berkeley Elliott Shaw, Brookhaven National Laboratories S. Jonathan Singer, University of California, San Diego Earl R. Stadtman, National Heart Institute Ignacio Tinoco, Jr., University of California, Berkeley Bert L. Vallee, Harvard University Κ. Ε. Van Holde, Oregon State University Finn Wold, University of Minnesota S E C R E T A R Y O F T H E BOARD
Warren E. C. Wacker, Harvard Medical School
BOOKS AND JOURNALS DIVISION
John Κ Crum Director Ruth Reynard Virginia E. Stewart Assistants to the Director
Charles R. Bertsch Head, Editorial Processing Department D. H. Michael Bowen Head, Journals Department Bacil Guiley Head, Graphics and Production Department Seldon W. Terrant Head, Research and Development Department © Copyright, 1975, by the American Chemical Society. Published biweekly by the American Chemical Society at 20th and Northampton Streets, Easton, Pennsylvania. Second-class postage paid at Washington, D.C., and at additional mailing offices. Manuscripts for publication and correspondence regarding accepted papers should be sent to the Editor, Hans Neurath, University of Washington, Seattle, Washington 98195. Proof, edited manuscripts, and reprint orders should be sent to Editorial Processing Department, American Chemical Society, 20th and Northampton Streets, Easton, Pa. 18042. Department Head: Charles R. Bertsch. Assistant Depart ment Head: Marianne C. Brogan. Assistant Editor: Deborah A. Wil son. Editorial Assistant: Holley A. Stewart. Advertising Office: Centcom, Ltd., 50 W. State St., Westport, Con necticut 06880. The American Chemical Society and the Editors of Biochemistry as sume no responsibility for the statements and opinions advanced by contributors to this journal. Business and Subscription Information Send all new and renewal subscriptions with payment to: Office of the Controller, 1155 16th Street, N.W., Washington, D.C. 20036. Sub scriptions should be renewed promptly to avoid a break in your series. All correspondence and telephone calls regarding changes of address, claims for missing issues, subscription service, the status of records, and accounts should be directed to: Manager, Membership and Sub scription Services, American Chemical Society, P.O. Box 3337, Co lumbus, Ohio 43210. Telephone (614) 421-7230. For microfiche ser vice, contact ACS Journals Department, 1155 16th St., N.W., Wash ington, D.C. 20036. Telephone (202) 872-4444. On changes of address, include both old and new addresses with ZIP code numbers, accompanied by mailing label from a recent issue. Allow four weeks for change to become effective. Claims for missing numbers will not be allowed ( 1 ) if loss was due to failure of notice of change in address to be received before the date above, (2) if received more than sixty days from date of issue plus time normally required for postal delivery of journal and claim, or (3) if the reason for the claim is "issue missing from files." Subscription rates (hard copy or microfiche) in 1975: $20.00 to ACS members, $80.00 to nonmembers. Extra postage $7.00 in Canada and PUAS, $8.00 other foreign. Microfiche is airmailed to non-U.S. ad dresses; air freight rates for hard-copy subscriptions available on re quest. Single copies: for current year, $4.00. Rates for back issues and vol umes are available from Special Issues Sales Department, 1155 Six teenth St., N.W., Washington, D.C. 20036. Subscriptions to this and the other ACS periodical publications are available on microfilm. For information on microfilm subscriptions, write Special Issues Sales Department at the address above.
