Trubek's modern plant at East Rutherford, New Jersey includes specialized equipment for the production of acid chlorides, and many other organic compounds.
High purity acid chlorides from The advantages of using Acid Chlorides in certain reactions of organic chemistry are widely known. However, companies using these compounds have often encountered annoying and expensive production problems. Frequently these stem from contaminants in the acid chlorides used. For, in many cases the company requiring organic acid chlorides attempts to produce* these compounds on its own, often using inadequate equipment . . . and without the proper "know-how". By contrast, many of the leading chemical and pharmaceutical companies have come to recognize Trubek as the experienced producer whenever an acid chloride is required. Trubek has assembled and developed specialized equipment and evolved specific techniques to permit it to rapidly and economically fill orders for organic chlorides of the highest quality. Trubek today is widely recognized as "the" dependable and economical source for acid chlorides.
AVAILABLE FROM STOCK Trubek stocks many of the more commonly used acid chlorides and is prepared to fill orders ranging from a few pounds to carload lots. Among those available are: • • • • • • • • •
Acetyl Chloride • Isovaleroyl Chloride Adipoyl Chloride • Lauroyl Chloride Azelaoyl Chloride • Myristoyl Chloride Butyroyl Chloride • Oleoyl Chloride Caproyl Chloride • Palmitoyl Chloride Capryloyl Chloride • Pelargonyl Chloride Cinnamoyl Chloride • Phenylacetyl Chloride Decanoyl Chloride • Propionyl Chloride Isobutyroyl Chloride • Sebacoyl Chloride • Stearoyl Chloride
OR MADE TO ORDER In addition Trubek has often produced special purpose acid chlorides on an individual order basis. Because of 52
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the backlog of specialized knowledge thus made available, and the specialized equipment and experienced personnel at Trubek, you can depend on quick, effective production of almost any organic acid chloride on a made-to-order basis.
TYPICAL REACTIONS Under proper conditions, the chloride atom of these versatile compounds is replaced when they are reacted with: H OR' Alcohols R.CO CI + (Alcoholysis) H NH 2 Ammonia R.CO CI + (Ammonolysis) H NHR' Primary Amines R.CO CI + (Aminolysis) H NR'2 R.CO CI + Secondary Amines (Aminolysis) K OOCR' R.CO CI + Salts of Organic Acids R.CO CI + XMg R' Grignard Reagent Sodium Peroxide R.CO CI + Na2 o 2 H Aromatic Hydrocarbons 2 R.CO CI + (Friedel-Crafts Reaction)
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TYPICAL U S E S Because of their versatility and activity, acid chlorides are used in the production of esters, amides, ketones, peroxides, anhydrides and many other compounds. Typical applications are: • Organic synthesis where mild conditions are required due to vulnerability of compounds to heat and temperature. • As an acylating agent, to introduce the acyl group in reactions with alcohols, amines and other compounds. • Where polmerization-condensation reactions to produce polyamides or polyesters must be conducted under
AtTrubek continuous research develops better analytical techniques...to provide better production control methods which insure product uniformity and quality.
Complete facilities for drum, tank car and tank truck shipments insure fast handling of your order, regardless of size.
Trubek, the experienced producer mild conditions. Here the dibasic acid chlorides such as Sebacoyl Chloride and Adipoyl Chloride are used. • In substitution reactions with salts of organic acids to give anhydrides relatively free from side products. • In the manufacture of organic peroxides. • In the synthesis of surfactants through reactions with secondary amines. • In the preparation of pharmaceutical esters such as the palmitates and stearates where stability, solubility and taste are important factors. • In the manufacture of aromatic ketones through the Friedel-Crafts reaction.
CUSTOM PROCESSING O F ORGANIC C O M P O U N D S Trubek often assumes responsibility for the production of new chemical compounds or products developed by other leading chemical or pharmaceutical companies. This enables the companies who become Trubek customers to realize many advantages. I t does away with the necessity to risk c a p i t a l . . . and eliminates the possibility of expensive "white elephant" plants which run at a loss when projected requirements fail to materialize. In many cases, Trubek custom processing provides particular advantages for a customer who is in a rush to get into production . . . enables him to go from a laboratory sample to large volume in an absolute minimum of time.
H I G H E R PURITY C O M P O U N D S The high purity of Trubek's Acid Chlorides is assured by specialized equipment, experience and "know how" • • • reinforced by rigorous quality control based on highly refined analytical techniques, including the latest chromatographic and spectroscopic methods.
OTHER ORGAN1CS AVAILABLE In addition to Acid Chlorides, Trubek supplies from stock a wide spectrum of organic compounds including organic intermediates, benzyl chloride derivatives and aroma and flavor chemicals from both natural and synthetic sources. If you are looking for an unusual organic compound, it may be available as a stock item from Trubek.
IT PAYS
CALL OR WRITE If you're interested in a pound or carload delivery of one of the acid chlorides listed . . . wonder about the feasibility of producing still another acid chloride . . . have some questions on organic acid chloride chemistry . . . or wonder about the possible advantages in having Trubek produce other organic compounds . . . we'd like to hear from you. So write today. Or better yet, for really fast action give us a call. Our telephone number is (Area Code 201) GEneva 8-7800.
TO TALK TO THE TRUBEK LABORATORIES
East Rutherford, New Jersey A DIVISION O F U N I V E R S A L OIL PRODUCTS COMPANY C & E N 53
