Anal. Chem. 2009, 81, 7096–7101
High-Throughput Mode Liquid Microjunction Surface Sampling Probe Gary J. Van Berkel* and Vilmos Kertesz Organic and Biological Mass Spectrometry Group, Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6131 Richard C. King PharmaCadence, 2880 Bergey Road, Suite AA, Hatfield, Pennsylvania 19440 A simple and automated spot sampling operation mode for a liquid microjunction surface sampling probe/electrospray ionization mass spectrometry (LMJ-SSP/ESI-MS) system is reported. Prior manual and automated spot sampling methods with this probe relied on a careful, relatively slow alignment of the probe and surface distance (
