Highly Efficient and Reusable Supported Pd Catalysts for Suzuki

ORGANIC LETTERS

Highly Efficient and Reusable Supported Pd Catalysts for Suzuki−Miyaura Reactions of Aryl Chlorides†

2007 Vol. 9, No. 19 3777-3780

Ste´phane Schweizer, Jean-Michel Becht,* and Claude Le Drian* UniVersite´ de Haute-Alsace, Ecole Nationale Supe´ rieure de Chimie de Mulhouse Laboratoire de Chimie Organique et Bioorganique, UMR-CNRS 7015, 3 rue Alfred Werner, 68093 Mulhouse cedex, France [email protected] Received June 20, 2007

ABSTRACT

Syntheses of air- and moisture-stable heterogeneous (tert-butylarylphosphino)polystyrene-supported Pd catalysts and their use for versatile Suzuki−Miyaura reactions of aryl chlorides and arylboronic acids under non-anhydrous conditions are reported. The catalysts are easily recovered by filtration. They can be used many times (more than seven) without showing any loss of activity, and the amount of Pd leached is extremely low (