Hit and Run - C&EN Global Enterprise (ACS Publications)

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Hit and Run

Hit-fa-lead optimization, Natyral core libraries.. Hit-to-lead optimization. It is the one of the most critical stages in drug discovery. A stage where most bottlenecks occur and where an estimated 70% of hits are lost. A stage where utilizing Aurigene's drug discovery support services makes the most sense. Aurigene reduces the time and cost of drug discovery while increasing the probability of success in its early stages. Aurigene does this by solving novel protein and co-crystal structures, identifying the critical structural features of hits, and rapidly optimizing leads using intelligent screening and the most advanced quantitative and computational techniques,

USA Corporate Headquarters 99 Hayden Avenue Lexington. Massachusetts 02420 Phone: 1 781 541 6727 Fax: 1 781 541 6742

Aurigene can even provide excellent starting points and back up your existing leads with privileged libraries of proprietary scaffolds and building blocks; unique libraries of drug-like compounds built from natural cores; and focused synthetic libraries based on parallel synthesis according to your specific needs.

INDIA Aurigene Discovery Technologies Limited Electronic City Phase II, Hosur Road Bangalore 562158 Phone: +91 80 852 8943 Fax: +91 80 852 6285

So, if you need a faster way to bridge the gap between target identification and candidate drug, contact Aurigene today. We'll help you hit the ground running. For information, contact Andy Keesler at 908-369-1106, email: [email protected], or visit www.aurigene.com.

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Accelerating Discovery