A NEWSYNTHESIS OF ACETYL DIHYDROGEN PHOSPHATE
June, 1948 [CONTRIBUTION FROM
THE
2183
DEPARTMENT OF BIOCHEMISTRY, COLLEGE OF PHYSICIANS AND SURGEONS, COLUMBIA UNIVERSITY]
A New Synthesis of Acetyl Dihydrogen Phosphate1 BY RONALD BENTLEY~ Acetyl dihydrogen phosphate (I) was first syn- lide. Analogous reactions were observed with thesized by Lynen3 who used the catalytic de- ammonia. benzylation of acetyl diRNHZ in RNHi>pcO Heat in RNHs>pGO benzyl phosphate. Later, ___) Lipmann and ‘I’uttle‘ de- H>pc>COCHs ether RNH, O-COCH, EtOH RNHI H scribed its preparation I1 CH,COOQHb from silver dihydrogen aq. R N H ~ J phosphate and acetyl chloride; in each case the aceRNH3>P
