How AEROSIL speeds tablet disintegration - C&EN Global Enterprise

Nov 7, 2010 - Advertisements that appeared within the print issues of Chem. Eng. News have been included in the C&EN Archives to provide a ...
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How AEROSIL speeds tablet disintegration

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AEROSIL acts like a wick to channel water directly to the starch disintegrator in your tablet and accelerate the disintegration process. The inert, 99.8% pure fumed silica also insulates incompatible ingredients in mixed granulates, with no effect on the active ingredients. The pure-white, highly dispersed silica particles greatly improve the flow of powders for tableting — strongly hygroscopic plant extracts remain loose and free-flowing. AEROSIL is an outstanding auxiliary for turning liquid and paste ingredients into free-flowing powders, for grinding and for sieving.

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Pharmaceuticals + AEROSIL

Pilling time reduced 75 %

Greater accuracy of dosage

Small quantities of AEROSIL in the covering or coating powder, syrup or pigment suspension, accelerate drying of the powders and evaporation of the individual syrup layers. Pilling time is reduced up to 75%. The AEROSIL-enriched coating protects the seeds from ambient moisture. Finer distribution of the covering powder prevents "twin-formation".

When filling gelatin capsules with powders, you can achieve greater accuracy of dosage by adding small quantities of AEROSIL to the powders. AEROSIL also speeds up filling operations. — Both medicated and body powders remain free-flowing — even in high humidity. The AEROSIL particles adhere to the skin and completely adsorb liquids such as secretions or perspiration.

Greater tube output

More than fast disintegration

It's hard to imagine toothpaste without AEROSIL. What better way to impart a smooth texture, stabilize consistency and thicken the paste (greater thixotropy speeds the filling operation). AEROSIL saves up to 5 0 % of your cleansing ingredient and humectant. And because purewhite AEROSIL reduces specific gravity, you get 2 5 % more tube output.

Besides promoting the fast disintegration of tablets, AEROSIL finds versatile applications in the drug industry. As a chemically pure, inert silica, AEROSIL is compatible with any drug ingredient. AEROSIL increases the dispersity of medicinal powders, serves as a grinding and screening aid and stabilizes salves and suppositories.

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DEGUSSA INC 2, PENN. PLAZA, NEW YORK, N.Y. 10001, PHONE: 212-563-7100