books
The 16 chapters cover selecting and running a system, separation models, columns, partition and nonpartition chromatography, hardware, troubleshooting, preparative chromatography, sample preparation, method development, applications, and recent advances in LC/MS. The appendixes provide tables of solvents and volatile buffers, a troubleshooting quick reference, HPLC laboratory experiments, and selected references. A CD is included to help the reader use the models presented in the book.
“a practical summary of what the reader needs to know in order to carry out any gradient separation; a conceptual understanding of how gradient elution works; and a detailed examination of the underlying theoretical framework of gradient elution for application to special situations and to satisfy any lingering doubts of the reader.” The nine chapters cover introduction, fundamentals, method development, equipment, artifacts and troubleshooting, separation of large molecules, preparative separations, applications, and theory and derivations. The six appendixes cover the constant S approximation, estimation of conditions on the basis of an initial run, characterization of reversed-phase columns, solvent properties, theory of preparative separations, and virus chromatography.
Chiral Separation Techniques: A Practical Approach Ganapathy Subramanian, Ed. Wiley Interscience, 2007, 615 pp, $200, www.wiley.com
Columns for Gas Chromatography: Performance and Selection Eugene F. Barry and Robert L. Grob Wiley Interscience, 2007, 300 pp, $100, www.wiley.com
The book is intended to be helpful to pharmaceutical chemists; biochemists; molecular biologists; pharmacologists; and scientists in agrochemicals, food, and biotechnology. The 17 chapters cover macrocyclic glycopeptide chiral phases, polysaccharides in LC and CE, preparative phases, supercritical fluid chromatography, ligand exchange, moving-bed separations, pharmaceutical applications, crown ether stationary phases, separation of amino acids, CE, countercurrent chromatography, molecularly imprinted polymers, biosensors, capillary electrochromatography coupled to MS, micellar electrokinetic chromatography coupled to MS, polarimeter detectors, and drug discovery.
The four chapters cover introductory material, packed-column GC, capillary column GC, and oven temperature control. In the guide to selecting packed columns in appendix A, the authors have provided (courtesy of Supelco) >170 chromatograms with labeled peaks and separation conditions for various classes of compounds. Appendix B lists general principles of column selection. An index that includes compound names is provided.
HPLC: A Practical User’s Guide Marvin C. McMaster Wiley Interscience, 2007, 240 pp, $75, www.wiley.com
High-Performance Gradient Elution: Practical Application of the Linear-Solvent-Strength Model Lloyd R. Snyder and John W. Dolan Wiley Interscience, 2007, 460 pp, $115, www.wiley.com According to the preface, this book’s three goals are to provide the following: 30
Quantitative Proteomics by Mass Spectrometry Salvatore Sechi, Ed. Humana Press, 2007, 220 pp, $100, www. humanapress.com The chapters cover isotope tagging, isotope labeling, protein interaction studies, absolute quantification, proteins and metabolites, cysteinyl peptide enrichment, coding strategy, proteolytic labeling, newborn screening, isotopecoded affinity tags, computational analysis, mammalian organisms, and cellular signaling networks. Mass Spectrometry Data Analysis in Proteomics Rune Matthiesen, Ed. Humana Press, 2007, 320 pp, $120, www. humanapress.com According to the preface, this volume is intended to “support researchers in deciding which programs to use in various tasks related to analysis of MS data in proteomics.” The 18 chapters include monoisotopic single-charge peaks, MALDI, peptide mass fingerprinting, unigene collection generation, the Virtual Expert Mass Spectrometrist and Sequence Analysis Toolbox programs, interpreting spectra, predicting retention time, stable-isotope labeling, difference gel electrophoresis, data exchange and storage, carbohydrates, and free programs available on the Internet.
Applied Thin-Layer Chromatography Elke Hahn-Deinstrop Wiley, 2007, 315 pp, $165, www.wiley.com
Metabolomics: Methods and Protocols Wolfram Weckwerth, Ed. Humana Press, 2007, 290 pp, $125, www. humanapress.com
The chapters cover precoated layers, solvent systems and developing chambers, derivatization, evaluation without and after derivatization, documentation, conforming operations, stress, and special methods. The photograph section contains 35 pages of plates with separations. Photos and illustrations can be found throughout the book; scientific cartoons are provided where space allows.
According to the preface, although GC/MS is suited ideally to metabolomics, it has its limitations; therefore, other complementary techniques are also discussed. The chapters cover GC/ MS, TOF GC/MS, headspace trapping, pattern recognition and biomarker selection, visualization and analysis, CE/MS, LC/MS, ESI MS, metabolic flux ratios, NMR, animal tissues, drug discovery, and isotope labeling.
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© 2008 American Chemical Societ y
