For an international, molecular focus on the toxicological effects of chemical agents
Chemical Research in Toxicology Published bimonthly by the American Chemical Society Editor: Lawrence J. Marnett Department of Biochemistry & CenterforMolecular Toxicology School of Medicine Vanderbilt University Nashville, TN 37232 (615) 343-7328
Associate Editors: Frederick P. Guengerich Vanderbilt University Paul F. Hollenberg Wayne State University
1993 Subscription Information
J i n primary research reports, Chemical Research in Toxicology covers: • Structure elucidation of novel toxic agents;
Chemical Research in Toxicology is published by the American Chemical Society. One volume per year. 1993 Volume 6 1993 ISSN 0893-228X. U.S.
• Chemical and physical studies on chemical agents that provide insight into their mode or mechanism of action; • Experimental and theoretical investigations of the interaction of toxic chemicals with biological macromolecules and other biological targets; • A range of topics which includes toxicity, teratogenicity, mutagenicity, carcinogenicity, neurotoxicity, and immunotoxicity.
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^ ^ u i d e d by an esteemed, international editorial advisory board, Chemical Research in Toxicofogy delivers peer-reviewed articles and invited reviews, communications and perspectives, such as these: • A Metabolically Competent Human Cell Line Expressing Five cDNAs Encoding Procarcinogen-Activating Ençymes: Application to Mutagenicity Testing. C.L. Crespie, F.J. Gonzalez, D.T. Steimel, T.R. Turner, H.V. Gelvoin, B.W. Penman, and R. Langenbach. • Carbamoylation of Peptides and Proteins In Vitro by S-(N-Methylcarbamoyl) glutathione and S-(N-Methylcarbamoyl,) cysteine, Two Electrophilic S-Linked Conjugates of Methyl Isocyanate. P.G. Pearson, J.G. Slatter, M.S. Rashed, D.-H. Han, and T.A. Billie. • Identification of Epoxide- and Quinone-Derived Bromobenzene Adducts to Protein Sulfur Nucleophiles. D.E. Slaughter and R.P. Hanzlik. • Mass Spectrometric Analysis of Tobacco-Specific Nitrosamine-DNA Adducts in Smokers and Nonsmokers. P.G. Foiles, S.A. Akerkar, S.G. Carmella, M. Kagan, G.D. Stoner, J.H. Resau, and S.S. Hecht.
224 A · ANALYTICAL CHEMISTRY, VOL. 65, NO. 4, FEBRUARY 15, 1993