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Instructions for Authors Scope Topical areas of interest include application of chemical and engineering principles in fields such as kinetics, transport phenomena, control theory, modeling, and material science to phenomena in areas such as molecular biology, genetics, biochemistry, cellular biology, physiology, applied microbiology, and food science. Manuscripts concerning the design of related processes, products, or devices are also encouraged. T h r e e copies of t h e manuscript should be submitted to Dr. Jerome S . Schultz, Editor, Biotechnology Progress, University of Pittsburgh, 911 William Pitt Union, Pittsburgh, PA 15260 [(412) 6487956; FAX (412) 624-7145]. Four types of manuscripts are printed in the Journal: Research Papers, Topical Papers, Letters to the Editor, and R & D Notes. There are n o page charges. Types of Manuscripts 1. Research Papers are full-length expositions of extensive and significant experimental or theoretical studies. 2. Topical Papers are minireviews, state-of-the-art reports, or commentaries. Topical papers are peer reviewed. Criteria for acceptance are technical accuracy, importance, and readability. 3. Letters to the Editor may concern previous Journal articles, comment on research trends or new developments in biotechnology, or offer constructive suggestions toward improving the Journal. A letter should not exceed two double-spaced typewritten pages and should be addressed “To the Editor”. 4. R & D Notes are limited to eight double-spaced typewritten pages including figures and tables. Format may vary with the author’s preference, but the typing, equations, figures, tables, notation, and literature citations should conform to those for Papers. Preparation of Manuscripts For general style, consult recent issues of the journal and T h e A C S Style Guide (1986; available from Distribution Office, American Chemical Society, 1155 16th St., Washington, DC 20036). Abstract. Authors’ abstracts are used directly for Chemical Abstracts. The Abstract should be a clear, concise summary-informative rather than descriptivegiving the scope and purpose, methods or procedures, significant new results, and conclusions. Title. Use specific and informative titles; they should be as brief as possible, consistent with the need for defining the subject area covered by the paper and for indexing and retrieval purposes. Authorship. Be consistent in authorship designation. Use first name, second initial, and surname. Give complete mailing address of place where work was conducted. If the current address is different, include it in a footnote on the title page. T h e name of the author t o whom inquiries about the paper should be addressed should be marked with an asterisk. Text. Assume the reader is not a novice in the field. Include only as much history as is needed to provide background for the particular material covered in your paper. Sectionalize the article and insert appropriate headings. Do not use footnotes in the text. Manuscripts should be typed double spaced (one side only) on 22- x
28-cm ( 8 l / 2 X 11-in.) or A4 paper. Each page should be numbered. Type all equations and formulas clearly, and number equations consecutively by use of Arabic numbers. Place superscripts and subscripts accurately. Structural formulas should be submitted as drawings. All symbols used must be clearly defined. If the number of symbols used is small, it is permissible to define these in the text where they first occur. If the number is large, a separate table of notation must be prepared. Roman symbols should be listed in the table first, then Greek. Should any symbols be handwritten, they should be clearly identified in the margins the first time they are used, as should ambiguous typewritten symbols such as 1,1, zero, or the letter 0. S y s t e m of U n i t s s h o u l d follow t h e S y s t b m e International d’Unitbs for all dimensional quantities. Figures. The figures should be carefully designed and prepared. All lettering should be prepared by lettering set or high-quality printer (typing does not reproduce well) and be of a size that can be read after reduction. Label the axes outside the graph proper. Number all illustrations consecutively. Supply typed captions and legends on a separate page. Original drawings (or sharp prints) of graphs and diagrams and glossy prints of photographs should be provided when the manuscript is submitted. Tables. Avoid tables and graphs that involve superfluous duplication of data. Substitute a few typical results for lengthy tables when practical. Number tables in order of mention in the text. Supplementary Material. Occasionally manuscripts include extensive tables, graphs, spectra, mathematical material, or other “supplementary material” that is of value primarily to those readers who need all of the data or all of the detail. Refer to the supplementary material in the text where appropriate and include a paragraph a t the end of the paper indicating the nature of the supplementary material, using the following format: “Supplementary Material Available: Description of material (no. of pages). Ordering information is given on any current masthead page.” Safety. Authors are requested to call special attentionin both their manuscripts and their correspondence with the editors-to safety considerations such as explosive tendencies, special precautionary handling procedures, and toxicity. Literature Cited. References should be listed on a separate sheet in alphabetical order according to author, patentee, or equivalent. (Do not use “Anonymous”.) References should be cited in the text by the last name of the author (both authors when only two; first author et al. when more than two) and year. Use Chemical Abstracts Service Source Index journal abbreviations, and refer to T h e A C S S t y l e Guide (1986) for style. Do not number references. Include the title of journal articles as well as those for books. Typical citations are illustrated below: Woll, J. M.; Hatton, T. A.; Yarmush, M. L. Bioaffinity Separations Using Reversed Micellar Extraction. Biotechnol. Prog. 1989, 5 , 57-62. Griffiths, D. W. In N u t r i t i o n a l a n d Toxicological Significance of E n z y m e Inhibitors in Foods; Friedman, M. F., Ed.; Plenum: New York, 1986; pp 509516.
