Integrated Drug Discovery & Development - C&EN Global Enterprise

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Integrated Drug Discovery & Development Discovery Lead Optimization

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Ricerca's unique integrated drug discovery program cost-effectively weeds out predictable failures and creates higher value optimal drug candidates for development. Give us your hits...and we'll utilize medicinal chemistry coupled with ADMET to provide optimized leads.

Chemical Development • • • • •

JMLedidnal Chemistry

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Medicinal chemistry In vitro ADMET In vivo ADMET Metabolite ID Bioavailability assessment & optimization* • Microbiology

Our Chemical Development Group and pilot plant can make your drug, efficiently and scaleable for Phase I and Phase II testing.

CMC development API preparations and manufacture Process chemistry and scale-up Peptide synthesis and manufacture* Analytical development; Polymorph screening

Drug Development Biology

Our Drug Development Biology Group provides extensive services to assure the quality of material being used is acceptable to government regulations and patient safety. • • • •

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Twice the Power for Developing Drugs"

IND-enabling toxicology and metabolism Carcogenicity and reproductive tox Bioanalytical method development and sample analysis Regulatory support Strategic Alliance Partners

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Ricerca Biosciences

7528 Auburn Road • Concord, OH 44077 Tel: 888-763-4797 • Fax: 440-357-4939 E-mail: [email protected] • www.ricerca.com