Interplay between Hydration Water and

ARTICLE pubs.acs.org/JPCB

Interplay between Hydration Water and Headgroup Dynamics in Lipid Bilayers P. Berntsen,*,† C. Svanberg,‡ and J. Swenson*,† † ‡

Department of Applied Physics, Chalmers University of Technology, SE-412 96 G€oteborg, Sweden Borealis Innovation Center, Industriv€agen, SE-444 86 Stenungsund, Sweden ABSTRACT: In this study, the interplay between water and lipid dynamics has been investigated by broadband dielectric spectroscopy and modulated differential scanning calorimetry (MDSC). The multilamellar lipid bilayer system 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) has been studied over a broad temperature range at three different water contents: about 3, 6, and 9 water molecules per lipid molecule. The results from the dielectric relaxation measurements show that at temperatures