Intramolecular Quaternization as Folding Strategy for the Synthesis of

Apr 13, 2017 - Lyon , C. K.; Prasher , A.; Hanlon , A. M.; Tuten , B. T.; Tooley , C. A.; .... E.; Miller , R. D. A Novel Approach to Functionalized N...
0 downloads 0 Views 3MB Size
Letter pubs.acs.org/macroletters

Intramolecular Quaternization as Folding Strategy for the Synthesis of Catalytically Active Imidazolium-Based Single Chain Nanoparticles Romain Lambert,†,‡ Anne-Laure Wirotius,†,‡ and Daniel Taton*,†,‡ †

Laboratoire de Chimie des Polymères Organiques Université de Bordeaux IPB-ENSCBP, F-33607 Pessac Cedex, France Laboratoire de Chimie des Polymères Organiques Centre National de la Recherche Scientifique, 16 Avenue Pey-Berland, F-33607 Pessac Cedex, France



S Supporting Information *

ABSTRACT: A novel synthetic strategy to single chain nanoparticles (SCNP) based on a previously unexplored intramolecular reaction as a means to autonomously fold a parent copolymer precursor is reported. The latter is a statistical styrenic-type copolymer synthesized by RAFT polymerization and is composed of four different comonomer units, including styrene, grafted poly(ethylene oxide) chains, and antagonist benzimidazol- and chlorobenzyl-based units. The two latter functions are reacted together by a quaternization reaction to spark the folding process, creating imidazolium-based cross-link points. Formation of SCNP with a hydrodynamic diameter