Editorial pubs.acs.org/CR
Introduction: Supramolecular Chemistry upramolecular chemistry, also known as “chemistry beyond the molecule”, focuses on the study of molecular recognition and high-order assemblies formed by noncovalent interactions. In 1987, the Nobel Prize in Chemistry was awarded jointly to Donald J. Cram, Jean-Marie Lehn, and Charles J. Pedersen “for their development and use of molecules with structure-specif ic interactions of high selectivity”. This established supramolecular chemistry as a well-accepted chemical discipline. Because supramolecular systems are made from building blocks that are linked together by noncovalent interactions, they can show stimuli-responsive behavior. What’s more, fascinating chemical architectures, such as rotaxanes, catenanes, and knots, which are difficult to prepare from covalent chemistry, can be easily prepared through templated synthesis. After only approximately 50 years of the discipline, supramolecular chemistry has been widely explored in various areas, including the following: molecular machines, molecular sensors, gas absorption, nanoreactors, chemical catalysis, and drug delivery. Supramolecular chemistry, therefore, is a cross discipline of organic chemistry, physical chemistry, coordination chemistry, polymer chemistry, materials science, biological science, and so on. The research objectives of supramolecular chemistry involve many and varied classes of molecules. Cook and Stang review the construction and development of metallacycles and metallacages via metal−ligand coordination chemistry. Gao discusses nanocarbons, such as nanotubes, graphene, and fullerenes, and their superstructured assemblies. Beer presents molecular hosts containing halogen bonds and shows their special roles in supramolecular applications. Based on the host−guest interactions and self-assembling process, a large fraction of supramolecular architectures are fabricated to perform functions and tasks. For example, Zhang focuses on supramolecular polymers prepared from selfassembly of small molecules. Huang highlights supramolecular amphiphiles based on host−guest molecular recognition motifs. Liu illustrates the construction of chiral supramolecular assemblies. The development of pseudorotaxanes and rotaxanes, two types of threaded molecules, is summarized by Huang. Because of their dynamic properties, supramolecular assemblies often show stimuli-responsiveness, which can be used in various areas. Tung and Yang discuss self-assemblies with efficient energy transfer and their bioapplications. Tian gives insight into photoresponsive host−guest functional systems. Yam talks about light-emitting self-assembled materials based on d8 and d10 transition metals. Nitschke addresses stimuli responsive metal−ligand assemblies. Zhao summarizes biomedical applications of supramolecular systems based on host−guest interactions. One of the new research areas integrating supramolecular chemistry with analytical chemistry is supramolecular analytical chemistry. It mainly focuses on the creation and application of sensors. You and Anslyn review the recent advances in supramolecular analytical chemistry using optical sensing.
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© 2015 American Chemical Society
Meanwhile, chromogenic/fluorogenic ensemble chemosensing systems are discussed by Kim. Yoon summarizes progress based on the development of chemosensors for gases. James discusses glucose sensing, and Gale summarizes supramolecular anion recognition. We are deeply grateful to all the authors for having contributed these wonderful reviews, which provide a comprehensive understanding for the readers of this thematic issue of supramolecular chemistry. We hope that these topics will stimulate further efforts and contributions to this exciting field. We believe that the publication of this thematic issue is helpful to the development of supramolecular chemistry and will inspire chemists to create new branches of creativity within this discipline.
Feihe Huang*
Zhejiang University
Eric V. Anslyn*
The University of Texas at Austin
AUTHOR INFORMATION Corresponding Authors
*E-mail:
[email protected]. *E-mail:
[email protected]. Notes
Views expressed in this editorial are those of the author and not necessarily the views of the ACS. Biographies
Feihe Huang was born in China in 1973. He obtained his degree of Doctor of Philosophy in Chemistry from Virginia Polytechnic Institute and State University (VT) under the guidance of Prof. Harry W. Gibson in March 2005. He then joined Prof. Peter J. Stang’s group at the University of Utah as a postdoctor. He became a Professor of Chemistry at Zhejiang University in December 2005. His current research interests are supramolecular polymers and cycloarene supramolecular chemistry. Awards and honors he has received include Special Issue: 2015 Supramolecular Chemistry Published: August 12, 2015 6999
DOI: 10.1021/acs.chemrev.5b00352 Chem. Rev. 2015, 115, 6999−7000
Chemical Reviews
Editorial
the 2004 Chinese Government Award for Outstanding Self-Financed Students Abroad, the Outstanding Ph.D. Dissertation Award from VT, Humboldt Fellowship for Experienced Researchers from the Humboldt Foundation, Fellow of the Royal Society of Chemistry, Asian Chemical Congress Asian Rising Stars Award, Chinese Chemical Society AkzoNobel Chemical Sciences Award, and Cram Lehn Pedersen Prize in Supramolecular Chemistry. He has published more than 160 supramolecular chemistry papers. His publications have been cited more than 9222 times with an h-index of 52. He has served as a guest editor for Chemical Society Reviews, Accounts of Chemical Research, Chemical Reviews, and Chemical Communications. He sits on the Advisory Boards of Chemical Society Reviews, Chemical Communications, Acta Chimica Sinica, Macromolecules, ACS Macro Letters, and Polymer Chemistry.
Eric Anslyn attended the California State University Northridge to receive his B.S. degree in Chemistry. After that he performed doctoral research at the California Institute of Technology under the direction of Dr. Robert Grubbs, and he received his Ph.D. in Organic Chemistry in 1987. From that year to 1989 he was a National Science Foundation postdoctoral Associate at Columbia University working with Dr. Ronald Breslow. He started his independent career at the University of Texas at Austin in 1989. He is currently the Welch Regents Chair of Chemistry and a University Distinguished Teaching Professor. Professor Anslyn’s research involves the use of physical organic chemistry principles in the development of enzyme mimics and synthetic receptors. Most recently, these receptors have been used to create practical molecular sensors.
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DOI: 10.1021/acs.chemrev.5b00352 Chem. Rev. 2015, 115, 6999−7000
