Investigation of the adducts formed by reaction of malondialdehyde

Investigation of the adducts formed by reaction of malondialdehyde with adenosine [Erratum to document cited in CA112(11):93606w]. Koni Stone, Mohamad...
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Chem. Res. Toxicol., Vol. 3, No. 2, 1990 169

Additions and Corrections Investigation of the Adducts Formed by Reaction of Malondialdehyde with Adenosine [Volume 3, Number 1, January/February 1990, pp 33-38]. KONISTONE,M ~ ~ I A M A D B. KSEBATI,and LAWRENCE J. MARNEW* Page 34. In line 11of the left-hand column of text, 35 ps should read 35 ms. Adducts M2G and M,A were proposed to result from reaction of a dimer and a trimer of malondialdehyde with guanine and adenine nucleosides, respectively. The putative dimer and trimer have been isolated and characterized by Golding et al. [Golding,B. T., Patel, N., and Watson, W. P. (1989) Dimer and trimer of malonaldehyde. J. Chem. SOC., Perkin Trans. 1, 668-6691,

Announcement NATO ADVANCED STUDY INSTITUTE: NEW TRENDS I N PHARMACOKINETICS

The Scientific Affairs Division of NATO under the program of the Advanced Study Institutes is sponsoring a school on “New Trends in Pharmacokinetics”, September 4-15, 1990, at the Ettore Majorana Centre for Scientific Culture, Erice, Sicily, Italy. The objective of this Advanced Study Institute is to present and discuss, in a tutorial form, the most recent methods for the study of the kinetic properties of drugs and chemicals, for the benefit of pharmacologists, pharmacists, and toxicologists working on research, development, and testing. Topics will include “The Role of Pharmacokinetics in the Design of New Drugs”, “Stereospecific Pharmacokinetics”, “Distribution and Pharmacokinetics”, “Pharmacokinetic Modeling of Monoclonal Antibodies”, “Interspecies Pharmacokinetic Scaling”, ”From Compartmental to Noncompartmental Models“, and “Pharmacokinetics of Anticancer and Anti-AIDS Drugs”. For information, contact Professor Giuliano Mariani, C.N.R. Clinical Physiology, via Savi 8,1-56100 Pisa, Italy, telephone (050)554065, or Dr. A. K. Thakur, Hazleton Laboratories America Inc., 9200 Leesburg Turnpike, Vienna, VA 22180, telephone (703) 893-5400.