J. Am. Chem. SOC. 1981, 103, 2129-2131 2129 lb ... - ACS Publications

Aldol Condensations of IC and Id with Representative. Aldehydes (Scheme 11)9 ratio. [a]"D optical purity imide R,CHO. 11a:12aa. 13. 13:14c. Id Me,CHCH...
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2129

J. Am. Chem. SOC. 1981, 103, 2129-2131 Table 11. Aldol Condensations of I C and I d with Representative Aldehydes (Scheme 11)9 imide

R,CHO

Id Id Id Id

Me,CHCHO n-C,H,CHO CH,CHO C,H,CHO

a

ratio 11a:12aa 98.4:1.6 98.9~1.1 99.6:0.4 92.4:7.6

Determined by GLC (ref 13).

[a]"D

13 -42.1" -27.3" -45.8" -17.1"

(1.8)d (2.1)e (1.7)f (4.l)g

optical purity 13:14c 97.8:2.2 99.4:0.6 >99.9: