JOURNAL OF NATURAL PRODUCTS® (LLOYDIA) P u b l i s h e d b y T H E A M E R I C A N SOCIETY O F P H A R M A C O G N O S Y and T H E LLOYD LIBRARY A N D M U S E U M 9 1 7 PLUM STREET, C I N C I N N A T I , O H I O 4 5 2 0 2 Editor
Associate
Managing Editor J A M E S Ε. R O B B E R S
S U S A N C. S T I T E S
School of Pharmacy and Pharmacal Sciences Purdue University W e s t Lafayette, Indiana 4 7 9 0 7 FAX (317) 4 9 4 - 7 8 8 0
c/o T h e Lloyd Library 9 1 7 P l u m Street Cincinnati, O h i o 4 5 2 0 2
Associate Editor and Book Review Editor
Editor J E R R Y L. M C L A U G H L I N
D A V I D G.I.
School of Pharmacy and Pharmacal Sciences Purdue University W e s t Lafayette, Indiana 4 7 9 0 7
D e p a r t m e n t of Chemistry Virginia Polytechnic Institute and State University Blacksburg, Virginia 2 4 0 6 1
KINGSTON
Editorial Advisory Board L Y N N R.
BRADY
T O M J. M A B R Y
J O H N P. R O S A Z Z A
Seattle, Washington
Austin, Texas
Iowa City, Iowa
JOHN M. CASSADY
MARVIN H. MALONE
USHIO SANKAWA
Columbus, Ohio
Stockton, California
Tokyo, Japan
CHING-JER CHANG
KOJI N A K A N I S H I
P A U L L. SCHIFF, J R .
West Lafayette, Indiana
N e w York, N e w York
Pittsburgh, Pennsylvania
G E O F F R E Y A. C O R D E L L
S. W I L L I A M P E L L E T I E R
MAURICE SHAMMA
Chicago, Illinois
Athens, Georgia
University Park, Pennsylvania
R A Y M O N D W.
G E O R G E R.
Y U Z U R U SHIMIZU
DOSKOTCH
PETTIT
Columbus, Ohio
Tempe, Arizona
Kingston, Rhode Island
N O R M A N R.
J. D A V I D P H I L L I P S O N
F R A N K R. S T E R M I T Z
Chicago, Illinois
London, England
Fort Collins, Colorado
WILLIAM FENICAL
PIERRE POTIER
V A R R O E. T Y L E R
La Jolla, California
Gif-sur-Yvette, France
West Lafayette, Indiana
FARNSWORTH
H E I N Z G. F L O S S
ROBERT VERPOORTE
Seattle, Washington
Leiden, The Netherlands
E D W A R D LEETE
HILDEBERT W A G N E R
Minneapolis, Minnesota
Munich, West Germany
JOURNAL OF NATURAL PRODUCTS ® (Lloydia) (ISSN 0163-3864) is published bimonthly in February, April, June, August, October, and December by The American Society of Pharmacog nosy at 4 1 Carleton Drive, Pittsburgh, PA 15243. Second-class postage paid at Pittsburgh, PA, and additional mailing offices. POSTMASTER: Send address changes to J O U R N A L OF N A T U RAL PRODUCTS®, P.O. Box 13145, Pittsburgh, PA 15243. All manuscripts and correspondence dealing -with editorial matters should be addressed to the editor. The title word for this journal for use in bibliographic reference is JOURNAL OF NATURAL PROD UCTS®, abbreviated as J. Nat. Prod. COMMERCIAL SUBSCRIPTIONS—Subscription orders from libraries, institutions, commercial firms, and similar organizations will be treated as commercial subscriptions. All matters related to com mercial subscriptions, such as billing, change of address, ordering procedures, etc., should be addressed to: Journal of Natural Products®, c/oDavidJ. Slatkin, P h . D . , Treasurer, American Society of Pharmacog nosy, School of Pharmacy, 1104 Salk Hall, University of Pittsburgh, Pittsburgh, PA 15261, U.S.A. Phone (412) 6 4 8 - 8 5 7 9 , FAX (412) 648-1086. Domestic Commercial Subscriptions: $ 120.00, including all addresses in the United States and pos sessions, the Dominion of Canada, and the Republic of Mexico. Foreign Commercial Subscriptions: $ 160.00, sent only by airmail to all other parts of the world, with air postage included in the higher rate. Orders for subscriptions are due and payable during the last quarter of the calendar year preceding the subscription year. Single copies: $ 2 5 . 0 0 plus postage. P R I N T E D B Y T H E S P A H R A N D G L E N N C O M P A N Y , C O L U M B U S , O H I O 43215
Date of Issue—January 8, 1991