Focus
J.T.Baker ®
RESEARCH PRODUCTS
Separate thousands of racemic mixtures by chromatography
2 c o l u m n s — a r e o p t i m a l for D L L In fact, t h e entire effluent from e x t r e m e ly n a r r o w bore L C capillary columns can be directed into an M S ion source with D L I p r o b e s t h a t are available. S o m e say t h a t t h e D L I interface, with some design modification, can also be m a d e c o m p a t i b l e with 1-mm or even 2 - m m microbore columns. A l t h o u g h t h e j u r y is still o u t o n which L C / M S interface will become m o s t p o p u l a r , some feel t h a t t h e r m o spray, n o t D L I , is winning t h e c o m p e tition. As one c h r o m a t o g r a p h e r p u t it, " T h e r m o s p r a y seems m o s t promising r i g h t now. T h e m a n u f a c t u r e r s are h o m i n g in on t h e r m o s p r a y as t h e way t o go."
There is no question about it — people d o i n g microanalysis should b e using microbore. —Sjoerd van der Wal, Varian
J.T. Baker Research Products can supply all the appropriate materials you need for chroma tographic chiral separations. B A K E R B O N D ™ Chiral Phase HPLC Columns use high purity DNBPG ((R)-N-3,5-dinitrobenzoylphenylglycine) bonded to aminopropyl silica to separate a wide range of optical isomers. Up to 10 mg of sample can be ap plied to the column in a single injection. Preparative chiral sorbents, in 40 u.m particle size, are also available for scale-up of separa tions. In addition, longer column life can be achieved with our Chiral Column Regenerating Solution. For more information, call or write today. J.T. BAKER RESEARCH PRODUCTS 222 Red School Lane Phillipsburg, NJ 08865 USA
(201) 859-2151 Outside New Jersey (800) 526-0239 Gross Gerau. W. Germany · Deventef. Holland Mexico City, Mexico · Singapore · Sydney, Australia
©J.T. Baker Chemical Co. 1983 CIRCLE 21 ON READER SERVICE CARD
1036 A
Despite t h e n o r m a l a m o u n t of con troversy expected for an analytical t e c h n i q u e in a s t a t e of r a p i d develop m e n t , future prospects for microcol u m n LC are promising. " W i t h a new t e c h n i q u e , " said Van d e r Wal, " t h e r e is always a wave in t h e beginning w h e n people t h i n k it will solve all t h e problems. W e ' r e now a t t h e stage t h a t we see it w o n ' t solve all t h e p r o b l e m s , b u t we can see a n u m b e r of specific applications. I t h i n k t h e r e is n o ques tion a b o u t it—people doing micro analysis should be using m i c r o b o r e . " N o v o t n y said t h a t c o n t i n u e d micro column L C d e v e l o p m e n t will r e q u i r e "significant d e p a r t u r e s in t e r m s of technological a p p r o a c h e s , which is w h a t a lot of m o d e r n analytical c h e m istry is a b o u t . Obviously, some people m a y t h i n k it is ridiculous to work with such small volumes, b u t people in medical research, for example, will tell you t h a t t h e r e is a g r e a t d e m a n d for developing such t e c h n i q u e s . " Stuart A. Borman References (1) Anal. Chem. 1984,56, 804 A. (2) McGuffin, V.L. LC 1984, 2, 282-88. (3) Novotny, Milos. Anal. Chem. 1981, 53, 1294-1308 A. (4) Majors, Ronald E. LC 1983,1, 80-81. (5) Guiochon, G.; Colin, H. In "Micro column High-Performance Liquid Chro matography"; Kucera, Paul, Ed.; Else vier: Amsterdam, 1984; Chapter 1. (6) Majors, Ronald E. LC 1983,1, 488-95.
· ANALYTICAL CHEMISTRY, VOL. 56, NO. 9, AUGUST 1984
CHEMTECH Why do so many innovators in all chemical fields turn to C H E M T E C H each month?
ΨΨ
. . . O n e of the
best condensed technical news sources I g e t . . . Outstanding melding o f social, political, and scientific literature . . . T h e fresh glibness and tonguein-cheek style are unique and w e l c o m e d . . . I am impressed w i t h the quality, scope and personal touch o f the articles . . . I almost dread it when each issue arrives because I k n o w I will take the time, w h e t h e r I have it t o spare o r not, t o read it f r o m cover t o cover.
M
Join your satisfied colleagues and subscribe to the innovator's magazine... CHEMTECH
Call now to order: 800-424-6747
