Local Anesthetics. IV.1 The Synthesis of Local Anesthetic 3,4

tor organic compounds, such as nitrous oxide, ether, chloro-. Essentially this is the problem. Cocaine is a naturally form, ethyl chloride, etc. Local anesthetics.

where the patient suffers temporary loss of conscious- ness; andlocal, when the patient retains consciousness during the operation. Generalanesthetics may be ...

(i) H. R. .1. Chance and J. Lohstein, J. Pharmacol. Erp Ther., 83,. (8) M. 4. Patel, J. Erp. Bzol., 6, 1. 64 (1968). 20'3 (1944). Synthesis of Compounds with Potential.

Jul 16, 1970 - The possibility that Ar- (acylamino) phenothiazines and iminodibenzyls reported herein, might possess local anesthetic properties similar to ...

styrils (I) from which a series of aminoalkoxy de- rivatives (III) has been obtained according to the procedure outlined by formulas I-III. In order to be able to study ...

Some Colored Local Anesthetics. 901. [Contribution from the. Chemical Laboratory of. Washington University]. Some ColoredLocal Anesthetics. By John H.

(1) P. N. Bhargava and B. T.Baliga, J. Indian Cltem. Soc.. 35, 807 (1958u. (2) P. N. BhargaYa and K. A. Jose, ibid.. 37, 314 (1960). (3) P. X, Bhargava and M. G.R. ...

local anesthesia, both subcutaneously and topi- cally.' Although these compounds possessed low toxicities they were quite irritating to the tissues. This irritation ...

In our studies of aminoacylanilides as local anesthetics we have previously reported a few alkoxyalkylaminoacylan- ilides.1 Here we present the results of ...

substituted formamidines which showed local anesthetic activity. He also prepared form- amidines in which the two N-substituted phenyl groups were substituted ...