under the skin of pregnant guinea pigs. After allowing sufficient time for the compound to filter through the mother's body into its offspring's circulatory system, thescientists removed the embryo and analyzed it chemically. Despite careful testing of the vitamin C found in the embryo, highly-sensitive Geiger counters failed to pick up any trace of radioactive carbon. Thus it became apparent that the vitamin present could have come only from food eaten by the parent guinea pig. Further Studies. Another problem the research group is attacking, is the disappearance of vitamin C in the adrenal glands after an injection of ACTH. It has been found that test animals injected with the hormone experience a sharp drop in the amount of ascorbic acid in their adrenals. Several possibilities have already been tested, and the evidence so far indicates that the vitamin does not disintegrate into other compounds hut leaves the adrenals intact. Superconcentrated G r a p e Juice C a n Be D i l u t e d Sîx-to-One A "superconcentrated" grape juice which can be diluted with six parts of water to one part of juice has been developed by scientists at the Eastern Regional Research Laboratory, Department of Agriculture. A four-ounce can of the new product yields 70% more juice than the present six-ounce can which is diluted only three to one. The process for making t h e concentrate involves stripping the juice of its volatile or aromatic flavors and concentrating these stripped flavors to about 150 times the flavor strength of fresh juice. After the removal of pectin to prevent gelling, the juice is concentrated and t h e concentrated flavors returned to it. The process was first perfected by ERRL in 1944 for apple juice concentration.
LOF R e s e a r c h G r a n t s Six major projects dealing with fundamental research in glass, including some preparing for the oncoming application of atomic force to industry, are now being supported by Libbey-Owens-Ford Glass Co. Among the special projects sponsored by LOF is one dealing with fundamental glass studies related to nuclear physics and atomic energy in connection with the Phoenix Project at the University of Michigan, Ann Arbor, Mich. The overall project is bringing together more than 400 scientists in widely scattered fields to pool their work to "make a united attack on the problems of how to live with the atom." Robert L. Hess will surpervise the glass studies. In connection with the LOF program there will be graduate fellowships directed by Dr. Hess at University of Michigan. Lihhey-Owens-Fmd is also sponsoring Ο L U Μ Ε
3 0, Ν Ο .
BENZOPHENONE (diphenyl ketone) is a n intriguing intermediate w i t h a n active carbonyl g r o u p c o n necting t w o phenyl groups. Its use in perfumes is well k n o w n , but its potential in synthesis may still b e e x p l o i t e d . It has b e e n suggested as an intermediate for certain anrihistaminics, hypnotics and other pharmaceuticals; insecticides; dielectric m e d i a ; a n d as a gas a b s o r b i n g medium. ΚAY-FRIES
SPECIFICATIONS..,
melting point
4 y
.
Φ
46,5° — 48.5° C.
m o l t e n color
®
below l O O H a z e n Scale
odor
φ
characteristic (rosegeranium type)
Typical reactions of B E N Z O P H E N O N X RCH2MgX
+
C 6 H 5 COC 6 H 5
H20
(CoH5)2C(OHOCH2R - f MgX(OH) Substituted Benzhydrol
Grig πα rd compound
RESEARCH
V
benzophenone
XCRHCOOC 2 H 5 + H 2 + C 6 H 5 C O C 6 H j ^ ° M (QH 5 ) 2 C(OHJCRHCOOC 2 H 5 -f HX Subst. hafoacid ester
ethyl 3-hydroxy*-3, 3-diphenyI2-subst. piropforaate +
H2
C6H5COC6H5
catalyst
(C6H5)2CHOH benzhydrol
the reduction, other products may be obtained by varying t h e conditions. H202
•+
QH5COC6H
C6H5C0OC^H.-,-f- H 2 0
5
hydrogen peroxide C02
+ H? +
. O C T O B E R
phenyl benzoat^
QH 5 COC € i H 5
Na
(C 6 H 5 )i.C(OH)C0OH benzîlîc acid
TECHNICAL
BULLETIN
AVAILABLE
American-British Chemical Supplies, Inc. Selling Agents for
KAY-FRIES CHEMICALS, INC. !iLS, IIC. }QQ Madison Avenue. New York 16, Ν. Υ".
2 0,
1952
MUtray Hill 6*066!
4393
THE CHEMICAL WORLD THIS WEEK
c* ^
three special research projects at t h e Battelle Memorial Institute in Columbus. O n e of those deals with a study of fundamental principles of glass grinding, another t h e oxidation potential of molten glass, and a third covers fundamental studies relating to metals and ceramic bodies. At Armour Research Foundation in Chicago there is a project to study t h e physical and chemical properties of solids including glass and films on glass. L O F Glass is also cooperating with other glass companies in t h e establishment of t h e Institute of Silicate Chemistry a n d Related Sciences h e a d e d by Wilhelm Eitel, at the University of Toledo.
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MULTI-FEED CHEMICAL FEED!
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Survey of Food and Nutrition Research A third survey of food and nutrition research in the United States is being u n dertaken by the National Academy of Sciences-National Research Council under contract with the U. S. Department of Agriculture. T h e two previous surveys published in 1948 a n d 1950 afforded a compilation of projects, organizations, a n d professional personnel t h e n current in this field. All phases of food a n d nutrition research active in academic, governmental, a n d industrial laboratories were included. This consolidation of the research work a n d workers into a central register has afforded a basis for t h e coordination a n d evaluation of research programs in t h e area. T h e third survey will follow t h e plan of the earlier surveys a n d will bring the information u p to elate. In addition, it will include suggested food a n d nutrition research projects in areas where further work is indicated.
H i l / '
)
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• FOR THE ANSWER
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Despite their time-tested d e p e n d a b i l i t y , Manzel Chemical Feeders are priced much lower than you might expect, They can be iodividiuilly engineered for most applications. Write for details today.
Grants and Fellowships a t N. D. Agricultural College T h e school of chemical technology of the North Dakota. Agricultural College has recently received research grants, totaling well over $8000 for support of basic research in the various fields of chemistry. T h e latest grant is the Archer-DanielsMidland Co. Senior Award in Chemistry (if $500 which has been assigned to Donald K. \\'ahl«*,n-n. T h e same Minneapolis firm had previously forwarded a check for $750 to defray the expenses of a graduate student, in chemistry. Dale Noaek ha- been named as the recipient of the award Λ\\Λ will .study the relationship of acetone tolerance to the physical and paint making qualities o! bodied nils. T h e Catnapnote Corp. of Toledo, this Mimiuei granted a sum of $21'H) to Mipport a basic research program at the graduate le\t-l in the field of highway traffic paints. S.mi Vianish has been assigned to the pioirct. T h e Krnest, T, Trigg. Foundation I of Philadelphia l'a., has granted three . lelloVNships of $750 . At p r e s e n t his l a b is in tin bavi-iiieiit (»t t h e m a i n c h c m i s t i x building Must" ol T h e e q u i p m e n t t h a t w i l l h e m .tailed •;, t h ' · n e w h u i i f l i n g h a s h'>en d e s i g m (I .. m1 r">uilt b> D r . C i a u q u e a n d In·, < ovvoiki rs, t h e l i q u e l i e r w i l l lie. of t i n · .I.Mll. S-'l ill m ι-on e x p a u s i o i i tyj)e a n d \sill pioduc* a b' -ut i η l i t e r s oi l i t j u i d h e l i u m a n hum T h e v a r e a l s o h i u ' I d i n g a n 8-ίθ»ι hors"|)ie,\i-i mayjM-t. T h e nregnctt is r a t e d ir a b - i i t i ΠΟ,ίΜΗ) o e r s t e d s a n d is a M'lennif b . i t n
