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XtalFluor reagents are crystalline dialkylaminodifluorosulfinium tetrafluoroborate salts. They are useful for the deoxofluorination of hydroxyl and carbonyl moieties when used in conjunction with a promoter.
Representative Scope
Advantages of XtalFluor salts • Air-stable solids • Enhanced thermal stability over DAST and other structurally similar deoxofuorination reagents • Does not generate free HF under anhydrous conditions • Broad substrate scope • Predictable and high chemoselectivity
Aldrich XtalFluor Reagents
Aldrich.com/xtalfluors Multi-kilogram quantities available through Manchester Organics ©2013 Sigma-Aldrich Co. LLC. All rights reserved. Aldrich and Sigma-Aldrich are registered trademarks of Sigma-Aldrich Co. LLC. XtalFluor-E and XtalFluor-M are registered trademarks of OmegaChem Inc.
81008_ALD 2012 Xtalfluor Print Ad.indd 1
References: (1) Couturier, M. et al. Org. Lett. 2009, 11, 5050. (2) Couturier, M. et al. J. Org. Chem. 2010, 75, 3401.
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