Biosynthesis of the C15 macrolide antibiotics. 1. Biochemical origin of the four oxygen atoms in brefeldin A. Clayton T. Mabuni, Luigi Garlaschelli, Robert A.
Jul 7, 1982 - C-6), 2.23 (1 H, m, C-25); MS, m/z 412.37050 (M+, C29H480, 40; caled. ..... aminosyltylonolide (4)6 in 10 mL of chloroform was added at 0.
Abstract: The biochemical origin of the four oxygen atoms present in brefeldin A (1). a 16-membered macrolide antibiotic, is determined by feeding experiments ...
Jun 30, 2015 - issues call for new antibiotics to fill this gap.3 To this end, we became interested in fidaxomicin (1, tiacumicin B, lipiarmycin. A3),4 which inhibits RNA polymerase in bacteria and shows high activity against drug resistant strains o
May 27, 2016 - Belfast, Stranmillis Road, Belfast BT9 5AG, Northern Ireland, United Kingdom ..... sant (+)-SW-163A,6 in accord with Shin-ya,s 2007 limited.
May 27, 2016 - Total Synthesis of the GRP78-Downregulatory Macrolide (+)-Prunustatin A, the Immunosuppressant (+)-SW-163A, and a JBIR-04 Diastereoisomer That Confirms JBIR-04 Has Nonidentical Stereochemistry to (+)-Prunustatin A. Soraya Manaviazar, P
May 27, 2016 - Our new (+)-prunustatin A campaign began with a repetition of the synthesis of β-aldehydo ester 16,(9) which was typically prepared in 67% yield from 17 by ..... A well-accepted approach for interfering with β-sheet formation is the
Aug 1, 1986 - Leto, T. L., Roseman, M. A., & Holloway, P. W. (1980). Biochemistry 19, 1911. Mayer, L. D., Hope, M. J., & Cullis, P. R. (1986) Biochim. Biophys.
Michael J. Parnham , Vesna Erakovic Haber , Evangelos J. Giamarellos-Bourboulis , Gianpaolo Perletti , Geert M. Verleden , Robin Vos. Pharmacology ...
