Macromolecule diffusiophoresis induced by ... - ACS Publications

Contribution from the Department of Chemistry, Texas Christian University, ... of Chemistry & Biochemistry, Box 298860, Texas Christian University, Fo...
0 downloads 0 Views 537KB Size
Subscriber access provided by Kaohsiung Medical University

Interface Components: Nanoparticles, Colloids, Emulsions, Surfactants, Proteins, Polymers

Macromolecule diffusiophoresis induced by concentration gradients of aqueous osmolytes Lara R Lechlitner, and Onofrio Annunziata Langmuir, Just Accepted Manuscript • DOI: 10.1021/acs.langmuir.8b02065 • Publication Date (Web): 24 Jul 2018 Downloaded from http://pubs.acs.org on July 27, 2018

Just Accepted “Just Accepted” manuscripts have been peer-reviewed and accepted for publication. They are posted online prior to technical editing, formatting for publication and author proofing. The American Chemical Society provides “Just Accepted” as a service to the research community to expedite the dissemination of scientific material as soon as possible after acceptance. “Just Accepted” manuscripts appear in full in PDF format accompanied by an HTML abstract. “Just Accepted” manuscripts have been fully peer reviewed, but should not be considered the official version of record. They are citable by the Digital Object Identifier (DOI®). “Just Accepted” is an optional service offered to authors. Therefore, the “Just Accepted” Web site may not include all articles that will be published in the journal. After a manuscript is technically edited and formatted, it will be removed from the “Just Accepted” Web site and published as an ASAP article. Note that technical editing may introduce minor changes to the manuscript text and/or graphics which could affect content, and all legal disclaimers and ethical guidelines that apply to the journal pertain. ACS cannot be held responsible for errors or consequences arising from the use of information contained in these “Just Accepted” manuscripts.

is published by the American Chemical Society. 1155 Sixteenth Street N.W., Washington, DC 20036 Published by American Chemical Society. Copyright © American Chemical Society. However, no copyright claim is made to original U.S. Government works, or works produced by employees of any Commonwealth realm Crown government in the course of their duties.

Page 1 of 24 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60

Langmuir

Macromolecule diffusiophoresis induced by concentration gradients of aqueous osmolytes

Lara R. Lechlitner, and Onofrio Annunziata* Contribution from the Department of Chemistry, Texas Christian University, Fort Worth, Texas 76129, USA

Contribution from the Department of Chemistry & Biochemistry, Texas Christian University, Fort Worth, Texas 76129.

*

To whom correspondence should be addressed:

Department of Chemistry & Biochemistry, Box 298860, Texas Christian University, Fort Worth, Texas 76129, USA. Phone: (817) 257-6215. Fax: (817) 257-5851. E-mail: [email protected]

KEYWORDS: polyethylene glycol, multicomponent diffusion, hydration, binding Running title: Macromolecule Diffusiophoresis by osmolytes.

*

To whom correspondence should be addressed: Phone: (817) 257-6215. Fax: (817) 257-5851. E-mail: [email protected] 1 ACS Paragon Plus Environment

Langmuir 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60

Page 2 of 24

ABSTRACT Diffusiophoresis is the migration of a particle in a fluid induced by the concentration gradient of another solute. We have experimentally investigated diffusiophoresis of a neutral macromolecule, polyethylene glycol (PEG; molecular weight, 20 kg·mol-1), in water induced by concentration gradients of osmolytes. Three osmolytes were examined: Trimethylamine-N-oxide (TMAO) diethylene glycol (DEG) and urea. PEG diffusiophoresis coefficients were obtained from measurements of multicomponent-diffusion coefficients at 25 ºC using Rayleigh interferometry. Osmotic diffusion coefficients, characterizing osmolyte diffusion from high to low PEG concentration, were also extracted. PEG diffusiophoresis was found to occur from high to low osmolyte concentration in all cases, with magnitude increasing in the order urea