Journal of Medicinal Chemistry Published by the American Chemical Society at 20th and Northampton Sts., Easton, Pennsylvania
EDITOR ALFRED BURGER Department of Chemistry, University of Virginia, Charlottesville, Virginia
22901
ASSISTANT EDITOR MANFRED E. WOLFF University of California (San Francisco)
EDITORIAL ADVISORY BOARD L E O G. ABOOD University of Rochester
C. R. CREVELING National Institutes of Health
EDWARD J. MODEST Children's Cancer Research Foundation
BARRY M. BLOOM Chas. Pfizer Medical Research Laboratories
CORWIN HANSCH Pomona College
HOWARD J. SCHAEFFER State University of New York at Buffalo
CHESTER J. CAVALLITO University of North Carolina
HENRY G. MAUTNER Yale University School of Medicine
JOHN M. STEWART The Rockefeller University CHARLES L. ZIRKLE Smith Kline and French Laboratories
Κ. Κ. C H E N Indiana University School of Medicine
EX-OFFICIO:
EDWARD L. SCHUMANN The Upjohn Company (Secretary, Division of Medicinal Chemistry, American Chemical Society)
SENIOR PRODUCTION EDITOR CHARLES R. BERTSCH Research Journals Production Office, 20th and Northampton Sts., Easton, Pennsylvania
connections, and claims for missing numbers should be sent to the Subscription Service Department, American Chemical Society, 1155 Sixteenth St., N.W., Washington, D. C. 20036. Changes of address for this journal must be received four weeks before the first issue is to go to the new address. Please include both old and new addresses, with ZIP codes, and a mailing label from a copy of one of your ACS publica tions. Subscriptions should be renewed promptly, to avoid a break in your series. Claims for missing numbers will not be allowed (1) if received more than sixty days from date of issue plus time normally required for postal delivery of journal and claim, (2) if loss was due to failure of notice of change in address to be received before the date specified in the preceding para graph, or (3) if the reason for the claim is "missing from files." Subscription rates for 1968: to members, $10.00 per year; to nonmembers, $20.00 per year. Postage to Canada and countries in the Pan-American Union, $1.00; all other countries, $1.50. Single copies: $5.00. Postage, single copies: to Canada and countries in the Pan-American Union, $0.15; all others, $0.20. Rates for back issues from 1962 to date are available from the Special Issues Sales Department, 1155 Sixteenth St., N.W., Washington, D. C. 20036.
© Copyright, 1968, by the American Chemical Society. Published bimonthly by the American Chemical Society at 20th and Northampton Sts., Easton, Pennsylvania 18042. Second-class postage paid at Easton, Pennsylvania. Manuscripts for publication and books for review in this journal should be sent to the Editor, ALFRED BURGER, Department of Chemistry, University of Virginia, Char lottesville, Virginia 22901. Correspondence regarding accepted papers, proofs, and reprints should be directed to Research Journals Produc tion Office, American Chemical Society, 20th and North ampton Sts., Easton, Pennsylvania 18042. Senior Pro duction Editor: CHARLES R. BERTSCH. Assistant Senior Production Editor: MARIANNE C. BROGAN. Assistant Editor:
JOAN F. WITIAK.
Advertising Office: Reinhold Publishing Corporation, 430 Park Ave., New York, New York 10022. The American Chemical Society and the Editors of the Journal of Medicinal Chemistry assume no responsibility for the statements and opinions advanced by contributors to this journal. Business a n d Subscription I n f o r m a t i o n Remittances and orders for subscriptions and for single copies, notices of changes of address and new professional
AMERICAN CHEMICAL SOCIETY PUBLICATIONS 1155 Sixteenth St., N.W., Washington, D. C. RICHARD L. KENYON Director of Publications
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20036 DAVID E. GUSHEE Publication Manager, Journals
