Article pubs.acs.org/JAFC
Matrix Behavior during Sample Preparation Using Metabolomics Analysis Approach for Pesticide Residue Analysis by GC-MS in Agricultural Products Kuniyo Sugitate,*,†,§ Machiko Saka,‡ Takeshi Serino,# Sadao Nakamura,† Akira Toriba,§ and Kazuichi Hayakawa§ †
Agilent Technologies Japan, Ltd., 9-1 Takakura-cho, Hachioji-shi, Tokyo 192-8510, Japan The Institute of Environmental Toxicology, 4321 Uchimoriya-machi, Joso-shi, Ibaraki 303-0043, Japan # Agilent Technologies Inc., 5301 Stevens Creek Boulevard, Santa Clara, California 95051, United States § Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-cho, Kanazawa-shi, Ishikawa 920-1192, Japan ‡
ABSTRACT: The detailed matrices and their behaviors during pesticide residue analyses were clarified using a metabolomics analysis approach. The matrix profile was investigated using two different extraction solvents, acetone and acetonitrile. Acetone extracted the matrix components with a wide range of log PO/W values. Components with log PO/W values >10, such as sterols and tocopherols, and components with log PO/W values
