Metabolism of carbon-14-labeled hexazinone in the rat

1980, 28, 303-306. 303. Metabolism of 14C-Labeled Hexazinone in the Rat. Robert C. Rhodes* and Richard A. Jewell'. The active ingredient in Velpar wee...
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J. Agric. Food Chem. 1980, 28,303-306

303

Metabolism of 14C-Labeled Hexazinone in the Rat Robert C. Rhodes* and Richard A. Jewell'

The active ingredient in Velpar weed killer is 3-cyclohexyl-6-(dimethylamino)-l-methyl-l,3,5-triazine2,4(1H,3H)-dione (hexazinone). When a rat was given a single oral dose of radiolabeled hexazinone by intragastric intubation, the radioactivity was eliminated within 72 h in the urine (61%) and feces (32%). Trace amounts of radioactivity were also found in the gastrointestinal tract (0.06%) and expired air (0.08%). No radioactivity (