METHYL 3-CYANOPROPIONATE Hydrolysis NCCH2CH2COOCH3 + Ba(0H)2 - * · HOOCCH2CH2COOH Succinic Acid
Aminolysis NCCH2CH2COOCH3 4- HOCH2CH2NH2 No
I 0=1
Solvent
; = o
Ν CH2CH2OH N-(2-hydroxyethyl)~succinimide
NH NH II II NCCH2Cri2COOCH3 + H 2 N - C - N H - C — N H 2 NH2 1ST
^ N
H 2 N X ^ N ^ ^CH2CH 2 CN 3-(2,4-diamino-6-s-triazlnyl)propion/tri/e
Reduction NCCH2CH2COOCH3
New intermediate undergoes reactions of both nitrile and ester groups Methyl 3-cyanopropionate (MCP), a new, high-boiling, difunctional intermediate, brings the syntheses of many unusual prod ucts into the area of practical chemistry. A few of the more interesting reaction routes possible with MCP are given at the left. MCP also shows unique potential as a polar solvent. Write to Dept. SP-22 for samples, and literature giv ing many more reactions of i methyl 3-cyanopropionate. ChemicaL· for Industry
H2 , KI . X >
(Ni)
I
X
N
X
J=sO
I H 2-pyrrolidone
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