D E C E M B E R 10, 1939
NEWS EDITION
769
MINERAL METABOLISM by Alfred T. Shohl Research Associate in Pediatrics, Harvard University
A. C. S. Monograph
No.
82
Unquestionably the most comprehensive and authoritative work on this vital subject! Chemists are becoming more and more concerned with the most intricate chemical plant of all—the human body. This is attested by the fact that at the recent Boston meeting of the American Chemical Society, a large proportion of the papers dealt with various aspects of medicine and health. The chemical reactions by which the body controls its temperature, regulates its utilization of food and keeps the composition of blood and other fluids constant, is one of the most active fields of research to-day. Indeed, as was pointed out in a recent editorial in the New York HeraldTribune "the next age of medicine promises to be the chemist's." Knowledge of the effect of minerals on the structure and functions of the body has expanded so rapidly that this volume will be essential to biochemists, pharmacists, biolo gists, physiological chemists and to all research workers in the food and drug industries. It clearly and definitely de scribes the role of minerals in the structure and functions of the human body. Presented as a concise but thoroughgoing account, the subject matter constitutes a simplified digest and interpretation of the vast amount of research carried on in this field during the past decade. Deposition of calcium by the blood, mineral requirements during preg nancy and lactation, the mechanism of acid-base equilibrium and secretions, excretions and water metabolism are some of the pertinent subjects discussed. This volume will also be helpful to dieticians, pediatri cians, general practitioners and pre-medical students. Much valuable statistical information is presented on the effect of minerals on nutrition, on the diseases of tetany and rickets, and on mineral balance studies of animals, infants and adults. An ample bibliography is given at the end of each chapter, enabling those interested to obtain a wealth of further information. The author, Dr. Alfred T. Shohl, is a recognized authority on pediatrics and the physiology of acid-base and mineral metabolism. A research associate of Harvard University, he is the author of many important physiological papers, and has had extensive experience as a consulting pediatrician.
394 Pages
Illustrated
CONTENTS INTRODUCTION MINERAL COMPOSITION OF T H E BODY Body Water—Ash of the Body—Min erals of the Whole Body—Minerals of the Organs—Relation Between Posi tive and Negative Minerals in Body Structure—Relative Mineral Composi tion of Infant and Adult—Mineral Accretion. SECRETIONS AND EXCRETIONS General Considerations—Alimentary Secretions—External Secretions—Ex cretions—Changes in Volume and Composition of Body Fluids. INTERNAL SECRETIONS Adrenal Glands—Pituitary Gland— Parathyroid Glands—Thyroid Gland— Other Glands. TOTAL BASE, CHLORIDE. AMMO NIUM AND BICARBONATE Total Base—Sodium—Potassium— Sodium and Potassium—Chloride— Ammonium—Bicarbonate. CALCIUM AND MAGNESIUM Calcium in the Blood—Calcification— Tetany—Magnesium. PHOSPHORUS SULFUR IRON IODINE TRACES WATER METABOLISM Occurrence of water in the Body— Water Excretion—Water Require ment—Control Mechanisms—Rela tion of Mineral Intake to Water Me tabolism—Water Insufficiency and Ex cess. ΑΝΙΟΝ-CATION RELATIONSHIPS Mechanism of Acid-Base Equilibrium— Excretion of Anions and Cations—Stor age and Depletion—Positive and Nega tive Mineral Intake—Mineral Cationogen—Excess Balance—Fasting. MINERAL INTAKES, BALANCES AND REQUIREMENTS Mineral Intake—Balance Studies— Pregnancy and Lactation—Mineral Requirements.
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