Contents
FEATURES
High-Resolution images. Page 23 A.
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On the Cover. Near-Field Scanning Optical Microscopy. The resolution in conventional microscopy is limited by the wavelength of light. Near-field scanning optical microscopy (NSOM) is designed to avoid diffraction limits, providing resolution of nanometer-sized samples. Hitoshi Shiku and Robert C. Dunn of the University of Kansas describe the concepts behind NSOM and illustrate some of its applications.
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Capillary Array Electrophoresis DNA Sequencing. As scientists move from sequencing genes to chromosomes to entire genomes, analytical instrumentation must be able to rapidly handle growing demands. Indu Kheterpal and Richard A. Mathies of the University of California-Berkeley describe capillary array electrophoresis, which uses multiple capillaries in parallel for high-throughput DNA sequencing.
NEWS 15 A
High-throughput DNA sequencing. Page 31 A.
Carbohydrates with an affinity for proteins. Page 15 A.
Analytical Currents Guiding light. • Low-affinity ligands. • No laser required. • Hybrid mass spectrometer for electrospray. • Biomimetic sensor for protein toxins. • Ion mobility simplifies mass spectra. • Interfacing CE-ICPMS. • Sweeping for enhanced sensitivity. • In the clouds.
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Science Looking for mosquito attractants. No one knows why mosquitoes are more attracted to one person than another, but Ulrich R. Bernier of the U.S. Agricultural Research Service Center for Medical, Agricultural, and Veterinary Entomology and co-workers at the University of Florida are developing an analytical method that could find the answer. • Modulated sensor. How can a sensor "see" through cloudy solutions or materials? Joseph Lakowicz and colleagues from the University of Maryland School of Medicine describe a method that uses two fluorophores to modulate the fluorescence emission and reveal analyte concentration. • Rapid angle on wood stiffness. Ward Robinson and coworkers at the University of Canterbury (New Zealand) use X-ray diffraction with a charge-coupled device to determine properties of various woods.
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Business Dionex acquires Softron. • Analect becomes part of Orbital.
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People Therese M. Cotton. • New Advisory Board and A-page Advisory Panel members appointed.
"This article is also available on the Web at http://pubs.acs.org. under "Hot Articles"
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Analytical Chemistry News & Features, January 1, 1999
ANALYTICAL CHEMISTRY JANUARY 1, 1999/VOL. .7 NO. . ANCHAM 1 A - 6 6 A/1-284 (1999) ISSN 0003-2700
DEPARTMENTS 5 A
Editorial Mentoring—one of the most important acts. Mentoring is a prolonged— even lifetime—interaction. For this reason it is important that chemists understand it themselves.
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In AC Research
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Product Review Microplatefluorometersreach critical mass. From basic units to systems optimized for high-throughput screening of 1536-well plates, there is a choice of microplate fluorometers.
Welllead. Page 39 A.
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A/C WebWorks† A tunnel too far: Virtual private networks. The Internet is like a CB radio— anyone with some technical expertise can tap into your messages. Ray Dessy discusses how tunneling can be used to send sensitive material securely over the Web.
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Meetings HPCE '99 in Palm Springs, CA. • Conferences. • Short courses.
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Books and Software Getting the basics of NMR. A Complete Introduction to Modern NMR Spectroscopy ii seviewed by John D. Roberts so fhe California Institute oo Technology. • A tool for understanding GFAAS. A Practical Guide to Graphite Furnace Atomic Absorption Spectrometry is reviewed by Gary D. Rayson of New Mexico State University. New uses of MS. Mass Spectrometry of Biological Materials is reviewed by John R. Yates of the University of Washington. • Books received. • Software released.
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N e w Products A fluorometer, an HPLC autosampler, and a robotic vial autosampler are featured. • Instrumentation. • Literature. • Column.
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Instructions to Authors
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Copyright Status Form
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Information Express
World wide tunnel. Page 44 A.
1C AC Research Contents 1 - 2 8 3 AC Research 284
Author Index
tincludes supporttng information that is available free of charge on the onterneI (http://pubs. acs. org/ac).
Registered in U.S. Patent and Trademark Office © Copyright 1998 by the American Chemical Society
Analytical Chemistry News & Features, January 1, 1999 3 A
