Article pubs.acs.org/JACS
Multicolored pH-Tunable and Activatable Fluorescence Nanoplatform Responsive to Physiologic pH Stimuli Kejin Zhou,† Haoming Liu,‡ Shanrong Zhang,†,§ Xiaonan Huang,† Yiguang Wang,† Gang Huang,† Baran D. Sumer,∥ and Jinming Gao*,†,⊥ †
Department of Pharmacology, Simmons Comprehensive Cancer Center, ‡Department of Biochemistry, §Advanced Imaging Research Center, and ∥Department of Otolaryngology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States ⊥ Department of Chemistry, University of Texas at Dallas, Richardson, Texas 75083, United States S Supporting Information *
ABSTRACT: Tunable, ultra-pH responsive fluorescent nanoparticles with multichromatic emissions are highly valuable in a variety of biological studies, such as endocytic trafficking, endosome/lysosome maturation, and pH regulation in subcellular organelles. Small differences (e.g.,
