Anal. Chem. 2011, 83, 109–117
Multiresidue Analysis of Multiclass Pesticides in Lavandin Essential Oil by LC/MS/MS Using the Scheduled Selected Reaction Monitoring Mode Yoann Fillaˆtre,†,‡ David Rondeau,*,§ Brice Bonnet,| Antoine Daguin,‡ Alain Jadas-He´cart,⊥ and Pierre-Yves Communal*,‡,⊥ Groupement Interre´gional de Recherche sur les Produits Agropharmaceutiques (GIRPA), 8 rue Becquerel, Angers Technopole, 49070 Beaucouze´, Institut des Sciences et Technologies Mole´culaires d’Angers (MOLTECH), CNRS UMR 6200, and Laboratoire d’Etudes Environmentales des Syste`mes Anthropise´s (LEESA), Universite´ d’Angers, 2 boulevard Lavoisier, 49045 Angers Cedex 01, Laboratoire Chimie et Electrochimie Mole´culaires et Chimie Analytique (CEMCA), CNRS UMR 6521, Universite´ Europe´enne de Bretagne a` Brest, 6 avenue Le Gorgeu, 29238 Brest Cedex 03, and L’Ore´al Recherche, 1 avenue Euge`ne Schueller, 93600 Aulnay sous Bois, France In this paper we describe the development of the first multiclass pesticide residue method applied to essential oils. A total of 70 pesticides covering a wide range of polarity and currently used on essential oil crops have been included in the method. The procedure consists of a 10-fold dilution of lavandin essential oil followed by a direct injection analysis by liquid chromatography/tandem mass spectrometry. The system used is an API 4000 QTrap equipped with an electrospray ionization interface and operating in scheduled selected reaction monitoring acquisition mode. Matrix effects were evaluated by comparing the slopes of matrix-matched and solvent-based calibration curves. Weak signal suppression or enhancement (
