No TI: s
992 Journal of Medicinal Chemistry, 1971, Vol. 14, S o . 10
brominative oxidation of the corresponding semicarbazorie, but resisted purification efforts. HYDRAZONIUVACETHYDRAZONISS The compounds were generall! p o d > w i t thlv ,i11(1 difficult to purify. The thiadinzolorie \\ a5 not obtniiictl analyticall> pure, but the structure I\ ;L\ confirmed b.r t h e exact ni:i+ of the parent i o n m c l :L ieawii:iblc fragmeiitatioii pattern in the 111~55yectruni
TABLE I11 5-NITRO-2-FC R A L D E H Y D E
+2"
1
2 3 4 5
Yield,
0
No.
NMe? NEti Pyrrolidino Piperidino Morpholino
% '
Crystn solvent
Alp,
Method
I3
9.5 30b 86 87 69
EtOH-1-120 95% E t O H Me011 E;tO€I EtO€I-H20
21i 184-1813
I3 I3 I
