3074
Vol. 51
L. R. RICHARDSON, C. E. WELCH AND S. CALVERT
TABLE I11 RESVLTS ON UNKNOWN MIXTURES Guaiacol carbonate found, 70
'.;
Alixturr
Composition,
1 2
Guaiacol carbonate, 3 1 ,5; sucrose, 0 . 5 ; starch, 68.0 Guaiacol carbonate, 5 1 . 5 ; sucrose, 9 5 ; acacia, 1 . O ; starch, 38.0 Guaiacol carbonate, 63 . 7 ;tragacanth, 0 . 3 ;starch, 3 6 . 0
3
29.38,30.64
49.16,49.76 D3.5, 63.89
A sample of commercial *;-grain guaiacol carbonate tablets was prepared by pulverizing twenty tablets, the average weight of each being 0.3865 g. or 3.R(i grains. Three-tenths gram samples were analyzed according to the method for mixtures, with the check results 75.53 and 75.3fi(r0. The average content, therefore, was 4.50 grains instead of the declared 5 grains.
Summary X new method for the estimation of guaiacol carbonate, depending on the conversion of guaiacol carbonate into a monobromo derivative, and a new compound, monobromo guaiacol carbonate, are described. Acknowledgement is made to I,. E. LVarren of the Food, Drug and Insecticide Administration for submitting the problem and furnishing the 'unknowns. " I
DEXVER,COLORADO [COXTRIBUTION FROM THE
DEPARTMENT
OF C€IE>fISTRl-, UNIVERSITY OF PIISSOUR1 ]
NEW DERIVATIVES OF CREATININE AND DIKETOPIPERAZINE'~' BY
L. R.RICHARDSOX AKD RECl$I\'SD 1 l h Y
C1,ACDE
2.5, 1929
I
