New Preparation of Benzylic Aluminum and Zinc Organometallics by

Nov 18, 2011 - Keith, J. C.; Tsao, D. H. H.; Sushkova, N.; Shaw, G. D.; Camphausen, ... Takahashi, T.; Baba, S.; Van Horn, D. E.; Okukado, N. J. Am. C...
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ORGANIC LETTERS

New Preparation of Benzylic Aluminum and Zinc Organometallics by Direct Insertion of Aluminum Powder

2011 Vol. 13, No. 24 6440–6443

Tobias D. Bl€ umke, Klaus Groll, Konstantin Karaghiosoff, and Paul Knochel* Department Chemie, Ludwig-Maximilians-Universit€ at, Butenandtstrasse, 5-13, 81377 M€ unchen, Germany [email protected] Received October 12, 2011

ABSTRACT

The reaction of commercial Al-powder (3 equiv) and InCl3 (15 mol %) with benzylic chlorides provides various functionalized benzylic aluminum sesquichlorides under mild conditions (THF, 20 °C, 324 h) without homocoupling (