Novel Deutero-Intermediates for Drug Discovery - C&EN Global

Publication Date: April 19, 2010. Copyright © 2010 AMERICAN CHEMICAL SOCIETY. ACS Chem. Eng. News Archives. First Page Image. Advertisements that ...
4 downloads 0 Views 247KB Size
񡑁񡑁񡑁񡑁񡑁 񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑂񡑃񡑄񡑅񡑆񡑇񡑄񡑈񡑉񡑄񡑐񡑂񡑑񡑒񡑓񡑉񡑄񡑐񡑔񡑄񡑕񡑖񡑗񡑉񡑄񡑘񡑆񡑙񡑂񡑐񡑆񡑇񡑐񡑈񡑠񡑆񡑇񡑖񡑘񡑡񡑂񡑃񡑄񡑐񡑢񡑆 񡑱( 񡑣

񡑁

񡑤񡑇񡑥

񡑱(

񡑁

񡑁

񡑤񡑇񡑥

񡑣,񡑨񡑩)񡑧񡑇

!񡑁񡑂񡑤񡑥񡑇 ∀#

񡑣񡑐

񡑁

񡑤񡑅

񡑤񡑅

񡑁

񡑨񡑩񡑩񡑰񡑇 񡑣񡑐

񡑨񡑩񡑩)񡑇

񡑁

񡑁

񡑤񡑇񡑥

񡑨񡑩∗񡑨񡑇

񡑤񡑁

񡑤񡑅

񡑁

񡑤񡑇񡑥

񡑤񡑦∀&񡑇

񡑇

񡑤񡑅 񡑤%񡑥

񡑁 񡑁

񡑤񡑅

񡑇

񡑨񡑩񡑨&񡑇

񡑇

񡑤񡑦+񡑩)

񡑇

񡑁

񡑇

񡑇

񡑣񡑐

񡑇

񡑁

񡑇񡑤񡑦񡑩񡑧

񡑣񡑐

񡑇

񡑇

񡑇

񡑁

񡑤񡑦񡑨∗񡑩񡑰񡑇

񡑁

񡑤񡑦∀񡑧񡑥񡑇

񡑁

񡑤񡑇񡑥 񡑱

񡑤񡑇 񡑥

񡑇

񡑣񡑐

񡑣񡑐

񡑤񡑇񡑥

񡑁 񡑰񡑩)∃񡑇

񡑰񡑩))񡑇

񡑤񡑦񡑰񡑩񡑇

񡑁

񡑁( 񡑧

񡑰񡑩∗񡑥񡑇

񡑁

񡑣񡑐

񡑤񡑦񡑰∗񡑇 񡑱񡑤񡑇 񡑥

񡑣񡑐 񡑁

񡑁

񡑱(

񡑤񡑇񡑥

񡑤񡑦񡑨񡑩񡑧񡑇

񡑣񡑐 񡑤񡑇񡑥

񡑤񡑇񡑥

񡑁

񡑤񡑦񡑨)񡑇

񡑤񡑦&∗񡑥񡑇

񡑤񡑇񡑥

񡑁

񡑨񡑩)񡑧񡑇

񡑣񡑐

񡑁

񡑤񡑦∀񡑧񡑨񡑇

񡑁

񡑤񡑇񡑥

񡑣񡑐

񡑇

񡑁( 񡑧 񡑤񡑇񡑥

񡑤񡑦񡑨񡑩∗񡑇

񡑨񡑩∗)񡑇

񡑣񡑐

񡑁

񡑁

񡑣񡑐

񡑇

񡑇 񡑇

񡑇

񡑤񡑇񡑥

񡑤񡑅

񡑨񡑩񡑨񡑩񡑇

񡑁

񡑁

񡑤񡑇񡑥񡑱

񡑇

񡑤񡑦񡑧񡑨񡑰񡑥񡑇

񡑁

񡑤񡑇񡑥

񡑁

񡑇 񡑇

񡑤񡑅

񡑁

񡑇 񡑤񡑅

񡑁

񡑁

񡑇

񡑣񡑐

񡑤񡑅

񡑨񡑩񡑰∀񡑇

񡑨񡑩񡑨񡑨񡑇 񡑤񡑅

񡑣񡑐 񡑁

񡑁

( 񡑧񡑁

񡑁

񡑤񡑇񡑥񡑱

񡑁

񡑁 񡑁

񡑤񡑇񡑥񡑱

񡑤񡑅

񡑨񡑩񡑥񡑧񡑇

񡑤񡑅

񡑤񡑅

񡑁 񡑁

񡑤񡑇񡑥

񡑤񡑅

񡑨񡑩񡑥∗񡑇

񡑇 񡑁

񡑤񡑇񡑥

񡑁( 񡑧

񡑨񡑩񡑧&񡑇

񡑁 񡑨񡑩񡑰∗񡑇

񡑁 񡑁

񡑤񡑇񡑥񡑱

񡑤񡑇񡑥 񡑁

∋񡑄񡑦

񡑁( 񡑧

񡑨񡑩񡑧񡑰񡑇

񡑁

񡑁

!񡑁񡑑񡑤񡑥񡑇∀#

񡑁

񡑤񡑅

񡑤񡑦+񡑩񡑰

񡑁

񡑤񡑇񡑥

񡑨񡑩񡑰񡑥񡑇

%

񡑁

񡑤񡑅

񡑁 񡑁

񡑤񡑇񡑥

񡑨񡑩)∀񡑇

񡑁 񡑁

∋񡑄񡑦

( 񡑧񡑁

񡑤񡑅

񡑁 񡑤񡑅

񡑁

񡑨񡑩)∗񡑇

񡑤񡑦񡑰񡑥񡑧񡑤 񡑇

񡑁

񡑁 񡑁

񡑤񡑇񡑥񡑱

񡑤񡑇񡑥

񡑁

񡑤񡑇񡑥

񡑨񡑩񡑩∃񡑇

񡑁 !񡑤񡑇 񡑥#(񡑁

񡑤񡑅

񡑤񡑅

񡑤񡑅

񡑤񡑇񡑥

񡑣񡑐

񡑁 񡑁

񡑤񡑇񡑥񡑱

񡑁

񡑤񡑇񡑥񡑱

񡑤񡑅

񡑣񡑐

񡑤񡑦񡑧񡑨񡑩񡑥񡑇

񡑁

񡑤񡑇񡑥

񡑁

񡑤񡑦񡑧񡑨񡑩񡑰񡑇

񡑤񡑅 񡑁

񡑁

񡑁

񡑁

񡑱񡑤񡑇񡑥

񡑱񡑤񡑇񡑥

񡑤񡑦񡑰∗)񡑇

񡑁

񡑤񡑦∃∀񡑩񡑇

񡑣񡑐

񡑤񡑦񡑨񡑰∃񡑇

񡑣񡑐 񡑤񡑇񡑥 񡑱

񡑤񡑇񡑥 񡑁

񡑁

񡑁

񡑣񡑐

񡑤񡑇񡑥

񡑁

񡑤񡑇񡑥

񡑁

񡑁

(񡑧 񡑁

񡑁

񡑣񡑐

񡑤񡑇񡑥

񡑁

񡑤񡑇񡑥

񡑤񡑦∃񡑩∃񡑇

(񡑱

񡑁

(񡑱

񡑱

񡑤񡑇񡑥

񡑤񡑇񡑥

񡑣񡑐

񡑰񡑩񡑥∃񡑇

񡑤񡑦񡑧∀∃񡑇 񡑤񡑇񡑥

񡑤񡑦))񡑇

񡑰񡑩񡑧񡑧񡑇

񡑰񡑩񡑥)񡑇

񡑱(

񡑤񡑇񡑥

񡑁( 񡑧

(񡑧 񡑁

񡑤񡑇񡑥 񡑁

񡑁

񡑤񡑇񡑥

񡑁

񡑰񡑩񡑨∀񡑇

񡑰񡑩)񡑰񡑇

񡑣񡑐

񡑤񡑇񡑥

񡑤񡑦∗∃񡑇

񡑤񡑇񡑥

񡑁

񡑤񡑦񡑧񡑧∃񡑇

񡑁

񡑁( 񡑧 񡑁

񡑧񡑩񡑩∀񡑇 񡑤񡑇񡑥 񡑁

񡑁񡑁񡑁񡑁 񡑁

񡑁

)񡑩񡑰񡑥񡑇

񡑁( 񡑧

񡑤񡑦񡑧∀∗񡑇

񡑤񡑇 񡑥񡑱

񡑁

񡑇

񡑁

񡑤񡑦񡑧񡑨񡑥񡑇 񡑇 񡑣񡑐

񡑤񡑇񡑥

񡑁

񡑇

񡑁

񡑇

񡑤񡑦񡑥񡑰)񡑇 񡑇

񡑁

񡑣񡑐

񡑁(񡑧

񡑦

񡑤񡑇񡑥

񡑤񡑦񡑧∗񡑩񡑇 񡑇

񡑁

񡑁 񡑁

񡑦

񡑧񡑩񡑩񡑥񡑇 񡑁

񡑁 񡑤񡑇񡑥

񡑣񡑐

񡑇

񡑁

񡑁

񡑤񡑇񡑥

񡑣񡑐

񡑣񡑐

񡑁

񡑁

񡑣񡑐

񡑤񡑇񡑥 񡑇񡑤񡑦񡑰񡑧񡑧 񡑤񡑇񡑥񡑱

񡑁 񡑁

񡑁

񡑤񡑇񡑥

񡑣񡑐

񡑤񡑦񡑧∀)񡑇

񡑤񡑇񡑥

񡑤񡑇񡑥

񡑤񡑇񡑥

񡑤񡑇񡑥

񡑤񡑦񡑰)∃񡑇 񡑤񡑇񡑥

񡑁 񡑦

񡑱񡑤񡑇񡑥

񡑦

񡑁

񡑦

񡑤񡑇񡑥

񡑣񡑐

񡑤񡑦񡑥񡑩񡑰񡑇

񡑣񡑐 񡑁

񡑁

񡑤񡑇񡑥

񡑰񡑩񡑥񡑨񡑇

񡑣񡑐 񡑦

񡑱񡑤񡑇񡑥

񡑁

񡑁( 񡑧

񡑰񡑩񡑥񡑥񡑇

񡑣񡑐 񡑦 񡑁

񡑁

񡑤񡑇񡑥

񡑰񡑩񡑥񡑧񡑇

񡑣񡑐 񡑁

񡑦

񡑁

񡑤񡑇񡑥

񡑰񡑩񡑨񡑥񡑇

񡑣񡑐 񡑁

񡑤񡑇񡑥

񡑁

񡑁( 񡑧

񡑣񡑐

񡑤񡑦)∀񡑇

񡑇񡑤񡑦񡑧∀∗ 񡑤񡑇񡑥

񡑁 񡑁 񡑤񡑦񡑰񡑧񡑧񡑇

񡑣񡑐

񡑇񡑤񡑦񡑧񡑩 񡑤񡑇񡑥

񡑁 񡑁 񡑥񡑩񡑩񡑨񡑇

񡑁(񡑧

񡑣񡑐

񡑁 񡑁 񡑥񡑩񡑰񡑧񡑇

񡑤񡑦񡑧∃∗񡑇

񡑱(

񡑤񡑦∗񡑩񡑰񡑇 񡑁

񡑁 񡑁 񡑥񡑩񡑰∗񡑇

񡑁!񡑤񡑇 񡑥#񡑧

񡑤񡑇񡑥񡑱

񡑁

񡑣񡑐

񡑤񡑦񡑰∀񡑩񡑇

񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑂񡑃񡑄񡑅񡑆񡑇񡑂񡑈񡑉񡑁񡑐񡑑񡑐񡑒񡑓񡑈񡑑񡑈񡑔񡑉񡑕񡑖񡑗񡑘񡑁񡑁񡑁񡑂񡑃񡑄񡑃񡑁񡑅񡑆񡑇񡑁񡑈񡑈񡑉񡑐񡑁񡑂񡑑񡑒񡑓񡑔񡑕񡑖񡑆񡑓񡑐񡑁񡑗񡑘񡑁񡑉񡑙񡑠񡑡񡑈񡑢񡑉񡑈񡑈񡑉񡑁 񡑂񡑣񡑆񡑓񡑕񡑤񡑁񡑁񡑥񡑉񡑦񡑢񡑠񡑙񡑧񡑢񡑥񡑠񡑉񡑉񡑁񡑁񡑆񡑑񡑁񡑁񡑙񡑉񡑉񡑢񡑥񡑠񡑦񡑢񡑦񡑧񡑦񡑨񡑁񡑁񡑁񡑁񡑁񡑁񡑩񡑰񡑇񡑤񡑁񡑁񡑁񡑥񡑉񡑦񡑢񡑠񡑙񡑧񡑢񡑥񡑠񡑧񡑉񡑁񡑁񡑆񡑑񡑁񡑁񡑙񡑉񡑉񡑢񡑥񡑠񡑦񡑢񡑱񡑦񡑧񡑦񡑁 񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁񡑁 񡑕!∀񡑒񡑖񡑕񡑤񡑁񡑁###񡑃񡑔񡑆∃!񡑒%񡑣񡑆∀񡑃񡑔񡑆∃񡑁

񡑁