Figure 1
current work
R
ONO2
one step, AgNO3-free; halide-free N
>95% yields
N
N previous work
1. R
NO3 N R
Hal
2. AgNO3
Scheme 1
Figure 2
1
NH2 1. Br NH2
2. N
H N
O
NCO , THF
A N
N
N
N
NH
, heat N
NH
3. MA, EtOH or H2O
O
O
N H
A
N
A N
N H
N N3
N
N
N H
O
CuI, Hunig's base, ACN
N3 A
N H
O HN
H N O
N
O
HN
A N
N
HN CuI, Hunig's base, ACN
Scheme 2
N
N N N
A N
H N
N
A A
N
O N
N
N
N H
N N
N H
Figure 3
2
