Environ. Sci. Technol. 2009, 43, 8652–8657
Nutritional Status and Gastrointestinal Microbes Affect Arsenic Bioaccessibility from Soils and Mine Tailings in the Simulator of the Human Intestinal Microbial Ecosystem B R I A N D . L A I R D , †,‡ J A C K Y Y E U N G , ‡ DEREK PEAK,‡ AND S T E V E N D . S I C I L I A N O * ,‡,§ Graduate Program of Toxicology, Department of Soil Science, and Toxicology Group, University of Saskatchewan, Saskatoon, SK, S7N 5A8
Received March 19, 2009. Revised manuscript received September 10, 2009. Accepted September 16, 2009.
In vitro gastrointestinal models, used to measure the metal(loid) bioaccessibility for site specific risk assessment, are typically operated under fasted conditions. We evaluated the hypothesis that fed conditions increase arsenic bioaccessibility on three reference soils (NIST 2711, NIST 2709, and BGS 102) and the bulk and
