ORGANIC CHEMICALS FOR CREATIVE SYNTHESIS - C&EN Global

Nov 6, 2010 - Advertisements that appeared within the print issues of Chem. Eng. News have been included in the C&EN Archives to provide a ...
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ORGANIC

CHEMICALS

FOR

CREATIVE

SYNTHESIS

When you check the chemical routes to a new compound—talk over t h e chemistry with Monsanto. You'll find Monsanto can provide you a variety of steppingstones — compounds t h a t are basic intermediates in eleven different fields of chemistry. Here is another new compound—a SUBSTI­ T U T E D A R O M A T I C , now available from Monsanto in semicommercial quantity:

«o

3,4-DICHLOROANILINE

NH2

CI

This highly reactive compound converts with good yields by reactions of the amino group as follows:

W i t h phosgene

CI < ^ ~~

With acylating agents

\

N = C= 0 (isocyanafes)

CI \^ CI

\

W i t h aldehydes

N = CHR (Schiff bases)

CI CI

y NHC-R (anilides) W i t h ethylene oxides and

W i t h sulfonyl chlorides

CH 2 CH 2 OH

°o CI