Organometallic high-pressure reactions. 2. Aldol reaction of silyl enol

Sampling of Transition States for Predicting Diastereoselectivity Using Automated Search Method—Aqueous Lanthanide-Catalyzed Mukaiyama Aldol Reactio...
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6963

J . Am. Chem. SOC.1983, 105, 6963-6965 Scheme la

Table I. Reactions of Carbanions with Complex 2 OCH,

CH

I

combined vield.b

3

4

70

75' 100 22 27 47 97' 67 >98' 0

25' 78 73 53 3c 33