Pharmaceuticals and related drugs - Analytical Chemistry (ACS

Pharmaceuticals and Related Drugs V . E. Papendick, 1. W . Sutherland, and D. E. Williamson Analytical Research Department, Abbott laboratories, North Chicago, 111.

T

covers analytical methods a n d topics related t o pharmaceutical analysis t h a t have appeared since t h e last review (2247) in this series and covers t h e literature t o J u n e HIS REVIEW

1968. T h e material has been arranged in t h e same tabular format t h a t was used in t h e earlier reviews. References t o t h e analysis of pharmaceuticals in biological media are denoted by a superscript B. These references include b o t h administered drugs and metabolites. Several general pharmaceutical reviews have been written (1624, 1772, 1953). Johnson has also reviewed t h e recent progress made in t h e pharmaceutical field (1009-1011). A revised edition of Wilson’s “Textbook of Organic, Medicinal, a n d Pharmaceutical Chemistry” has appeared (2473). Volume I V a of “Colorimetric Methods of Analysis” b y Snell and Snell has been published. It contains chapters on both amines and amides and includes many drugs (2194). While not directly involved with pharmaceutical analysis, a number of new books of a general nature have

been published which are of interest t o analytical chemists engaged in drug analysis. Two volumes of “The Chemistry of Open-Chain Organic Nitrogen Compounds” b y Smith have appeared (2118, 2119). Overberger, Anselme, and Lombardino have published t h e book “Organic Compounds with Nitrogen-KitrogenBonds” (1634).Sidgwick’s third edition of “The Organic Chemistry of Xitrogen” has also appeared (2080). T h e sixth edition of Veibel’s “The Identification of Organic Compounds, ” which contains both qualitative and quantitative methods of use to the pharmaceutical analyst, has been published (2371). An extensive list of books and periodicals dealing with drug analysis was compiled b y Rogavitz in a review on sources of information for drug analysis (1902). A book, “Methods of Vitamin Assay,” by Freed has appeared (634). T h e increasing use of thin layer chromatography in pharmaceutical analysis is reflected in t h e numerous reviews of t h e subject (377-379, 413, 2465). T h e documentation and preservation of thin layer chromatograms have been de-

Table 1.

Compound or class Alkaloidal amines Colchicine Ephedrine

Mescaline Methylephedrine Norephedrine Norpseudoephedrine Pseudoephedrine Spherophysine Alkaloids, general methods

scribed (6), and recent developments in thin layer chromatography surveyed (157). A comprehensive book by Justus Kirchener o n thin layer chromatography was published and contains both techniques and applications of T L C . It includes separate chapters on alkaloids, antibiotics, steroids, vitamins, and pharmaceutical products, as well as other chapters useful in drug analysis (1137).

Hemerich has reported on t h e recent advances in ion exchange chromatography (869), and its use in drug analysis and alkaloid separations has been reviewed (76). T h e value of gas chromatography in pharmaceutical analysis continues t o be reflected in t h e numerous reviews of t h e subject (284, 1008, 1568). McMartin and Street have studied t h e factors t h a t limit t h e sensitivity of columns used in t h e gas chromatography of drugs (1366). T h e application of spot tests for t h e identification of drugs has been reviewed (2294). T h e use of activation analysis t o determine the source of manufacture ( T e x t continued on page 196 R )

Alkaloids

Method or subject

References

Chromatographic, thin layer Phytobiological Review Chromatographic, gas Chromatographic, thin layer Colorimetric

(135, 819)

Extractive Identification Microcrystalloscopic Polarographic Review Spectrophotometric, ultraviolet Volumetric, acid-base Volumetric, conductometric Volumetric, coulometric VoIumetric, ox.-red. Chromatographic, paper; thin layer Identification Identification Identification Gravimetric Identification Review, characterization Chromatographic Chromatographic, adsorption Chromatographic, gas Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer

(RRl 1 (981

@ooj (600)

( 1 3 g B , 387, 951, 1996) (1660, 1979) (300, 639, 1084, 1145, 1856, 1508, 1691, 178gB) (433, 1195) (355, 433, 1758, 1908, 1911) (1798) (469)

r

(61 j

(1043) (493, 1196B,1425) (1506) (1566)

1668,

Colorimetric B.4nalyais of pharmaceuticals in biological media.

190 R

ANALYTICAL CHEMISTRY

(Continued)

Table 1. Compound or class

Alkaloids (Continued)

Method or subject

References

Countercurrent distribution Electrophoretic Extractive Fluorometric Gravimetric Identification

(999, 1239) (542) (89, 433, 1633, 1701, 2002, 2154, 2234) (2604) (2399) (433, 542, 609, 915, 1908, 2909, 2911, 2129, 2136, 2202, 2421) (1604) (1752) (114) (100) (423, 617, 1618, 1655) (1221, 1948) (923)

Mass spectrometric Microcrystallographic Official methods Oscillopolarographic Review Volumetric, acid-base Volumetric, amperometric Volumetric, complexometric Volumetric, coulometric Volumetric, ion pair X-Ray Alkaloids, miscellaneous Aconitine Aconitum Allosecurinine Aristolochic acid Catharanthus Condelphin Elatine Febrifugine Harmine Isofebrifugine Laudonine Mellictine Octine Phentanyl Pilocarpine

Quinazoline alkaloids Securinine Sparteine Indole group Ajmalicine Ajmaline Brevicolline 33r u cine

Ergot alkaloids

Ervatamia coronaria Indoles, general Lysergamide

Chromatographic, paper Chromatographic, thin layer Volumetric, amperometric Review Stability Chromatographic, thin layer Chromatographic, thin layer Colorimetric Colorimetric Spectrophotometric, ultraviolet Colorimetric Chromatographic, thin layer Electrophoretic Colorimetric Chromatographic, thin layer Extractive S ectrophotometric, ultraviolet dicrocharac terization Chromatographic, gas Chromatographic, paper Colorimetric Identification Optical rotation Spectrophotometric, infrared Stability Volumetric, coulometric Chromatographic, thin layer Colorimetric Microcrystallographic S ectrophotometric, ultraviolet IXentification Oscillopolarographic; stability

!%:!

1675) (1701) (1414)

(61, $92) (1675) (780) (69, 70) (1272, 1799)

(1908; 1911) (100)

Extractive; fluorometric Identification Spectrophotometric infrared Chromatographic, thin layer Colorimetric Countercurrent distribution Identification Polarographic Spectrophotometric Volumetric, am erometric Volumetric, couiometric

(2090) (252) (607) (131, 374) (1890, 2078, 6079, 2306) (999) (1908, 1909, 1911)

Chromatographic, column Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer

(905, 1029, 1394) (1809) (712, 905) (22, 905, 1029, 1187, 1717, 1809, 1810, 1900, 2314, 2464, 2541) (447, 712, 905, 1809, 2386, 2464) (22, 1186, 1187) (1189) (896) (1809, 1810) (632, 2284)

Colorimetric Electrophoretic Fluorometric Review Spectrophotometric, ultraviolet Stability Chromatographic, thin layer Chromatographic, gas Chromatographic, thin layer Chromatographic, gas Chromatographic, paper

g& (923)

(194, 1675)

(Continued)

VOL. 41, NO. 5, APRIL 1969

191 R

Table I. Compound or class Physostigmine

Rauwolfia alkaloids

Refractine Reserpine

Strychnine

Strychnos nuxvomica

Vellosine Vinca erecta Vinca rosea Yohimbine

Isoquinoline group Acetylcodeine Apomorphine Aquilegia formosa Berberine

Berberine derivatives Boldine Chelidonine Chelidonium majus Codamine Codeine

Method or subject

References

Chromatographic, thin layer Identification Chromatographic, thin layer Colorimetric Electrophoretic Identification Spectrophotometric, ultraviolet Volumetric, acid-base Chromatographic, thin layer Fluorometric Oscillopolarographic S ectrophotometric, ultraviolet &lumetric, acid-base Volumetric, dye transfer Chromatographic, thin layer Chromatographic, thin layer Colorimetric Fluorometric Oscillopolarographic Review Spectrophotometric, ultraviolet Stability Chromatographic, column Chromatographic, paper Chromatographic, thin layer Colorimetric Countercurrent distribution Dosage estimation Electrophoretic Extractive Identification S ectrophotometric, ultraviolet dlumetric, acid-base Volumetric, conductometric Volumetric, coulometric Volumetric, oscillometric Chromatographic, thin layer Colorimetric Extractive Volumetric, dye transfer Chromatographic, thin layer Chromatographic, thin layer Cytostatic activity Colorimetric Identification Volumetric. coulometric

(177, 401, 4.50, 696, 1828) (1336, 1409)

Chromatographic, thin layer Chromatographic, paper Identification Chromatographic, thin layer Chromatographic, paper Colorimetric Gravimetric Identification S ectrophotometric, ultraviolet dermogravimetric, complex salts Volumetric, amperometric Identification Colorimetric Chromatographic, thin layer Colorimetric Chromatographic, paper Chromatographic, thin layer Colorimetric Identification Chromatographic, adsorption Chromatographic, column Chromatographic, gas Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Colorimetric Extractive Gravimetric Identification Mass spectrometric Microcrystallographic Spectrophotometric, ultraviolet Stability

BAnalysia of pharmaceuticalsin biological media.

192 R

0



(166)

(1916)

(64.9)

(84, 1908, 1911) (1465) (8232) (431, 1037, 2603) (1936, 2286, 2603) (1662) (2056) (705) (1701)

1716, 8103)

1911, 8189)

(44)

(8487)

(194, 1676) ($338) (376. 1398)

(1534, 8390) (9244) (2129)

(2110)

(1408, 1682, 2011B) (197, 307, 1498, 1669) (1374, 1386, 2844) (569,924,1416, 1762, 1862, 2160, 2390) (1500, 1979, 2110) (9002, 2234)

!&b, 1909,1911,1129) (2625)

(2397) (1363, 1476, 1492) (989)

Table 1. Compound or class Codeine derivatives Corydalis alkaloids Dehydrocorydalmine Diacetylmorphine

Dihydrocodeine Dihydrocodeinone

Dihydromorphinone Ethylmorphine Ethylpapaverine Galanthamine Galanthus krasnovii Galanthus nivalis Glaucine Hydrastine Hydrastinine Isopyrum thalictroides Leucojum aestivum Lophophora williamsii Magnoflorine Methylpavine Meth lporphyroxine Morpiine

Morphine derivatives

Nalorphine Narceine

Narcotine


Method or subject Volumetric, acid-base Volumetric, coulometric 0 tical rotatory dispersion Cgromatographic, gas; thin layer Identification Chromatographic, gss Chromatographic, paper Chromatographic, thin layer Identification Microcrystallographic Chromatographic, thin layer Mass spectrometric Chromatographic, column Chromatographic, thin layer Identification Microcrystalloscopic Official method Chromatographic, thin layer Chromatographic, paper Chromatographic, thin layer Identification Colorimetric S ectrophotometric ultraviolet &romatographjc, thin layer Chromatographic, paper; thin layer Chromatographic, paper Colorimetric Review, methods Chromatographict pa er Countercurrent distrifmtion Chromatographic, paper Fluorometric Chromatographic, thin layer Chromatographic, paper Chromatographic, thin layer Chromatographic, column Chromatographic, thin layer Stability Identification Chromatographic, column Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Electrophoretic Extractive Gravimetric Identification Mass spectrometric Microcrystallosco ic Optical rotatory fkpersion Oscillopolarographic Review, methods Spectrophotometric, infrared Stability Volumetric, amperometric Volumetric, conductometric Volumetric, coulometric Volumetric, ox.-red. Chromatographic, column Chromatographic, ion exchange Colorimetric Electrophoretic Extractive Identification Spectrophotometric, ultraviolet Volumetric, acid-base Chromatographic, paper Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Colorimetric Identification Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer

References

(986) (612) (1622) [%f)l762,

(2129) (2397) (924) (2226) (616, 1294)

239043991)

117821

(669,9,94, 1786) (1908, 1909, 1911)

(1)

[$% (1408, 16'22, 2629B) (277, ~ 4 , ~ O 6 6 , 2 2 4 4 ) (669, 924, 1074, 1666, 1669,1762 8160, 2390-2392B, 6629B, 263d3) (1300,1623,2049, 262gB)

I;%)

(1601, 1636, 1667)

(1866, 1908, 1911, 6421, 6640)

(2226) (2397) (169) (100)

(1892) (1288) (100, 341, 1818, 1819) (2373) (2487) (194) (372) (617)

{%{

(1816)

1669, 1762,

Colorimetric Extractive Fluorometric Identification BAnalysia of pharmaceuticals in biological media.

(Continued) VOL. 41, NO. 5, APRIL 1969

0

193 R

Table 1. Compound or class Neopine Opium

Opium alkaloids

Pan ano1ine Papaver genus Papaverine

Papaver rhoeas Stepharanine Thebaine

Isoquinoline, bis-benzyl group Emetine

Ipecacuanha alkaloids Tubocurarine

Pyridine group Lobeline Lobinaline Nicotine Nornicotine Quinoline group Cinchona alkaloids

Cinchonine

Cinchoninic acid Echinorine Haplophyllum alkaloids


Method or subject Volumetric, amperometric Volumetric, oscillometric Volumetric, acid-base Chromatographic, column Chromatographic, thin layer Determination of water in Microcharac terization Neutron activation analysis Chromatographic, gas Chromatographic, gel Chromatographic, ion exchange Chronlatographic, paper Chromatographic, thin layer

(1415, 1113) (131, 1037, 1616) (164) 1957. 958) (1283) ' (2190) (889) (307) (2176, 2244) (569, 924, 1037, 1074, 1300, 1669, 1762, 2150, 2390) (2215) (1134) (1727) (1235, 1727) (1726) 11242, 1670. $ 2 ~ 6 ) (472, 569, 575, 984, 1669, 1762, 2103, 2150, 2390) (300, 2138)

Mass spectrometric Review, methods Identification Chromatographic, column Review Chromatographic, paper Chromatographic, thin layer colorimetric Electrophoretic Fluorometer Gravimetric Identification Mass spectrometric Oscillopolarographic Spectrophotometric, ultraviolet Stability Sustained release Volumetric, acid-base Volumetric, coulometric Volumetric, ox.-red. Chromatographic, column Chromatographic, paper Chromatographic, thin layer Identification Chromatographic, ion exchange Chromatographic, thin layer Colorimetric Extractive Mass spectrometric Stability

(AM\

i8i04)

(2137, 2138) (1908, 1909, 1911, 2129, 2203) i2225) il00,

(472; 791, 934, 1465, 1474, 1739, 2076) (100, 1681) (1807)

(300, 340, 383, 520) ( 1675) (789)

(7%)

Chromatographic, thin layer Colorimetric Extractive Fluorometric Identification Chromatography, thin layer Extractive Chromatographic, paper Chromatographic, thin layer Extractive Volumetric, acid-base

(433,'1908,1909, 1911) (714, 1074, 1416) (1284, 2315) (1633) (2315) (8234) (74)

Chromatographic, thin layer Colorimetric Stability Mass spectrometric Chromatographic, thin layer Extractive Chromatographic, thin layer Chromatographic, column Chromatographic, thin layer Extractive Microsublimation Extractive Gravimetric Identification Mass spectrometric Volumetric, acid-base Colorimetric Volumetric, amperometric Chromatographic, column; thin layer Colorimetric Chromatographic, thin layer Polarographic

2186)

(1633)

(1091)

(44)

(2137)

(1716) (1604)

(44)

(Continued) ~~

194 R


~~~~

~~

~

Table 1. Compound or class Quinidine

Quinine

Quinocide Pyrrolizidine group General

Platyphylline Steroidal group Condelphine Conissine Delphinium elatum Elatine Kurchi alkaloids Solanaceae alkaloids Solasodine Tomatidine Veratrum alkaloids Tropane group Atropine

Belladonna alkaloids

Cocaine

Datura quercifolia Homatropine

Hyoscyamine


Method or subject

References

Chromatographic, paper Chromatographic, thin layer Colorimetric Stability Volumetric, coulometric Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Electrophoretic Extractive Fluorometric Identification Spectrophotometric, ultraviolet Stability Volumetric, acid-base Volumetric, amperometric Volumetric, coulometric Identification

(1685, 171.4) (1686, 2187) (466) (2187) (368) (1221 ) (1380, 1670) (1713) (642) (433) (299, 1803) (433, 1762, 1909) (1803) '

(13801

Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Review Electrophoretic Spectrophotometric, ultraviolet Microcrystallographic Chromatographic, paper Colorimetric Chromatographic, thin layer Chromatographic, column Chromatographic, column Volumetric, acid-base Colorimetric Official methods, comparison Review Chromatographic, thin layer; gravimetric Chromatographic, thin layer; gravimetric Chromatographic, thin layer Extraction; volumetric, acid-base Chromatographic, column Chromatographic, paper Chromatographic, thin layer Colorimetric Electrophoretic Extractive Identification Stability Sustained release Volumetric, acid-base Volumetric, conductiometric Volumetric, coulometric Volumetric, ox.-red. Volumetric, precipitation Chromatographic, column chromatographic, paper Chromatographic, thin layer Colorimetric Extractive Official methods Spectrophotometric Stability Volumetric, acid-base Volumetric, amperometric Chromatographic, paper Chromatographic, thin layer Extractive Identification Microcrystallographic Volumetric, acid-base Chromatographic, pa er Chromatographic, coEmn Chromatographic, paper Chromatographic, thin layer Identification Volumetric, acid-base Chromatographic, column Chromatographic, thin layer

(895)' (1802)

( 1029, 1636, 2496) (661, 1172, 1642, 2214) (16, 1.31. 812. 1029. 1666. 2103) (16; 845; 1916, 2431, 6495) (5L2) (1?76, 2234, 2431) (433, 1866, 1908, 1909, 1911) (15, 470, 1857) (1807) (1636, 1794)

(1702) (259,'1415) (259, 1415) (6069) (472, 657, 1415, 1757, 2161) 21 (859, 667, 1341) (659, 1767) (1757, 2017, 2151) (472) (1.341) (1757) (922) \-

($61)

(1566) (1776. 223L) (1908; 1909; 1911) (8397) (1794) (1172) (812) ($61) (1566) ( 1908) (1794)

(756, 1029, 24.95) (1029, 1082, 1952)


195 R

Table 1. Compound or class

Methylhomatropine Scopolamine

Stramonium alkaloids Tropane derivatives Tropane, general Tropine Xanthine group Caffeine

Evoxanthine Theobromine

Theophylline

Xanthine derivatives


Method or subject

References

Colorimetric Stability Volumetric, acid-base Chromatographic, thin layer Volumetric, acid-base Chromatographic, column Chromatographic, paper Chromatographic, thin layer Colorimetric Electrophoretic Identification Stability Volumetric, amperometric Chromatographic, thin layer Identification Chromatographic, paper Chromatographic; thin layer Volumetric, acid-base Chromatographic, thin layer

(131j (1794) (131, 8816)

Chromatographic, column Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Extractive Gravimetric Microcrystallographic Refractometric Review Spectrophotometric, infrared Spectrophotometric, ultraviolet Volumetric, acid-base Volumetric, amperometric Volumetric, ox.-red. Chromatographic, thin layer Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Identification Spectrophotometric, ultraviolet Volumetric, acid-base Volumetric, amperometric Volumetric, ox.-red. Chromatographic, gas Chromatographic, thin layer Identification Spectrophotometric, ultraviolet Stability Volumetric, acid-base Volumetric, amperometric Volumetric, conductometric Volumetric, ox.-red. Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Electrophoretic Nuclear magnetic resonance Spectrophotometric, ultraviolet Volumetric, ox.-red.

1803)

i188k’,

(io%:

2204) (466, 1399)

BAnalysis of pharmaceuticals in biological media.

of drugs was presented (2008). T h e

ysis were investigated by Mesnard

separation and identification of hallucinogens b y thin layer chromatography, ultraviolet, and infrared spectrometry have been described. Specific methods were given for LSD, DMT (N,N-dimethyltryptamine) , a n d psilocybin (1410). Bellman has reported on a general method for mass spectral identification of hallucinogens (145). Elucidation of t h e structure of alkaloids b y mass spectrometry has also been described (783). T h e condensation of 2thiobarbituric acid with aldehydes and its application t o pharmaceutical anal-

(1448).

196

R


Two books have been published which present t h e basic principles, techniques, and instrumentation of titrations in nonaqueous solvents (821, 930). This subject has also been reviewed b y Ciampa and coworkers (390). Nonaqueous titrations, acid-dye methods, gas chromatography, and thin layer chromatography were among t h e subjects included in a survey b y Papariello and Tishler o n t h e classification, separation, and general methods of analysis of alkaloids (1651). T h e application,

theory, a n d basic instrumentation of high frequency titrations in drug analysis have been reviewed b y Kalinowski (1064). T h e analysis of multiple component drug mixtures b y coulometric methods has also been surveyed (1057). A literature review of ultraviolet spectrophotometry and its application in pharmacy has been made for 1963 through J u n e 1966 (1210). Bubon has reviewed t h e history, theory, and applications of flame photometry in pharmaceutical analysis (301). T h e use of

(Tezt continued on page 880 R )

Compound or class Actimycin Actinoidin

Actinomycin Albocyoline Amphotericin

Ampicillin Aureofungin Azolomycin Bacitracin Bruneomycin Capreomycin Cephaloridine

Cerulenin Chloramphenicol

Chlortetracycline

Chromomycin Cloxacillin Cyclacidin Cyclamy cin Cycloserine Daunomycin Dequalin Doxycycline Edeine Erythromycin

Table II. Antibiotics hlethod or subject Chromatographic, thin layer Fluorometric Chromatographic, paper Colorimetric Diffusion coefficient Spectrophotometric, ultraviolet Spectrophotometric, visible Identification Chromatographic Colorimetric Identification Stability Colorimetric Microbiological Agar diffusion Nuclear magnetic resonance Turbidimetric Stability Chromotographic, thin layer Stability Identification Review Chromatographic, thin layer Identification Polarographic Stability Volumetric, ox.-red. Identification Calorimetric Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Identification Microbiological Polarographic Radiometric Spectrophotometric Spectrophotometric, ultraviolet Spectrophotometric, X-ray Stability Turbidimetric Volumetric, argentometric Volumetric, ox.-red. Chromatographic, column Chromatographic, thin layer Extractive Polarographic Review, methods Spectrophotometric Stability Volumetric, acid-base Volumetric, argentometric Identification Microbiological Identification Identification Stability Volumetric, complexometric Identification Microbiological Specifications Chromatographic, paper Chromatographic, thin layer Chromatographic, column Chromatographic, thin layer Electrophoretic Spectrophotometric, ultraviolet Stability Volumetric, acid-base Volumetric, complexometric

References (8039) ($039) (2166) (8166) (693)

($10 ) (1036) (1588)

(788)' (487,1640,8033) (1868,1864) (1941,1993) (8033) (2148) (364,1397) (80)

(79:1117,1676) (1118) (1663,1664 (8185) (80. 1663) (1676,16k1,1663,1664) (659,1118) @1&)

(391,1089) (1561) (2869) (104) (596) (84.6) (846) (109) (109,11.46,1193,1689) (1193) (911,1868) (1689,8076, 8434)

((8%)

(Continued)

VOL. 41, NO. 5, APRIL 1969

rn

197 R

Table II. Antibiotics (Continued) Compound or class

Method or subject

References

Furacillin General

Polarographic Chromatographic, thin layer Identification Microbiological Polarographic Review Spectrophotometric, infrared Spectrophotometric, ultraviolet Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Microbiological Chromatographic Chromatographic, gas Chromatographic, thin layer Colorimetric Fluorometric Particle size distribution Volumetric, ox.-red. Identification Chromatographic, ion exchange Diffusion coefficient Identification Colorimetric

(1572) (8111

Gentamycin

Griseofulvin

Hamycin Kanamycin Levomy cetin Lincomycin Metamycin Methicillin

Mitramycin Monomycin Morellin Mutomycin Neomycin

Neotolomycin Nisin Nojirimycin Novobiocin Nystatin

Oleandomycin Olivomycin Oxacillin

Oxytetracycline

Chromatographic, gas Colorimetric Colorimetric Spectrophotometric, ultraviolet Chromatographic, thin layer Distribution coefficient Microbiological Stability Volumetric ox.-red. Identification Diffusion coefficient Identification Review, methods Identification Chromatographic, column Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Colorimetric Electrophoretic Identification Microbiological Spectrophotometric Stability Identification Agar diffusion Identification Agar diffusion Stability Volumetric, complexometric Chromatographic Colorimetric Identification Spectrophotometric, infrared Stability Colorimetric Countercurrent distribution Identification Identification Chromatographic, thin-layer Distribution coefficient Spectrophotometric, infrared Spectrophotometric, ultraviolet Stability Chromatographic, thin layer Colorimetric


198 R


(1369) (1369) (1369) (2427) (521) (964)

(2378)

(793) (1079) (1901) (628, 1377) (1713. 2385) (248, 902, 1706) (2658) (1706, 1901) (1745) ( 1079) ( 1993, 2531 ) (2086)

(117)

(979)

(521 1521. 15961 (521j (229) (1260, 1330, 1993) (1597) (1897) (1529)

(1117, 1575)

(577)

(Continued)

Table II. Compound or class

Paromomycin

Penicillins

Polymyxin Propicillin Quinomycin Rifamycin Ristomycin Rovamy cin Rubidomycin Streptomycin

Streptonigrin Streptoxotocin Tetracycline

Antibiotics (Continued)

Method or subject Polarographic Review, methods Spectrophotometric Stability Volumetric, acid-base Chromatographic, ion exchange Colorimetric Identification Spectrophotometric, ultraviolet Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Colorimetric Extractive Identification Microbiological Polarographic Spectrophotometric Spectrophotometric, infrared Spectrophotometric, ultraviolet Stability Volumetric, amperometric Volumetric, complexometric Volumetric, coulometric Volumetric, mecurometric Volumetric, ox.-red. Chromatographic, thin layer Stability Enzymatic Chromatographic, thin layer Review, method Spectrophotometric, visible Stability Colorimetric Diffusion coefficient Polarimetric Stability Identification Biological Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Colorimetric Fluorometric Identification Polarographic Spectrophotometric Stability Volumetric, complexometric Identification Colorimetric Chromatographic, column Chromatographic, gel filtration Chromatographic, paper Chromatographic, thin layer Colorimetric Countercurrent, distribution Identification Microbiological Polarographic Review Review, method Spectrophotometric Spectrophotometric, infrared Spectrophotometric, ultraviolet Spectrophotometric, X-ray Stability

Trichomycin Tylosin Tyrothricin Vancomycin

References (1663)

(2185) ( I 663) (1575, 1663) (559) (1901) (681)

(935, 1901) (6211 (440)

{??: &, 1361, 174.3, 1945, 2351) (233)

(2094) (381, 729, 2457) (1216, 1486, 1942, 2094) (525, 526, 2458) (1990) (900) (1020) (441, 471, 526, 1020, 1177, 1483, 1561, 1642, 2197, 2531) (234, 758B) (1561) (1065) (1769, 2500) (505, 2020, 2565) (917 , 953) (1487) (2566) (2071)

(1995) (2269) (975) (544, 2536) (29, 865) (1097, 1146) (29, 122, 2027) (590) (381) (2468) (I991) (1561) (1561) (275) (623)

ir75, (98, 595, 628) (79, 466, 1116, 1117, 1146, 1576, 1743, 1945, 2095) (1755)

1663,

Volumetric, acid-base Identification Spectrophotometric, X-ray Stability Microbiological Colorimetric

BAnalyais of pharmaceuticals in biological media.

VOL. 41, NO. 5, APRIL 1969

199

R

Table 111.

Inorganic and Metal-Organic Compounds

Compound or class

Method or subject

References

Aluminum

Colorimetric Neutron activation analysis Review, methods Volumetric, complexometric

( g ~976,1101, , 1194,

(23r2) 2022, 2496)

Ammonium salts Antimony Arsenic Arsenic, organic Bismuth

Boric acid

Bromides

Bromine, organic Calcium

Colorimetric Chromatographic, thin layer Chromatographic, thin layer Neutron activation analysis Radiometric Volumetric, ox.-red. Colorimetric Gravimetric Incompatibility with tetracycline Polarographic Volumetric, complexometric Colorimetric Polarographic Volumetric, acid-base X-Ray diffraction Gravimetric Neutron activation analysis Radiometric Volumetric, precipitation Volumetric, ox.-red Volumetric, precipitation Spectrophotometric, flame Volumetric, complexometric

m r , i6r8,

(495, 657, 2463) (1402) (2307) (671)' (244, 518, 1402, 1498, 2021)

(8003)

(959, 1880) (3556) (1889, 1 4 l S , 2416) (1 (844, 765)410, 518, 1132, 1144, 1184, 1256, 21 05B, 21 58)

Chlorides Chlorine, organic Chromate Cobalt Copper Fluorides Fluorine, organic General

Heavy metals Hydrogen cyanide Iodides

Iodine Iodine, organic

Iron

Lead

Volumetric, precipitation Radiometric Volumetric, precipitation Chromatographic, thin layer Radiometric Identification Neutron activation analysis Spectrophotometric, ultraviolet Volumetric, complexometric Colorimetric Diffusion, distillation Volumetric, precipitation Colorimetric Atomic absorption Chromatographic, paper Chromatographic, thin layer Polarographic Identification Incompatibility with penicillin Colorimetric Chromatographic, thin layer Electrophoretic Radiometric Volumetric, precipitation Radiometric Stability Identification Neutron activation analysis Radiometric Volumetric, ox.-red. Volumetric, precipitation Chromatographic, paper Identification Radiometric Volumetric, complexometric Volumetric, ox.-red. Atomic absorption Neutron activation analysis Review, methods Volumetric, ox.-red. X-Ray emission


200 R


(1880)

(2003, 2036) (2413, 2415) (315) (849E,1530) (2160)

(956, 1180) (116, 1510)

(Continued)

Table 111.

Inorganic and Metal-Organic Compounds (Continued]

Compound or class

Method or subject

References

Magnesium

S ectrographic, flame vp olumetric, complexometric

(1765) ( 2 4 , 518, 1982, 2158, 2.496)

Manganese Mercury

Polarographic Amperometric Colorimetric Identification Volumetric, complexometric X-Ray diffraction Colorimetric Polarographic Radiometric Review Spectrophotometric, ultraviolet Identification Colorimetric Volumetric, ox.-red. Kj eldahl Chromatographic, gas Colorimetric Identification Chromatograph, ion exchange; thin layer Polarographic Complexometric; gravimetric; spectrophotometric, flame Volumetric, precipitation Review, combustion method Gravimetric Volumetric, ox.-red. X-Ray Emission Gravimetric Neutron activation analysis Potentiometric Spectrophotometric, flame Gravimetric Colorimetric, identification Volumetric, ox.-red. X-Ray diffraction Colorimetric Radiometric Volumetric, precipitation Chromatographic,thin layer Colorimetric Polarographic Volumetric, complexometric Chromatographic, gas Conductiometric Neutron thermalization Radiometric Review Volumetric, ox.-red. Colorimetric Gravimetric Volumetric, complexometric X-Ray diffraction

Mercury, organic

Nickel Nitrites Nitrogen, organic Nitrogen oxides Phosphamides Phosphates Polyphosphates Potassium Selenium, organic Silicates Silver Sodium

Sulfates Sulfide, sulfite, thiosulfates Sulfur Sulfur dioxide Sulfur, organic Tin Tungsten Water

Zinc

Table IV. Compound or class Acridines

Amides

(1920)

(1261) (1153)

(2036) (755, 2413, 2415)

($447) (1412) (858) (1696) (6220) (1006, 2276) (164, 699, 2121) (2370) (655) ( 2 4 , 654, 977, 1294, 2022, 2344) (124.9)

Nitrogen-Containing Compounds

Method or subject Chromatographic, paper Chromatographic, thin layer Colorimetric Fluorometric Spectrophotometric, ultraviolet Stability Volumetric, conductometric Volumetric, oscillometric Volumetric, ox.-red. Volumetric, precipitation Chromatographic, column Chromatographic, gas

References

(1296)

(1151, 1602)


201

R

~

Table IV. Compound or class

Nitrogen-Containing Compounds (Continued)

Method or subject

References

Chromatographic, paper Chromatographic, thin layer Collaborative Colorimetric Crystallographic Identification Polarographic Review Spectrophotometric, infrared Spectrophotometric, ultraviolet Stability Volumetric, acid-base Volumetric, coulometric Volumetric, ox.-red. Volumetric, precipitation Amines Alicyclic amines

Aliphatic amines

Aminosalicylic acids

Antihistamines

Aromatic amines

Nitrogenous organic bases

Phenylalkylamines

Procaine and analogs

Gravimetric Identification Volumetric, acid-base Volumetric, complexometric Volumetric, ox.-red. Chromatographic, column Chromatographic, gas Chromatographic, thin layer Colorimetric Gravimetric Identification Polarographic Spectrophotometric, infrared Spectrophotometric, ultraviolet Stability Volumetric, acid-base Chromatographic, thin layer Colorimetric Identification Spectrophotometric, ultraviolet Spectrometric, mass Volumetric, acid-base Volumetric, ox.-red. Chromatographic, column Chromatographic, gas Chromatographic, ion exchange Chromatographic, thin layer Colorimetric Crystallographic, identification Extractive, ion pair Review Spectrophotometric, dtraviolet Volumetric, acid-base Volumetric, conductometric Chromatographic, thin layer Colorimetric Identification Nuclear magnetic resonance Spectrophotometric, ultraviolet Chromatographic, gas Chromatographic, partition Chromatographic, thin layer Colorimetric Extractive, ion pair Identification Refractometric Spectrophotometric, infrared Spectrophotometric, ion pair Volumetric, acid-base Volumetric, complexometric Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Countercurrent distribution Identification Polarographic Review Spectrophotometric, ultraviolet Volumetric, acid-base Chromatographic, gas Chromatographic, paper

BAnaiysis of pharmaceuticals in biological media.

202

R


(382, 519, 950, 951, 1573, 1584, 17.41,

2335, 2562) (1755) (956, 1755) (452. 483, 2047) (2046) (146, 1108, 1607, 1612, 1613, 1614) (L27. 1296. 1,427) (i427, 1481, is8k.j (519, 1197, 1275,1276, 1280, 1795, 2475, 2561) (1059) (255, roo, 1058, i z r 7 , 2200,2480, 2561)

'B,1710, 2318)

1928, 2082, 2110)

(1998) (186, 1105) 1387, 516) (1698, 2297) (799. 1270) (516 ) (28, 609, 781) 1587)

(214, 2,420j

1547)

12018 )

1965)

(Continued)


Sympathomimetic amines

Amino acids

Nitrogen-Containing Compounds (Confinued)

Method or subject

References

Chromatographic, partition Chromatographic, thin layer Colorimetric

(1.916)

Crystallographic Identification Polarographic Review Spectrophotometric, ultraviolet Stability Volumetric, acid-base Volumetric. conductometric Volumetric; ox.-red. Chromatographic, gas Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Identification Polarimetric Spectrophotometric, infrared Stability Automatic analysis Chromatographic, gas Chromatographic, gel Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Coagulation Colorimetric

Amino alcohols Amino esters

Amino ethers

Amino phenols

Electrophoretic Enzymatic General methods Identification Ionization constants Neutron activation Polarimetric Polarographic Radiometric Specifications Spectrophotometric, infrared Spectrophotometric, ultraviolet Stability Thrombin inactivation test Volumetric, acid-base Volumetric, complexometric Volumetric, coulometric Volumetric, ox.-red. Chromatographic, gas Chromatographic, thin layer Colorimetric Chromatographic, paper Chromatographic, thm layer Spectrophotometric, ultraviolet Stability Chromatographic, gas Chromatographic, paper Chromatographic, partition Chromatographic, thin layer Colorimetric Extractive, ion pair Identification Nuclear magnetic resonance Polarographic Review Spectrophotometric, infrared Spectrophotometric, ultraviolet Stability Am erometric BioPogical Chromatographic, column Chromatographic, gas Chromatographic, ion exchange Chromatographic, paper


(168, 643, 1198, 1869) (168, 420, 836, 1921, 2041) (2132) (620, 643, 832, 1869)

(1241,1679) (16%

(505, 1484) (3.97, 664) (386)

(1416=, 1692, l'728B)


0

203 R



Method or subject

References


(1296, 8460) (388, 866, 1136) (837, 838, %.@,831, 1867, 1416, 1418, 1698, 1868, 2890) (614, 1,996) (614, 1417B, 1419) (1021) (1140, 1141) (486) (388, 694, 1498, 1493, 1776) (90, 646, 1140, 1141, 13&, 1986) (2467) (2089 8389) ( 17&) (8089) ( I 370)

Extractive, ion pair Fluorometric Identification Polarimetric Polarographic Spectrophotometric, ultraviolet Stability Volumetric, coulometric Chromatographic, thin layer Colorimetric Volumetric, acid-base Colorimetric

Azepines A!40

Barbiturates

Amperometric Chromatographic, gas Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Colorimetric Crystallographic Differential scanning calorimetry Differential thermal analysis Extractive Fluorometric Identification Nuclear magnetic resonance Polarographic Review Specifications Spectrophotometric, infrared Spectrophotometric, ultraviolet

Benzimidazoles Benzodiazepines

Carbamates

Diazo Dibenzazepinea Guanidines

Spectrometric, mass Stability Volumetric, acid-base Volumetric, com lexornetric Volumetric, contuctometric Volumetric, ox.-red. Volumetric, precipitation Spectrophotometric, ultraviolet Stability Volumetric, acid-base Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Gravimetric Identification Polarographic Spectrophotometric, ultraviolet Stability Volumetric, acid-base Chromatographic, gas Chromatographic, thin layer Colorimetric Identification Nuclear magnetic resonance Refractometric Specifications S ectrophotometric, ultraviolet A h m e t r i c , acid-base Volumetric, ox.-red. Colorimetric Volumetric, ox.-red. Chromatographic, paper Chromatographic, thin layer Colorimetric Gravimetric Identification Stability Volumetric, complexometric

BAnalyaia of pharmaceuticale in biological media.

204 R


(160, 2482)

664, 788, 993, 10705, 1106, 1367B, 1677, 8164) ( 12LGB) (164, 8126) (@,630,631, 726, 926, 9 B B , 103.48, 1236, 1600, 1601, 1978, 21 61B, 8864, 2318, 8618, 8643-9646) (1060, 1788, 1786, 1841, 8019) (1805) (1876) (12321) (68rB 1677, 1788-1 786, 8166B) (2038s) (871, 68rB, 891, lO3dB, 1149B, 9019, 2613, 2646) (1931, 1932) (688, 2638) (44 1401, 1@7) (106)

(726, 787, 1696) (163, 190, 933, 934, 1606, $069, 9166B, 2259, 8394B, %613)

(.@a)

(2367, 2488) (520, 631, 633, 666, 1515-1316, 1779) (971, 8286) (8033) (1779, 2086,8482) (1068)

(992) (998) (872) (2087”) (949) (1061, 1806B) (874, 1081, 1886B) (107) (1967) (892, 1699, 1600) (367, 2088B) (367, 1973) (107, 169)

(2310) (1061)

(892) (14.@)

(2016) (809, 21 71, $470, 2646) (71, 736, 766) (766, 768) (809, 8646) ( 736) (1497)

(Continued)

Table IV.


Compound or claw

Method or subject

References

Hydantoins

Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Identification Microbiolo 'cal Polarograpfic S ectrophotometric, ultraviolet olumetric, complexometric Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Colorimetric

(8or.4) (408j '

(1468B, 1680, 8664) (41bB,8664) (708, 8664) (1O1cjB) 11016B)

vp

Hydrazides

Hydrazines

Imidazoles

Imidazolidines Imidazolines

Imides

Indoles

Indolineones

Morpholines

Naphthyridines Nitro

Nucleosides

(680,1064, 17lBB) (1683) (34,1674, 2144) (87, 34, 648, 666,863B, 97SB, 1064, 1.403. 1683. 8836.8837) (196%)' (368, $69) (36,868, 690, 1173, 8308) (2~ior) (2241) (1064, 1683, 814.4) (1966) ( 196, 8146)

Dissociation constants Gmometric Polarographic Review Specifications Stability Volumetric, acid-base Volumetric, complexometric Volumetric, coulometric Volumetric, ox.-red. Colorimetric Identification Polarographic Review Biological Electrophoretic Polarographic Spectrophotometric, infrared Spectrophotometric, ultraviolet Chromatographic, gas Chromatographic, paper Colorimetric Identification Polarographic Spectrophotometric Stability Volumetric, acid-base Volumetric, complexometric Volumetric, ox.-red. Chromatographic, paper Colorimetric Polarographic Stability Volumetric, acid-base Chromatographic, paper Chromatographic, thin layer Colorimetric Electrophoretic Extractive Fluorometric Identification Chromatographic, paper Colorimetric Fluorometric Stability Chromatographic, thin layer Identification Polarographic Spectrophotometric, ultraviolet Volumetric, acid-base Specifications Chromatographic, gas Chromatographic, partition Chromatographic, thin layer Colorimetric Crystallographic Microbiolo ical Polarogra p t ic Spectrophotometric, ultraviolet Stability Chromatographic, thin layer Spectrophotometric, ultraviolet

(am (116, 686, 948, 1887') (860, 8377, 8663) (891) (8009) (I401 j

(1688;8064) (1039, 1307) (1088, 8064) (1471) (688, ,9064) 11688)

( 1683) (181, 1688) (46) (1683)


(Continued) ~

~

~~

VOL. 41, NO. 5, APRIL 1969

205

R

Table IV.

Nitrogen-Containing Compounds (Confinued)

Compound or class

Method or subject

References

Oxadiazoles Oxazolidines Oxazolidinones

Polarographic Specifications Chromatographic, column Polarographic Colorimetric Volumetric, acid-base Chromatographic, paper Chromatographic, thin layer Identification Polarographic Volumetric, complexometric Volumetric, ox.-red. Chromatographic, thin layer Gravimetric Polarographic Review Stabiiitv Volumeiric, complexometric Volumetric, precipitation Chromatographic, thin layer Colorimetric Gravimetric Identification Suclear magnetic resonance S ecifications olumetric, acid-base Spectrophotometric, ultraviolet Calcium determination in Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Electrophoretic Polarographic Spectrophotometric, ultraviolet Volumetric, acid-base Volumetric, conductometric Volumetric, ox.-red. Review Chromatographic, paper Identification Stability Amperometric Automatic analysis Chromatographic, ion exchange Chromatographic, paper

(1644) (1968)

Oxazolineones Phthalazines

Piperazines

Piperidines

J

Pteridines Purines

Pyrazines Pyrazolidines Pyrazolines Pyrazolones


Pyridazines Pyridines

Differential thermal analysis Gravimetric Identification Polarographic Refractometric Review Spectrophotometric, ultraviolet Stability Volumetric, acid-base Volumetric, conductometric Volumetric, ox.-red. Volumetric, precipitation Chromatographic, paper Chromatographic, thln layer Spectrophotometric, ultraviolet Chromatographic, column Chromatographic, paper Chromatographic, thm layer Colorimetric Extractive, ion pair Fluorometric Gravimetric Identification

~


(1690)

(536B,1946) (17, 1090, 1926, 1946, 2633B) (240)

(732, 1946) (1933)

f23

(666)

(2320) 123691

(ir8oj ( 1826)

(1823) (1586) (2169) (8169) (1971)

(1216) (16, 249, 623, 624, 806, 1267, 1687, 1868) (11, 101, 14.8, 383, 619, 749, 104.8, i i o r , i i 6 8 , i i 6 9 , 1 ~ 4 , i 3 714.86, ~, 14.26, 2063, 2066, 2270, 2896, 2896) (1331)

1397) (474; 891, 8067, 2169) (1339) (1495) (2026) 806,1215, 1474, 1476, 1687) (16, (16,290, 806,1667,168r, 1864) (666. 760)

(8110) (1670, 1680, 1686) (386, 389, 606, 817) (669, 14.48, 1449, 1988)

188.L

(Continued)


206 R

(1120)

(1120) (1706) (2083) (392)

~~


Pyridones Pyrimidines

Pyrimido pyrimidines Pyrroles Pyrrolidines Pyrrolidones Quaternary ammonium compounds

Quinolines

Quinazolines Triazines Uracils

Urea and derivatives

Xanthines

Nitrogen-Containi,igCompounds (Continued)

Method or subject

References

Specifications Spectrophotometric, ultraviolet Spot test Stability Volumetric, acid-base Volumetric, complexometric Extractive Spectrophotometric, ultraviolet Chromatographic, gas Colorimetric Electrophoretic Gravimetric Identification Polarographic Specifications Spectrophotometric, ultraviolet Stability Volumetric, acid-base Volumetric, ion pair Crystallographic Identification Colorimetric Chromatographic, thin layer Colorimetric Identification

(296) (389, 1680, 1988, 8110) (2535) (389, 1680, 1686, 8063) ( 1928) (767) ( S B , 11478) (55,11475) (2509) (2535) (291) (1220) (126) (1463) (2588) (1844, 1845s) (773) (1843, 1846) (2092) (2509) (2509) (1711) (1390) (1508) (1508)

Chromatographic, gas Colorimetric Crystallographic Identification Partition coefficients Review Specifications Spectrophotometric, infrared Spectrophotometric, ultraviolet Stability Volumetric, acid-base Volumetric, precipitation Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Crystallographic Extractive Fluorometric Identification Polarographic Spectrophotometric, infrared Spectrophotometric, ultraviolet

(1281) (21, 140, 799, 1270, 2163)

(SYOi (370; 1130) (188; (188, 799)' (1271) (907) (580, (1&SqB) 799, l@dB, 8330, 2349) (580, 799, l@dB, 8330, 2349) 12L09)

(901) (2415, 1400, 2 4 1 7 ~ ) (1439) (140, 8399, 8476) 11603. 1989)

Volumetric, ox.-red. Identification Volumetric, acid-base Volumetric, precipitation Characterization Chromatographic, paper Colorimetric Spectrophotometric, infrared Spectrophotometric, ultraviolet spot test Stability Volumetric, acid-base Volumetric, ox.-red. Volumetric, precipitation Chromatographic, partition Chromatographic, thin layer Colorimetric Identification Polarographic bpecifications Spectrophotometric, infrared Volumetric, complexometric Volumetric, precipitation chromatographic, gas Chromatographic, thin layer Identification Nuclear magnetic resonance Spectrophotometric, ultraviolet Volumetric, acid-base


VOL. 41, NO. 5, APRIL 1969

207 R

Table V. Compound or class Acids and derivatives Carboxylic acids Aliphatic

Aromatic

Esters

Salicylic acid and derivatives

Oxygen-Containing Compounds

Method or subject

References

Chromatographic column Chromatographic, gas Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Colorimetric Dye transfer Enzymatic Extractive Flotation analysis Gravimetric Identification Polarimetric Polarographic Specifications Stability Volumetric, acid-base Volumetric, complexometric Volumetric, ox.-red. Chromatographic, column Chromatographic, gas Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Collaborative study Colorimetric Electrophoretic Extractive Identification Radiometric Refractometric Review Spectrophotometric, flame Spectrophotometric, ultraviolet Spectrophotometric, X-ray Volumetric, acid-base Volumetric, conductimetric Volumetric, coulometric Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Exrractive Identification Polarographic Specifications Spectrophotometric, ultraviolet Stability Volumetric, ox.-red. Automatic analysis Chromatographic, column Chromatographic, gas Chromatographic, gel filtration Chromatographic, paper Chromatographic, thin layer Collaborative study Colorimetric

(1418B) (SO, 681) (1151) (1975, 2180, 2196) (497, 1509, 2180, 2343) (556, 1418B, 1509, 2490) (2067, 2256) ( 1638)

Determination of impurities in Dye transfer Extractive Fluorometric Microdiff usion Reflectometric Review Spectrophotometric, ultraviolet Spectrophotometric, X-ray Spectrometric, mass Stability Volumetric, acid-base Volumetric, coulometric Volumetric, oscillometric Volumetric, ox.-red. Aldehydes

(2256) (1985. 1981)

(78;2552) (285) (1722)

(1151) (1679) 1910.2085) i2L5ii

(2472j (522, 147sB) (230B,417, 1150) (66B, 1150, 2051) (2465) (HE, 147SB)

(322) (1389, 2452) (1250) (1803)

(9311 (522) (354, 505, 1266, 2468) (718, 1404, 1858) (53B,147, 1,299, 2050, 2051, 8081) (635 786, 2020) (1299, 1352B)

[Kl) (907, 1069)

( 1185, 1299, 1858, 2082) (366, 859, 1855, 2082) (15328) (2064) (245Zl 2464)

(411) (1796B) (186g8) (568,625, 754, 1156)

\%:&85, 552, 565, 694, 1156, 1&?O, 2229, 2250, 2288, 2496, 8617, ,95568) (570, 2104) (2068, 251 7 )

(4299

(;asB,126gB, 1796B)

(2226) (171j602, 603, 610, 989, 1185, 1528, 1536, 1973, 2221, 2486) (480, 655, 1512-1516, 1477, 1485, 1817) (2467) ' (2338)

(1087, 1477, 2085)

Chromatographic, gas Chromatographic, ion exchange Chromatographic, thin layer Colorimetric Differential thermal analysis

BAnalysie of pharmaceuticals in biological media.

208 R

(30)

ANALYnCAL CHEMISTRY

(Continued)

Table V. Compound or class

Anhydrides Carbohydrates

Oxygen-Containing Compounds (Continued)

Method or subject

References

Polarographic Spectrophotometric, ultraviolet Volumetric. acid-base Volumetric, conductometric Volumetric, ox.-red. Volumetric, precipitation Chromatographic, gas Chromatographic Chromatographic, gas Chromatographic, gel filtration Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer

(597, 1723) 11209. 1526) (636,' 1111 ) '

Colorimetric Enzymatic Fluorometric Identification Polarimetric Polarographic Review Review, methods Spectrophotometric Spectrophotometric, ultraviolet Stability

Chromones

Coumarins

Furocoumarins

Ethers

Fats and oils

Furan and derivatives

Volumetric argentometric Volumetric, complexometric Volumetric, ox.-red. Chromatographic, paper Chromatographic, thin layer Colorimetric Identification Spectrophotometric, infrared Spectrophotometric, ultraviolet Chromatographic, gas Chromatographic, paper Colorimetric Fluorometric Identification Nuclear magnetic resonance Phosphorescence Polarographic Chromatographic Chromatographic, column Chromatographic, paper Chromatographic, thin layer Colorimetric Spectrophotometric, ultraviolet Spectrophotometric, visible Chromatographic, gas Chromatographic, paper Colorimetric Extractive Refractometric Spectrophotometric, ultraviolet Volumetric, ox.-red. Acetyl value Chromatographic, column Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Review, food regulations Saponification value Spectrophotometric, ultraviolet Stability Volumetric Volumetric. ox.-red. Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Crystallizrttion Microbiological Polarographic Spectrophotometric, ultraviolet Volumetric, acid-base

(5352

(1240 (1606) (790) (2393) 11885B) (448, 1017, 1018, 1245) (1526, 2180) (86, 988, 1075, 1289, 2320, 1387, 2180, 2262, 2428, 2492) (790,915,1017, 1018, 1080, 1163, 1669, 1855, 2492) (1545) (406, 407) (9, 184, 664, 1232) (1243, 1261) (9911 (754) (593) (1669) (514, 679, 1546) 1914, 1098, 1123, 1495, 1666, 1686, 1631, 1976, 2093, 2433) (353)

(871

(363, 463, 616, 854, 1310, 1669)

(1801, 1878, ,!?logB, 2281 ) 163, 920) (42QB,8ggB) ($logB,2128) ( 1865) (89gB) (2107, 2108)

(1223)

(828, 1438) (231 (2469) 123)

(688, 1878) (331. 2000. 2637) 1188) (688; 1592) (1576) (663, 2194) (1887) (2085) (492, 1635) (408) (2564) (64, 108, 2377, 2564) (844) (1015B) (1015B.2181) (309) (151, 533)


(Continued) ~

~~

VOb. 41, NO. 5, APRIL 1969

209 R

Table V. Compound or class Glycosides Cardiac glycosides

Digitoxin

Flavones

General Lanatosides

Miscellaneous

Saponins

Squill glycosides

Strophanthin


Method or subject Biological Chromatographic, column Chromatographic, paper Chromatographic, thin layer Colorimetric Identification Radiometric Review Review, methods Volumetric, acid-base Chromatographic, column Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Extractive Identification Microcrystallographic Stability Chromatographic, paper Chromatographic, thin layer Fluorometric Iden tifi ea t ion Spectrophotometric, infrared Spectrophotometric, ultraviolet Volumetric, complexometric Chromatographic Review, stability Chromatographic Chromatographic, paper Chromatographic, thin layer Colorimetric Microcrystallographic Stability Chromatographic, column Chromatographic, thin layer Colorimetric Electrophoretic Identification Spectrophotometric, ultraviolet Stability Volumetric, acid-base Volumetric, ox.-red. Chromatographic, column Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Densitometric Extractive Identification Review, methods Review, official methods Spectrophotometric, ultraviolet Agar diffusion Chromatographic, column Chromatographic, paper Chromatographic, thin layer Colorimetric Densitometric Gravimetric Identification Review Review, methods Chromatographic, column Chromatographic, paper Chromatographic, thin layer Colorimetric Identification Chromatographic, paper Chromatographic, thin layer Colorimetric

Hydroxyl, alcoholic Acetylenic alcohols

Extractive Spectrophotometric, ultraviolet Stability

a

(563,'1004, 1797, 1855, 2549) (1001, 1049, 1050, 2271, 2554) (f33GB) ill113

'

(103, 880, 1000B,1340B, 1826, 2506) f103

(640: 939)

(1564) (1549, 2201) (1391, 1650) (547,619, 1555, 2248) (619) i445j (547, 1250) (294, 574, 1250) (2443 (1588, 2426) (1224) (224, 565, 1460) (557, 1013, lS40B, 1364, 1460) (224, 553, lZZ.4, 1S40B, 1460, 2 f O d ) (1564) (1224; 1460) (110)

( 1668, 17.81, 21 62) (1668, 172'1, 2491)

(2583, 2384) ( 1383) (1114)

(691) (436, 704, 894, 1264, 1331, 1557) (24)56, 221, 1855, 1882, 1923, 2015) (436, 691) (56, 1882) (894, 1357) (1291) ( 1507) (1331) (6'62)

iSOO7,

tm

(232, 2'569) 1232)

(2369) (1031, 1346, 2567) (70f, 785, 893, 1231, 1351, 1562, 1877,

2567) (701, $85, 895, 1051, 1351, 1552, l S 4 6 , 1826, 2567) (2404) (8)

(110, 1345-1348, 1351, 1352)

Chromatographic, paper Identification Volumetric, complexometric


210 R

References


(Continued)

Table V. Compound or class Chlorobutanol

Ethanol General Menthol Miscellaneous

Terpin hydrate Hydroxyl, phenolic

Oxygen-Containing Compounds (Continued]

Method or subject

References

Chromatographic, gas Collaborative study Radiometric Stability Chromatographic, gas Refractometric Colorimetric Volumetric, ox.-red. Colorimetric Chromatographic, gas Chromatographic, thin layer Colorimetric Identification Spectrophotometric, ultraviolet Stability Chromatographic, gas

(555, 1188) (458, 864)

Chromatographic, column Chromatographic, gas Chromatographic, paper Chromatographic, thin layer

(968, 1418B) (503. 777.ldL8.1866.1735.8L68.28781

Collaborative study Colorimetric

(KK)

Crystallographic Densitometric Dye transfer Electrophoretic Extractive Gravimetric Identification Nuclear magnetic resonance Polarographic Review, methods Spectrophotometric, infrared Spectrophotometric, ultraviolet Stability Volumetric, am erometric Volumetric, couPometric Volumetric, ox.-red. Hydroxyl, polyhydric

Chromatographic, column Chromatographic, gas Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Colorimetric Enzymatic Extractive Flotation analysis Identification Official method Polarimetric Polarographic Spectrophotometric, ultraviolet Stability Volumetric, ox.-red.

Ketones

Chromatographic, gas Chromatographic, ion exchange Chromatographic, thin layer Colorimetric Physical and chemical propertiea Polarographic Spectrophotometric, ultraviolet Volumetric, acid-base Volumetric, conductometric Volumetric, ox.-red.

Lactones

Chromatographic, column Chromatographic, thin layer Spectrophotometric, ultraviolet Stability Colorimetric Review, methods Stability Chromatography, thin layer Colorimetric

Peroxides Quinones

BAnalyuiu of pharmaceuticalsin biological media.

(800.9)

(1676, 1849) (1731, 9444) (2484) (1083, 8318) (1083, 1881) (189) (681 1438, 8099) (15&, 8081) (1946) (1946) (2082) (8099) (1233,1845, 1846, 1 3 m )

(147,'166,2'@, 4i9, 4 4 4 457, 551, 1018B, 1073, 1136, 1188, 1899, 1648, 204o,8050,2o97, 2249)

(li:101, 179, 216, ,943, 446, 522, 670,

786, 997, 1136, 14188, 1458, 1468, m r , 1 5 5 8 , 1 9 ~1318,2374) , (1929) (568, 1461) (2067) (1538) 1299, 133%,23r4) (1758) (599, 1021, 1869, 8160) (1869;$101j (1513. 1608. 1735) (898,584, 1058, 1198, 1899, 1838, 1868, 8660) (1853)

(1815) (389, 354, 686, 84?'lB) (448) (23) (50, 878, 484, 633, 8488) (101, 484, 661, 1693, m r , 8020,1455) (432) (83) (8866) (817)

(1915)

(8835) (803)


211 R

Table V. Compound or class

Xanthenes


Method or subject

References

Differential scanning calorimetry Gravimetric Review, methods Volumetric, ox.-red. Chromatographic, paper Spectrophotometric, ultraviolet Stability

(1875) (768) (688) (1440) (1807, 14.90) (1207, 1480, 2349) (4% 1207)

Table VI.

Stability (General)

Compound or class

Method or subject

References

Drug stability

Effect of impurities Government regulations Kinetics Review

Oils, fats Parenterals

Review Drug chemical compatibility Sterilization Effects of radioactive irradiation Interaction with plastics Interaction with rubber closures Oxidative deterioration Prediction of stability Incompatibility of components Review Stabilization with Tweens Effects of moisture Review

(1699) (4211 (676, 677, 734, 1708, 1873, 2068, 1884) (304, 305, 678, 1228, 8260) (8477) (664, 1661) (1115) (1198) (85)

Pharmaceuticals

Suspensions Tablet formulations

Table VII. Compound or class Adrenocorticals Aldosterone

Corticosterone

Cortisones

Dexamethasone

Fluoroprednisolone Epicortisol General

Hydrocortisone

(2141) (8161) (2878)

Steroids and Hormones

Method or subject

References

Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Electrophoretic Extractive Radiometric Stability Chromatographic, column Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Densitometric Enzymatic Extractive Fluorometric Polarographic Radiometric Chromatographic, thin layer Colorimetric Crystallographic Densitometric Identification S ectrophotometric, ultraviolet CRromatographic, paper Chromatographic, thin layer Colorimetric Crystallographic Enzymatic Chromatographic,. partition Spectrophotometric, ultraviolet Stability Chromatographic, thin layer Polarographic Chromatographic, gas Chromatographic, thin layer

(184rB, 1848) (1366rB) (1880, 1881) (199) (236rB) (836rB) (1848) (5408 641) (1847% (1944, 2367B) (886, 1880, 1918, 1944) (1944) (1918) (1944) (720B,88678) (540B,6418, 780B, 16GB, 2996) (896) (2367B) (591, 836, 1918)

Colorimetric Polarographic Spectrophotometric, infrared S ectrophotometric, ultraviolet CRromatographic, column Chromatographic, paper Chromatographic, thin layer Colorimetric

BAnslysis of pharmaceuticalsin biological media.

212 R

[%&) (2358)


tf3h 17%) (1944)

(1918)

(194-4) (1944) (1838) iiif%8) (99) (288)

(826) (826) (747, 84.9) (344, 487, 826, 938, 1366, 16048, 1821, 1917) (344, 933, l@bB) (886) (1447) (1604B) (268, 540B, 541B, $110) ($461) (903,591, 706B, 1918) (858, 804, 1801, 8555)

(Continued)

Table VII. Compound or class

Prednisolone

Prednisone Triamcinolone

Androgens Androsteneols Androsterone

Methandrostenolone Testosterone

Estrogens Estradiol

Estriol Estrone

Ethinylestradiol

General

General

Steroids and Hormones (Continued)

Method or subject Densitometric Fluorometric Identification Polarographic Spectrophotometric, infrared Spectrophotometric, ultraviolet Spectrophotometric, X-ray Stability Chromatographic, paper Chromatographic, thin layer Colorimetric Crystallographic Dissolution Enzymatic Identification Spectrophotomet.ric, infrared Spectrophotometric, ultraviolet Colorimetric S ectrophotometric, ultraviolet dromatographic, paper Chromatographic, thin layer Colorimetric Enzymatic Chromatogra hic CrystallograpKic Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Crystallographic Fluorometric Stability Colorimetric Chromatographic, column Chromatographic, gas Chromatographic, thin layer Colorimetric Polarographic Spectrophotometric Spectrophotometric, ultraviolet Chromatographic, column Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Identification Polarographic Chromatographic, gas Chromatographic, thin layer Enzymatic Chromatographic, column Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Identification Volumetric, acid-base Chromatographic, gas Chromatographic, thin layer Colorimetric Fluorometric Identification Spectrophotometric, infrared Spectrophotometric, ultraviolet Stability Volumetric, acid-bsse Chromatographic, gas Chromatographic, partition Chromatographic, thin layer Colorimetric Enzymatic Spectrophotometric, infrared Chromatographic, Chromatographic, Chromatographic, Chromatographic, Chromatographic, Chromatographic,


adsorption column gas paper partition thin layer

References 163gB, l64SB, 1996)

(778, 1201, 1944) (1838) (2231) (1944) 11388) (1388; 1694) (1801 ) (1201) (1201) (1944

(1324) (1238) (16gB 630B, 1226, 2382) (13 6 ~ 5 ~ ) (16dB, 18fgB,1886, 8660s) (792, 1366B, 2131) ( 1238) (8650B) (1836) (1199) ($1 12) (296, 1286, 1633, 1646) (lY8, 1286) ( f 7 8 ,798, 1800) (2140)

(8118) (1100, 8638)

(116jB,1663)

'

( Y U - Y.LTLr ), L . 7 -

(863, 689, 2072) (881, 904, 944)

(414, 881, 904, 944, 8073, 8887, 8396)

(414, 11866) (1662) im4j

(128, 1866, 8078) (1266, 8439) (1668) (475, 1279) (196B) (170, 1113, 138.8, 8166) (196B) (196B) (170)

(1544) (83, 148, 348, w ,610, 636, 842, 1386, 2034, 8136, 8317, 8648) (CO?%tinued)

VOL. 41, NO. 5, APRIL 1969

213 R

Table VII.

Steroids and Hormones (Continued)

Compound or class

Method or subject

Insulin

Colorimetric Electrophoretic Extractive Identification Nuclear magnetic resonance Polarographic Spectrophotometric Spectrophotometric, infrared Spectrophotometric, ultraviolet Stability Bioassay Chromatographic, paper Chromatographic, thin layer Electrophoretic Identification Review, methods Stability Chromatographic, gas Chromatographic, paper Chromatographic, thln layer

Oxosteroids

Phytosterols

Pregnane

Progesterone

Sterols

References

Circular dichroism Colorimetric Optical rotatory dispersion Polarographic Volumetric, acid-base Chromatographic, gas Chromatographic, thin layer Colorimetric Gravimetric Volumetric Chromatographic, gas Chromatographic, thin layer Colorimetric Identification Spectrophotometric, infrared Chromatographic, column Chromatographic, gas Chromatographic, thin layer Colorimetric Enzymatic Fluorometric Polarographic Spectrophotometric, ultraviolet Chromatographic, column Chromatographic, gas Chromatographic, thin layer Colorimetric Densitometric Identification Spectrophotometric, ultraviolet Volumetric, ox.-red. ~

Table VIII.

~

(236, 866, 348) (692) (lY60, 1808) (1930) (26, 813, 10'76) (2408) IW) (1306) (867, 23Y9) (1688, 349, l2Y9, 2656) (698B, 2666) (162B,836, 1109, 121gB, 1323, 13BY, 1669, 1560, 19Y7, 22YY) (1648) ( m r ,1 3 6 5 ~ ) (1649) ('762,2139) VG,~ 4 6 )

(211P ) (2666) (178, 11Y6, 2111B, 82Y6) (178, ~ 9 2 ) 12111B)

B l l Y , 2193,

~~~

Sulfur-Containing Compounds

Compound or class

Method or subject

References

Beneothiadiaaines

Chromatographic, paper Chromatographic, thin layer Colorimetric Monogra h Spectropgotometric, infrared Spectrophotometric, ultraviolet Stability Volumetric, mercurometric Chromatographic, thin layer Colorimetric Polarographic Spctrophotometric, infrared olumetric, chelatometric Volumetric, precipitation Chromatographic, gas Colorimetric Polarographic Chromatographic, paper Chromatographic, thin layer Colorimetric

(1Y3YB) (1393, 2120)

Cyclohexylsulfamates

Disulfides Mercaptans

BAnalyeis of pharmaceuticals in biological media.

214 R


(8618, b 1 9 ) (8242)

(1608) (1319) (483) (1662) ( 1656, 1666) (1603, fB18)

(Continued)

Table VIII. Compound or class

Sulfur-Containing Compounds (Confinued)

Method or subject Polarographic Specifications Spectrophotometric, infrared Stability

Miscellaneous

Colorimetric Gravimetric Identification Polarographic Specifications Volumetric, argentometric Volumetric, precipitation

Phenothiazines

Analytical screening Chromatographic, gas Chromatographic, ion exchange Chromatographic, paper Chromatographic, partition Chromatographic, thin layer Collaborative study Colorimetric Electron paramagnetic resonance Fluorometric Gravimetric Identification Particle size distribution Polarographic Review Review, methods Riboflavine complex Spectrophotometric, infrared Spectrophotometric, ultraviolet Stability Surface activity Volumetric, acid-base Volumetric, amperometric Volumetric, oscillometric Volumetric, ox.-red.

@6s:618. 1105) (203, 2512, 1792) (l%iB,203, 1003B, 158dB) (2142) (203, 362, 403,456, 606, 659, 707, 100SB, 1167, 1506, 1546, 1673, 1934, 1980, 2182, 2267, 2389, 2563) (264) (113, 13SB, 23lB, 1086, 1151, 1456, 1637, 1 7 2 8 ~2439) , (1302) (1830, 1831B) 1208. 3961 (5621 403; 550, 625B, 1024, 1754, d198, 2396) (1110) (528, f792) 1605. 1.401) ~ o g i' '

1934, 2142, 2182,

(395,396, 2024) (149, 150, 208, 1517) (2338) (202, 1514)

Phosphorothioates

Stability

Saccharin

Chromatographic, thin layer Determination of impurities Dye transfer Spectrophotometric, infrared

(943) (815) (1133) (2067, 2068) (1612)

Sulfide

Chromatographic, thin layer

(613)

Sulfonamides

Chromatographic, gas Chromatographic, paper Chromatographic, thin layer

1870. 2309)

Colorimetric Dialysis Diazometry Dissociation constant Dissolution rate Fluorometric Identification Microbiological Mole ratio method Phosphorimetric Polarographic Review Review, methods Spectrophotometric, infrared Spectrophotometric, ultraviolet Spectrophotometric, X-ray Stability Thermal analysis Volumetric, acid-base Volumetric, amperometric Volumetric, coulometric Volumetric, ox.-red. Sulfones

Chromatographic, thin layer Stability


(1287) (1580)

(795, '1960)' (4, 1446, 1594, 1616) (427, 716, 1040, 1466, 1842, 1981) (1250, 1253) (60, 308, 1191. 1887) (12) (151, 533, 1180, 2411) (160) (193, 551) (163, 573, 578, 796, 1468, 2.%?38, 2411, 6528) (613, 1257)

(418)


215 R

Table VIII.

Sulfur-Containing Compounds (Continued)

Compound or class

Method or subject

References

Sulfonic acids

Colorimetric Identification Official method PolarographicSpectrophotometric, infrared Spectrophotometric, ultraviolet Stability Turbidimetric Volumetric, acid-base Volumetric, ox.-red. Volumetric, precipitation Chromatographic, ion exchange Chromatographic, thin layer Colorimetric Identification Volumetric, acid-base

(383, 522, 670) (2058) (461) (2356) (1610, 1615) (m,1030, 2348) (1537) (1318) (750) (755) (183, 2253) (1206) (1666) (1603) (1206) (1206)

Sulfophthaleins

Chromatographic, paper Chromatographic, thin layer

(945) (119, 945, 946)

Sulfoxides

Chromatographic, paper Colorimetric Identification Volumetric, ox.-red. Chromatographic, paper Colorimetric Spectrophotometric, X-ray fluorescence

(660) (660, 2449)

Sulfonium salts

Thiadiazines Thianthrene Thiazine Thiazole Thiazolidine Thioamides

Thiobarbituric acids Thiophene Thiosemicarbizone Thiouracils Thiourea

Thioxanthines Thioxolones

Analytical screening Identification Spectrophotometric, infrared Polarographic Colorimetric Chromatographic, paper Spectrophotometric, ultraviolet Stability Volumetric, complexometric

(1680) ( 1680) (1680, 2053) (767, 770)

Identification Spectrophotometric, ultraviolet Colorimetric

(21.69) I1 769) (1018, 1090, 1096)

Gravimetric Volumetric, ox.-red. Spectrophotometric, ultraviolet Spot test Chromatographic, paper Colorimetric Identification Solubility Stability Volumetric, acid-base Volumetric, argentometric Spectrophotometric, infrared Colorimetric Spectrophotometric, ultraviolet Volumetric, acid-base

(768) (4811 (1550) (1388) (1730)

Table IX.

(260B)

($414) ($414)

(1554) (1554) (3414) ($414) (2188) (1937) (1927) (igsrj

Vitamins

Chromatographic, paper Chromatographic, thin layer Colorimetric Determination of BHA and E H T in Fluorometric Hydrogenation Identification Review Spectrophotometric, ultraviolet Stability Chromatographic, adsorption column

Vitamin D

Chromatographic, gas BAnaIysis of pharmaceuticals in bioiogical media. ~~

216 R

(176) (419) (1108, 1368) (89YB)

Method or subject

Compound or class Oil-soluble Vitamin A

(2lY9) (40) (2010) (8010) (1837)


References

1811)

,

'--Ti

(49, 1362, 162gB, 2850, 2251)

(65, 1395, 1405, 1889, 2061) (1159, 1168, 1396, 1626, 1671 950, 2302) (87, 211, 1158, 1161, 1619O, 16318, 2432)

(Continued)

Table IX. Compound or class

Vitamin E

Vitamin K

Water-soluble B group

BI, thiamine

B1, riboflavin

Bo, pyridoxine

BI2,cobalamine

B I ~pangamic , acid Biotin

Vitamins (Continued)

Method or subject

References

Chromatographic, thin layer Colorimetric Fluorometric Polarographic Stability Chromatographic, adsorption column Chromatographic, gas Chromatographic, thin layer Colorimetric Fluorometric Polarographic Spectrophotometric, ultraviolet Volumetric, ox.-red. Chromatographic, adsorption Chromatographic, gas Chromatographic, gel Chromatographic, partition column Colorimetric Mass spectrometric Polarographic Review Spectrophotometric

(888, 1053, 1160, 1163, 21 73, 2333) (404, 1396, 1950) (1671

(2218) (645, 1553, 2299, 2302, 2303) (489, 1O6rB) (256, 295, 1532, 1736, 2042) (ZOO, 1053, 2060, 2235) (200, 343, 2316) 18115) (1512, ?&28) (995, 1511) (1748) (425, 928, 1304, 2382) (1593) (1423) 117.48)

Chromatographic, thin layer Electrophoretic Spectrophotometric, ultraviolet reflectance Chromatographic Chromatographic, ion exchange Chromatographic, thin layer Colorimetric Electrophoretic Fluorometric Gravimetric Mass spectrometric Microcrystalloscopic Review-,identification Spectrophotometric, ultraviolet Spectrophotometric, ultraviolet reflectance Stability Volumetric, acid-base Volumetric, complexometric Volumetric, ox.-red. Volumetric, precipitation Chromatographic, ion exchange Chromatographic, thin layer Colorimetric Complex with phenothiazines Electrophoretic Fluorometric Microbiological, acidimetric Spectrophotometric, ultraviolet Stability Chromatographic, gas Chromatographic, paper Chromatographic, thin layer Colorimetric Electrophoretic Fluorometric Microbiological Official method Spectrophotometric, ultraviolet Spectrophotometric, ultraviolet reflectance Volumetric, acid-base Volumetric, oscillometric Chromatographic, gel Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Colorimetric Densitometric Electrophoretic Extractive Isotopic dilution Microbiological Polarographic Radiometric Review Spectrophotometric, ultraviolet Stability Spectrophotometric, infrared Stability, hydrolytic Microbiological


ii8.40)

i14ii j (4-4.2)

(1166, 1156, 1202, 1203, 2293) (2218) (1363) 11479, 1632) 1960. 1606. 1812. 188.4)

csooi

(1697) (1718-1720) (437, 846, 1919, 1992) 132.4. 391. 4.996. 1720. 1787. 1986)

(18545)

(982, 1055, 1689, 1919)

(961)

(1179, 1181) (2114) (324, 394, 1718) (129, 1178, 1698) (638) 12534) (1876)


217 R

Table IX. Compound or class C, ascorbic acid

Vitamins (Continued)

Method or subject Chromatographic, gas Chromatographic, ion exchange Chromatographic, paper Colorimetric Electrophoretic Fluorometric Polarographic Review Spect’rophotometric,ultraviolet Stabilitv VolumeEric, complexometric Volumetric, ox.-red.

References (2320, 2860) (789) (1098, 1121, 1766, 2sog-wiz) (72, 668, 1081, 1181, 1213, 1766, 2080, ~~91,234r) (1293)

(94,608, 1229, i4r9, I S @ , $207) (93, 1813) (488, 789, 867, 91@, 980, 1610, 6435, 9/fifi\

Folic acid

General

Nicotinamide

Pentothenic acid

Vitamin P

Chromatographic, adsorption column Chromatographic, paper Chromatographic, partition column Chromatographic, thin layer Colorimetric Fluorometric Review, pharmacopoeial methods Chromatographic, paper Chromatographic, thin layer Colorimetric Fluorometric blicrobiological Production control methods Review, colorimetric methods Spectrophotometric, ultraviolet Spectrophotometric, ultraviolet reflectance Chromatographic, paper Chromatographic, thin layer Colorimetric Electrophoretic Microbiological Spectrophotometric, ultraviolet Volumetric, complexometric Volumetric, oscillometric Chromatographic, thin layer Colorimetric Review Spectrophotometric, ultraviolet Colorimetric

Table X. Compound or class General methods Aerosols Alcohols Alkoxy group N-Alkyl group Analgesics Anesthetics Anesthetics, local Antiacids Anticonvulsives Antihistamines Antimycotics Antineuralgics Antioxidants Antipyretics Antituberculars An titussives Cardiokinetics Cationic drugs Contraceptives Curarimimetics Diuretics Dyes

e

(846) (1344) (816, 2149) (926, 1898) (1344) (919) (120, 463) (862, 1822) (463) (463) (606)

(824) (38) (120, 1363) (1308) (418) (816) (33ZB,249gB)

ilQ% (412, 543, 1466) (93) (537, 2338) (816, 987) (1165) (88) (927, .m31) (1912)

Formulations, Mixtures, and General Methods

Method or subject

References

Chromatographic, gas Sampling Review, methods Chromatographic, gas Chromatographic, gas Chromatographic, thin layer Review, method progress Chromatographic, gas Polarographic Review, methods Chromatographic, thin layer Colorimetric Identification Chromatographic, thin layer Chromatographic, ion exchange Chromatographic, thin layer Spectrophotometric, ultraviolet Chromatographic, paper Extractive Chromatographic, thin layer Chromatographic, thin layer Extractive Review Review, method progress Chromatographic, thin layer Chromatographic, thin layer Interaction with polymers Chromatographic, thin layer Microbiological Chromatographic, thin layer Identification Chromatographic, thin layer Review, methods Chromatographic, paper Chromatographic, thin layer

(462, 908)

BAnalysis of pharmaceutical8 in biological media.

218 R

(2TZi’


(2300)

(1011) (1996) (1996) (1862) (1011) ( r a , 18.59, 2493q (318) (1119) (347) (2424) (473) (2614) (1492) (728) (1492, 2444) (726) (2163) (1406, 2021) ( 1862) (2153) (2163) (1011) (1406, 2021)

{;a)

(1113, 1899) (2301)

(2494) (600)

(807,1649) (8166)

(161, 1329, 13996) (297, rsm) (Continued)

Table X. Compound or class

General techniques

Formulations, Mixtures and General Methods (Continued)

Method or subject Identification Spectrophotometric, ultraviolet Stability Acylation Automated techniques Chromatographic Chromatographic, gas Chromatographic, ion exchange Chromatographic, paper Chromatographic, thin layer Colorimetric Dissociation constants Dissolution rate Electrophoretic Flask combustion Fluorometric Functional group Identification of solid dosage forms Instrumental Microbiological Microsco ic characterization Microsub%mation Neutron activation Nuclear magnetic resonance Official methods Oscillopolarographic Particle distribution Phytochemical analysis Radiometric Review Ring oven Spectrophotometric, infrared Spectrophotometric, internal reflectance Spectrophotometric, ultraviolet

Hallucinagens Hypnotics Insecticides Liniments Methoxyl group Narcotics Ointments Paraffins Parenterals Preservatives Psychedelics Psychole tics Psy chopiarmacologicals Psychotherapeutics Radiopacs

Radiopharmaceuticals Salves Sedatives Surfactants Sympathomimetics Tranquilizers

Spot tests Tablet disintegration Toxicological Turboextraction Volumetric, acid-base Volumetric, coulometric Volumetric, ox.-red. X-Ray Chromatographic, thin layer Chromatographic, thin layer Review Chromatographic, thin layer Chromatographic, gas Volumetric, ox.-red. Chromatographic, thin layer Control of metal containers Stability Thixotro y SpectropRotometric, ultraviolet Determination of particulates Refractometric Chromatographic, thin layer Chromatographic, paper Chromatographic, thin layer Chromatographic, thin layer Review, methods Chromatographic, thin layer Colorimetric Identification Radiometric Spectrophotometric, flame Spectrophotometric, ultraviolet Volumetric, complexometric Volumetric, precipitation Officjal methods Radiometric Review, detection methods Chromatographic, thin layer Chromatographic, thin layer Colorimetric Chromatographic, gas Chromatographic, thin layer Chromatographic, thin layer

BAnalysia of pharmaceuticala in biological media.

References

(737)’ (434) (1407) (42, 408, 763, 1970) (328, 1171B, 1366, 1664, 1700, 1970, $191, 2198) (1360) (9, 436, 741, 1309, 1369, 1360, 1654, 1682. 1999. 2L691

(741, ‘1870) (801)

(174i)

(1700)

IZ) (1303)

(222, 889, 1008, 1700) (2469) (861 1700, ,9228, 2539) (2441) (267, 1208, 1,909, 1211, 1366, 1450, 1989)

tgki :; (443)

(21344) (491, 1311, 2339) (368, 2178) (7, 101, 1580, 2363) (1266, 2005) (2267) (2313) (167) ($062) (779)

(4011 (2257) (1066) (877)

(877; 2267) (772)


219 R

Table X. Compound or class Tuberculostatics Formulations, mixtures, and miscellaneous Aluminum hydroxide gel Ammonium alginate Amylase Ash Azulene Benzyl alcohol Cannabis Chloroform Cholinesterase Chymotrypsin Guajacuran Hexachlorocyclohexane Lacca gum Methyl cellulose Phenylen Polyethylene oxides Polyvinylpyrrolidinone Pyrabital Rhinofuracin Sergosin Spermaceti Strychnos seeds Tars Trypsin Vegetable carbon White lotion

Formulations, Mixtures and General Methods (Continued)

Method or subject

References

Chromatographic, paper

(785)

Aging of Volumetric, flocculation Colorimetric Microbiological Radiometric Chromatographic, thin layer Chromatographic, gas Chromatographic, thin layer Identification Chromatographic, gas Stability Review, methods Chromatographic, paper Volumetric, acid-base Volumetric, iodine index Interaction with drugs Volumetric, ox.-red. Physicochemical properties Interaction with drugs Chromatographic, gas Determination of components Polarographic Chromatographic, thin layer Official method Chromatographic, thin layer Colorimetric; volumetric, acid-base Identification Formation of hydrogen peroxide

( 1578, 1579) (2354)

(166,'1218, 1629) 1978)

i5~5i


chelates in photometric analysis has been presented (2319). T h e field of fluorescence spectrometry and its applications to pharmaceutical analysis have also been surveyed (254, 615). Reviews have appeared on t h e increasingly popular field of thermogravimetry and differential thermal analysis (1643, 2274). Two symposia on automatic analysis were held which presented many papers on pharmaceutical research, process, and quality control (2233).

Some of t h e problems of drug stability, including degradation kinetics and mechanisms, have been presented (676, 1482). Johnson has surveyed t h e effects of water on drug stability and reported o n qualitative and quantitative methods for its determination (1006). The therapeutic and clinical importance of drug particle size and t h e techniques of particle size analysis have been outlined (430, 538, 2115). Gopal and I y a have reviewed t h e quality control of radiopharmaceuticals (739). T h e difficulties involved in t h e analysis of some drugs b y t h e methods of t h e International Pharmacopeia have been discussed (325). Methods of t h e German Pharmacopeia have also been discussed (882, 885). LITERATURE CITED

(1) Abdel-Monem, M. M., Soine, T. O., J. Pharm. Sci., 56 (8),976-82 (1967). (2) Abdel-Wahab, M. F., Bishara, R. H., Zh. Anal. Khzm., 219 (2), 183 (1966); Anal. Abstr., 14, 5651 (1967). 220 R


(3) Abdel-Wahab, M. F., El-Kinawy, S. A., ibid., (5), p 425; Anal. Abstr., 14, 7118 (1967). (4) ilbdel-Wahab, h1. F., El-Kinawy, S. A., Farid, N. A,, El-Shinnawy, A. M., ANAL.CHEM.,38, 508 (1966). (5) Abelson, D. M., Boyle, A., Clin. Chim. Acta, 14 (4), 483 (1966). (6) Abend, Th., Stamm, 0. A., J . Chromatogr., 26 ( l ) ,79-88 (1967). (7) Abramov, M. K., Tr. Tashkentsk. Farmatsevt. Inst., 4,524-30 (1966);Chem. Abstr., 67, 25415k (1967). (8) ~, Abudabirov. N. K.. Nikonovich. S. D.. Khim.-Farm. 'Zh.. 1 (1). 40-1 (1967); Chem. Abstr., 67, k716f (i967). (9) Abuin, J., Lobo, E. S., Arch. Bioquim., Quim. Farm. Tucuman, 11 (1,2), 109-13 (1963-64); Chem. Abstr., 65, 10645a (1966). (10) Adachi, T., Minamikawa, T., Nakaji, Y., Tanimura, A., Asahina, M., Eisei Shikenjo Hokoku, 84,22-5 (1966); Chem. Abstr., 67, 14910s (1967). (11) Adam, W., Acta Polon. Pharm., 24 (2), 161-4 (1967); Chem. Abstr., 67, 102820t (1967). (12) Adamanis, F., Wieclawski,A., Poznan. Towarz.Przyjaciol Nauk, Wydzial Lekar., Prace Komisii Farm.. 3. 61-72 11965): Chem. Abstr.: 63, 54528 (1965). (13) Adamski, R., Broda, H., ibid., 4, 187-93 (1966) ; Chem. Abstr., 66, 22269.1' \ -

I

I

~

I

,

11967).

(14,-Adamski, R., Cieszynski, T., Farm. Polska, 22 (lo), 731-7 (1966); Chem. Abstr., 67, 47112m (1967). (15) Adamski, R., Lut,omski, J., Wisniewski, J., Deut. Apotheker-Ztg., 107 (6), 185-7 (1967); Chem. Abstr., 67, 57102 (1967). (16) Adamski, R., Masiakowski, J., Pawelczyk, K., Diss. Pharm. Pharmacol., 18 (5), 515-18 (1966); Chem. Abstr., 67, 14903s (1967). (17) Adamski, S., Acta Polon. Pharm., 22 (4), 311 (1965); Anal Abstr., 13, 6503 (1966).

(18) rldiseno j 0 , S.,Suara Pharm. Madjalah, 8 ( l ) , 1-6 (1965); Chem. Abstr., 63,

40956 (1965). (19) Affonso, A., J. Chromatogr., 22, 452 (1966). (20) Agarwal, S. P., Blake, M. I., J. Pharm. Sci., 54, 1668 (1965). (21) Aghara, L. P., Rajkotia, G. T., Vora, M. N., Zndzan J . Pharm., 29 (S), 23G-2 (1967);Chem. Abstr., 67,1028332 (1967). (22) Agurell, S., Acta Pharm. Suecica, 2 (5), 357 (1965); Anal. Abstr. 14, 1638 (1967). (23) Ahuja S. J. Pharm. Sci., 57 (2), 313-14 (1968). (24) Aizenberg, L. N., Suprunenko, A. I., Aizenberg, V. L., Tr. Kishinevsk. Sel'skokhoz. Inst., 43, 187-92 (1966); Chem. Abstr., 66, 118888m (1967). (25) Akacic, B., Kustrak, D., Acta Phurm. Jugoslav., 16 (3), 79-84 (1966); Chem. Abstr., 66, 58868t (1967). (26) Akacic, B., Petricevic, I., Farm. Glasnik., 23 (ll),489-93 (1967); Chem. Abstr., 68, 89894u (1968). (27) Akiyama, T., Fujimoto, K., Kyoto Yakka Daagaku Kakuho, 1 4 , 3 2 4 (1966); Chem. Abstr., 68, 24582w (1968). (28) Akiyama, T., Kaiju, S., ibid., pp 40-2; Chem. Abstr., 68, 43211r (1968). (29) Albu-Budai, M., Unterman, H. W., Rev. Chim. (Bucharest), 18 (3), 173-5 (1967); Chem. Abstr., 67, 676309 (1967). (30) Alcock, N. W., Anal. Biochem., 11 (2), 335 (1965), (31) Alessandro, A., Emer, R., Abbondanza, G., G. Med. Mil.,116 (6), 827-32 (1966); Chem. Abstr., 67, 254409 (1967). (32) Alessandro, A., Mari, F., ibid., 117 (3) 281-7 (1967); Chem. Abstr. 68, 16190b (1968). (33) Alessandro, A., Mari, F., Settecase, S., Boll. Chzm. Farm., 105, 761-6 (1966); Chem. Abstr., 66, 796448 (1967). (34) Alessandro, A., Mari, F., Settecase, S., Farmaco, Ed. Prat., 22 (8), 437-43 (1967); Chem. Abstr., 67, 94053c (1967).

(35) Alessandro, G., Mecarelli, E., Boll. Chim. Farm., 103 (6), 427 (1964); Anal. Abstr., 12, 5423 (1965). (36) Alexander, T. G., Koch, S. A., J . Ass. OJic. Anal. Chem., 50 (3), 676-8 (1967). (37) Alian, A., Dessouky, Y. M., Shabana, R., J.Pharm.Sci., 55 (9), 969-71 (1966). (38) Aliev, A. M., Farmatsiya (Sofia), 16 (6), 66-71 (1967); Chem. Abstr., 68, 332116 (1968). (39) Alimkhanov, 0. A,, Ikramov, L. T., Karieva, K. F., Khim. v Sel'sk. Khoz., 4 (8), 626-8 (1966); Chem. Abstr., 65, 19928h (1966). (40) Allenmark, S., Acta Chem. Scand., 20 (3), 910 (1966); Anal. Abstr., 14, 4059 (19671. (41) Alsos, I., Med. Norsk Farm. Selsksp, 29 (8),91-103 (1967); Chem. Abstr., 68, 72278y (1968). (42) Altenau, A. G., Ann. N . Y . Acad. Sn'.. 137 (1). 335-59 (1966): Chem. Absir.. 65. 1'2831~(1966). (43) Alvarei, M., Adales Farm. Hosp., 10 (21), 1 3 5 4 8 (1967); Chem. Abstr., 67, 111463f (1967). (44) Alvarez, M., Gomez-Serranillos, M., Famnawgnosia (Madrid), 26, (1-2), 1950 (1966): Chem. Abstr.. 68. 24568w (1968). (45) Amacker, P., Boymond, P., Pharm. Acta Helv., 42 (6), 357-64 (1967); Chem. Abstr., 67, 93958q (1967). (46) Amano, T., YakugakuZasshi, 85 (12), 1049 (1965); Anal. Abstr., 14, 1662 (1967). (47) Amano, T., Mizukami, S., ibid., p 1035; Anal. Abstr., 14, 1662 (1967). (48) Ambrosch, M., Pharmazie, 22 (3), 180 (1967); Chem. Abstr., 67, 254321, (1967). (49) Ames, S. R., J . Ass. Ofic. Anal. Chem., 49 ( 5 ) , 1071 (1966). (50) Amselem, A,, Achor, G., Casabonne, M., Ferrand, J. C., and Nang, L. S., Trav. SOC.Pharm. Montpellier, 25 (2), 111-15 (1965); Chem. Abstr., 65, 86719 (1966). (51) Amormino, V., Ann. Ist. Super.Sanita, 1 (1-6), 380 (1965); Anal. Abstr., 14, 2225 (1967). (52) Amormino, V., Cingolani, E., ibid., 2 (4), 545 (1966); Anal. Abstr., 14, 4977 (1967). (53) Amundson, M. E., Johnson, M. L., Manthey, J. A., J . Pharm. Sci., 54, 684 (1965). (54) Amundson, M. E., Manthey, J. A., ibid., 55 (3), 277 (1966). (55) Analyst, 89, 377 (1964). (56) Ibid., 90, 582 (1965). (57) Ananichev, A. V., Pakalns, D., Med. Prom. S S S R , 20 ( l l ) ,51-3 (1966); Chem. Abstr., 67, 11149On (1967). (58) Ananichev, A. V., Stepanenko, 0. B., Loshkarev, P. M., Ban'kovskii, A. I., Khim.-Farm. Zh., 1 ( l ) ,37-9 (1967); Chem. Abstr., 67, 14875j (1967). (59) Andersons, A., Shimanskaya, M. V., Piperazin, Akad. Nauk Latv., SSR, Inst. Orig. Sin., 1965, 85-114; Chem. Abstr., 66, 43496w (1967). (60) Anderson, R. A., Australian J . Pharm., 47 (555), S26-7 (1966); Chem. Abstr., 67, 76259v (1967). (61) Anderson, R. A., Can. J . Pharm. Sci., 2 (l),25-6 (1967). (62) Andonatos, S., Pharm. Deltion, Epistemonike, Ekdosis, 7 (1-2), 4-9 (1967); Chem. Abstr., 68, 6237h (1968). (63) .Anger, V., Richter, H. E., Mikrocham. Ichnoanal. Acta, 1965 (5-6), pp 1025-27; Anal. Abstr., 14, 2072 (1967). (64) Anisimova, L. G., Tataev, 0. A., Bagdasarov, K. N., Farmatsiya (IclosCOW), 16 (6), 43-7 (1967); Chem. Abstr., 68. 432100 (1968). (65) 'Anmo,A'ri., lqashitake, M., Abe, S., Takashima, Y., Utumi, H., Sato, S., Bitamin, 34 (51, 495-9 (1966); Chem. Abstr., 66, 5727f (1967). \ - - - - ,

,

I

(66) Annino, J. S., Lipson, M., Williams, L. A., Clin. Chem., 11 (lo), 905 (1965). (67) Anouilh, H., Balatre, P., Claeys, Ch., Traisnel, M., Ann. Pharm. Fr., 24 (5), 371-6 (1966); Chem. Abstr., 65, 13456a (1966). (68) Ansorge, S., Bohley, P., Pharmazie, 22 (lo), 574-7 (1967); Chem. Abstr., 68, 33242n (1968). (69) Aoki, M., Iwayama, Y . , hlatsumura, T., Arch. Pract. Pharm., 25 (3), 215 (1965); Anal. Abstr., 13, 7069 (1966). (70) Aoki, M., Iwayama, Y., Matsumura, T., Yakuzaigaku, 25 (3), 49-52 (1965); Chem. Abstr., 65, 3671b (1966). (71) Aoki, M., Kusaka, Y., Arch. Pract. Pharm., 26 ( l ) , 58-60 (1966); Anal. Abstr., 14, 3537 (1967). (72) Aragones-Apodaca, R., Inform. Quim. Anal., 21 (6), 230-3, 224 (1967); Chem. Abstr., 68, 722792 (1968). (73) Archer, A. W., J . Pharm. Pharmacol., 17 (6), 376-8 (1965); Chem. Abstr., 63, 5453b (1965). (74) Ariesan, V., Danciu, F., Suciu, A., Luputiu, G., Ban, C., Arch. Pharm., 299 (3),220-1 (1966); Anal. Abstr., 14, 4234 f1967). (75) Aimasescu, L., Farmacia (Bucharest), 15 (4), 239-44 (1967); Chem. Abstr., 67, 14909y (1967). (76) Armasescu, L., Armasescu, S. I. ibid. (8) vw 455-65: Chem. Abstr.., 67., 93921s (1967j . (77) Asahi, Y., Kasahara, F., Bunseki Kagaku, 14 (7), 614 (1965);Anal. Abstr., 14, 2813 (1967). (78) Ibid., p 619; Anal. Abstr., 14, 2813 (1967). (79) Ascione, P. P., Zagar, J. B., Chrekian, G. P., J . Pharm. Sci., 56 ( l l ) , 1393-5 (1967). (80) Ibid., pp 1396-400. (81) Asoeva, E. Z., Vergeichik, E. N., Nauchn. Dokl. Vysshei Shkoly, Biol. Nauki, 1967 (7), 98-101; Chem. Abstr., 66, 94035y (1967). (82) Ates, O., Amal, H., Istanbul Univ. Eczacilik Fak. Mecm., 2 (2), 82-3 (1966); Chem. Abstr., 66, 118894k (1967). (83) Attal, J., Hendeles, S. M., Engels, J. A., Eik-Nes, K. B., J . Chromatogr., 27 (l),167-71 (1967). (84) Auterhoff, H., Hamacher, H., Arch. Pharm. (Weinheim), 300 (lo), 849-56 (1967); Chem. Abstr., 68, 6207y (1968). (85) Autian, J., M . Mondial Pharm, 9 (4), 316-41 (1966) ; Chem. Abstr., 66,108185r (1967) j _ l _ _

(86) A;igad, G., Bauer, S., Carbohyd. Res., 5 (4), 417-25 (1967). (87) Avioli, L. V., Lee, S. W.,Anal. Biochem., 16 (2), 193 (1966). (88) Awe, W., Hegazy, A., Deut. Apoth., 19 (lo), 4 3 4 4 (1967); Chem. Abstr., 68, 43186m (1968). (89) Babko, A. K., Konyushko, V. S., Zh. Anal. Khim., 21 (4), 486-90 (1966); Chem. Abstr., 65, 2067a (1966). (90) Backe-Hensen, K., Holst, G., Vennerod, A. M., Briseid, K., Acta Pharm. Suecica, 3 (4), 269-72 (1966); Chem. Abstr., 67, 93949n (1967). (91) Backer, E. T., van de Langerijt, J. J. A. M., Pharm. Weekblad, 101 (22), 48996 (1966); Chem. Abstr., 65, 18431h (1966). (92) Baczyk, S., Z . Lebensm.-Unters Forsch., 131 (4),215 (1966);Anal. Abstr., 14, 7658 (1967). (93) ,Baczyk, S., Kachelska, O., Mikrochzm. Acta, 1966 (6), pp 1059-61; Chem. Abstr., 66, 4 9 2 7 4 ~(1967). (94) Baczyk, S., Lempka, A., Baranowska, K., Pr. Zakresu Towarozn.Chem., Wyzsza Szk. Ekon. w Poznaniu Zesz. Nauk., Ser. I , 26, 39-65 (1966); Chem. Abstr., 66, 68895 p (1967). (95) Badawi, M. M., Fayez, M. B. E.,

Planta Med., 15 ( 2 ) , 140-4 (1967); Chem. Abstr., 67, 102832~(1967). (96) Baehler, Br., Pharm. Acta Helv., 42 (6)) 321-7 (1967); Chem. Abstr., 67, 67603a (1967). (97) B a g a t e l l , F. K . , F e r e n d e c i , S . , Laronge, T., J . Lab. Clin. Med., 67 ( l ) , 98 (1966). (98) Baikina, V. M.,Rozenfel'd, G. S., Gromova, -G. L., Frolova, V. I., Chetverikova, L. S., Oparysheva, E. F., Kuzovkov, A. D., Antibiotiki, 11 (8), 695-8 (1966); Chem. Abstr., 65, 16790d (1966). (99) Bailey, F., Holbrook, A., Miller, R. J., J . Pharm. Pharmacol., Suppl. 18, 12-16 (1966). (100) Balatre, P., Guyot, J. C., Traisnel, M., Ann. Pharm. Fr., 24 (6), 425-8 (1966); Chem. Abstr., 66, 5733n (1967). (101) Balatre, P., Guyot-Hermann, A. M., Bull. SOC.Pharm. Lille, 1966 (2)2 pp 83-6; Chem. Abstr., 66, 121880h (1967). (102) Balatre, P., hlusselman-Marsy, D., Traisnel, M., Ann. Pharm. Fr., 25 (9-lo), 649-53 (1967) ; Chem. Abstr., 68, 53300h (1968). (103) Balcar-Skrzydlewska, E., Zalecka, M., Pharmazie, 22 ( 2 ) , 115 (1967); Anal. Abstr., 15, 2899 (1968). (104) Balliu, S., Coroi, S., Baron, O., Farmacia (Bucharest), 15 (6), 353-60 (1967); Chem. Abstr., 67, 84923s (1967). (105) Baloescu, C., Creanga, S., Tudor, M., ibid., 14 ( I ) , 1-7 (1966); Chem. Abstr., 65, 2067d (1966). (106) Baltazar, J., Ferreira Braga, hl. M., Rev. Port. Farm., 16 (3), 169-74 (1966); Chem. Abstr., 67, 67613d (1967). (107) Ibid., 17 ( 2 ) , 109-14 (1967); Chem. Abstr.. 67. 102845e (19671. (108) Bami,' H. L., Indian'J. Pharm., 28 (8)) 216-18 (1966); Chem. Abstr., 66, 5801a (1967). (109) Banaszek, A., Krowicki, K., Zamojski, A., J . Chromatogr., 32 (3), 581-3 (1968). (110) Banaszkiewicz, W., Lutomski, J., Wrocinski, T., Biul. Inst. Roslin Lecznicznych, 10 (2-3), 99 (1964); Chem. Abstr., 63, 4097e (1965). (111) Bandi, G. L., Farmaco, Ed. Prat., 21 (12), 669-76 (1966); Chem. Abstr.; 66, 58866r (1967). (112) Bandi, G. L., Tosi, G. C., ibid., 22 (6), 326-45 (1967); Chem. Abstr., 67, 76327r (1967). (113) Banerjee, B. M.) Tandon, V. B., Agarwal, S. C., Chakravarti, S. C., Indian J . Pharm., 29 ( l o ) , 292 (1967); Chem. Abstr., 67, 1115152 (1967). (114) Banes, D., J . Ass. Ofic. Anal. Chem., 51 (l),152-7 (1968). (115) Barakat, M. Z., Shaker, M., Analyst, 91 (1084), 466-7 (1966). (116) Barakat. M. Z., Shehab, S. K., Afify, N., Microchem. J . , 8 (2), 131 (1964); Anal. Abstr., 12, 5158 (1965). (117) Baranova, I. P., Egorov., X. S., Antibiotiki, 12 ( l ) ,66-9 (1967); Chem. Abstr., 66, 79629f (1967). (118) Barasanova, L. A., Ikramov, L. T., Farmatsiya (Moscow), 16 (6). 64-5 (1967); Chem. Abstr., 68, 43193n (1968). (119) Barbier, F., DeWeerdt, G. A., Acta C o n v . Med. Internae H u n g . , Yrd., Budapest, 1965, pp 629-32; Chem. Abstr., 68, 3323% (1968). (120) Barbiroli, G., Minerva Dietol., 7 (4), 257-8 (1967); Chem. Abstr., 68, 43205s (1968). (121) Bardos, T. J., Kalman, T. I., J . Pharm. Sn'., 55, 606 (1966). (122) Barilari, E. M., Kotler, A,, Arch. Bioquim. Quim. Farm. Tucuman, 12 (1-2), 3-8 (1965); Chem. Abstr., 67, 102825~(1967). (123) Barisic-Paljak, N., Farm. Glasnik, 23 (5), 225-8 (1967); Chem. Abstr., 67, 9403% (1967). VOL. 41, NO. 5, APRIL 1969

221 R

(124) Barnes, M., Parker, M. S., Bradley, T. J., Mfg. Chemist, 37 ( l ) ,47 (1966). (125) Baroncini. D.. Corriere Farm.. 22 (13), 306-7 (1967); Chem. Abstr.,’ 68, 6200r (1968). (126) Barysheva, A. I., Aptechn. Deb, 13 (4), 78-80 (1964); Chem. Abstr., 65, 151579 (1966). (127) Basso, P. D., Cartoni, C. R., Carpi, A., Ann. Ist. Super. Sanita, 3 (3-4), 406-8 (1967); Chem. Abstr., 68, 6233d 11968\. (128) Bastow,R. A., J . Pharm. Pharmawl., 19 (I), 41-4 (1967). (129) Baveja, S. K., AustralasianJ . Pharm., 47 (5641. 5108-13 (1966): Chem. Abstr.. 67.76224e (1967). (130j Baveja,~S.K.,Singla, R. D., Indian J . Pharm., 29 (9), 275-6 (1967); Chem. Abstr., 67, 1027319 (1967). (131) Bayer, I., Herba Hung., 5 (2-3), 81-3 (19661: , . Chem. Abstr.., 68., 43190h (1968). (132) Bayfield, R. F., Clarke, V., Cole, E. R., J . Chromatogr., 26 ( l ) , 132-40 (1967). (133) Bayfield, R. F., Cole, E. R., Anal. Chim. Acta, 34 (2), 193 (1966); Anal. Abstr., 14, 3386 (1967). (134) Bayfield, R. F., Cole, E. R., ChemistAnalyst, 55 (4), 107 (1966). (135) Bazarnii, V. L., Farm. Zh. (Kiev), 22 (2), 31-4 (1967); Chem. Abstr., 67, 47109r (1967). (136) Ibid. (5), pp 84-6; Chem. Abstr., 68, 53224m (1968). (137) Beckett, A. H., htoffat, A. C., Rowland, M., Tucker, G. T., Wilkinson, G. R., J . Chromatogr., 30 (l), 199-202 (1967). (138) Beckett, A. H., Wilkinson, G. R., J . Pharm. Pharmawl., Suppl., 17, 104s (1965). (139) Beckstead, H. D., French, W. N., Truelove, J. F., Can. J. Pharm. Sci., 2 (l),9-13 (1967). (140) Beckstead, H. D., Smith, S. J., J . Pharm. Sci., 56 (3), 390-3 (1967). 1141) Belen’kava. S. L.. Tikhomirov. G. P.: Zavod. Lkb:, 32 (6), 680-1 (1966); Chem. Abstr., 65, 13455.f (1966). 42) Belikov, V. G., Kokoykin-Shcherbak, N. I., Mutsueva, S. Kh., ibid., 33 (9), 1049-52 (1967); Chem. Abstr., 68, 72288b (1968). .43) Belikov, V. G., Kul, I. Ya., Farmatsiya (Moscow), 16 (2), 48-52 (1967); Chem. Abstr., 67, 149060 (1967). .44) Belikov, V. V., Shraiber, M. S., Farm. Zh. (Kiev), 22 (I), 30-6 (1967); Chem. Abstr., 67, 254339 (1967). (145) Bellman, S. W., J . Ass. Ofic. Anal. Chem., 51 (l),164-75 (1968). (146) Bellomonte, G., Ann. Ist. Super. Sanita, 3 (3-4), 403-5 (1967); Chem. Abstr., 68, 24589d (1968). (147) Benmaman, J. D., Sorby, D. L., J . Chromatogr., 20, 607 (1965). (148) Bennett. R. D.. Heftmann., E.., ibid.. 21’ (3), 488-490 (1960). (149) Beral, H., Murea, L., Madgearu, hf., Cuciureanu, E., Acta Pharm. JugoSlav., 15 (3), 77 (1965); Anal. Abstr., 13 6494 (1966). (150) Beral, H., Mureau, L., Madgearu, M., Cuciureanu, E., Wermescher, B., Pharm. Zentralh. Deut., 104 (4), 231-41 (19651: Anal. Abstr.. 13. 4369 (1966). (151) Beral, H., Prodesc;, M., Farmacia (Bucharest), 14 (lo), 603-6 (1966);Chem. Abstr.. 66. 31994u (1967). (152) Beral; H., Stoicescu, V., Ivan, C., Zugravescu, P., ibid., 16 (2), 107-12 (1968); Chem. Abstr., 68, 814422 (1968). (153) Berdnikov, A. I., Aptechn. Delo, 15 (5), 39-46 (1966); Chem. Abstr., 66, 1040722 (1967). (154) Berdnikov, A. I., Tr. Nauchn. Konj. Aspiranotov i Ordinatorov, 1-ya (Pervyz) \ _ _ _ _

.

I

I

~

222 R


Mosk. Med. Znst., MOSWW,1964, pp 134-5; Chem. Abstr., 65, 8677c (1966). (155) Berg, B. H., Acta Pharm. Suecica, 3 209-18 (1966); Chem. Abstr., 65, 8672h (1966). (156) Bergamini, N., Fowst, G., Arzneim.Forsch., 15 @a),951 (1965); Anal. Abstr., 13, 7081 (1966). (157) Berger, J. A., Meyneil, G., Mises Point Chim. Anal. Org. Pharm. Bromatol., 14,l-48 (1965); Chem. Abstr., 65,11317~ (1966). (158) Bernard, J., Ann. Pharm. Fr., 25 (2), 89-99 (1967); Chem. Abstr., 67, 67666y (1967). (159) Bernath, G., Szabo, J. A., Koczka, K., Vinkler, P., Acta Chim. Acad. Sci. Hung., 51 (3), 339-47 (1967); Chem. Abstr., 67, 115846k (1967). (160) Bernshtein, V. N., Litvinenko, A. V., U.S.S.R. patent 185,347 (Aug 13, 1966); Appl. March 12, 1965; Chem. Abstr., 66, 5 8 8 7 8 ~(1967). (161) Berret, R., Gavaudan, A,, Hirtz, J., Ann. Pharm. Fr., 25 (5), 365-9 (1967); Chem. Abstr., 67, 849399 (1967). (162) Berrett, C. R., McNeil, C., Clin. Chem., 12 (7), 399 (1966). (163) Bertorello, hf. M., J . Pharm. Sci., 56 (7). 923-4 11967). (164) ‘Bertschinger, J: P., Utz, F., Pharm. Acta Helv., 41 ( l l ) , 613-621 (1966); Anal. Abstr., 15, 987 (1968). (165) Betts, T. J., J . Pharm. Pharmacol., 17 (8), 520 (1965). (166) Betts, T. J., Holloway, P. J., ibid., SUD.01.. Suppl., 19. 19, 97-102 119671. (1967). (167) Beyer,’K. (167)’ Beyer, K. H., H.,-Zk-A - - - - ,

Martin, R. H., J . Chromatogr., 25 (l), 15-28 (1966). (186) Birkofer, L., Donike, M.,ibid., 26 (l), 270-73 (1967). (187) Bisenbaev, E. M., Farm. Zh. (Kiev), 23 (l),25-8 (1968); Chem. Abstr., 68, 899062 (1968). (188) Biske, V., Knight, H., J . Znst. Petrol., 53 (519), 121-8 (1967). (189) Bitman, S. I., Chausovskii, S. S., A techn. Deb, 15 (3), 65-6 (1966);Chem. A tstr., 65, 86775 (1966). (190) Bjerre, S., Porter, C. J., Clin. Chem., 11 (2), 137 (1965). (191) Blagojevic, Z., Haque, S., Nikolic, K., Acta Pharm. Jugoslav., 17 (2), 11722 (1967); Chem. Abstr., 67, 94046c (1967). -(192) Ibid., pp 123-8; Chem. Abstr., 67, 94032~(1967). (193) Blagojevic, Z., Nikolic, K., Popovic, R., Glasnik Hem. Drustva, Beograd, 31 (3), 171-5 (1966); Chem. Abstr., 68, 89891r (1968). -...~ --,(194) Blagojevic, Z., Popovic, R., Nikolic, K., Acta Pharm. Jugoslav., 16, 145-50 (1966); Chem. Abstr., 66,1082772 (1967). (195) Blagolevic, Z., Radosavljevic, J., ibid., pp 27-30; Chem. Abstr., 65, 571b 11966’1. (196) Blair, H. A. F., Morse, W. I., Brown, J. B., J . Endocrinol., 32 (2), 271 (1965); Anal. Abstr. 13, 5100 (1966). (197) Blake, M. I., Carlstedt, B., J . Pharm. Sci., 55 (12), 1462 (1966). (198) Blank, R. H., Hausmann, W. K., Holmlund, C. E., Bohonos, N., J . Chromatogr., 17 (3), 528-531 (1965). (199) Blank, R. H., Holmlund, C. E., Anal. Biochem., 13 (2), 360 (1965). (200) Blattna, J., Manouskova, J., Prumysl Potrawin, 18 (4), 207-10 (1967); Chem. Abstr., 67, 572755 (1967). (201) Blau, K., Darbre, A., Chim. Anal. (Paris), 47 (12), 631-3 (1965); Chem. Abstr., 65, 3951c (1966). (202) Blazek, J., Cesk. Farm., 15 (4), 2005 (1966); Chem. Abstr., 65,8677h (1966). (203) Ibid. (6), pp 314-16; Chem. Abstr., 65, 19933c (1966). (204) Ibid. (9), pp 478-82; Chem. Abstr., 66, 68893m (1967). (205) Blazek, J., Pharmazie, 22 (3), 12946 (1967); Chem. Abstr., 67, 39934r (1967). (206) Blazek, J., Hronikova, M., Cesk. Farm., 16 ( l ) ,41-2 (1967); Chem. Abstr., 66, ll8886j (1967). (207) Blazek, J., Kracmar, J., Pinkasova, M., ibid. (9), pp 437-46; Chem. Abstr., 68, 814499 (1968). (208) Blazek, J., Mares, V., ibid., 15 (7), 349-55 (1966); Chem. Abstr., 66, 222665 (1967). (209) Biazek, J., Spinkova, V., Steijkal, E., Anales Farm. Hos ., 10 (20), 7 4 0 (1967)j Chem. Abstr., 36373w (1967) (210) Blinov, N. O., Antibiotzki, 12 (7); 626-38 (1967):Chem. Abstr.,. 67,120201~ , (1967). (211) Blondin, G. A,, Kulkarni, B. D., John, J. P., Van Aller, R. T., Russell, P. T., Nes, W. R., ANAL.CHEM.,39 (l), 36-40 (1967). (212) Blunden, G.,Hardman, R., Morrison, J. C., J . Pharm. Sci., 56 (8), 948-50 I--

I -

\ - -

d,

(1967). \ _ _ _,..

(213) Bobarevic, B., Dinic, M., Glasnik Drustva Hemicara Technol. NR Bosne Hercegowzne, 13-14,99-103 (1965); Chem. Abstr., 65, 12062c (1966). (214) Bodnar, I. M., Farm. Zh. (Kiev), 21 (4), 37-9 (1966); Chem. Abstr., 65, 19932h (1966). (215) Bogan, J., Smith, H. Forensic Sci. sac. J.,7 (1),37 (1967);Anal ~ b s t r . 15, , 2787 (1968). (216) Bogs, H. U., Pharm. Zentralh. Deut., 104 (8), 554 (1965); Anal. Abstr., 13, 7077 (1966).

(217) Ibid., 106 (l),7-8 (1967); Chem. Abstr., 66, 68978t (1967). (218) Bohacek, J., Singh, C., Anal. Biochem., 15 (l),1-7 (lg66). 1219) Bohinc. P.. Farm. Vestnik (Liubl‘ jaha), 17 ‘(1-4), 8-12, (1966); ‘Clem. Abstr., 66, 22220m (1967). (220) Zbid., 18 (1-4), 9-20, (1967); Chem. Abstr., 67, 120199b (1967). (221) Bohme, H., Kreutzig, L., Arzneim.Forsch., 16 (2), 212 (1966); Anal. Abstr., 14, 3509 (1967). (222) Bohonos, N., Piersma, H. D., Bio. Sci.. 16 110). 706-14 (1966’1. (223) ’Bohrmann, H., Stahl,’ E., Mitsuhashi, H., Chem. Pharm. Bull. (Tokyo), 15 (lo), 1606-8 (1967); Chem. Abstr., 68, 6231b (1968). (224) Boichinov, A., Akhtardzhiev, Khr., Kolev, Dim., Farmatsiya (Sofia), 14 (5), 12-16 (1964); Chem. Abstr., 66, 492731 119671. (225) -Boichinov, Khr., ibid., 16 (4), 34-9 (1966); Chem. Abstr., 66, 58876u (1967). (226) Zbid., 17 (21, 16-20 (1967); Chem. Abstr., 67, 84947h (1967). (227) Biochinov, Khr., Cholakova, G., ibid.. 16 13). 11-15 11966): Chem. Abstr.. 65, 184298 (1966). (228) Bokowski, D. L., Hammond, S. E., U.S. At. Energy Comm., Dept. RFP-510 (1965); Anal. Abstr., 13, 6363 (1966). (229) Bol’shakova, L. O., Belen’kii, B. G., Pokrovskii, E. I., Antibiotiki, 12 (lo), 884-7 (1967); Chem. Abstr., 68, 16178d (1968). (230) Bol’shakova, T. D., Tr. Nouoi Apparature Metodikam, Pervoi Mosk. Med. Znst., 1965 (3), pp 56-62; Referat. Zh., Biol. Khim., 30F, 1966 (3), Abstr. No. 3Fl52; Anal. Abstr., 13, 5029 (1966). (231) Bolt, A. G., Forrest, I. S., Serra, M. T., J . Pharm. Sci., 55, 1205 (1966). (232) Bombardelli, E., Pitoterapia, 36 (3), 72-6 (1965); Chem. Abstr., 65, 6997e (1966). (233) Bomstein, J., Evans, W. G., ANAL. CHEM.,37, 576 (1965). (234) Bomstein, J., Shepp, J. M., Dawson, S. T., Blaedel, W. J., J . Pharm., Sci., 55 11). 94-8 11966). (235)’ Bonati, A., Bacchini, M., Fitoterapia, 37 ( l ) , 24-9 (1966); Chem. Abstr., 65, 15159s (1966). (236) Bondarenko, K. V., Zh. Obshch. Khim., 37 (a), 332-5 (1967); Chem. Abstr., 67, 148809 (1967). (237) Bonino, R. C., Dobrecky, J., Rev. Assoc. Bioquim. Arg., 31 (162), 18-22 (1966); Chem. Abstr., 66, 22280f (1967). (238) Ibid. (167),pp 184-90; Chem. Abstr., 67,111470.f (1967). (239) Bonnard, J., Farmaco, Ed. Prat., 22 (61, 305-25 (1967); Chem. Abstr., 67, 76326~(1967). (240) Bonnard,’J., Pharm. Belg., 21 (7-8), 363-74 (1966); Chem. Abstr., 66, 1 4 0 6 0 ~ (1967). (241) rBbnnichsen, R., Maehly, A. C., Forenszc Sci. SOC.J., 5 (4), 201 (1965). (242) Boon, P. F. G.. Sudds. W.. J . Pharm. Pharmacol., Suppl. 19, 88-92 (1967). (243) Borkowski, B., Sobiczewska, M., Acta Polon. Pharm., 22 (6) 529 (1965); Anal. Abstr., 14, 2790 (1967); (244) Bormann, G., Pharmazze, 21 (7), 407-17 (1966); Chem. Abstr., 65, 18430e (1966). (245) Borowiecka, B., a s s . Pharm., 17 (3), 313-18 (1965); Chem. Abstr., 65, 5711 (1966). (246) Borowski, E., Chmara, H., JarecaekMorawska, E., Biochim. Biophys. Acta, 130 (2), 560-3 (1966); Chem. Abstr., 66, 985281, (1967). (247) Bbrs, Gh., Popa, I., Voicu, A., Farmacia (Bucharest), 15 ( l ) , 7-12 (1967); Chem. Abstr., 66, 985229 (1967). (248) Ibid. (9), pp 521-4; Chem. Abstr., 67, 1 0 2 8 2 3 ~(1967). ’

(249) Borysewicz, S., Acta Polon. Pharm., 23 (2), 187 (1966); Anal. Abstr., 14, 4395 (1967). (250) Bose, B. C., Vijayvargiya, R., Indian J . Pharm., 28 (12), 328-30 (1966); Chem. Abstr., 66, 1083079 (1967). (251) Bose, S., Dey, G. C., Bose, D. K., Zbid., 29 (9), 266-8 (1967); Chem. Abstr., 67, 111508~(1967). (252) Bosche, W., Pharm. Tijdschr. Belg., 44 (4), 65-9 (1967); Chem. Abstr., 67, 67620d (1967). (253) Boughton, 0. D., Bryant, R., Ludwig, W. J., Timma, D. L., J . Pharm. Sn’., 55 (9), 951-5 (1966). (254) Bourdon, R., Mises Point Chim. Anal. Org. Pharm. Bromatol., 1967 (15), pp 1-41; Chem. Abstr., 67,363742 (1967). (255) Bouw. P. S.. Suara Pharm. Madialah. 8 ’(I), 7-12 (1965); Chem. Absti, 63; 409.5e (196.5). (256)Bowman, P. B., West, W. E., J . Pharm. Sci., 57 (3), 470-3 (1968). (257) Bozsai, G., Kelemen-Kuettel, I., Monsonyi, AI., Gyogyszereszet, 11 (4), 142-6 (1967); Chem. Abstr., 67, 848469 (19671. (258) Bracey, A., Garrett, L., Weiss, P. J., J . Pharm. Sci., 55 (lo), 1113~15(1966). (259) Bracey, A., Selzer, G., zbzd., 57 (3), 464-6 (1968). (260) Bradham, L. S., Catsimpoolas, N., Wood. J. L.. Anal Biochem.. 11 (21. 230 , (1965). (261) Bradley, T. J., Parker, M. S., Barnes, M., J . Hosp. Pharm., 24 (l), 17-21 (1967) ,- . ,. (262) Braga, A., Gabriel, S. J., Carazzoni, E. P., Gotlieb, 0. R., Lyra, F. D. A,, Anais. Acad. Brasil. Cienc., 39 (2), 253-4 (1967); Chem. Abstr., 68, 62632~(1968). (263) Bramlett, C. L., J. Ass. O$C. Anal. Chem., 49 (4),857-9 (1966). (264) Ibid., 50 (3), 682-4 (1967). (265) Brammer, K. W.,Hemson, L. J., J . Chromatogr., 19 (2), 456-8 (1965). (266’1 Brandstatter-Kuhnert. hl.. Juneer. E.; Kofler, A., Microchem.’J., 9 (2), “li (1965); Anal. Abstr., 13, 5814 (1966). (267) Brandstaetter, M. K., Kofler, A., Vlachopoulos, A., Sci. Pharm., 35 (2), 96-116 (1967): , . Chem. Abstr.. 67. 848880 (1967). (268) Brandys, J., Diss. Phamn. Pharmawl., 18 (3), 319 (1966); Chem. Abstr., 66, 22276j (1967). (269) Brantner, A., Vamos, J., Vegh, A., Simonyi, I., Acta Pharm. Hung., 37 (2), 49-54 (1967); Chem. Abstr., 66, 108313f (1967). (270) Brantner, H., Sci. Pharm., 35 (3), 210-14 (1967); Chem. Abstr., 68, 6156s \ - - - - I

I

I ,

--

I

,

f19681. \ - - - - I -

(271) Braum, J., J . Mondial Pharm., 9 (3), 177-90 (1966); Chem. Abstr., 66, 68953f (1967). (272) Brazhnikova, M. G., Lomakina, N. ,Y., Pokras, L. S., Tolstykh, I. V., Antibaotiki, 12 (2), 129-32 (1967); Anal. Abstr., 15, 2905 (1968). (273) Brazhnikova, M. G., Ponomarenko, V. I., Kovsharova, I. N., Kruglyak, E. B., Proshlyakova, V. V., ibid., 13 (2), 99-102 (1968) ; Chem. Abstr., 68, 89890q (1968). (274) Breinlich, J., Deut. Apotheker-Ztg., 107 (49), 1795-8 (1967); Chem. Abstr., 68, 53305p (1968). (275) Breinlich, J., Pharm. Ztg., Ver. Apotheker-Zt ., 111 (50), 1866-71 (1966); Chem. Atstr.. 66. 79642e (1967). (276) Zbid., 109, ’1744-8 (1964); Chem. Abstr., 65, 15162e (1966). (277) Breithaupt, PI., Hahn, H., Finsching, P., Deut. Apotheker-Ztg., 105, 1072-3 (1965); Chem. Abstr., 66,407379 (1967). (278) Breithurd, P., Puisieux, F., Le Hir, A., Ann. Pharm. Fr., 24 (3), 191-9 (1966); Chem. Abstr., 65, 8572d (1966).

(279) Breuer, K., Pharmazie, 22 (l),3-13 (1967); Chem. Abstr., 66,108265s (1967). (280) Broadley, K. J., Roberts, D. J., J. Pharm. Pharmawl., 18 (3), 182 (1966). (281) Brochmann-Hanssen, E., Planta Med., Suppl., 1967, pp 44-7; Chem. Abstr., 68, 6199s (1968). (282) Brochmann-Hanssen, E., Nielsen, B., Utzinger, G. E., J . Pharm. Sci., 54 (lo), 1531 (1965). (283) Brochmann-Hanssen, E., Schmid, P., Benmaman, J. D., ibid. (5), pp 783-4. (284) Brochmann-Hanssen, E., Svendsen, A. B., Pharmazie, 20 ( l o ) , 591 (1965); Anal. Abstr., 14, 963 (1967). (285) Broda, B., Farm. Polska, 23 (2), 119 (1967); Anal. Abstr., 15, 2231 (1968). (286) Broda, B., Wojciechowska, B., Dombrowicz, E., Diss. Pharm. Pharmacol., 18 ( 5 ) , 501-4 (1966); Chem. Abstr., 67, 84899u (1967). (287) Brodasky, T. F., J . Gas Chromatogr., 5 (6), 311-18 (1967). (288) Brode, E., Arzneim-Forsch., 17 ( l ) , 103-8 (1967); Chem. Abstr., 67, 56809 (1967). (289) Bioich, J. R., Mayo, M. M,, Dal Cortivo, L. A., J . Chromatogr., 33 (3-4), 526-9 (1968). (290) Brojo, A. P., Leitao, E. F., Nobre Sequeira, M. L., Rev. Port. Farm., 16 (4), 417-19 (1966) ; Chem. Abstr., 66, 98465r (1967). (291) Brown, E. G., Mangat, B. S., Anal. Biochem., 15 (3), 542-4 (1966). (292) Brown, I. R., Dyer, A. E., Elowe, I. N.. Stauffer. I. E.. Walker. G. C.. Can. J . Pharm. Sd,1 (I), 22-6 ’(1966j. (293) Bruja, N. Z., Rev. Chim. (Bucharest), 17 (6), 359-60 (1966); Chem. Abstr., 65, 15163c (1966). (294) Ibid. (ll),pp 692-3; Chem. Abstr., 66, 6 8 9 9 3 ~(1967). (295) Bruschi, F., Boll. Chim. Farm., 105 (3), 237-40 (1966); Chem. Abstr., 65, 57Oe (1966). (296) Brustj’H. F., Down Earth, 22 (3), 21-2 (1966); Chem. Abstr., 66, 68865d (1967). (297) Brustier, V., Bourbon, P., Amselem, A., Achor, G., Casabonne, M., Ferrand, J . C.. Ann. Pharm. Fr.. 24 (1). 51-6 (1966); Chem. Abstr., 65, 36729 (1966). (298) Bryant, R., Mantle, D. E., Yoder. D. S., J . Pharm. Sci., 55 (7), 733-4 (1966). (299) Brzezinska, D., DziedzianowiczWierzbicka, W.,Farm. Polska, 22 (6), 416-18 (1966); Chem. Abstr., 66, 49271r 11967). (300) Bizezinska,D.,Pliszczynska, J.,ibid., pp 439-40; Chem. Abstr., 66, 49267u (1967). (301) Bubon, N. T., Aptechn. Delo, 15 (2), 73-7 (1966); Chem. Abstr., 65, 569b (1966). (302) Bubon, N. T., Yashchenko, V. K., ibid. (5), pp 46-9; Chem. Abstr., 66, 222372 (1967). (303) Budvari, Z., Khin, L., Szasz, G., Vegh, A., Acta Pharm. Hung., 37 (3), 97-107 (1967): Chem. Abstr.., 67.. 57273d (1967). (304) Buechi, J., Pharm. Acta Helv. 42 ( 5 ) , 257-64 (1967); Chem. Abstr., 67 253842 (1967). (305) Ibid. (12), pp 673-716; Chem. Abstr., 6 8 , 3 3 1 1 5 ~(1968). (306) Buechi, J., Fresen, J. A., ibid., 41 (lo), 551-74 (1966); Chem. Abstr., 65, 19928d (1966). (307) Buechi. J. Moos R. von ibid. (3). p 142; Anal. Abstr., 14, 4231 (1967). (308) B u e t t n e r , H . , P o r t w i c h , F . . Arzneim.-Forsch., 17 ( i )809-12 , (1967); Chem. Abstr.. 67. 93947k (1967). (309) Bukowska, H.;-Goluckii Z., Chem. Anal. (Warsaw) 11 (2), 291-8 (1966); Chem. Abstr., 65, 2670d (1966). ”

VOL. 41, NO. 5, APRIL 1969

223 R

(310) Bukreeva, T. V., Zh. Prikl. Khim., 39 (7), 1653-4 (1966); Chem. Abstr., 65, 13027b (1966). (311) Bulant, V., Czechoslovakian patent (April 15, 1966); Appl. Dec. 4, 1964; Chem. Abstr., 66, 22297s (1967). (312) Burger, E., Arch. Toxikol., 21 (2), 121 (1965);Anal. Abstr., 13,5796 (1966). (313) Burghardt, H., Jaeger, H., Stackelberg, M. von, J . Electroanal. Chem. Interfacial Electrochem., 17 (1-2), 191-9 (1968); Chem. Abstr. 68, 81447e (1968). (314) Buri, P., Pharm. Acta Helv., 42 (6), 344-9 (1967); Chem. Abstr., 67 6734n (1967). (315) Burianek, J., Cesk. Farm., 15 (3), 130-3 (1966); Chem. Abstr., 65, 2071a (1966). (316) Burlinson, H., Symposium, “Identification of Drugs and Poisons,” London, March 1965, Pharmaceutical Societv of Great Britain, pp 9-14; Anal. Abstr.; 13, 3360 (1966). (317) Bussmann, G., Haenni, W., Pharm. Acta Helv., 42 ( I ) ,41-53 (1967); Chem. Abstr., 66, 69005k (1967). (318) Butkiewicz, K., Kowalczyk, E., Chem. Anal. (Warsaw), 11 (6), 1209-13 (1966);Chem. Abstr., 66,108304d (1967). (319) Ibid., 12 ( l ) ,67-70 (1967); Chem. Abstr., 67, 4 7 1 2 8 ~(1967). (320) Butler, C. G., Kaushik, D. S., Maxwell, J., Stell, J. G. P., J. Mondial Pharm., 10 (4), 359-64 (1967); Chem. Abstr., 68, 8989851 (1968). (321) Calafeteanu, I., Dumitrescu, E., Grintescu, P., Rev. Chim. (Bucharest), 16 (l),41 (1965); Anal. Abstr., 13, 3786 (1966). (322) Calmanovici, B., h i d . , 17 (6), 374-5 (1966); Chem. Abstr., 65, 15154f (1966). (323) Calvin, H. I., Roberts, K. D., Weiss, C., Bandi, L., Cos, J. J., Lieberman, S., Anal. Biochem., 15 (3), 426 (1966). (324) Camellini, A., Schiatti, G., Boll. Chim. Farm., 106 (7), 463-6 (1967); Chem. Abstr., 68, 16193e (1968). (325) Canbaeck, T., J . Mondial Pharm., 10 ( l ) , 55-7 (1967); Chem. Abstr., 68, 6202t (1968). (326) Capper, K. R., ibid., 9 (4), 305-15 (1966); Chem. Abstr., 66,108184q (1967). (327) Cardini, C., Quercia, V., Calo, 8., Boll. Chim. Farm., 106 (4), 215-22 (1967); Chem. Abstr., 67, 84928c (1967). (328) Ibid. (7), pp 452-8; Chem. Abstr., 67. 111494s (1967). (329) Ibid., pp 459-62; Chem. Abstr., 67, 11149% - - -.-. (19671. -(330) Carlier, A., Puisieux, F., Le Hir, A., Ann. Pharm. Fr., 25 (6), 473-80 (1967); Chem. Abstr., 67, 11148% (1967). (331) Carlier, A,, Puisieux, F., W e t , C., Le Hir. A.. ibid.. 24 (5). 349-56 (19661: Chem. hbstr., 65, 15155g (1966). (332) Carlson, L. A., Clin. Chim. Acta, 13 (3), 349 (1966); Anal. Abstr., 14, 4172 (1967). (333) Cameras, L., Alonso, M. G., J . Chromatogr., 29 (2), 388-90 (1967). (334) Carstensen, J. T., Aron, E. S., Spera, D. C., Vance, J. J., J . Pharm. Sn’., 55 (6), 561-7 (1966). (335) Carvajal, C: R., Garcia, N. RI., Rev. Real Acad. Czenc. Exact. Fis. Nut. Madrid, 60 (4), 601-13 (1966); Chem. Abstr.. 67. 76357a (1967). (336) Casaiano, A., Corriere Farm., 21 (17), 415-16 (1966); Chem. Abstr., 67, 5736n (1967). (337) Ibid. (19), pp 473-4; Chem. Abstr., 66, 98523h (1967). (338) Casellato, F., Casu, B., Nardi, D., Boll. Chim. Farm., 105 (12), 880-90 (1966): Chem. Abstr.. 67. 14904t (1967). (339) Casilli, I., Ragni,’G.,‘ibid., 104, 4327 (1965);Chem. Abstr., 67,14878n (1967). (340) Casini, F., ibid. (3), pp 177-81; Chem. Abstr., 63, 4094b (1965). \ - -

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I


(341) Castel, J., Bourrely, Cl., Trav. SOC. Pharm. Montpellier, 25 (3), 185-90 (1966); Chem. Abstr., 65, 36669 (1966). (342) Castel, J., Vaillefont, M.F., ibid., 26 (2), 127-34 (1966); Chem. Abstr., 67, 3637% (1967).

(344) Castren, E., Fa; (12), 408-16 (1966); Chem. Abstr., ‘66, 7963% (1967). (345) Casy, A.’F., J . Pharm. Sci., 56 (9), 1049-63 (1967). (346) Cavaco, A. C. C., Falcao, R. F., Rev. Port. Farm., 16 (l), 1-8 (1966); Chem. Abstr., 65, 3675b (1966). (347) Cavicchi, G. S., Quaglio, R l . P., Braghiroli, A., Boll. Chim. Farm., 105 (9), 670-4 (1966); Chem. Abstr., 66, 22296r (1967). (348) Cavina, G., Moretti, G., J . Chromatogr., 22 (l), 41 (1966). (349) Cawley, L. P., Rlusser, B. O., Faucette, W., Beckloff, S., Learned, H., Clin. Chem., 11 (ll),1009 (1965). (350) Ceglarski, R., Regosz, A., Farm. Polska, 23 (5-6), 437-9 (1967); Chem. Abstr., 67, 120212a (1967). (351) Ceia, hl., Lima, hl. >I., Baptista, A. M.. Arauiv. Patol. (Lisbon). 37 (2-3). 75-9 ‘(1965); Chem. Abstr., ’65 2068g (1966). (352) Celeste, A. C., Polito, 11. V., J. Ass. Ofic. Anal. Chem., 49 (3), 541-5 (1966). (353) Celsi, S. A., Sarrailh, P. O., Ann. Pharm. Fr., 23 (12), 775-80 (1965); Chem. Abstr., 65, 572b (1966). (354) Cerdas, J., Carlier, A., Puisieux, F., Le Hir, A., ibid., 25 (7-8), 553-9 (1967) ; Chem. Abstr., 68, 6242f (1968). (355) Chafetz, L., Elefant, X,Amin, P. R.. J. Pharm. Sci.. 56 (111, 1528-9 (1967). (356) Chafetz, L., Gaglia, C. A., ibid., 55 (81. 8.5476 - - - - (1966). \-,I

\ - - - - ,

(357) Ibid., 56 (12), 1681-2 (1967). (358) Chaigneau, M., Chastagnier, M., Ann. Pharm. Fr., 23 (4), 259 (1965); Anal. Abstr., 13, 4408 (1966). (359) Ibid., 25 (6), 463-6 (1967): Chem. Abstr.. 67. 763542 11967). (360) Chakiaborty, AI., Dutta, S. K., J. Inst. Chem. (India), 39 (6), 288-91 (1967); Chem. Abstr., 68, 43203q (1968). (361) Chalmers, A. H., Culvenor, C. C. J., Smith, L. W., J. Chromatour., 20 (2). 270 (1965). (362) Chandra, D., Sharma, V. N.,klital, R. L., Chemzst-Analyst, 56 (4), 100 (1 967). ,. \ _ _ _ _

(363) Chandra, S., Yadova, K. L., Talanta, 15 (3), 349-52 (1968). (364) C h a n d r a , U . , P a n d e y , P . , “LABDEV” (KanDur. India) 5 (4). 333-4 (1967); Chem. Abstr., 68, 16191c (1968). --, (365) Chang, W. C., Yao Hsueh Hsueh Pao, 13 (2), 155 (1966) ; Chem. Abstr., 65, 53058 (1966). (366) Chaplinskaya, R l . G., Dolzhanskaya, R. N., Farmatsiya (Moscow), 16 (2), 20-3 (1967): Chem. Abstr.,, 67,. 148681’ (1967). (367) Charamza, O., Cesk. Farm., 15 (3), 148-9 (1966); Chem. Abstr., 65, 2066b (1966). (368) Charles, R. L., Knevel, A. AI., J . Pharm. Sci., 54 (ll), 1678 (1965). (369) Chatten, L. G., Napper, 8.C., Can. J. Pharm. Sci., 1 (l), 30-4 (1966). (370) Chatten, L. G., Napper, A. C., Barry, P. J., J. Pharm. Sci., 56 (7), 834-8 (1967). (371) Chatten, L. G., Racz, W.J., ibid., 57 (l),137-42 (1968). (372) Chausovskii, S. S., Brombergiene, M., Farmatsiya (Moscow), 16 (4), 59-61 (1967);Chem. Abstr., 67,1028172 (1967). \ - -

(373) Chemerisskaya, A. A,, Tubina, I. S., Kuzovkova, R. I., Shvidko, R. I., Dolgopolov, V. D., Khim.-Farm. Zh., l (7), 46-7 (1967); Chem. Abstr., 68, 6235f (1968’1. (374) Ch’en, C. C., Chang, S. L., Tai, J. L., Yao Hsueh Hsueh Pao, 13 (2), 131-7 (1966); Chem. Abstr., 65, 8673c (1966). (375) Chernyakhover, S. I., Runova, V. F., Lab. Delo, 1966 (9), p 568; Chem. Abstr., 65, 19930f (1966). (376) Chichiro, V. E., Sb. Nauchn. Tr. Tsentr. Aptechn. Nauchn.-Issled. Inst., 7-8, 119-24 (1966); Chem. Abstr., 68, 53291f (1968). (377) Chichiro, V. E., Ponomareva, Z. P., Aptechn. Delo, 15 ( 5 ) , 76-82 (1966); Chem. Abstr., 66, 22219t (1967). (378) Itrid. (6), pp 65-9; Chem. Abstr., 66, 689671, (1967). (379) Chichiro, V. E., Ponomareva, Z. P., Farmatsiya (Moscow), 16 (l), 78-83 (1967); Chem. Abstr., 66, 98504c (1967). 1380) Chin. T. F., Lach. J. L.. J . Pharm. Sb., 54, 1550 (1965). ’ (381) Chladek, K., Ruzickova, J., Baloun, J., Farm. Obzor, 35 (9), 408-13 (1966); Anal. Abstr., 15, 1002 (1968). (382) Chodakowski, A. AI., Jeske, S., Acta Polon. Pharm., 23 (I), 47-9 (1966); Chem. Abstr., 65 2066e (1966). (383) Chodakowsk;, A. M.,Mosiniak, T., ibid., 24 (5), 511-13 11967); Chem. Abstr., 68, 43196q (1968). (384) Chou, H. S., Ku, C. Y., Chin, C. L., Ch’en, C. Y., Hu, C. L., Lo, 6. L., Chao, H. K., Yao Hsueh Hsueh Pao, 13 (4), 280-5 (1966); Chem. Abatr., 65, 8673a (1966). (385) Chou, T. C., Lin, H. H., J . Chromatogr., 27 (l),307-10 (1967). (386) Choulis, N. H., Hem. Hron., A , 30 (41, 52 (1965); Anal. Abstr., 13, 6484 (1966). (387) Choulis, K. H., J . Chromatogr., 30 (2). 618-19 11967). (388i’ Cho (388j’Choulis, N. H., J . Pharm. Sci., 56 (2), i96-9 (2j, 196-9 (1967). (389) Christenson, I., Acta Pharm. Suecica, 5 (I), 23-36 (1968); Chem. Abstr., 68, 899042 (1968). (390) Ciampa, G., Grieco, C., Silipo, C., Farmaco. Ed. Prat.. 22 (2). 70-95 (1967): Chem. Abstr.. 66. 98505d’?1967). (391) Cieslak, I., Biiszko, N., MakarowskaPlociennik, Z., Antibiotiki, 12 ( 5 ) , 41014 (1967); Chem. Abstr., 67, 762409 (1967). (392) Cieszynski, T., Diss. Pharm. Pharm a d 19 (5), 563-6 (1967); Chem. Abstr., 68, 43221u (1968). (393) Cieezynski, T., hlasiakowski, J., Borowska, Rl., Farm. Polska, 22 (lo), 735-7 (1966); Chem. Abstr., 67, 76359c (1 \ _967) _ _,.. (394) Cima, L., Levorato, C., Mantovan, R., Farmaco, Ed. Prat., 21 ( 5 ) , 244-74 (1966); Chem. Abstr., 65, 8674h (1966). (395) Ciogolea,Gh., Ealoescu, C., Creanga, S., Petroniu, L., Farmacia (Bucharest), 15 ( 5 ) , 257-62 (1967); Chem. Absfr., 67, \ -

~

(396) C

Chem.. Abdr., 64, 118893j (lY67). (398) Ciulei, I., zbid., (lo), pp 585-90; Chem. Abstr., 68, 24570r (1968). 1399) ~, Clarke. D. D.. Wilk. S.. Gitlow. S. ‘ E,, E., J . Gas Chromaiogr., 4’(8),’310 (1966). (400) Clarke, E. G. C., Forensic Sci. Sa. SOC. .T.. J., 7 (1). (l), 31 (1967). (401) 46-50; Chem. Abstr., 67, (401j Ibid., pp -46-50; 120210y (1967). (402) Clarke, E. G. C., Symposium, “Identification of Drugs and Poisons,” London, March 1965, Pharmaceutical \ - -

\-,?

~~

Society of Great Britain, pp 47-56; Anal. Abstr., 13, 3360 (1966). (403) Clarke, V., Cole, E. R., J . Chromatogr., 24 (l), 259-61 (1966). (404) Clements, J. A., Forbes, St. J., Olliff, C. J., Rogers, A. R., J . Pharm. Pharmawl., Suppl., 19, 103-4 (1967). (405) Clugston, D. M.,MacLean, D. B., Manske, R. H. F., Can. J . Chem., 45 (l),39-47 (1967). (406) Coassini-Lokar, L., Univ. Studi Trieste, Fac. Econ. Com., Ist. Merceol., 1965 (25), 24pp; Anal. Abstr., 15,236 (1968). 1407) Ibid., 1966 (27), 19pp.; Anal. Abstr., 15, 236 (1968). (408) Cohen, V., J . Chromatogr., 23 (3), 446-56 (1966). (409) Cole, B. R., Leadbeater, L., J . Pharm. Pharmucol., 20 (l),48-53 (1968). (410) Collier, H. B., Duchon, G., Anal. Biochem., 15 (2). 367-8 (1966). (411) Collings, S., Sinai-., R., J . Ass. Public Analysts, 4 (3), 59-60 (1966). (412) Colombatti, V.,Farmaco, Ed. Prat., 20 (12), 593-5 (1965); Anal. Abstr., 14, 2800 (1967). (413) Comer, J. P., Comer, I., J . Pharm. SCi., 56 (4), 413-36 (1967). (414) Comer, J. P., Hartsaw, P., Steven~011,C. E.! ibid., 57 ( l ) , 147-51 (1968). (415) Conklin, J. D., Hollifield, R. D., Clin. Chem., 12 (lo), 690 (1966). (416) Constantine, G. H., Jr., Vitek, 11. R., Sheth, K., Catalfomo, P., Sciuchetti, L. A., J . Pharm. Sci., 55 (9), 982-4 (1966). (417) Constanlinescu, E., Albulescu, D., Nichiforescu, E., Chiliment, M.,Mitea, S., Farmucia (Bucharest), 16 i l ) , 21-8 (1968); Chem. Abstr., 68, 627508 (1968). (418) Conway, P. J., Diss. Abstr., B , 27 (91, 3031-2 11967); Univ. Microfilma (Ann Arbor, Mich.), Order S o . 6612,2780, 225 pp. (419) Conway, IT. D., Piontek, R. W., Shekosky, J. 31..J . Chromatogr., 27 (I), 317 (1967). (420) Cook, G. B., Galatzeanu, I., Radiochem C‘onf., Abstr. Pap. Bratislava, 1966, 54-5: Chem. Abstr., 68, 33157p (1968). (421) Cooper, J., Lez Sci., 3 (3), 178-93 (1966); Chem. Abstr., 66, 5713p (1967). (422) Cordes, G., Arch. Pharm., 299 ( 5 ) , 418-22 (1966); Chem. Abstr., 65, 3672c (1966). (423) Cordiano, A., Corriere Farm., 21 (IT), 446-7 (1966); Chem. Abstr., 66, 118874d (1967). (424) Corn; hf., Berberich, R., Clin. Chem., 13 (2), 126 (1967). (425) Cornelius, J., Yang, H. Y., J . Gas Chromatogr., 5 (6), 327-8 (1967) ; Chem. Abstr., 65, 67648~’ (1967). (426) Cosi, G., Bichi. G.. Farmaco. Ed. Prat., 22 (6), 346-51 ’ (1967); Chem. Abstr.. 67. 76338v 11967). (427) Cbsi, G., Pacciani, AI., ibid., 21 (7), 380-6, (1966); Chem. Abstr., 65, l5160d ilRfi6) ~_.__,_

(428) Costopanagiotis, A., Budzikiewiez, H., Monatsh. Chem., 96 (6), 1800 (1965); Anal. Abstr., 13, 7086 (1966). (429) Cotty, V. F., Ederma, H. >I., J. Pharm. Sci., 55 (8), 837 (1966). (430) ‘‘ ‘Cou,l,ter Counter’ Industrial Bibliography, Coulter Electronics, Ltd., Dunstable, Beds., England, 1966. 1431) Court, W.E., Can. J . Pharm. Sci., 1 (2), 76-9 (1966). (43’2) Courtois, J. E., Diep, B. K., Ann. Pharm. Fr., 23 (12), 705-13 (1965); Chem. Abstr., 65, 572d (1966). (433) Coutts, R. T., Storey, S. I., Can. J . Pharm. Sci., 1 (l),38-41 (1966). (4343 Coutts, R. T., Storey, S. J., 2 ( I ) , 22-4 11067). (435) Covello, ?*I.,Pixopo, E., Rend. Accad. Sci. Fis. Mat. (Soc. Nazl. Sci. Napoli) 32,219-32 (1965); Chem. Abstr., 67, 5707d (19G7). ~~

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(436) Covello, M., Schettino, O., Boll. Chim. Farm., 106,791-801 (1967); Chem. Abstr., 68, 89900t (1968). (437) Covello, M., Schettino, O., Farmaw, Ed. Prat.. 20 112). 581 (1965): Anal. Abstr., 14; 2797 (1967). (438) Cox, F. H., Pinxteren, J. A. C. van, Pharm. Weekblad., 101 (16), 361-6 (1966); Chem. Abstr., 67, 763562 (1967). (439) Crabtree, A. N., McGill, A. E. J., Mikrochim. Acta, 1967 (l), 85-7; Chem. Abstr., 66, 52021q (1966). (440) Crawhall, J. C., Thompson, C. J., Bradley, K. H., Anal. Biochem., 14 (3), 405-13 (1966). (441) Cressman, R.-4., Diss.Abstr., B, 28 (4), 1597-8 (1967). Univ. Microfilms (Ann Arbor, M i c h . ) , O r d e r N o . 67-13,048, 183 pp. (442) Cunha, 0. R. P. da, Cunha, A. P. da, Bol. Escola Farm., Univ. Coimbra, Ed. Cient., 25, 54-67 (1965); Chem. Abstr., 65,, 3671a (1966). (443) Curry, A. S., Symposium, “Identification of Drugs and Poisons,” London, March 1965. Pharmaceutiral Societv of Great Britain, pp 39-46; Anal. At&., 13, 3360 (1966). (444) Curtius, H. Ch., Mueller, AI., J . Chromatogr., 32 (2), 222-9 (1968). (445) Curtze, A., Holland, R., Deut. Apotheker-Ztg., 107 (5), 147-9 (1967); Chem, Abstr., 66, 1 0 8 2 8 3 ~(1967). (446) Czlonkowska, G., Bitna-Szlachta, A,, Gradecka, J., Aptechn. Delo, 15 (6), 77-9 (1966); Chem. Abstr., 66, 79628e (1967). (447) Czyszewska, S., Kaczmarek, F., Lutomski, J., Speichert, H., Herba Pol., 12 (2’). 87-94 11966): , , Chem. Abstr.. 66. 79611; 11967).

(466) Del Grande, P., Monai, A,, Boll. Chim. Farm., 106 (8), 541-52; Chem. Abstr., 68, 6209a (1968). (467) Delonca, H., Dolique, R., Bardet, L., Ann. Pharm. FT., 25 (3), 225-35 (1967); Chem. Abstr., 67, 47088h (1967). (468) Demain, A. L., Nature, 210 (5034), 426-7 (1966). (469) D e Marco, A., Mecarelli, E., Farmaw, Ed. Prat., 22 (la), 795-9 (1967); Chem. Abstr., 68, 4320273 (1968). (470) Denisov. hl. D.. Farm. Zh. (Kiev). 2 2 (4), 74-9 (1967j; Chem. Absir., -68; 33158q (1968). (471) Dennen, D. W., J . Pharm. Sci., 56 (lo), 1273-6 (1967). (472) De Santis, A., Re Garbagnati, V., Boll. Chim. Farm.. 106 (1). 51-3 (1967): ,. Chem. Abstr., 67,’111507y (19673. (473) Ibid. (3), pp 193-7; Chem. Abstr., 67. 1115OOr (1967). (474j Ti& i., (7), pp 497-9; Chem. Abstr., 68, 33219k (1968). (475) Defosse:;, B., Bull. SOC.Chim. Fr., 1965 (6). 1889-90: Anal. Abstr.. 13.6435 (1966). ’ ’ (476) Deshpande, G. R., Narasimhachuri, N., Hindustan Antibiot. Bull., 9 (3), 163 (1967); Chem. Abstr., 67, 471141, (1967). (477) Detter, F., Dietrich, J., Klingmuller, V., Klin. Wochenschr., 44 (2), 100 (1966); Anal. Abstr., 14, 2759 (1967). (478) Deutsch, M. J., Weeks, C. E., J . Ass. O$c. Agr. Chem., 48 (6), 1248 (1965). (479) Devani, M. B., Shishoo, C. J., Indian J . Pharm., 29 (4), 125-7 (1967); Chem. Abstr., 67, 676225 (1967). (480) Zbid. (6), pp 177-9; Chem. Abstr., 67, 1114992: (1967). (481) Ibid. ( l l ) , pp 307-9; Chem. Abstr., 68, 16192d (1968). (482) Devani, 51.B., Shishoo, C. J., Patel, N. hf., ibid. (3), pp 98-100; Chem. Abstr., 67, 14900p (1967). (483) Devyatnin, V. A., Petrenko, G. G., Khim.-Farm. Zh. 1 (6), 39-40 (1967); Chem. Abstr., 67, 94045b (1967). (484) Devyatnin, V. A., Svetlaeva, V. M., Shnaidman, L. O., Baigel’man, L. M., ibid. (5), pp 39-41; Chem. Abstr., 67, 67654t (1967). (485) Dezelic, M., Grujic-Vasic, J., Popovic, R., Tehnika (Belgrade), 19, 2087a-90a (1964); Chem. Abstr., 65, l5163e (1966). (486) Dezelic, M.,Trkovnik, M., Popovic, R., Dimitrijevic, D., Acta Pharm. Jugoslav., 17 (2), 81-6 (1967); Chem. Abstr., 67, 94042y (1967). 319?9i (1967). (487) Diab, I. M., Gomoll, A. W., Steroids, (455) Das Gupta, V., Cadwallader, D. E., 8 (2), 109 (1966). J . Pharm. Sci., 57 (l),112-17 (1968). (488) Dickes, G. J., J . Ass. Public Analysts, (456) Datta, D. D., Ghosh, D., Indian J . 4 (3), 45 (1966). Pharm., 28 (5), 133-4 (1966); Chem. (489) Dicks-Bushell, M. W.,J . C h ~ o Abstr., 65, l5157b (1966). matogr., 27 (l),96-103 (1967). (457) Ibid.. 29 (6). 179 (1967): , . Chem. (490) Dijkhuis, I. C., Pharm. Weekblad, Abstr., 67, 111514~(1967). 102 (36), 907-22 (1967); Chem. Abstr., (458) Davidson, A. E., J . Ass. Oflc. Anal. 67, 1114663’ (1967). Chem., 50 (3), 669-73 (1967). (491) Dimkovic. R.. Arhiv Farm. (Bel(459) Davies, A. hl. C., J . Ass. Public ‘ grade), 15 (6), 463-71 (1965); Chem. Analysts, 4 (I), 11 (1966). Abstr., 66, 22221n (1967). (460) Davis, S., Arnold, A,, J. Ass. O ~ C . (492) Dimofte, L., Simionovici, R., SterAgr. Chem., 48 (6), 1134 (1965). Stefan, ., V.,Pharmazie, 21 (6), escu, >I (461) Deavin, J. C., Drey, R. E. A,, 349-50 (1966); Chem. Abstr., 65, 10426e Foster, G. E., J . Pharm. Pharmacol., (1966). Suppl., 19, 105-9 (1967). (493) Dinic, M., Arhiv Farm. (Belgrade), (462) De Becker, J., Hupin, C., Massart, 15 (3), 189-90 (1965); Chem. Abstr., 66, N., J . Pharm. Belg., 22 (5-6) 188-98 31987u (1967). (1967): Chem. Abstr.. 67. 94050~(19671. (494) Ibid., (4), pp 311-14; Chem. Abstr., (463) Debates, J. H., Casile, J. L., Intern. 66 2222213 (1967). Sugar J.,68, 173 (1966). (495) D i Pasquale, S., Corigliano, F., Ann. (464) Delarge, J., Thunus, L., Libert, N., Fac. Econ. Com., Univ. Studi Messina, 4 J . Pharm. Belg., 21 (749,375-86 (1966); (l), 59-64 (1966); Chem. Abstr., 68, Chem. Abstr., 66, 22293n (1967). 432259 (1968). (465) Delarue, J. C., Bull. SOC.Chim. (496) Dittmann, J., Deut. Gesundheitsw., Biol., 48 (2), 364-5 (1966); Anal. Abstr., 22 (26), 1217-18 (1967); Chem. Abstr., 14, 5622 (1967). 68, 627383’ (1968). ~

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(497) Dittmann, J., Liem, G., 2. Klin. Chem., 4 ( 5 ) , 266 (1966); Anal. Abstr., 14, 5604 (1967). (498) Divekar, P. V., Vora, V. C., Khan, A. W., J . Antibiot. (Tokyo), Ser. A , 19 (2), 63-4 (1966); Chem. Abstr., 65, 5699 (1966). (499) Dmitrovskii, A. A., Eremina, G. V., Biokhimiya, 32 (6), 1209-9 (1967);Chem. Abstr., 68, 53296m (1968). (500) Doan, L. A., Chatten, L. G., J. Pharm. Sci., 54, 1605 (1965). (501) Dobronravova, E. K., Markman, A. L., Khim. Prir. Soedin., 2 ( 5 ) , 333 (1966); Chem. Abstr., 66, 79615y (1967). (502) Dokladalova, J., Stankova, O., Mikrochim. Ichnoanal. Acta, 1965, (4), DD 725-8: Anal. Abstr.. 13. 4188 (1966). ( 5 b j ) Donato, S. J., J.’Phhrm. S‘ci., 54 (6). 917-18 - - fl965). --, (504) Doornbos, D. A,, Pharm. Weekblad, 102 (6), 93-103 (1967); Chem. Abstr., 66, 689641r (1 4671,. ,-”-. (505) jrbid. (43). DD 1095-1108; Chem. Abstr.. 67. 120224i’ (1967). iL506)Doorenbos. H. J.. Rekker. R. F.. Na&, W. Th:, ibid.,‘101 (24); 525-30 (1966); Chem. Abstr., 65, 8677d (1966). (507) Ibzd. (26), PP 565-9; Chem. Abstr., 65, 8671h (1966): (508) Doorenbos. H. J.. van der Pol. H. J.,’Rekker, R. ‘F., Nauta, UT.Th., ;bid., 100 (28), 841 (1965); Anal. Abstr., 13, 6500 (1966). (509) Doorenbos, H. J., van der. Pol, H. J., Simoons, J. R. A., Rekker, R. F., Nauta, W. T., ibid. (26), p 789; Anal. Abstr., 13, 5817 (1966). (510) Doorenbos, N. J., Sharma, R. K., J . Chromatogr., 29 (2), 393-5 (1967). (511) Dorozhinskii, V. B., Brazhnikova, M.G., Lomakina. N. N., Antibiotiki, 11 (lo), 898-901 (1966); Chem. Abstr., 66, 222602 (1967). (512) Doskotch, R. W.,Malik, hl. Y., Beal, J. L., J. Org. Chem., 32 (lo), 3253-4 (1967). (513) Douglas, J. S., Nicholls, P. J., J . Pharm. Pharmacol., Suppl., 17, 115s17s (1965). (514) Doyle, R. J., Burgan, H. M., Anal. Biochem., 17 ( l ) ,171-4 (1966). (515) Doyle, T. D., J . Ass. Ofic. Anal. Chem., 50 (3), 655-7 (1967). (516) Doyle, T. D., Levine, J., ANAL. CHEM.,39 ( l l ) , 1282-7.(1967). (517) Doyle, T. D., Levine, J., J . Ass. Ofic. Anal. Chem., 51.(1), 191-9 (1968). (518) Dryanovska-Noninska, L., Gagauzov, I., Botev, B., Farmatsiya (Sofia), 16 (6), 36-9 (1966); Chem. Abstr., 66, 9 8 5 6 1 ~(1967). (519) Drygieniec, D., Balkowska, J., Farm. Pokka, 22 (lo), 753-5 (1966); Chem. Abstr., 67, 57288n (1967). (520) Drygienic, D., Mlynarczyk, Z., ibid. (6), pp 437-8; Chem. Abstr., 66, 4 9 2 6 9 ~(1967). (521) Dryon, L., J . Pharm. Be@, 21 (9lo), 433-76 (1966); Chem. Abstr., 66, 588659 (1967). (522) DSouza, A. A., Shenoy, K. G., Indian J. Pharm., 29 (12), 327-9 (1967) ; Chem. Abstr., 68, 332379 (1968). (523) Dumanovic, D., Vollre, J., Vajgand, V., J . Pharm. Pharmacol., 18 (8), 50712 (1966). (524) Duncker, C., Kirk-Othmer Encycl. Chem. Technol., 2nd Ed., 3, 420-39 (1964); Chem. Abstr., 65, 646f (1966). (525) Dusinsky, G., Antolik, P., Cesk. Farm., 15 (3), 139-41 (1966); Chem. Abstr., 65, 36691 (1966). (526) Ibid., 16 (3), 120-2 (1967); Chem. Abstr., 67, 676367, (1967). (527) Ibid. (9), pp 461-3; Chem. Abstr., 68, 7 2 2 8 5 ~(1968). (528) Dusinsky, G., Faith, L., Pharmazie, 22 (9), 475-82 (1967); Chem. Abstr., 68, 53280b (1968). \ - I ,

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(529) Dutillio, N. W., Jacobs, C. S., Holmes, W. L., J . Chromatogr., 20, 354 (1965). (530) Dutrieux, F., J . Pharm. Belg., 22 (1-2)! 31-40 (1967); Chem. Abstr., 67, 5726~(1967). (531) Dutrieux, F., Nonclero, &I., Kys, C Laboureur, Mrs., ibid. (5-6), pp 22b-36; Chem. Abstr., 67,84929d (1967). (532) Dutt, Rl. C., J . Ass. Ofic. Anal. Chem., 49 (4), 8 5 h 6 (1966). 1533) Dzvuba. N. P.. Izmailov. N. A.. Ukr. ghim.‘Zh., 31’ (4), 403-8 (1965); Anal. Abstr., 13, 4011 (1966). (534) Ebata, M.,Takahashi, Y., Otsuka, H., J . Chromatogr., 25 (l),1-10 (1966). (535) Ebel, S.,Arch. Pharm. (Weinhelm), 300 (5), 472-4 (1967); Chem. Abstr., 67, 111504~(1967). (536) Eberhardt, H., Debackere, M., Arzneim.-Forsch., 15 (8), 929 (1965) ; Anal. Abstr., 13, 7095 (1966). (537) Eckschlager, K., Fidelrova, J., Cesk. Farm., 13, 371-3 (1964); Chem. Abstr., 65, 19931h (1966). (538) Edmundson, I. C., in (‘Advances in Pharmaceutical Sciences,” H. S. Bean, A. H, Beckett, J. E. Carless, Eds., Vol. 2, Academic Press, New York, N.Y. (539) Edwards, R. W. H., Trafford, D. J. H., J . Chromatogr., 21, 275 J1966). (540) Eechaute, W.,Clin. Chzm. Acta, 13 (6), 785 (1966); Anal. Abstr., 14, 6349 (1967). ~_ -.,.

(541) Eechaute, W., Steroids, 8,633 (1966). (542) Efimenko, A. M., Farm. Zh. (Kiev), 21 (2), 32-4 (1966); Chem. Abstr., 65, 2065a (1966). (543) Egli, K. L., Romano, A., J . Ass. Offic. Anal. Chem.. 51 (1).11-14 (1968). 154;) Egorov, Ts. A., Reshetov, P. D., Khokhlov, A. S., J. Chromatogr., 19,214 (1965). (545) Eide, G. J., Speiser, P., Acta Pharm. Suecica, 4 (3), 185-200 (1967); Chem. Abstr., 67, 76251m (1967). (546) Ibid., pp 201-10; Chem. Abstr., 67, 76252n (1967). (547) Eiden, F., Kochs, I., Planta Med., 15 (I), 81-8 (1967); Chem. Abstr., 66, 118889n (1967). (548).Eilhauer, H. D., Fahrig, P., KrautSchick, G., Fresenius’ 2. Anal. Chem., 228 (4), 276-80 (1967): Chem. Abstr., 67, 60742m (19671. (549) Eisdorfer,’I. B., Post, A., J . Pharm. Sei., 56 (9), 1092-7 (1967). (550) Eisdorfer, I. B., Warren, R. J . , Thompson, W. E., Zarembo, J. E., ibad., 55 (7);. 734-5 (1966). (551) Ejima, A,, Tokusawa, J., Ishibashi, Rl., Yakugaku Zasshi, 87 (7), 769-77 (1967): , , Chem. - - Abstr.. 67. 84926a (1967). (552j -Eklund, E;,-Wesiermarck, H., Farm. Aikakauslehti, 76 (7-8), 164-6 (1967); Chem. Abstr., 68, 33220d (1968). (553) Elbanowska; A., Kaczmarek, F., Herba Pol., 12 (3), 173-7 (1966); Chem. Abstr., 67, 8489% (1967). (554) Elefant, M., Chafetz, L., Talmage, J. M.,J . Pharm. Sci., 56 (9), 1181-3 (1967). (555) Elefant, hf., Talmage, J. M., ibid. (1) p 133-4. (556)’ Efizarova, G. L., Matvienko, L. G., Izv. Sibirsk. Otd. Akad. Nauk SSSR, Ser. Khim. Nauk, 1966 (3), 118-21; Chem. Abstr., 67, 17648y (1967). (557) El-Keiy, M. A., Ahmed, Z. F. AbdelKader, E. M., Abel-Wahab, S. XI., J . Pharm. Sci. U. Arab Rep., 5, 139-54 (1964); Chem. Abstr., 66, 22255b (1967). (558) El-Keiy, M. A., Ahmed, 2. F., AbdelRahab, S. Rf., ibid., pp 155-66; Chem. Abstr., 66,22254a (1967). (559) Ellert, H., Ceglarski, R., Regosz, A., Farm. Polska, 22 (3), 185-8 (1966); C. A. 67,5733j (1967). (560) Ellert, H., Sell, E., ibib., 21 (5-61, 167 (1965);Anal. Abstr., 13,5804 (1966).

(561) Ibid. (19-20), pp 739-42; Chem. Abstr., 65, 2068d (1966). (562) Ibid., 22 (lo), 745-7 (1966); Chem. Abstr., 67, 471181 (1967). (563) Ibid.. 23 (5-6). 453-5 (1967): Chem. Abstr., 67, 120223e (1967): (564) Ellis. G . P.. Chem. Ind.. 1966. 1221. pp 902-3; Anal: Abstr., 14, 6184 (i967): (565) Elliston, S. C., Hammond, M. D., Analyst, 90 (1070), 298-300 (1965). (566) Elste, U., Winkhaus, U., Duda, H., Deut.Apotheker-Zto.. 106. 568-72 11966): Chem. Abstr., 67, 84924y (1967). (567) Emrich, D., Reichenbach, H., Hoffmann, G., Keiderling, R., Nuc1.-Med., 6 (2), 149-58 (1967); Chem. Abstr., 67, 84945f (1967). (568) Enache, S., Constantinescu, T., Gamenti, V.,Farmacia (Bucharest), 16 ( l ) , 51-4 (1968); Chem. Abstr., 68, 7228121. (1968). (569) Enache, S., Constantinescu, T., Ignat, V., ibid., 15 (12), 723-32 (1967); Chem. Abstr., 68, 532859 (1968). (570) Eppert, G., Ihrke, &I., Pharmazie, 22 (2), 88-90 11967); Chem. Abstr., 67, 5722e (1967). (571) Ericson, C., Schill, G., Acta Pharm. Suecica, 3 (6), 405-18 (1966); Chem. Abstr., 67, 14896s (1967). (572) Ermer, E., Pharm. Ztg., 112 (36), 1294-8 (1967); Chem. Abstr., 68,24580~ (1968). (573) Esche, J., Deut. Apotheker-Ztg., 105 (17), 543 (1965); Anal. Abstr., 13, 4414 (1966). (574) Fabrizio, F. de, J . S.African Chem. Inst., 20 (2), 194-6 (1967); Chem. Abstr., 68, 53309t (1968). (575) Fairbairn, J. W.,El-RIasry, S., J. Pharm. Pharmacol., Suppl., 19, 93-6 (1967). (576) Fairbrother, J. E., M B Lab. Bull., 7 (3), 45-8 (1966); Chem. Abstr., 66, 61413w (1967). (577) Faith, L., Farm. Obzor, 34, 295-301 (1965); Chem. Abstr., 67, 763492 (1967). (578) Falcao, R. F., Cavaco, A. C. C., Rev. Port. Farm., 16 (4), 404-6 (1966); Chem. Abstr., 66, 985572 (1967). (579) Falk, H. B., Kelly, R. G., Clin. Chem., 11, 1045 (1965). (580) Fan, hl. C., Wald, W. G., J . Ass. Ofic. Agr. Chem. 48 (6), 1148 (1965). (581) Fare, G., Sammons, D. C. H., Experientia, 22 (lo), 668 (1966); Chem. Abstr., 65, 177405 (1966). (582) Farkas, E., Pharmazie, 21 ( l o ) , 6001 (1966);Chem.Abstr., 66,68994~(1967). (583) Farkas, J. M.!Acta Pharm. Hung., 37 (l), 17-19 (1967); Chem. Abstr., 66, 118890j (1967). (584) Farkas, J. M., Heil, B., ibid. ( 5 ) , pp 215-19; Chem. Abstr., 67, 111489~ (1967). (585) Farkas, S., Zabrak, D., ibid. (4), pp 173-7; Chem. Abstr., 67, 102852e (1967). (586) Farnsworth, N. R., Hilinski, I. hl., J . Chromatogr., 18 (I), 184-8 (1965). (587) Fastlich, E., Searle, B., Davidow, B., Clin. Chem. 11 (3), 436 (1965). (588) Fauli, C., del Pozo, A., Galencia Acta, 18 (1-2), 11-23 (1965); Anal. Abstr., 13, 7099 (1966) (589) Fauli, C., Salazar, R., del Pozo, A., ibid., p 25; Anal. Abstr., 13,7056 (1966). (590) Faure, P., Blanquet, P., Bull. SOC. Pharm. Bordeaux, 102 (4), 239-48 (1963); Chem. Abstr., 65, 3 6 6 9 ~(1966). (591) Favino, A., Diagn. Lab. e Clin., 20 (3), 117-24 (1966); Anal. Abstr., 15, 342 (1968). (592) Fayez, M. B. E., Radwan, A. S., Fresenius’ 2. Anal. Chem., 227 (2), 30-4 11967): Chem. Abstr.. 67. 77832 (1967). (593) Fearnley, D., Roberts, C. P., J . Hosp. Pharm., 23 ( 5 ) , 248-50 (1966). (594) Fearnlev. D.. Tavlor. C. >I., ibid.

(595) Federal Register, 32, 11,522-3 (Aug. 10, 1967). (596) Ibid., 11,523-6. (597) Fedoronko, M.,Koenigstein, J., Linek, K., J . Electroanal. Chem., 14 (3), 357-67 (1967). (598) Feher, T., Clin. Chim. Acta, 14 ( l ) , 83 (1966); A n d . Abstr., 14, 6350 (1967). (599) Feigl, F., Yariv, S., Israel J . Chem., 2 ( 5 ) , 177 (1964); Anal. Abstr., 13, 4213 fl966). I-_.-

(600) Fell, K. R., Ramsden, D., Lloydia, 30 (2), 123-40 (1967); Chem. Abstr., 67, 76218f (1967). (601) Ferre, G., Palomo, A., Palomo, A. L., Vilarrodona, A., Afinidad, 24 (247), 19 (1967); Chem. Abstr., 67, 47116r (1967). (602) Fersht, A. R., Kirby, A. J., J . Amer. Chem. SOC.,89 (19), 4853-7 (1967). (603) Ibid., pp 4857-63. (604) Ficicchia, F., Corriere Farm., 21 (13), 331 (1966); Chem. Abstr.,’ 66, 79649n (1967).

1697-1702 (1966). (607) Filippov, M. P., Terent’eva, I. V., Shkolenko. G. A.. Khim.-Farm. Zh.. 1 (4), 47-9‘ (1967j; Chem. Abstr., 67, 7 6 3 3 2 ~(1967). (608) Finholt, P., Kristiansen, H., Krowczynski, L., Higuchi, T., J . Pharm. Sci., 55 (12), 1435-8 (1966). (609) Finley, K. T., Baitsholts, -4.D., Wilson. J.. Jr.. BishoD. C. A.. Anal. Chim. Act;, 3 7 (2), 257 (1967)‘; Anal. Abstr., 15, 2692 (1968). (610) Fischer, G., Gyogyszereszet, 11 (4), 146-8 (1967); Chem. Abstr., 67, 76249s (1967). (611) Fischer, L. J., Riegelman, S., J . Chromatogr., 21 (21, 268 (1966). (612) Fischer, R., Weixlbaumer, H . , Pharm. Zentralh. Deut., 104 (5), 298-301 (1965); Chem. Abstr., 63, 5451h (1965). (613) Fishbein, L., Fawkes, J., J . Chromatogr., 22 (2), 323-9 (1966). (614) Fleming. R. M.. Clark. W. G.. Fenster, ET’D., T o i n e , J. C., ANAL: CHEM.37, 692 (1965). 1615) Fleurv. S.. Chim. Anal. (Paris). 48 ‘ (6j, 321-35 (1966); Chem. Abstr.,”65, 16791d (1966). 1616) Floret. G.. hlassa. 11. V.. Ann. Pharm. Pi., 24’(3), 2011-8 (1966); Chem. Abstr., 65, 10646c (1966). (617) Fodor. G.. Recent Develov. Chem. Natur. Carbon Compounds, i, 15-160 (1965); Chem. Abstr., 65, 2313b (1966). (618) Fontan, C. R., Diss. Abstr., 26 (12), 6998 (1966); Chem. Abstr., 65, 1 2 0 6 2 ~ (1966); Univ. Microfilms (Ann Arbor, Mich.), Order No. 66-3526, 103 pp. (619) Fontanelli, L., Silvestri, S., Farmaco, Ed. Prat., 23 (3), 139-43 (1968); Chem. Abstr., 68, 89888v (1968). (620) Fooks, J. R., McGilveray, I. J., Strickland, R. D., J . Pharm. Sci., 57 (2), 314-17 (1968). (621) Forberg, IT.,Thrum, H., Antibiot., Advan. Res., Prod. Clin. Use, Proc. Congr., Prague, 1964, pp 499-500 (1965) ; Chem. Abstr., 66, 49272s (1967). (622) Forist, A. -4.,ANAL. CHEM., 36, 1338 (1964). (623) Formanek, I., Fulop, L., Vereph, I., Rev. &led. (Targu-Mures), 12 (3), 300-2 (1966); Chem. Abstr., 66, 68983r (1967’1. (624) laid., pp 302-3; Chem. Abstr., 66, 6 8 9 8 6 ~(1967). (625) Forrest, I. S., Forrest, F. ll., Kanter, S. L., Clin. Chem., 12 (6), 379 (1966). (626) Fossel, E. T., J . Gas Chromatogr., 3 ( 5 ) , 179 (1965).

(627) Fournel, J., Ann. Pharm. Fr., 24 (2), 133 (1966); Anal. Abstr., 14, 3389 (1967). (628) Franca, F. P. de, Dias, G. deO., Rev. Brasil. Farm., 47 ( 2 ) , 67-71 (1966); Chem. Abstr., 65, 15157c (1966). (629) France, J. T., Knox, B. S., J . Gas Chromatogr., 4 ( 5 ) , 173-5 (1966). (630) France, J. T., Rivera, R., McNiven, N. L., Dorfman, R. I., Steroids, 5, 687 (1965). (631) Franchi, G., Pacini, C., Boll. Chim. Farm., 105 ( l l ) , 812-15 (1966); Chem. Abstr., 66, 68958m (1967). (632) Frandsen, P., Dansk Tidsskr. Farm., 40 (2), 19-31 (1966); Chem. Abstr., 65, 2070e (1966). (633) Frank, P., Koechel, F., Krankenhaus-Apotheker, 15 (2), 1-4 (1965); Chem. Abstr., 67, 5664n (1967). (634) Freed, AI., “Methods of Vitamin Assay,” 3rd ed, Interscience, New York, N.Y., 1966, 424 pp. (635) Frei, R. IT.,Frodyma, 11. ?VI.,Chem. Rundschau (Solothurn),19 (2), 26 (1966); Anal. Abstr., 14, 3432 (1967). (636) Freimuth, U., Buechner, M.,Zawta, B., Hubl, W., Keibel, D., Deut. Gesundheitsto., 21 (43), 2039-41 (1966); Chem. Abstr.. 66. 689812, 11967’1. (637) Fienckl, I., Phnta Med., 14 ( 2 ) ,2048 (1966); Chem. Abstr., 65, 569e (1966). (638) French, IT. N., Levi, L., Can. Med. Assoc. J., 94 ( 2 2 ) , 1185-7 (1966). (639) French, W.pi., Riedel, B. A., Can. J . Pharm. Sci., 1 (2), 80-2 (1966). (640) Fresen, J. A., Pharm. Weekblad, 100 (51), 1509-13 (1965); Chem. Abstr., 65, 3669h (1966). (641) Ibid., 102 (28), 659-78 (1967); Chem. Abstr., 67, 111478q (1967). (642) Frigerio, N. A., Chemist-Analyst, 51, 82-3 (1962). (643) Frodyma, hl. XI., Lieu, V. T., ANAL. CHEM.,39 ( i ) ,814-19 (1967). (644) Frolova, V. I., Kuzovkov, -4.D., Rozenfel’d, G. S., Antibiotiki, 11 (4), 298-302 (1966) ; Chem. Abstr., 65.19927~ (1966). (645) Fuerst, W.,Arch. Pharm. (Weinheim) 300 (2), 144-8 (1967); Chem. Abstr., 67, 5676t (1967). (646) Fuertig, W.,Methke, T., Pharm. Prax. (Berlin), 1965 ( l l ) ,pp 248-51; Chem. Abstr., 66, 57309 (1967). (647) Fujisawa, S., Kawabata, S., Yakugaku Zasshi, 86 (6), 504-10 (1966); Chem. Abstr., 65, 105856 (1966). (648) Ibid., pp 510-14; Chem. Abstr., 65, 10585d (1966). (649) Ibid., pp 514-21; Chem. Abstr., 65, 10585f (1966). (650) Furst. A.. Shakuntla. S.. J . Chro’ matogr., 22 (2), 493-5 (1966): (651) Furuya, T., Kojima, H., ibid., 29 (2), 382-7 (1967). (652) Furuya, T., Shibata, S., Iizuka, H., ibid., 21 (l),116-18 (1966). (653) Fusconi, h., Calcagnini, G., Boll. Chim. Farm.. 105. 773-8 11966): Chem. Abstr.. 67. 5735rn‘11967). (654) Ibid.,’pp 778-81; Chem. Abstr., 67, 5737p (1967). (655) Ibid., 106 (l), 54-5 (1967); Chem. Abstr., 67, lll509a (1967). (656 Ibid. (6), pp 410-12; Chem. Abstr., 67, 102851d (1967). (657) Ibid., pp 413-17; Chem. Abstr., 67, 1028192 (1967). (658) Ibid. (7), pp 505-8; Chem. Abstr., 68, 161880 (1968). (659) Fiwa, TI, Kido, T., Tanaka, H., Arch. Pract. Pharm., 25 (2), 138 (1965); Anal. Abstr., 13. 6495 (1966). (660) Gaind, IC. N., Dar,‘R. N.,Popli, S. D., Indian J . Pharm., 27 ( i ) ,199-200 (1965); Anal. Abstr., 13, 6477 (1966). (661) Gaitonde, hl. K., Griffiths, >I., Anal. Biochem., 15, 532 (1966). I

,

(662) Gal, I. E., Pharmazie, 22 (2), 120-3 (1967); Chem. Abstr., 67, 25429t (1967). (663) Galczynska, M., Baranowska, B., Jurkowska, E., Ann. Acad. Med. Lodz., 6, 98-104 (1965); Chem. Abstr., 65, 574d (1966). (664) Gallelli, J. F., Amer. J . Hosp. Pharm., 24 (8), 425-33 (1967). (665) Gallelli, J. F., Drug Intel., 1 (3), 102-5 (1967); Chem. Abstr., 68, 2 4 5 7 5 ~ (1968). (666) Gallelli, J. F., Yokoyama, G., J . Pharm. Sn’., 56 (3), 387-9 (1967). (667) Gallo, G. G., Pasqualucci, C. R., Radaelli, P., Farmaco, Ed. Prat., 18 (a), 78-84 (1963); Chem. Abstr., 66, 1082792 (1967). (668) Gallo, N., Ann. Chim. (Rome), 57 (l), 54-8 (1967); Chem. Abstr., 66, 121889t (1967). (669) Ganatra, J. P., Shastri, M.R., Nehta, R. C., Indian J . Pharm., 30 (3), 67-8 (1968); Chem. Abstr., 68, 899020 (1968). (670) Gandhi, S. B., Patel, P. R., Misarwala, K. H., ibid. (2), pp 45-6; Chern. Abstr., 68, 72282v (1968). (671) Gangemi, G., Boll. Chim. Farm., 106 ( 2 ) , 120-3 (1967); Chem. Abstr., 67, 67676b (1967). (672) Gantes, P., Barat, J., Ann. Pharm. Fr., 25 (6), 447-52 (1967); Chem. Abstr., 67, 102848h (1967). (673) Gantes, P., Juhasz, J. P., ibid., 24 ( l l ) ,687-692 (1966); Anal. Abstr., 15, 1008 (1968). (674) Gapeeva, L. A., Knizhnik, A. Z., Senov, P. L., Aptechn. Delo, 15 (3), 41-3 (1966); Chem. Abstr., 65, 8670h (1966). (675) Garratt, D. C., et al., Analyst (London), 92 (1094), 290-2 (1967). (676) Garrett. E. R.. Advan. Pharm. Sci.. 2. 2-94 11967). ’ (67?) Garrett, E. R., Arzneim.-Forsch., 17 ( i ) ,795-802 (1967); Chem. Abstr., 67, 939232 (1967). (678) Garrett, E. R., Ind. Farm. Bioquim. (Montevideo). 5 (1).3-26 (1964): Chem. Absfr.. 66. 688411 (1967). (679) Garrett, E. R., Blanch, J., ANAL. CHEM.,39 (lo), 1109-13 (1967). (680) Garrett, E. R., Cusimano, A . G., J . Pharm. Sci., 55, 702 (1966). (681) Garrett, E. R., Lambert. H. J.. ibid. (8), p 812. 1682’1 Gaskell. -4.J.. Joule. J. A.. Tetrahedron, 23 (lo), 4053-63 ‘(1967): (683) Gasparec, Z., Acta Pharm. Jugoslav., 17 (2), 103-6 (1967); Chem. Abstr., 67, 94028y (1967). (684) Gaudiano, A., Petti, G., Polizzi, U., Tartarini. S.. Ann. Ist. Suwer. Sanita. 2 ( 5 ) , 537L9 11966); Chem: Abstr., 66, 108226a il967). ~ . . ~ ~ - . (685) Gaudiano, A., Polizzi-Sciarrone, hl., ibid., 1 (9-lo), 588-602 (1965); Chem. Abstr., 65, 8675a (1966). (686) Gautier, J. A., Pellerin, F., Baylocq, G., Ann. Pharm. Fr., 24 (6), 405-10 (1966); Chem. Abstr., 66. 14078f (1967). (687) Gavrila, E., Braun, SI., Sorescu, E., Rev. Chim. (Bucharest), 17 (2), 108 (1966); Anal. Abstr., 14, 3534 (1967). (688) Gaylord, 11. C., DeBoer, J. R., Brady, L. R., J . Pharm. Sci., 56 (9), 1069-74 (1967). (689) Geczy, G., Magy. Kem. Foly., 73 (2), 85-7 (1967); Chem. Abstr., 66, 98538s (1967). (690) Gein, L. G., Sumbaikina, Z. A,, Farmatsiya (hloscow), 16 (3), 41-3 (1967); Chem. Abstr., 67, 84919a (1967). (691) Gelbakhiani, P. G., Dolaberidze, T. AI., Trapaidze, M. K., Geleishvili, P. V., Tr. Tbilis. Med. Inst., 22, 390-3 (1965); Chem. Abstr., 67, 120215d (1967). (692) Geller, L. E., Silberman, N., Steroids, 9 (2), 157-61 (1967). (693) Gel’perin, N. I., Klyueva, L. M., Ainshtein, V. G., Med. Prom. SSSR, 20 \ - - - - ,

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(3), 15-17 (1966); Chem. Abstr., 65, 569h (1966). (694) Gemmill, C. L., Gemmill, D. D., Anal. Biochem., 10 (3), 504-6 (1965). (695) Gemzova, I., Gasparic, J., Collection Czech. Chem. Commun., 31 (6), 2525-33 (1966); Chem, Abstr., 65, 3773a (1966). (696) Genest, K., J . Chromatogr., 19, 531 (1965). (697) Genest, K., Belec, G., Can. J . Pharm. Sci., 2 ( 2 ) , 44-7 (1967). (698) Gengrinovich, A. I., Dozorova, I. I., Uzb. Khim. Zh., 10 (3), 19-21 (1966); Chem. Abstr., 65, 18428b (1966). (699) Gengrinovich, A. I., Kadyrov, Ya. K., Drebentsova, N. F., Tr. Tashkentsk. Farmatsevt. Inst., 4,272-7 (1966) ; Chem. Abstr., 67, 254361 (1967). (700) Gengrinovich, A. I., Mel’kumova, E. V., ibid., pp 263-6; Chem. Abstr., 67, 25435s (1967). (701) Genkina, G. L., Abubakirov, N. K., Khim.-Farm. Zh., 1 (6), 47-9 (1967); Chem. A bstr., 68, 62222 (1968). (702) Gensch, IC. H., Higuchi, T., J . Pharm. Sci., 56 ( 2 ) , 177-84 (1967). (703) Georgievskii, V. P., Med. Prom. SSSR, 20 ( l l ) , 62-4 (1966); Chem. Abstr., 66, 11888ik (1967). (704) Georgievskii, V. P., Kvartnik, V. hl., Farm. Zh. (Kiev), 22 (5), 87-90 (1967); Chem. Abstr., 68, 43208~(1968). (705) Georgievskii, V. P., Tsarenko, S. Ya., Dzyuba, S . P., Farmatsiya (Lloscow), 16 ( l ) ,50-3 (1967); Chem. Abstr., 66, 985145 (1967). (706) Gerdes, H., Staib, K., Klin. Wochenschr., 43 (13), 744 (1965); Anal. Abstr., 13, 6444 11966). (707) Gerlach, H., Pharmazie, 22 ( l l ) , 651-3 (1967); Chem. Abstr., 68, 53303m (1968). (708) Gerlach, H., Pharm. Zentralh. Deut., 105 (8), 526-9 (1966); Chem. Abstr., 65, 16i91b (1966). (709) Zbid. (12), pp 7il-2; Chem. Abstr., 66, 58873r (1967). (710) Gerritsma, K. K., Vijver, L. hl. van der, Pharm. Weekblad, 101 (35), 733-41 (1966): Chem. Abstr., 67, 763472 (1967). (711) G e r t i g , H . , K o w a l e w s k i , Z., Kowaczyk, K., Herba Pol., 12 (2), 1111 i (1966); Chem. Abstr., 66, 79624a (1967). (712) Gheorghiu, A., Ionescu-Matiu, E., Platon, F., Lupulescu, V., Studii Cercetari Biochim., 10 (4), 319-24 (1967); Chem. Abstr., 68, 814310 (1968). (713) Gheorghiu, C., Stoica, hl., Analele Eniv. Bucuresti, Ser. Stiint. Nut., 12 (41), 55-62 (1963); Chem. Abstr., 65, 86775 (1966). (714) Ghosh, D., Datta, D. D., Bose, P. C., J . Chromatogr., 32 (4), 774-6 (1968). (715) Giacopello, D., ibfd., 19, 172 (1965). (716) Giao, W.,Polonia, J., Anais Fac. Farm. Porto, 25 81-95 (1965); Chem. Abstr., 66, 118878h (1967). (717) Gibbs, I. S., Tuckerman, &I.RI., J . Pharm. Sci., 54, 907 (1965). (718) Giebelmann, R., Pharmazie, 21 (3), 171 (1966); Chem. Abstr., 65, 5305s (1966). (719) Giovannini, AI., Gaboardi, F., Minerva Pediat., 18 (20), 1026 (1966); Anal. Abstr., 14, 5617 (1967). (720) Givner, LI. L., Rochefort, J. G., Sferoids, 6 (4),485-9 (1965). (721) Gjaldbaek, J. C., Worm, K., Dansk Titlsskr. Farm., 39 (4), 141 (1965); Anal. Absfr., 13, 4404 (1966). (722) Glombitza, B.IT., Pharm. Zentralh. Deut., 106 ( 7 ) , 441-2 (1967); Chem. Abstr.. 67. 102838e (1967). (723) Gloria, T. S., Rev. Fuc. Farm. Bioqitim. Univ. Suo Paulo, 4 (2), 391-400 (1966); Chem. Abstr., 67, 84917 (1967). (724) Gluzman, hl. Kh., Dashevskaya, B. I., Tridman, G. Sf.)Med. Prom. SSSR, 228

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19 (5), 16-22 (1965); Chem. Abstr., 63, (755) Graf, E., Deut. Apotheker-Ztg., 105 (24), 785 (1965); Anal. Abstr.. 13. 5770 40965 (1965): (725) Goeckeritz, D., Pharmazie, 21 ( l l ) , (1966). 668-74 (1966); Chem. Abstr.. 66. 98510b (756) Graf, E., Vogt, S., Burk, C., itrid., (1967). 107 (2), 38-41 (1967); C. A. 67, 67628n (726) Goenechea, S.,Fresenius’ Z. Anal. (1967). Chem., 225,, 3C-6 (1966); Chem. Abstr., (757) Graf, E., Vogt, S.,Graser, M., Burk, 66,796142 (1967). C., Pharm.Ztg., 111 (40), 1467-70 (1966); (727) Goenechea, S.,2. Anal. Chem., 218 Chem. Abstr., 66, 40739s (1967). (6), 416-26 (1966); Chem. Abstr., 65, (758) Grafnetterova, J., Clin. Chim. Acta, 8718g (1966). 11 (2), 128 (1965); Anal Abstr., 13, 5137 (728) Goerlich, B., Arzneim.-Forsch., 15 11966). ( 5 ) , 493-503 (1965); Chem. Abstr., 65, (759) Graham, J. H., J . Pharm. Sci., 54, 19931a 11966). 1665 (1965). (729) Goldman; M.,Day, R. A., Ohio J . (760) Gramberg, K., Arhiv Farm. (BelSci., 67 (3), 190-1 (1967); Chem. Abstr., grade), 15 (5), 427-9 (1965); Chem. 67, 111481k (1967). Abstr., 66, 58855m (1967). (730) Goldstein, D., Chemist-Analyst, 56 (761) Granath, L. E., Bladh, E., Edlund, (4), 91-2 (1967). J., J . Dent. Res., 46 (2), 417-23 (1967); (731) Golkiewicz. W..Jusiak. L.. SoczewChem. Abstr., 66, 118896n (1967). inski, E., Diss: Pharm. Pharmacol., 18 (762) Graner, R. F., Circ. Farm., 24 (212), (5), 485-9 (1966); Chem. Abstr., 67, 213-24 (1966); Chem. Abstr., 67, 254115 36381s (1967). (1967). (732) Golovkin, V. A., Farmatsiya (Mos(763) Graner, R. F., ibid. (213), pp 293cow), 16 ( 2 ) , 71-4 (1967); Chem. Abstr., 316; Chem. Abstr., 67, 254129 (1967). 67, 25425p (1967). (764) Gras, G., Castel, J., Trav. SOC. (733) Golovkin, V. O., Posdnyakova, V. Pharm. Montpellier, 25 (3), 178-84 T., Farm. Zh. (Kiev), 22 (3), 29-33 (1966); Chem. Abstr., 65, 3672h (1966). (1967); Chem. Abstr., 68, 62122u (1968). (765) Grauwiler, J., Binkert, J., Arzneim.(734) Gomez, E. C., &?Lim. Ind. (Bogota), Forsch., 17 (lo), 1266-70 (1967); Chem. 6 (l), 11-14 (1966); Chem. Abstr., 67, Abslr., 68, 43198s (1968). 11137% (1967). (766) Crecu, I., Barbu, S., Farmacia (Bu(735) GGnzalez, 0. hf. A , , hleier, G. K., charest), 15 ( l ) , 1-6 (1967); Chem. Rev. Real. Acad. Cienc. Exact. Fis. Nut. Abstr., 66, 98549w (1967). Madrid, 59 (3), 507-17 (1965); Chem. (767) Crecu, I., Barbu, S.,Rev. Chim. Abstr., 65, 16795f (1966). (Bucharest), 17 (4), 236-7 (1966); Chem. (736) Goodall, R. R., Goldman, J., Woods, Abstr., 65. 5305d (1966). J., Pharm. J., 200 (5437), 33-4 (1968). (768) Idid.,‘ 18 (8); 498 (1967); Chem. (737) Goodhart, F. W., Lieberman, H. A,, Abstr., 68, 33239s (1968). Mody, D. S., Ninger, F. C., J . Pharm. (769) Grecu, I., Cures, E., Farmacia (BuSci., 56 ( l ) ,63-7 (1967). charest), 13 (9), 527 (1965); Anal. Abstr., (738) Gopal, N. G. S., Indzan. J . Pharm., 14, 372 (1967). 28 (2), 34-6 (1966); Chem. Abstr., 65, 571a (1966). (770) Ibid., 14 (5), 303-6 (1966); Chem. (739) Gopal, N. G. S Iya, V. K., J . Sci. Abstr., 65, 12062a (1966). Ind. Res.. 26 (4). ik3-8 (1967): Chem. (771) Grecu, I., Cures, E., Neamtu, M., Abstr., 67, 67604b (1967). zlnd. (6), pp 361-5; Chem. Abstr., 65, (740) Gopal, N. G. S., Patel, K. M., 134569 (1966). Indian J . Pharm., 28 ( 7 ) , 187-9 (1966); (772) Greff, R. A,, Setzkorn, E. A,, Leslie, Chem. Abstr., 65, 167895 (1966). W. D., J . Amer. Oil Chem. SOC.,42 (3), (741) Gorge, J. L., Monteoliva, M., Mayor, 180 (1965). F., An. Real SOC.Espan. Fis. Quim., Ser. (773) Gressel, P. D., Gallelli, J. F., J. B., 63 (4), 465-78 (1967); Chem. Abstr., Pharm. Sci., 57 (2). 335-8 (1968). 67. 84922w 119671. (774) Gries, G., Pfeffer, IC. H., Zappi, E. (742)’ Gorog, S., Acta Chim. Acad. Sci. J., Klin. Wochenschr.,43 (9), 515 (1965); Hung., 51, (2), 221 (1967);Anal. Abstr., Anal. Abstr., 13. 5070 (1966). . . 15, 2922 (1968). (775) Griffiths; B.‘W., J. Pharm. Sci., 55, (743) Gorog, S., Magy. Kem. Foly., 72 353 (1966); Anal. Abstr., 14,4242 (1967). i l l ) . 497 11966): , , . Anal. Abstr.. 15. 1009 (776) Grims, XI., Kupinic, hf.; Acta Pharm. (1968). Jugoslav., 17 (l),19-28 (1967); Chem. (744) Gorog, S.,Foldes, V., Acta Chim. Abstr., 67, 57286k (1967). Acad. Sn’. Hung., 48 (3), 249-54 (1966); (777) Grims; M., Senjkovic, R., ibid., pp Chem. Abstr., 65, 10425h (1966). 3-17; Chem. Abstr., 67, 57279k (1967). (745) Gorog, S.,Tomcsanyi, L.,ibid.,47 ( 2 ) , 121 (1966);Anal. Abstr., 14,3473 (1967). (778) Grochulski, A., Acta Polon. Pharm., (746) Gorog,S.,Tomcsanyi,L.,Magy.Kem. 24 (5), 555-6 (1967); Chem. Abstr., 68, Foly., 71 ( 5 ) , 220 (1965); Anal. Abstr., 43199t (1968). 13, 5096 (1966). (779) Groebel, W., Arch. Pharm. (Wein(747) Gottfried, H., Steroids, 5 (3), 385-97 heim), 300 (3), 226-8 (1967); Chem. Abstr., 66, 108295b (1967). ( 19661. (748) Grabarczyk, H., Gertig, H., Chem. (780) Groger, D., Johne, S.,Pharmazie, 20 Anal. (Warsaw), 12 (3), 505-11 (1967); (7), 456 (1965); Anal. Abstr., 13, 6474 Chem. Abstr.. 68. 24567v (1968). (1966). (749) Grabowicz, iV.,Acta Polon: Pharm., (781) Groth, A. B., Wallerberg, G., Acta 24 (3), 315-20 (1967); Chem. Abstr., 68, Chem. Scand., 20 (9), 2628-9 (1966); 627521’ (1968). Chem. Abstr., 66. 58862m (1967). (7.50) Chem. Anal. (War(782) Gruber, ’M.’ P., Klein, R.’W., J. - - Grabowicz. W.. saw), 12 (2),’ 385-91 (1967); Chem. Pharm. Sn‘., 56 (ll),1505-8 (1967). Abstr., 67, 76353w (1967). (783) Gruetzmacher, H. F., Deut. Apo(751) Ibiid. (4),pp 741-4; Chem. Abstr., 68, theker-Ztg., 106 (12), 377-82 (1966); 33252r (19681. Chem. Abstr., 65, 3668g (1966). (784) Grujic-Vasic, J., Ramic, S., Trkov(752) Ibid., pp 745-9; Chem. Abstr., 68, 33253s (1968). nik, hl., Glasnik Drustva Hemicara Technol. N R Bosne Hereegovine, 13-14, 105(753) Grabowicz, W., Kania, K., ibid. (3), 11 (1965); Chem. Abstr., 65, 13455a pp 555-8; Chem. Abstr., 68, 16189h (1966). (1968). (785) Grundmann, W., Gerlach, H., Pharm. (754) Graefe, G., D-Glucose Verw. VerZentralh. Deut., 106 (8), 501-8 (1967); bindugen Med. Biol., 1966, 46-69; Chem. Chem. Abstr., 67, 111483n (1967). Abstr., 68, 16090 (1968). I

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(7861 Gstirner. F.. Korf. G.. Arch. Pharm.. ~299 (9), 7631-8 (1966): Ciem. Abstr., 66; 22283j (1967). (787) Guatelli, M. A., Fernandez, J. C. G., Gamboa, E. F. de, Proc. Can. SOC. Forensic Sci.. 4.249 11965):Anal. Abstr.. 13,6362 ( i 9 6 6 j . (788) Gudzinowicz, B. J., Clark, S. J., J . Gas. Chromatogr., 3 ( 5 ) , 147-51 (1965). (789) Guerello, L. O., Rev. Assoc. Bioquim. Arg., 31 (165-6), 163-8 (1966); Chem. Abstr., 67, 676168 (1967). (790) Guinn, G., J . Chromatogr., 30 (l), 178-82 (1967). (791) Gulimova, T. E., Aptechn. Delo, 15 ( 4 ) ,43-6 (1966); Chem. Abstr., 65,15156g (1965). (792) Gupta, D., McCafferty, E., Steroids, 8 ( 4 ) , 451-9 (1966). (793) Gurevich, A. I., Kiseleva, 0. A., Kolosov, M. N., Kuznetsov, V. D., Onoprienko, V. V., Rozynov, B. V., Antibiotiki, 12 (lo), 880-4 (1967);Chem. Abstr., 68, 24522b (1968). (794) Gusev, S . I., Kozhevnikova, I. A., Mater. Nauchn. Konf., Permsk. Med. Inst., Sb., Perm., 1964, pp 70-1; Chem. Abstr., 65, 573d (1966). (795) Guseva, L. N., Aptechn. Delo, 15 ( 4 ) , 74-8 (1966); Chem. Abstr., 65, 13453e (1966). (796) Ibid. ( 5 ) ,pp 32-9; Chem. Abstr., 66, 14061v (1967). (797) Guseva, L. N., Sb. Nauchn. Tr. Tsentr. Aptechn. Nauchn.-Issled. Inst., 6 , 103-9 ( 1 9 6 4 ) ;Chem. Abstr., 65, 8676j (1966). (798) Guseva, L. N., Vestfal, K.I., Kuleshova, A l . I., Farmatsiya (Moscow), 16 ( 3 ) , 46-51 (1967); Chem. Abstr., 67, 6766% (1967). (799) Gustavii, K., Schill, G., Acta Pharm. Suenca, 3 ( 4 ) , 241-58 (1966); Chem. Abstr., 67, 1 0 2 8 1 5 ~(1967). (800) Gustavson, W.R., Ledin, G., Furst, A., J.Chromatogr., 24 ( l ) ,288-90 (1966). (801) Gutbier, G., Ihn, W.,Mikrochim. Acta, 1966 (1-2), pp 24-33; Anal. Abstr., 14. 4019 (1967). (802j Guth, E. P., l\Ionsour, Z., J . Pharm. Sci., 56 ( 3 ) ,376-9 (1967). (803) Guttman, D. E., J . A s s . Ogic. Anal. Chem., 50 ( 6 ) , 1354-6 (1967). (804) Guttman. D. E.. J . Pharm. Sci.. 55 ( g j , 919-22 (1966). ’ (805) Guven, .(I C., Eczacilik Bulteni, 7 ( 2 ) , 25 (1965); Anal. Abstr., 14, 3520 (1967). (806) Guven, K. C., Aktulga, A., ibid., 9 ( 4 ) , 57-64 (1967); Chem. Abstr., 67, 8478Oy (1967). (807) Guven, K. C., Cobanlar, S., ibid. ( 6 ) ,pp 98-103; Chem. Abstr., 67, 102839f (1967). (808) Guven, K. C., Gecgil, S., Istanbul Univ. Eczacilik Fak. Mecm., 2 (l), 46-55 ( 1 9 6 6 ) ;Chem. Abstr., 65. 19931f (1966). (809) Guven, K. C., Gecgii, S., Pekin, O:, Eczacilik Bulteni, 8 ( 6 ) , 158-62 (1966); Chem. Abstr., 65. 18427d (1966). (810) Guven, K. C’., Hincal, A., ;bid. (11l a ) , pp 202-5; Chem. Abstr., 67, 5734k (1967). (811) Ibid., 9 ( 7 ) , 105-20; ( S ) , 121-35; ( 9 ) , 137-59 (1967); Chem. Abstr., 68, 62644a (1968). (812) Guven, K. C., Hincal, A., Istanbul Univ. Eczacilik Fak. Mecm. 1 ( 2 ) , 153-6 ( 1 9 6 5 ) ; Chem. Abstr., 65, 8668d (1966). (813) Guven, K. C., Ozsari, G., Eczacilik Bulteni, 8 (11-12), 206-9 ( 1 9 6 6 ) ;Chem. Abstr.. 67, 57170 (1967). (814) Idid., 9 ( 2 ) ,is’ (1967);Anal. Abstr., 15, 2902 (1968). (815) Guven, K. C., Ozsari, G., Bayraktar, G., Istanbul Univ. Eczacilik Fak. Mecm., 2 ( 2 ) , 104-7 (1966); Chem. abstr., 67, 148971 (1967). \

(816) Guven, K. C., Pekin, O., Eczacilik Bulteni, 8 (51, 113-23 (1966); Chem. Abstr., 65, 19932b (1966). (817) Ibid., pp 11.5-18; Chem. Abstr., 65, 199339 (1966). (818) Ibid. ( 6 ) , pp 149-57; Chem. Abstr., 65, 19928b (1966). (819) Ibid., pp 163-4; Chem. Abstr., 65, 1 9 9 3 0 ~119661. (820) Ibid. (7-8), pp 176-9; Chem. Abstr., 66, 34637r (1967). (821) Gyenes, I., “Titration in Non-Aqueous Media,” Van Nostrand, Princeton, N.J., 1968, 461 pp. 18221 Hadiiioannou. T. P.. Anal. Chim. Acta, 35”(3),351-9 (1966)’;Chem. Abstr., 65, 13456c (1966). (823) Haensel, R . , L a n g h a m m e r , L., Rimpler, H., Arch. Pharm. (Weinheim), 300 ( 2 ) , 157-68 (1967);Chem. Abstr., 67, 849182 (1967). (824) Haertelt, hl., Boll. Chim. Farm., 106 ( 2 ) , 116-19 (1967); Chem. Abstr., 67, 8 4 9 0 6 ~(1967). (825) Hakl, J., Chem. Listy, 60 ( 2 ) , 259 (1966);Anal. Abstr., 14, 3474 (1967). (826) Hakl, J., J . Electroanal. Chem., 1 1 ( 1 ) . 31-5 11966): Anal. Abstr.. 14. 2764 (1967). (827) Hall. W.A.. Deutsch. 11.J.. J . Ass. ’ Oh. Agr.’ Chem.: 48 ( 6 ) , 1236 (i965): (828) Haller, A., Cesk. Farm., 16 (9), 4967 (1967);Chem,Abstr.,68,81451b (1968). (829) H a l m e k o s k i , J., F a r m . A i k a k auslehti, 75 (9), 274-81 (1966): Chem. Abstr., 66, 222462 11967). 1830) Ibid. ( l o ) ,pp 313-21; Chem. Abstr., ‘ 66, 492792 (1967). (831) Halmekoski, J., Kivinen, .4.,ibid. (7-8), pp 223-39; Chem. Abstr., 66, 57969 (1967). (832) Halmekoski, J., Lukkari, S., ibid., 7 4 ( 5 ) . li3-80 (1965): Chem. Abstr.. 63. 4094h 11965).‘ (833) Halmekoski, J., Vidgren, A., ibid., 75 (9), 282-91 (1966);Chem. Abstr., 66, 22230q (1967). (834) Hamet, R., Foley, K., Shamma, ll., C. R. Acad. Sci., Paris, Ser. D, 265 ( l ) , 71-4 (1967); Chem. Abstr., 67, 117020f (19671. (835) Hamlow, E. E., Peck, G. E., Beyer, L. C., Anesthesiology, 28 ( 5 ) ,934-5 (1967). (836) Hamman, B. L., Martin, 31. XI., Steroids, 10 ( 2 ) , 169-83 (1967). (837) Hammond, K. B., Leach, H., Clin. Chim. Acta, 14 ( 4 ) , 569 (1966); Anal. Abstr.. 15. 963 11968). (838) Hampel, B., Kraemer, J. Sl., Tetrahedron, 25 ( 5 ) , 1601-13 (1966). (839) Hankonyi, V., Karas-Gasparec, V., Acta Pharm. Jugoslav., 17 ( l ) , 41-7 (1967);Anal. Abstr., 15,2063 (1968). (840) Hansel, R., Klaproth, L., A r c h . Pharm., 299 ( l ) ,7 1 (1966);Anal. Abstr., 14, 2814 (1967). (841) Hansen, L. G., Warwick, W.J., A m . J . Clin. Path., 46 ( l ) ,133 (1966). (842) Hara, S., Xlibe, K., Chem. Pharm. Bull. (Tokyo), 15 ( 7 ) , 1036-40 (1967); Chem. Abstr., 68, 33227m (1968). (843) Hara, S., Watabe, T., Ike, Y.,ibid., 14 ( l l ) , 1311-14 ( 1 9 6 6 ) ; Anal. Abstr., 15, 968 (1968). (844) Harada, K., Emoto, S., ibid., pp 1300-2; Chem. Abstr., 6 6 , 4 9 2 8 2 ~(1967). (845) Harb, N., J . Hosp. Pharm., 23 ( 5 ) , 253-5 (1966). (846) Harding, Tu‘., J . Chromatogr., 24 ( 2 ) , 482-4 11966). (847) Hartmann, E., Roepke, H., Fresenius’ 2. Anal. Chem., 232 ( 4 ) , 268-74 (1967);Chem. Abstr., 68, 16166y (1968). (848) Harzdorf, C., Steinhauser, O., Zh. Anal. K h i m . , 210 ( 2 ) , 106 (1965);Anal. Abstr., 13, 4813 (1966). (849) Hasegawa, A., Tanaka, A., Kido, I-., Urakubo, G., Radioisotopes (Tokyo), 16 (111, 598-602 (1967): Chem. Abstr.. 68, 62760k (1968). ~

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(850) Hasegawa, K., Seno, S., Yakugaku Zasshi, 86 (9), 744-8 (1966); Chem. Abstr., 65, 19933a (1966). (851) Hasegawa, K., Seno, S., Moriuchi, %I., Bunseki Kagaku, 15 ( 2 ) , 179-80 (1966); Chem. Abstr., 65, 8676h (1966). (852) Hashmi, M. H.,,Chughtai, F. R., Adil, A. S., Qureshi, T., Mikrochim. Acta, 1967 ( 6 ) ,pp 1111-18; Chem. Abstr., 68, 6225c (1968). (853) Hashmi, hl. H., Rashid, A., Azam, F., ibid., 1966 ( 3 ) , pp 513-17; Anal. Abstr., 14, 5585 (1967). (854) Haug, A., Tidsskr. Kjemi, Bergvasen Met., 26 ( l o ) , 173-8 (1966); Chem. Abstr., 66, 46530p (1967). (855) Hauptmann, S., Winter, J., J . Chromatogr., 21, 338 (1966). (856) Haury, H., Naumann, E., Arzneim.Forsch.. 16 18).1090 (1966): A n a l . Abstr., 14, 7628 (1967). (857) Havlova, M., Nobilis, M., Cesk. Farm., 15 (9), 504-5 (1966); Chem. Abstr., 66, 68894n (1967). (858) Havranek, E., Iludec, P., Svitel, J., Schiller, P., ibid. ( l o ) , p 531; Anal. Abstr., 15, 1044 (1968). (859) Hay, R. R.,Porter, L. J., Morris, P. J., Aust. J. Chem., 19 ( 7 ) , 1197-205 (1966); Chem. Abstr., 65, 7266b (1966). (860) Hayden, A. L., Brannon, W. L., J . Ass. Ofic. Anal. Chem., 50 ( 3 ) , 674-5 (1967). (861) Hayden, A. L., Brannon, W. L., Yaciw, C. A., ibid., 49 ( 6 ) , 1109-53 ( 1966). (862) Haywood, P. E., Homer, M. W., Rylance, H. J., Analyst (London), 92 ( l l O O ) , 711-13 (1967). (863) Head, W. J., J . Pharm. Sci., 55, 1321 (1966). 1864) Healton. D. C.. Davidson. A. W.. J.‘Ass. Ogic: Anal. Chem., 49 (4),880-4 11966\. (865) Heding, H., Acta Chem. Scand., 20 ( 7 ) , 1743-6 (1966); Chem. Abstr., 66, 22251s (1967). (866) Heider. J. G., Bronk. J. R.. Biochim. Biophys. Res. Commun., 95‘ (a), 353 (1965);Anal. Abstr., 13, 5069 (1966). (867) Helmkamp, R. W.,Contreras, hI. de L. A., Bale, W. F., J . Nucl. Med., 7 ( 7 ) ,491-500 (1966). (868) Helou, J. H., Rev. Fac. Farm. Bioauim. Univ. Suo Paulo. 4 (21. 349-84 i1966); Chem. Abstr., 67; 47126; (1967). (869) Hemerich, F. G., Advan. Chromatogr., 1 , 3-60 (1965). (870) Hemphill, D. G., Diss. Abstr., B, 27 (9),3008 (1967);Chem. Abstr., 67,57281e f14671,. (1967). (871) Hennart, C., Talanta, 12 ( 4 ) , 420 11965). (872) Hennart, C., Berteleau, G., Chim. Anal., 48 (9), 493 (1966);Anal. Abstr., 14, 7560 (1967). (873) Hentrich, K., Pfeifer, S., Pharmazie, 21 ( 5 ) , 296 (1966); Anal. Abstr., 14, 5714 11967). (874) Ibid., 22 ( l l ) ,666-7 (1967); Chem. Abslr.. 68. 5330li (1968). --(873) Hkntrich, K., Pfeifer, S., Pharm. Zentralh. Deut., 106 ( l l ) ,735-45 (1967); Chem. Abstr., 68, 81437b (1968). (876) Henwood. C . R., Nature, 216 (5119). 1039-40 (1967). ‘ 1877) Hermans. R. B.. KamD. P. E.. Pharm. Weekblad., 102 (44j, ’ 1123-4i (1967);Chem. Abstr., 68, 161672 (1968). (878) Herr, E. B., Redstone, RI. O., Ann. N. Y . Acad. Sn’., 135 ( 2 ) , 940-6 (1966); Chem. Abstr., 65, 7270a (1966). (879) Hesse, M., Bild, N.,Schmid, H., Helv. Chim. Acta, 50 ( 3 ) ,808-13 (1967); Chem. Abstr., 67, 2639s (1967). (880) Heusser, D., Deut. Apotheker-Ztg., 103 ( 3 3 ) , 1101 ( 1 9 6 5 ) ;Anal. Abstr., 13, 7072 (1966). (881) Ibid., 106 ( 1 3 ) ,411-12 (1966);Chem. Abstr., 65, 3670e (1966). \ - - - - I -

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(882) Heydenreich, K., Pharmazie, 21 (9), 505-36 (1966); Anal. Abstr., 15, 2234 (1968). (883) Ibid. (lo), p 577; Anal. Abstr., 15, 2234 (1968). (884) Higuchi, T., Kato, K., J . Pharm. Sci., 55 (lo), 108C-4 (1966). (885) Higuchi, T., Michaelis, A., Tan, T., Hurwitz,, A.,. ANAL.CHEM.,39 (81, 974-9 (1967): 18861 -, Hill. V. B.. Martin. E. E.. J. Ass. Ofic. Anal. Chem., 50 (l), 42-5’0967). (887) Hiller, K., Keipert, M., Linzer, B., Pharmazie, 21 (12), 713-51 (1966); Chem. Abstr 67, 14798m (1967). (888) Hkavama, K., Inoue, K.,’ J . Pharm. Sb., 56 74), 444-9 (1967). (889) Hirtz, J., Labo-Pharma, 1967 (157), pp 23-8; Chem. Abstr., 67, 102808~ I - -

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(890) Hocman, G., J . Chromatogr., 21 (3), 413 (1966). (891) Hoehlein, H., Pharmazie, 21 (8), 464-6 (1966): Chem. Abstr.. 66. 5799e (892jIhid., 22 (l), 27-9 (1967); Chem. Abstr., 66, 1 0 8 3 0 1 ~(1967). (893) Hoerhammer, L.,Wagner, H., Hoelzl, J.. Reber. H.. Deut. Apotheker-Zta.. 107 (49), 1793-5 ‘(1967); Chem. Ab&.; 68, 7 2 2 7 6 ~(19681.

!rm. Prax. (Berlin), 1965 (10). ~ ~ ‘ 2 1 7 - 2 0Anal. : Abstr.,, 14., 972 (i967j.(896) Hofmann, A., Pharm. Weekblad., 100 (44), 1261-83 (1965); Anal. Abstr., 14, 970 (1967). (897) Holbrook, A., Scales, B., Anal. Biochem., 18 (l),46-53 (1967). (898) Hollifield, II. C., Winefordner, J. D., Anal. Chim. Acta. 36 (3). 352 (1966): Anal. Abstr., 15, 341 (1968). (899) Hollifield, H. C., Winefordner, J. D., Talanta, 14 (l),103 (1967); Anal. Abstr., 15, 2151 (1968). (900) Holt, R. J., Stewart, G. T., Biochim. Biophys. Res. Commun., 100 ( l ) , 235 (1965); Anal. Abstr., 13,5138 (1966). (901) Holtzman, J. L., Anal. Biochem., 13 (l), 66 (1965). (902) Hoodless, R. A., Analyst, 91 (1082), 333-4 (1966). (903) Hopes, T. &I., J. Ass. Ofic. Anal. Chem., 49 (4), 840-50 (1966). (904) Horak, P., Cesk. Farm., 16 (5), 2323 (1967);Chem. Abstr., 67,940412 (1967). (905) Horak, P., Kudrnac, S., ibid., 15 (9), 483-90 (1966); Chem. Abstr., 66, 79622y (1967). (906) Horii, Z., Yamawaki, Y., Tamura, Y., Saito, S., Yoshikawa, H., Kotera, K., Chem. Pharm. Bull. (Tokyo), 13 (ll), 1311-18 (1965); Chem. Abstr., 67,73727k (1967). (907) Horn, W., Kny, L., Richter, J., Arzneimittelstandardisierung, 6, 515-17 (1965); Chem. Abstr., 66, 140540 (1967). (908) Hornicek, B., Cesk. Farm., 15 (5), 225-8 (1966); Chem. Abstr., 66, 5804y (1967). (909) Hornin E. C., Vanden Heuvel, W. J. A., Riv. %al. Sostanze Grasse, 42 (9), 418-29 (1965); Anal. Abstr., 14, 331 (1967). (910) H o r o d e c k a , M., Oskierko, H . , Wieclawek, B., Kowszyk-Gindifer, Z., Chem. Anal. (Warsaw), 10 (5), 881 (1965); Anal. Abstr., 14, 986 (1967). (911) Horodecka, M., Wieclawek, B., ibid. (6), p 1363;Anal. Abstr., 14,, 1651 (1967): (912) Hosogai, Y., Kawashiro, I., Ezsez Shikensho Hokoku, 82, 103-5 (1964) ; Chem. Abstr., 65, 86719 (1966). (913) -Houle. M. .J.. Powell. R. L..’ Anal. ~ Biochem., ’13 - - -

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(196R’I.

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(958) Ibid. (4), pp 16-21; Chem. Abstr., 67, 120206b (1967). (959) Iliev, &I.,Gulubova, Tsv., ibid., 16 (2), 29-32 (1966); Chem. Abstr., 65, 134549. (1966). (960) Imanari, T., Tamura, Z., Chem. Pharm. Bull. (Tokyo), 15 (6), 896-8 (1967); Chem. Abstr., 67,120219h (1967). (961) Imhoff, D. W.,Diss. Abstr., B, 27 ( l l ) , 3811-12 (1967). (962) Inazu, K., Nakanishi, S.,Yamamoto, R., Bitamin, 36 (l),31-4 (1967); Chem. Abstr., 67, 67653s (1967). (963) Ibid., 37 ( 2 ) , 170-4 (1968); Chem. Abstr., 68, 62642y (1968). (964) Ibid., pp 175-81; Chem. Abstr., 68, 626432 (1968). (965) Inazu, K., Yamamoto, R., ibid., 34 13). 328-33 (1966): Chem. Abstr.,. 65,. 18432b (1966). (966) Inglese, R., Corriere Farm., 21 (13), 316-17 (1966); Chem. Abstr., 6 7 , 4 7 1 1 9 ~ (1967). (967) Inouye, H., Tokura, K., Araki, Y., Yakugaku Zasshi, 87 (l),88-94 (1967); Chem. Abstr., 66, 105073s (1967). (968) Inouye, H., Ueda, S., Araki, Y., Shimizu, H., ibid. (2), pp 109-13; Chem. Abstr., 67, 25423m (1967). (969) Inouye, H., Ueda, S., Araki-Takebe, Y., J. Chromatogr., 25 (l),167-8 (1966). (970) Inozemtseva, I. I., Kleiner, G. I., P a n i n a , M. A., K a m o k i n a , Z. F., Andreeva, M. K., Strukov, I. T., Antibiotiki, 11 (6), 497-501 (1966); Chem. Abstr., 65, 8668h (1966). (971) Ioanid, N., Armasescu, L., Bem, M., 1Farmacia (Bucharest), 13 (8), 459 (1965): Anal. Abstr.. 13. 7088 (1966). (972) Ioffe, R. A,, Lab. Delo, 1967 (l),p 47: Anal. Abstr., 15, 2150 (1968). (973) Ionescu-Solomdn, I., Constantinescu, T., Farmacia (Bucharest), 13 (2), 101-5 (1965); Chem. Abstr., 63, 4095h (1965). (974) Ionescu-Solomon, I., Constantinescu, T., Enache, S., Gamenti, V., Rev. Chim. (Bucharest), 17 (S), 490-3 (1966); Chem. Abstr., 66, 40752r (1967). (975) Ionescu-Stoian, P., Florea, V., Bojor, O., Cisa, V., Pharmazie, 21 (6), 350-2 (1966); Chem. Abstr., 65, 13454h (1966). (976) Iritani, N., Miyahara, T., Yano, K., Kitano, S., Yakugaku Zasshi, 87 (ll), 1427-9 (1967); Chem. Abstr., 68, 53314r (1968). (977) Iritani, N., Tanaka, T., Ogawa, K., ibid., 86 (ll), 1112-14 (1966); Chem. Abstr., 66, 690029 (1967).

(1008) Johnson, C. A., Mfg. Chemist, 36 (9), 80 (1965). (1009) Zbid., 37 (l),58 (1966). (1010) Zbid. (5), p 69. (1011) Zbid. (lo), p 58. 11012) Johnson. G. A.. Boukma. S. J..' ' A n d . Biocheh., 18 (l),143 (1967). (1013) Johnston, E. J., Jacobs, A. L., J. Pharm. Sci., 55 (5), 531 (1966). (1014) Jombik, J., Majer, J., Schiller, P., Cesk. Farm., 13 (5), 241-4 (1964);Chem. Abstr., 63, 5453e (1965). (1015) Jones. €3. 34.. Ratcliffe. R. J. hi.. ' Stevens, S.'G. E., j.Pharm.'Pharmacol; Suppl., 17, 52s (1965). (1016) Jones, F. B., J . Ass. O$c. Anal. Chem., 49 (3), 674 (1966). (1017) Jonsson, P., Samuelson, O., ANAL. CHEM.,39 (lo), 1156-8 (1967). (1018) Jonsson, P., Samuelson, O., Sci. Tools, 13 (2), 17 (1966). (1019) Jordan, W., Scheuer, P. J., J . Chromatogr., 19 fl), 175 (1965). (1020) Joshi, V. B., Krishnan, S., Sarasimhachari, N., Hindustan Antibiot. Bull., 9 ( l ) , 16-22 (1966); Chem. Abstr., 66, 68885k (1967). (1021) Josselin, J., Neuzil, E., Bull. Mem. Fac. Mixte Med. Pharm. Dakar, 11,12331 (1963);Chem. Abstr., 63,4094b (1965). (1022) J . Pharm. Sci., 54 (6). 909-10 (1965). (1023) Ibid. ( i ) p, 1045. 11024) Zbid. 19). D 1338. (1025) Zbid., 55'(6), 618-19 (1966). (1026) Zbid., pp 620-2. (1027) Zbid. ( i )p, 726. (1028) Zbid. (9), p 956. (1029) Juhl, I., Waarst, V., Arch. Pharm. Chem., 74 (21), 887-90 (1967); Chem. Abstr.. 68. 245740 119681. (1030) Jung, L., Cordier; P., Bull. SOC. Pharm. Strasbourg, 8 (2), 89-95 (1965); Chem. Abstr., 66, 31992s (1967). (1031) Jung, Z., Jungova, M., Cesk. Farm., 15 ( i ) ,341-8 (1966); Chem. Abstr., 66, 31986t (1967). 11032) Jusiak, L., Acta Polon. Pharm., 23 (3), 247-51 (1966); Chem. Abstr., 66, 5718b (1967). (1033) Jusiak, L., Soczewinski, E., Waksmundzki, A., Diss. Pharm. Pharmacol., 18 (5), 479-83 (1966); Chem. Abstr., 67, 3638010 (1967). (1034) Juul-Christensen, E. K., VOS, T., Huizinga, T., Pharm. Weekblad, 100 (16), 517 (1965);Anal. Abstr., 13,4399 (1966). (1035) Kachani, Z. F. C., Zh. Anal. Khim., 213 (6), 427 (1965); Anal. Abstr., 14, 1649 (1967). (1036) Kacamarek, F., Ostrowska, B., Zurawski, P., Herba Pol., 12 (4), 260-5 11966);Chem. Abstr., 67,111376e (1967). (1037) Kaess, A., Mathis, C., Ann. Pharm. Fr., 23 ( 1 2 ) , 739-47 ( 1 9 6 5 ) ; Chem. Abstr., 65, 571c (1966). (1038) Zbid.; 24 (12),753-62 (1966);Chem. Abstr., 67, 14874h (1967). (1039) Kaga, S. I., Oya, K., Arch. Pract. ( 1 067),. Pharm., 26 (11, 11 (1966); Anal. Abstr., (1002) Jensen, R., Muraine, J., Bull. SOC. 14, 3549 (1967). Pharm. Bordeaux, 106 (3), 124-34 (1967); (1040) Kagan, F. E., Farm. Zh. (Kiev), 21 Chem. Abstr., 68, 89907a (1968). (6), 14-20 (1966); Chem. Abstr., 66, (1003) Jiles, L. A. A., Anales Fac. Quim. 98529q (1967). Farm., Univ. Chile, 17, 142-9 (1965); (1041) Kagan, F. Yu., Koget, T. O., Farm. Chem. Abstr., 66, 98509h (1967). Zh. (Kiev), 21 ( l ) ,23-7 (1966); Chem. (1004) Jiracek, V., Ponert, J., CzechoAbstr., 65, 53049 (1966). slovakian patent 119,501 (Aug 15, 1966); (1042) Ibid. (2), pp 24-7; Chem. Abstr., 65, Appl. December 3, 1963, 2 pp; Chem. 3671h (19661. Abslr., 66, 118900j (1967). (1043) Kagan, F. Yu., Vaisman, G. A,, (1005) J o h a n n e s e n , B., Aslaksen, B., ibzd., 22 (3), 15-23 (1967); Chem. Abstr., Thom, E., Medd. Norsk Farm. Selskap, 68,245692 (1968). 28 (12), 869 (1966); Anal. Abstr., 15, (1044) Kaganskii, 51. I f . , Kravchenko, V. 2260 (1968). F., Belousova, G. M., Med. Prom. SSSR, (1006) Johnson, C. A,, Advan. Pharm. Sci., 20 (ll),49-50 (1966); Chem Abstr., 67, 2, 323-310 11967); Chem. Abstr., 68, 940579 ~1967). 43167n (1968). (1007) Johnson, C. A,, et al., Analyst (1043) Kahan. J.. Scand. J . Clin. Lab. Zn(London), 92 (l094i, 328-42 (19671; uest., 18 (6), 679 (1966);Anal. Abstr., 15, Chern. Abstr., 67, 2541771 (1967). 2179 (1968).

(978) Irudayasamy, A,, Natarajan, A. R., Zndzan J . Chem., 3 ( i ) ,327-8 (1965); Anal. Abstr., 13, 6475 (1966). (979) Ishida, N., Kumagai, K., Niida, Ta., Tsuruoka, T., Yumoto, H., J . Antibiot. (Tokyo), Ser. A, 20 (a), 66-71 (1967); Chem. Abstr., 66, 1 0 8 1 9 7 ~(1967). (980) Istratescu-Guti, L., Farmacia (Bucharest), 16 ( l ) , 35-8 (1968); Chem. Abstr., 68, 89892s (1968). (981) Istratescu-Guti, L., Radian, V., ibid., 15 (6), 347-52 (1967);Chem. Abstr., 67, 84900n (1967). (982) Itagaki, T., Tsukahara, T., Bitamin, 36 (l), 21-7 (1967); Chem. Abstr., 67, 763409 (1967). (983) Itokawa, Y., Inoue, K., ibid. (6), p 544-7; Chem. Abstr., 68, 33248u (1968f: (984) Ivanov, N., Boneva, A., Bulgar. Tyzctyun, 11 (4), 30-2 (1966); Chem. Abstr., 65, 8668.f (1966). (985) Ivanov, V., Nikolov, N., Yaneva, A., Farmatsiya (Sofia), 17 (2), 20-7 (1967); Chem. Abstr., 67, 1113642 (1967). (986) Iwasa, J., Naruto, S., Utsui, Y . , Yakugaku Zasshi, 86 ( 5 ) , 396-9 (1966): Chem. Abstr.. 65. 5302c 11966). (987) Jablonowski,' W.,Farm. Polska, 23 i l ) , 51-5 (1967);Chem. Abstr., 67,57278~' (1967). (988) Jacin, H., Mishkin, .4.R., J . Chromatogr., 18, 170 (1965). (989) Jacobs, A. L., Dilatul-h, A. E., Weinstein, S., Kindheuser, J. J., J . Pharm. Sci., 55 (9), 893-5 (1966). (990) Jahnsen, V. J., ASAL. CHEM., 39 ( l ) ,141 (1967). (991) Jambor, B., Horvath, I. P., Institoris, L., Acta Chim. Acad. Sci. Hung., 53 ( l ) , 85-96 (1967); Chem. Abstr., 68, 8 9 8 9 6 ~(1968). (992) J a n i c k i . C. A , . Brenner. R . J.. Schwartx, B: E., J . Pharm. Sci.', 57 (3); 451-5 (1968). (993) Janitzki, U., Deut. 2. Ges. Gerichtl. Ned., 57 (1-2), 352-6 (1966); Chem. Abstr., 65, 8671e (1966). (994) Jankov. L.. Pharmazie. 22 110). 5687 1 (1967);' Chem. Abstr.; 68, 3 3 2 2 9 ~ 11968). (995) -Janku, J., Janata, J., Zyka, J., Cesk. Farm., 15 (2), 83 (1966); Anal. Abstr., 14, 3517 (1967). (996) Jardetzky, O., Naturwissenschajten, 54 (7), 149-55 (1967); Chem. Abstr., 67, 67@3Qn f l Ofi'i) '""I 19971 Javasankar. N. P.. Bhat.. J. V.. . -4nal. Biochem..' 15 13'1. 454 11966). (998) Jayaswal, S. B., Basu, N K , Zndzan J . Pharm., 29 (4), 132-4 (1967); Chem. Abstr., 67, 8 4 8 9 4 ~(1967). (999) Jeffrevs, J. A. D., J . Chromatoor., , 21 ( I ) , i i g (1966). ' (1000) Jelliffe, R. W.,Jackson, D., Page, C. J., Morgan, S., J. Lab. Clin. Med., 67 (4), 694 (1966). (1001) Jelliffe, It. W.,Page, C. J., EsCamilla, E. J., Morgan, S. L., Stephinson, R. G., J . Chromatogr., 27 (l), 172-9 ~

\ L U " ' / .

(1046) Kain, 54. L., Commiris, B. T., Dixon-Lewis, G., Nunn, J. F., Brit. J . Anaesthesia, 39 (5), 425-31 (1967); Chem. Abstr., 67, 6 7 6 7 5 ~(1967). (1047) Kaiser, D. G., Bowman, B. J., Forist, A. A., AXAL.CHEM.,38 (8), 977 (1966). (1048) Kaiser, F., Arch. Pharm., (Weinheim), 299 (3), 263 (1966); Anal. Abstr., 14, 4239 (1967). (1049) Zbid., 300 (3), 206-10 (1967); Chem. Abstr.. 67. 5 7 2 5 0 ~(19673. (1050) Zbid.', pp 301-6; Chem. Abstr., 67, 5 7 2 4 9 ~(1967). (1051) Kaistha, K. K., French, W.K.,J . Pharm. Sci., 57 (3), 459-64 (1968). (1052) Kakac, B., Mnoucek,K., Semonsky, M., Zikan, V., Cerny, A., Pharmazie, 20 f5), 320 (1965); Anal. Abstr., 13, 5162 (1966). f1053) Kakac, B., Sarsunova, M., Ba, T. T. H., Vachek, J., ibid., 22 14), 202-5 11967);Chem. Abstr., 67,111487s (1967). f1054) Kakemi, K., Sezaki, H., Inoue, S., Yakugaku Zasshi, 85 (8), 674 (1965); Anal. Abstr.. 14. 1006 (1967). (1055) Kakol, 'H.j 'Bogucka, J.,'Gajcy, H., Diss. Pharm., 16, 237-40 (1964); Chem. Abstr., 65, 86758 (1966). (1056) Kalember-Bajic, D., Filipovic, D., Uvodic, F., Arhiv Farm. (Belgrade), 15 (2), 147-51 (1965); Chem. Abstr., 66, 689633' (1967). (1057) Kalinowska, Z. E., Pharmazie, 22 fl),1-3 (1967):Chem.Abstr., 66,108264r (1967). (1058) Kalinowska, Z. E., Hasztar, H., Farm. Polska, 23 ( l ) ,48-50 (1967);Chem. Abstr., 67, 67659y (1967). (1059) Zbid. (5-6),pp447-50; Chem.Abstr., 67, 120229m (1967). (1060) Kalinowska, Z. E., Hasztar, H., Jurczyk, J., ibid. (3), pp 261-3; Chem. Abstr., 68, 6230a (1968). (1061) Kalinowska, Z. E., Najman, L., ibid. 22 (6), 406-10 (1966);Chem. Abstr., 66. 3 1 9 8 9 ~11967). (l06i) Kalinowska, Z. E., N'aprzko, J., ibid. (lo), pp 728-30; Chem. Abstr., 67, 57282.f (1967). (1063) Kalinowski, K., ibid., 21 (23-24), 914 (1965);Anal. Abstr., 14,4253 (1967). (1064) Zbid., 23 (l), 18-23 (1967); Chem. Abstr., 67, 14867h (1967). (1065) Kalinowski, K., Czlonkowski, F., Acta Polon. Pharm., 24 (l),31-6 (1967); Chem. Abstr., 67, 67632j (1967). (1066) Kalnina, M., Spolite, R., Gofman, B. E., Piperazin, Akad. Nauk. Latv. SSR, Znst. Ora. Sin.. 1965. 125-30: Chem. dbstr., 66, 43537h- (1967). (1067) Kaludin, Iliya, Vet. Med. Nauki (Sofia),4(7),109-15 (1967);Chem.Abstr., 68, 33233k (1968). (1068) Kaluzhenko, R. K., Miirchakova, A. F., Lab. Delo, 1966 ( 7 ) , 392-3; Anal. Abstr., 14, 6995 (1967). (1069) Kaniinski, B., Sobotka-Wierzbowicz, J., Farm. Polska, 23 (3), 221-6 (1967): Chem. Abstr., 68, 2 4 5 7 9 ~(19681. (1070) Kamm, J. J., Van Loon, E. J., Clin. Chem., 12 ( l l ) ,789 (1966). (1071) Kammereck, R., Lee, Wen-Hui, Paliokas, A., Schroepfer, G. J., J . Lipid Res., 8 (3), 2s"-4 (1967). (1072) Kamp, Pha/m. Weekblad, 101 (B), 181 (1966,, $naZ. Abstr , 14, 4255 11967), \ - - -

(1073) Ibid. (39), pp b57-62; Chem. Abstr., 65. 18429d 11966). (10741 Kamp, IT.,and Onderberg, W.J. If.,Pharm. Weekbl. 101 (48), 1077-83 (1966). Chen. dbstr., 66, 31977r (1967). (1075) Kamp,K., andOort, A.van, Pharm. Teekbl. 102 (49), 1295-301 (1967); Chem. Abstr., 68, 432131 (1968). (1076) Kaniewska, T., Zyzynski, W., ass. P h a r m . Pharmacol., 18 (5), 511-14 (1966); Chem. Abstr., 67, 14871e (1967). VOL. 41, NO. 5, APRIL 1969

231 R

.077) Kanno, S.,Watanabe, S., Takuma, M., Yakuzaigaku, 25 (4), 12-18 (1965); Chem. Abstr., 65, 18428h (1966). 078) Kanter, S. L., Clin. Chim. Acta, 17 ( l ) , 147-8 (1967); Chem. Abstr., 67, 84940a (1967). 079) Kaptionak, A. E., Biernacka, E., Pazdera, H. J., Technicon Symp. Znd, N . Y . London, 1965, pp 27-33 (Pub. 1966); Chem. Abstr., 68, 62173 (1968). 080) Karas-Gasparec, V., Acta Pharm. Jugoslav., 16 (3), 85 (1966);Anal. Abstr., 14, 6395 (1967). 081) Karas-Gasparec, V., Hankonyi, V., Farm. Glasnik, 21, 341 (1965); Anal. Abstr.. 13. 7085 11966). (1082) K a r a t o d o r o v , K.,Farmatsiya, (Sofia), 16 ( 5 ) ,41-4 (1966);Chem. Abstr., 66, 68970j (1967). (1083) Karawya, 11.S., Ghorab, G., Zaki, N., Wagdi, S.,Amer. Perfumer Cosmet., 82 (4), 45-6 (1967); Chem. Abstr., 67, 14889s (1967). (1084) Karawya, 11. S.,Wahba, S. K., Koznian, A. R., J . Pharm. Pharmawl., 19 ( 5 ) , 332-4 (1967). (1085) Karlsen, J., Norg. Apotekerforen. Tidsskr., 74 (13), 251-60 (1966); Chem. Abstr., 65, 14051s (1967). 11086) Karnisauskaite. G.. Bernshtein. V. K.,’Aptechn. Delo, 15 (4), 39-43 (1966); Chem. Abstr., 65, 15162f (1966). 087) Karpov, 0. N., Tr. Vses. Arauchn.Issled. Inst. Khim. Reaktivov Osobo Chist. Khim. Veshchestv, 26, 269-72 (1964) ; Chem. Sbstr., 66, 79653j (1967). 088) Karpova, L. K., Farmatsiya (Moscow), 16 (4), 39-41 (1967); Chem. dbstr., 67, 9405la (1967). 089) Kartseva, V. D., Yakhontova, L. F., Isaeva, S. L., Bruns, B. P., Antibiotiki. 12 (9).772-5 (1967):Chem. Abstr.. 68, 33156n (1968). 090) Kabe, Y., Yuizono, T., Kataoka, I f . , Miyata, T., Kumamoto Pharm. Bull., 1965 (6), p 382; Anal. Abstr., 13, 6506 (1966). (1091) Kassau, E., Deut. Apotheker-Ztg., 106 (50), 1833-5 (1966); Chem. Abstr., 66, 98524~(1967). (1092) Kassem, AI. 8.,Kassem, A. .4.,ElXimir, A. E. V., Pharm. Ztg., 111 (48), 1792-4 (1966); Chem. Abstr., 66, 68997y (1967). (1093) K a s s e m , hi. A . , S i n a , A . , E l Sourady, H. A., Farmaco, Ed. Prat., 22 (3), 152-8 (1967); Chem. Abstr., 66, 118882e (1967). (1094) Kassem, 11.A., Sin&,A., Youssef, M. K., Pharm. Ztg., 112 (6), 221-3 (1967); Chem. Abstr., 67, 1 4 8 1 9 ~(1967). (1095) Kasymov, Sh. Z., Aripov, Kh. N., Shakirov. T. T.. Yunusov. S. Yu., Khim. Prir. Soedin, 3 ( 5 ) , 352-3‘ (1967); Chem. Abstr., 68, 6205w (1968). (1096) Kataoka, AI., Miyata, T., Yogi, K., K a s e , Y., Chern. Pharm. Bull. (Tokyo), 15 ( 5 ) , 701-3 (1967); Chem. Abstr., 67, 67652r (1967). (1097) K a t a y a m a , T., Ikeda, H., Sci. Papers Inst. Phys. Chem. Res. (Tokyo), 60 (3), 85-9 (1966); Chem. Abstr., 66, 58863n 11967). (1098) Kat?, h., Doihara, T., Sakai, H., Takahashi, K.. Nippon Senbaa Kosha Chuo Kenkyusho Kenkyu Hokoku, 108, 361-4 (1966); C‘hem. Sbstr., 66, 1 8 8 1 7 ~ (1967). (1099) Katsui, G., Omae, X,Bitamin, 34 (2), 256-67 (1966); Chem. Abstr., 65, 1842% (1966). (1100) Katz, J., Anesthesiology, 27 (6), 835-7 (1966); Chem. iibstr., 66, 2 2 1 7 3 ~ (1967). (1101) Katz, M. A., Tadjer, G., Aufricht, UT.A., J . Chromatogr., 31 (2), 545-6 119fi7)

(1102,.Ksufmann, W., Pharmazie, 22 (l), 29-30 (1967); Chem. Abstr., 66, 108320s (1967). 232 R


(1103) Kawabata, T., Shibuya, K., Suzuki, T., Nippon Suisan Gakkaishi, 31 ( 5 ) , 350-6 (1965); Chem. Abstr., 66, 1188199 11Qfi7i

I - - - . / .

(1104) Ibid., pp 357-64; Chem. Abstr., 66, 118820h (1967). (1105) Kawai, S., Hashiba, S., Eisei Shikensho Hokoku. 82. 67-9 (1964’1: , . Chem. Abstr., 65, 8670i (i966). (1106) Kawai, S., Nagatsu, T., Imanari, T., Tamura, Z., Chem. Pharm. Bull. (Tokyo), 14 (6), 618-21 (1966); Chem. Abstr., 65, 104269 (1966). (1107) Kawamura, K., Yakugaku Zasshi, 87 (4), 394-400 (1967) ; Chem. Abstr., 67, 676519 (1967). (1108) Kawamura, K., Onishi, R., ibid. ( 7 ) ,pp 850-6; Chem. Abstr., 67, 84925% (1967). (1109) Kay, H. L., J . Pharm. Belg., 20 (11-12), 463-6 (1965); Chem. Abstr., 65, 569h (1966). (1110) Kaye, R. C., Seager, H., J . Pharm. Pharmacol., 20 (l),54-7 (1968). (1111) Kazarinov, 11.O., Dzyuba, X. P., Med. Prom. SSSR, 20 ( 5 ) , 50-2 (1966); Chem. Abstr., 65, 10426f (1966). (1112) Kazarinov, K. 8., Dzyuba, N. P., Farmatsiya (Moscow), 16 (2), 52-4 (1967); Chem. Abstr., 67, 149019 (1967). (1113) Keay, G. R., Analyst (London), 93 (11021, 28-33 (1968). (1114) Kechatova, N. A, Perel’son, 31. E., Khim.-Farm. Zh., 1 ( 5 ) ,48-9 (1967); Chem. Abstr., 67, 67657w (1967). (1115) Kedzia, B., Golcz, H., Schulz, M., Kedzia, W.,Farm. Polska, 23 (3), 22732 (1967); Chem. Abstr., 68, 62661d (1968). (1116) Keiner, J., H u e t t e n r a u c h , R., Poethke, W., Arch. Pharm. (Reinheim), 300 (lo), 840-4 (1967); Chem. Abstr., 68, 6218c (1968). (1117) Keiner, J., H u e t t e n r a u c h , R., Poethke, W.,Pharm. Zentral. Deut., 105 ( l l ) , 705-11 (1966); Chem. Abstr., 66, 31940y (1967). (1118) Kelemen-Kuettel, I., Kerenyi, I., Acta. Pharm. Hung., 37 (2), 60-6 (1967); Chem. Abstr., 66, 1083148 (1967). (1119) Kellv, C. A., Enycl. Ind. Chem. Anal., 5, “355-421 (1967). (1120) Kemula, W.,Sybilska, D., Chlebicka, K., Rocz. Chem., 39 ( l o ) , 1499 (1965); Anal. Abstr., 14, 1002 (1967). (1121) Kendall, C. E., Analyst, 91, 284 (1966). (1122) Kevei, E., Petro, O., Szarfoldi, J., Elelmiszertudomany, 1967 (1-2), pp 458 ; Chem. Abstr., 68, 62i40d (1968). (1123) Kharin, S. E., Kolcheva, R. A., Sakharn. Prom., 40 (4), 17-22 (1966); Chem. Abstr., 65, 7257f (1966). (1124) Khokhlova, Yu. M., Puchnina, A. V., Oparysheva, E. F., Golovkina, L. hi., Blinov, N. O., Izv. Akad. Nauk SSSR, Ser. Biol., 31 (3), 433-40 (1966); Chem. Abstr., 65, 3668b (1966). (1125) Khoury, A. J., Cali, L. J., J . Pharm. Sci., 56 (ll),1785-9 (1967). (1126) Khoury, A. J., Cali, L. J., Technicon Symp. Znd, N . Y . London, 1965, pp 22-6 (Pub. 1966) ; Chem. Abstr., 68,6226d (1968). (1127) Kieruczenko, A., Farm. Polska, 22 (8), 583-5 (1966); Chem. Abstr., 66, 40760s 119671. (1128) Ibid. (9j, pp 668-70; Chem. Abstr., 66, 4075921 (1967). (1129) Xiper, J. L., Kiger, J. G., Ann. Pharm. Fr., 24 (9;10), 593-605 (1966); Chem. Abstr., 66, i9643f (1967). (1130) Ibid., 25 (9-lo), 601-12 (1967); Chem. Abstr.. 68. 93277f (1968). (1131) Kim, C: D:, Shim. S.H., Suh, J. H., Yakhak Hoeji, 9 (1-2), 14-17 (1965); Chem. Abstr., 65, 151620 (1966). (1132) Kim, J.’S.,’Tucke;man, hi. hi., J . Pharm. Sci., 56 (lo), 1309-10 (1967).

(1133) King, R. E., Wragg, J. S., J. Pharm. Pharmacol., Suppl., 18, 22-7 (1966). (1134) Kinze, W.,Pharm. Praz. (Berlin), 1965 (ll),241-7; Anal. Abstr., 14, 1635 (1967). (1135) Kinze, W., Pharm. Zentralh. Deut., 104 ( l l ) , 705 (1965); Anal. Abstr., 14, 1629 (1967). (1136) Ibid., 105 (6), 365-8 (1966); Chem. Abstr., 65, 10427e (1966). (1137) Kirchner, J. G., “Technique of Organic Chemistry, Vol. XII: Thin-Layer Chromatography,” Interscience, New York, N.Y., 1967, 788 pp. (1138) Kirichenko, L. O., Farm. Zh. (Kiev), 21 (4), 43-7 (1966); Chem. Abstr., 65, 19929f (1966). (1139) Kirshbaum, A., Arret, B., J.Pharm. S i ,56 (4), 511-15 (1967). (1140) Kisbye, J., Dansk Tidsskr. Farm., 41 (4), 65-82 (1967); Chem. Abstr., 67, 63502u (1967). (1141) Ibid. (16), pp 103-19; Chem. Abstr., 68, 33152h (1968). (1142) Klantschnigg, P., Chiari, G., Teotino, U. M.,Farmaw, Ed. Prat., 21 (12), 688-99 (1966); Chem. Abstr., 66, 588711, (1967). (1143) Klebanov, G. S., Mednikova, L. N.,Ovcharova, A. D., Khim.-Farm. Zh., 1 (4), 49-52 (1967); Chem. Abstr., 67, 111363 (1967). (1144) Kyeinman, L. X.,Schriftman, H., J . Pharm. Sn’., 56 (4), 516-17 (1967). (1145) Klera, % Dudzik, I.,Z., Farm. Polska, 21 (19-20). 770-6 (1965): Chem. Abstr.. , 65. ‘5303c”(1966:. (1146) Kline,‘R. &I Golab, ., T., J. Chromatogr., 18 (2), 409 (1965). (1147) Klinge, D., Deut. Apotheker-Ztg., 106 (3),69 (1966);Anal. Abstr., 14,2686 (1967). (1148) Klinge, D., Pharm. Ztg., 112 (39), 1387-90 (1967);Chem. Abstr., 68,33251q (19681. (1149) Blocking, H. P., Pharmazie, 20 (ll), 737 (1965);Anal. Abstr., 14,1554 (1967). 11150’1 Klockine. H. P.. hfarkwardt., F.., ‘ Richter, M., %id. (9),p 5.54. (1151) Klotz, L., Rehfeld, S., Pharm. Zentralh. Deut., 106 (l),3-6 (1967); Chem. Abstr., 66, 68985t (1967). (1152) Knabe, J., Philipson, K., Arch. Pharm. (Weinheim), 299 (4), 321-30; (1966); Chem. Abstr., 65, 570h (1966). (1153) Kniseley, S. J., Throop, L. J., ANAL. CHEM.,38. 1270 (1966). (1154) Knizhnik, A.’E., Farm. Zh. (Kiev), 21 (6), 30-2 (1966); Chem. Abstr., 66, 98540m (1967). (1155) Knobloch, E., Cesk. Farm., 16 (2), 64 (1967); Anal. Abstr., 15, 2910 (1968). (1156) Knobloch, E., Intern. 2. Vitaminforsch.,37 (1),38-51 (1967);Chem.Abstr., 66, 1082912 (1967). (1157) Knuppen, R., Haupt, O., Breuer, H.. Steroids. 8 13). 403 (1966). (1158) Kobayashi; ’T,, &ami;, 34 ( 5 ) , 473-6 (1966); Chem. Abstr., 66, 140632 (1967). (1159) Ibid., pp 477-81; Chem. Abstr., 66, 1 4 0 6 4 ~(1967). (1160) h i d . , pp 482-4; Chem. Abstr., 66, 14065%(1967). (1161) K o b a y a s h i , T., J . V i t a m i n o l . (Kvoto’1. 13 (4:. 255-7 11967): Chem. Ab&., 68, 62742j (1968). (1162) Ibid., pp 258-64; Chem. Abstr., 68, 627439 (1968). (1163) Ibid., pp 265-7; Chem. Abstr., 68, 62744h (1968). (1164) Koch, H., Buchbauer, G., Oesterr. Apotheker Ztg., 21 (14), 194-8, 200-1 (1967); Chem. Abstr., 67, 2 5 4 1 8 ~(1967). (1169) Kodama.T.,Samejima,M.,Amano, F., Utsumi, I., J. Vitaminol. (Kyoto), 13 (4), 298-304 (1967); Chem. Abstr., 68, 62755n (1968). I

.

(1166) Koerber, G., Krankenhaus-Apotheker, 15 (l), 1-5 (1965); Chem. Abstr., 65,3674b (1966). (1167) Kofoed, J . , Fabierkiewicz, C., Lucas, G. H. VT.,J . Chromatogr., 23 ( 3 ) , 410 (1966). (1168) Koizumi, J., Yoichi, Y., Takemoto, T., Bunseki Kagaku, 15 ( 7 ) , 647-52 (1966); Chem. Abstr., 65,16794b (1966). (1169) Koizumi, J., Yoichi, Y., Ueno, M., ibid., pp 652-6; Chem. Abstr., 65, 16794c (1966). (1170) Kojima, S., Ichibagase, II., Arch. Pract. Pharm., 26 (l),46 (1966); Anal. Abstr 14,3556 (1967). (1171) kolb, H., Patt, P. ST'., Arznezm.Forsch., 15 ( 8 ) ,924 (1965); Anal. Abstr., 13, 6953 (1966). (1172) Kolodziejski, J., Kuleszyna, A., Luczkiewicz, I., Stecka, I,., Diss. Pharm. Pharmacol., 19 (4), 371-5 (1967); Chem. Abstr., 67, 102710g (1967). (11731 Kolusheva, A,, Niiiuo, S . ,Farmatsiya (Sofia), 16 ( 2 ) , 9-18 (1966); Chem. Abstr., 65, 16794e (1966). (1174) Kolusheva, A., Toiicheva, P., ibid. (4),pp 40-5; Chem. Abstr., 66, 31978s (1967). (1175) Kolusheva, A,, Vulkova, A., ibid. (5), pp 45-9; Chem. Abstr., 66, 689731~ (1967). (1176) Komatsu, AI., Okano, S., Bunseki Kagaku, 15 (lo), 1115-19 (1966); ('hem. Sbstr., 66, 79636.f (1967). (1177) Kondrat'eva, A. P., Bruns, EL P., K h h - F a r m . Zh., 1 (12), 30-7 (1967): Chem. Abstr., 68,'72247n' (1968j. (1178) Konecny, J., Tolgvessy, J., Chem. Zvesti, 20 (9), 692 (1966); Anal. Abstr., 15, 425 (1968). (1179) Konecny, J., Tolgyessy, J., Radiochem. Conf., Abstr. Pap., Bratislava, 1966, pp 36-7; Chem. Abstr., 68,16185d (1968). (1180) Konecny, J., Tolgyessy, J., B;:aun, T Acta Chim. Acad. Sci. Hung., 511 ( 3 ) , 245-9 (1967); Chem. Abstr., 66, 9115620 (1967). (1181) Koriecny, J., Tolgyesay, J., Sarsunova, hl., Fresenius' Z. Anal. C,kern., 232 (5), 343-6 (1967); Chem. Abstr., 68, 161S4c (1968). (1182) Korchagin, V. B., Lokshin, G . B., Nirenberchik, V. I., Antibiotiki, 1 1 ( l l ) , 1047-9 (1966); Chem. Abstr., 66,40745r (1 M i ) : ( l l 8 3 j Korchins'kii, I. T., F a r m . Z h . (Kiev), 22 (6), 21-3 (1967);Chern. Abstr., 68, 6275% 11968). (1184) Kormicki, J., llikolajek, E., .Diss. Pharm. Pharmacol.. 20 (1).87-91 11068): C'hen. Absir.. 68. d1464h (1968). (1185) Kornblum, 'S.S., Zoglio, i f . A.., J . Pharm. Sci., 56 (12), 1569-75 (1967). (1186) Kornhauser, A , , Perpar, ,Irch. Pharm. (Weinheini),298 15), 321 (1965); -4nal. Abstr., 13, 5129 (1966). (1187) Kornhauser, A, Perpar, lI.,Farm. Vestnik (Ljubljana), 18 (1-4),1-8 (1967) ; Chem. Abstr., 67, 1 2 0 2 0 7 ~(1967). (1165) Koshy, K. T., Conwell, R. C., Duvall, R. N., J . Pharm. Sci., 56 ( 2 ) , '26971 (1967). (1189) Xost, A. K., Iioronelli, T. V., Iideman, R. R., Sagitullin, R. S., Zh. Anal. Khim.,20 is), 845 (1965); Anal. Abstr., 14, 2189 (1967). (1190) Kost, A. K., Sagitullin, R. S., ~Sorbunov, V. I., Barinova, G. I., Kh.irn.Farm. Zh., 1 13). 14-22 (1967);Chem. Abstr., 67,67533c (1967). (1191) Kostolowska, M., KrowrzJ-nski, L., Wiecha, A., a s s . Pharm. Pharmacol., 19 ( 3 ) , 303-8 (1967); Chem. Abstr., 67, 102743~(1967). (1192) Kotsyurba, V. A,, Aptechn. Delo, 15 ( 3 ) , 67-71 (1966); Chem. Abstr., 65, 5299h (1966). (1193) Fotula, Z., Kaminska, A., ,%fed. Doszczadczalna Mikrobiol., 19 (4),381-7 (1567); Chem. Abstr., 68,72292~(1968).

(1225) Krogerus, V. E., Kristoffersson, E. R.. Kahela. P.. Farm. Aikakauslehti. 76 (516), 122-5 (1967); Chem. Abstr., '67, 1 2 0 2 0 3 ~(1967). 226) Kroman, H. S., Moskovitz, 11.L., Bender, S. R., Brest. A. N., J . Gas Chromatogr., 4 (4), 147 '(1966). 227) Krone, I., Reuter, G Pharm. Zentralh. Deut., 106 ( 7 ) , 425-40 (1967); Chem. Abstr., 67, 111469n (1967). 228) Krowczynski, L., Far?,'. Polska, 21 (23-24), 893-9 (1965); Chem. Atstr., 65, 2063c (1966). 229) Krowczynski, L., Krasowska, H., llakosz, A., Acta Polon. Pharm., 23 (6), 493-8 (1966); Chem. Abstr., 66, 1082142 (1967). (1230) Krug, H., Herba Pol., 11 (1-2), 7990 (1966); Chem. Abstr., 66, 108284~ i\-_-.,. 1967) (1231) Krupa, V., Xochova, ll., Zathureeky, L., Cesk. Farm., 16 (4), 184-6 (1967); Chem. Abstr., 68,62246 (1968): (1232) Krzecekow-ska, J . , Ann. Un,Lv. -If a r i a e C ti r i e-S k 1o d o w s k a , L ti b 1inPolonia, Sect. D , 19,343-7 (1964) (Pub. 1965); Chem. Abstr., 65,55119. (1966). (1233) Kubiak, E. J., J . Pharm. Sci., 57 ( 3 ) ,473-5 (1968). (1234) Kudymov, G. I., lIokrouz, 11.V., Kiseleva, A. A., Khim.-Farm. Zh., 1 ( l o ) , 61-4 (1967); Chem. Abstr., 68, 33246s (1968). (1235) Iiuehri, L., Pfeifer, S., Pharmazie, 22 ( I ) ,58-9 (1967); Chcm. Abstr., 263772 (1967). (1236) Kuendig, H., Anal. Biochem., 23 (11, 6-12 (19683. (1237) K u h n e r t - B r a n d s t a e t t e r , lT ., Grimm, H., Mikrochim. Acta, 1968 (l), pp 115-26; Chem. Abstr., 68, 532929 (1968). (1238) Ibid., pp 126-39; Chem. Abstr., 68, 53293h (1968). (1239) Kuleshova, AI. I., Sb. Nauchn. T r . Tsentr.-Aptechn. Nauchn.-Issled. Znst., 6, 114-19 (1964); Chem. Abstr., 65, 2063h (1966). (1240) Iiulesza, J., Turkiewicz, AI,, Acta Polon. Pharm., 24 (21, 177-82 (1967); Chem. .4bstr., 67, 84936d (1967). (1241) Kulesza, R., Farm. Polska, 21 (34),95-9 (1965); Chem. Abstr., 63,5454e (1965). flSA6,. (1242) Kulosof, ll.IJ., AnalesFarm. Hosp., ( l ' i i ~ j ~ I i r : ~ ~ z i l a i , I . , F a b r y , G . , . ~ c f a P h a r ~ r10 . (20j, 41-4 (1967); Chem. Abstr., 67, Hung., 37 (33, 128-30 (1967); Chem. 572iOa (1967). ilbsti., 67, 14885n (19ti7). (1243) Kuo, Feng-]Veri, Chou, Chien(1214) Kraus. L., Pereiivi, F.. Cesk. Farm.. Hung, Han, Li-Hsia, Liu, Ts'ui-Huan, 14 (Sj, 423'(1965); A i a i . Abstr., 14,986 HOU,Fu-Chung, Yao Hsiieh Hsueh Pao, (1967). 13 (4), 296 (1966); Chem. Abstr., 65, (1215) Iirause, R. T., J . .4ss. 03c. Anal. 10646f (1966). Chem., 50 (3j, 685-8 (1967). (1244) Kurayuki, Y., llizunoya, Y., Ko(1216) Kraushaar, A., Arzneim.-Forsch., jima, H., Yakugaku Zasshi, 86 ( l o ) , 890 16 (81,1088-90 (1966); Chem. Abstr., 65, 1966); Anal. Abstr., 15, 1064 (1968). 1993011 (1966). 45) Iiurlansik, L., Damon, C., Klein, (1217) Iiraushaar, L. A, Epstein, E., Zak, H.: Salim, E. F., J . Pharm. Sci., 56 f9), B., Clin. Chem., 12 ( 5 ) )282 1196G). 1160-1 (1967). (1218) Iirejci, Z., Acta Cniv., Paluckianae (1246) Kurlansik, L., Danion, C., Salim, Olomuc. Fwc. Med., 1966 143), 111-24; E. F., ibid., pp 1158-60. Chem. Abstr., 67, 148S7q (1967). (1247) Iiurlanick, L., Salim, E. F., ibid., (1219) lirekhova, ll.A., Vop. Med. Khini., 55 (12), 1457-9 (1966). 1 1 ( 2 ) , 60 (1965); '4nul. -4bstr., 13, 7034 (1248) Zbid.. 57 13). 475-7 (1968). j 1966). (1249) Iiuroda, K., Hashizume, G., Yaku(1220j Iirepska, H., Pakula, R., C l e m . gakuzasshi, 87 ( 2 ) ,148-58 (1967);Chem. Anal. !Wwsawi!. 12 (21. 293-7 (1967): ,, Abstr., 66, 118897~(1967). C h m . Abstr., 68, 3323% ~1968). (1250) Ibzd., pp, 159-63; Chem. Abstr., 66, (1221) Kreshkov, A. P., Yarovenku, A. llS899r (1961). S . , Snyuahkiiia? E. S . . Zeleiiina, L. X., (1251) Ibid., pp 202-7; Chem. Abstr., 66, T T . Mosk. h - h i x . Teknnol. Ins[., 1965 1188989 (1967). 14&j, pp 43-7; - 4 7 ~ ~ 1ah . st^..^ 14, 3253 (1252) Ibid. ( 5 ) , pp 500-6; Chem. dbstr., (196; if 67. 57274e 11967). (1222) lirivut, E. -k, Perel'son, AI. E., (1253) K u r o d a , K . , H a s h i z u m e , G . , Khim.-Parm. Zh., 1 (21, 44-6 11967); Fukuda, IC., J . Pharm. Sci., 57 ( 2 ) , 250C h e w Sbstr., 67, 67617h (1967). 4 (1968). (1z23) Ibid., pp 46-8; Chem. Abstr., 67, I 634Sy (19ti7). (12.34) K u r o d a , IC., H a s h i z u m e , G . , (1224) Iirmelova, V., Rada, IC., Pharnz. Fukuda, X., Yakzcgaku Zasshi, 87 (lo), Zenlralh. Deut., 106 (Y), 595-8 (1967); 1175-83 (1967); Chem. Abstr., 68,24588, Chern. Abstr., 67, 111368d (1967). (1568).

(1194) Kovach, A,, Gyogyszereszet, 8, 45861 (1964); Chem. Abstr., 66, 22285m 11967). (1155) kovacs, E. P., Acta Pharm. Hung., 37 (4),150-8 (1967); Chem. Abstr., 67, 1 0 2 8 1 ~(1967). (1196) Ibid. (51, pp 198-203; Chem. Abstr., 67. 111477~11967). (119j) ~ o v a ' c s ,E. P., Matolcsy, E. z., ibzd., 36 (4),172-9 (1966); Chem. Abstr., 65, 15159e (1966). (1198) Koval'chuk, T. V., F a r m . Z h . (Kiev), 22 ( 3 ) ,24-9 (1967);Chem. ilbstr., 67, lll516a (1967j. (1199) ICovalenko, L. I., Aptechn. Delo, 15 (5), 56-8 (1966): C h e m . A b s t r . , 66, 1 4 0 6 2 ~(1967). (120071 Kovalenko, L. I., Farmalszva (MoaCOW), 16 ( 3 ) , 51-7 (1Y67), Che?/Z. Absir., 67, 676S8r 11967). (1201) Kovalenko, L. I., Farm. Zh. (Kiev), 21 (41, 48-52 11966); Chem. Abstr., 65, 19931b (1966). (1202) Koziol, J., Pr. Zakresu Tozcarozn. Chem., Wyzsza Szk. Ekon. Poznanzu Zesz. S a u k . , Ser. I , 26,91-102 (1966,; Chem. Abstr , 66, 6b960f (1966). (1203) Iiuziolowa, .%., i b z d . , pp 67-77; Che77i Abstr., 66, 5S861.k (1967). (1204) Ko~lov,N.E., Bernshtein, V. X., Farnlatszya f l I O S c O \ V ) , 16 (41, 42-5 11967); Chein. Abstr., 67, 940Xd 11967). (1205) XoLlova, E. F., Kuitanovich, I. lL, h'hlm.-Farnl Zh , 1 1 5 ) , 34-6 (1967), Chem Abstr., 67,6766% (1967). (1206) Kracmar, J., Cesk. Farm., 12 (9), 458-66 (1963); Chein. Absfr , 63, 5452d (1965). (1207, Nracmai, J., Pharniazie, 21 (4), 224-6 (1966); Chem. Abstr., 65, 6997d (1966). (1208) Bmcmar, J., Iiracniarova, J., Cesk. F a r m , 15 fl;, 16 (1966); Anal Abstr., 14,3522 (1967). (1206) Ibid. 13), pp 121-9; Chem. Abstr., 65. 366% f 1 9 A G i . (1210) ~r a c &i,' J ., K r a c m a r ov a , J ., Pharmazie, 22 18), 401-14 (1967); Chem. Abstr., 67 1202000 (1967). (1211) Xracmar, J., Kracmarovii, J., Sladkava, J., ibiti., 21 (S), 460-3 (1966); Chem. Abstr., 66,22229~1(1967). (1212) Krasnec, L., Kagy, A, Cesk. Farm., 14 (5): 21% 11965);Anal. Abstr., 13,5134

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rn

233 R

(1255)I h d . (12),pp 1562-8;Chem. Abstr., 68, 51452~(1968). (1256) Kusznieruk, M., Rarmuzinska, T., Farm. Polska, 22 ( 7 ) , 515-17 (1966); Chem. Abstr., 66, 492709 (1967). (1257) Kutlu, H., Istanbul Univ. Eczacilik Fak. Mecm., 1 (2),128-36 (1965);Chem. Abstr., 65, 86708 (1966). (1258) Kuzel, N. R., Coffey, H. F., J . Pharm. Sci., 56 (4),522-5 (1967). (1259) Kuznetsov, V. I.,Volkova, N. S., Khim-Farm. Zh., I 16). 41 (1967):Chem. Abstr., 67, 94031~11967). (1260) Kuzovkov, A. D., Lokshin, G. B., Zhdanovich, Yu. V., Hhryashcheva, K. >I Antibiotiki, ., 11 (5), 422-3 (1966); Chem. Abstr., 65, 3673d (1966). (1261) Kvapil, J., Liska, M.,Cesk. Farm., 15 15), 235 (1966);Anal. Abstr., 14, 5687 (1967). (1262) Ibid. (lo), p 517;Anal. Abstr., 15, 1091 (1968). (1263) Kyowa Habko Kogyo Co., Ltd., British patent 1,067,238; Appl. Oct. 8, 1964;Japanese appl. B u g 10,1963; Anal. Abstr., 14, 6877 (1967). (1264) Labadie, R.P., Svendsen, A. B., P h a r m . W e e k b l a d , 102 (lo), 169-71 (19671;Chem. Abstr., 67, 57249 (1967). (1265) Laboratories Albert Roland, Belgian patent 666,770 (Nov 16, 1965); Brit. appl. July 27,1964,16 pp; Chem. Abstr., 65, 367i.f(1966). (1266) Lach, J. L., Sawardeker, J. S., J . Pharm. Sci., 54 (3), 424-6 (1965);Chem. Abstr., 63, 4095a (1965). (1267)Lacroix, It., Guidollet, J., Zigliara, J., i l n n . Pharm. Fr., 23 (7-8), 513 (1965); Anal. AAbstr., 14, 1663 (1967). (1268) Lande, I. S.,de la, Harvey, J. A., J . Phnrm. Pharmacol., 17 (9), 589 (1965). (1269) Lange, W.E., Bell, S. A., J . Pharm. Sci.. 55. 386 (1966). (1270jLingley, IT. D., ANAL.CHm., 39, 199 (1967). (1271) Laniere. C. L.. Thunus. L.. Far-~ ?naCo,-Ek Prht., 22 ( i )359-402 , (1967); Chem. Abscr., 67, 84773y 1196i). (1272) Lapina, K. P.,Aptechn. Delo, 15 (3), 4i-52 (1966); Chem. ilbstr., 65, 12061e (1966). (1273)Larter, R. R.,A u s t r a l a s i a n J . Pharm., 47 (556), S33-5 (1966);Chem. Abstr., 67, 67621e (1967). (1274)Laszlo, T., Rev. Chim. (Bucharest), 17 (6),355-6 (1966);Chem. Abstr., 65, 15157h (1966). (1275)Laszlo, V.,Acta P h a r m Hung., 36 (5), 215-22 (1966);Chem. Abstr., 65, 1842811 (1965). (1276)Ibid. (6),pp 253-6;Chem. Sbstr., 66. 22272e 11967). (1278) Laszlovszky, J., Stiglmayer, 11. A., ibid. (4),pp 159-66;Chem. Abstr., 67, 102828b (1067). (1279)Lau, H. L., J . Gas Chromatogr., 4 (4),136 (1966). (1280) Laurent, O.,J . Pharm. Balg., 21 (11-12),589-91 (1966);Chem. dbsfr., 66, i9656n (1967). (1281) Lnycock, H.H., lllilley, 13. A., J . Pharm. Pharmacol., Suppl., 18, 9-11 (1966). (1282)Leach, IT, Symposium, "Identification of Drugs and Poisons," London, March 1965,Pharmaceutical Society of Great Britain, pp 57-iO; Anal. Abstr., 13, 3360 (1966). (1283) Leddicotte, G. Emery, J. F., Bate, L. C., U.S.,4t. Energy Comm. hecession KO. 43937,Repl. O R N L - T M 1263 (1965);Chem. Abstr., 65, 8673h (1966). (1284) Lederer, X.,llarini-Bettolo, R., Roch, G., Ric. Sci., 36 ( 3 ) ,193-5 (1966); Chem. Abstr., 65, 2064h (1966). 234 R


(1319)Linari, G., Marri, R., ibid., 105 (ll),853-4 (1966); Chem. Abstr., 66, 79655m (1967). (1320) Linek, K., Kuniak, L., Alince, B., Chem. Zvesti, 21 (1-2), 99-103 (1967); Chem. Abstr.. 67. 32895v 119671. (1967). (1321)Liptay,' G.,' Orban, E., Toth, G., Arch. Pharm. (M'einheim), 300 ( 8 ) , 660(l2s7) Lee, IF-.K., Yakhak Hoeji, 9 (1-2), 6 (1967);Chem. Abstr., 68,62299(1968). 4-7 (1965);Chem. Abstr., 65, 13457d (1322) Lisboa, B. P., Clin. Chim. Acta, 13 (1966). (2),179 (1966);Anal. Abstr., 13, 6433 (1288) Lefebvre, J. Ch., Labo-Pharma, 1 1 9 6 6 ) . 1966 (144),pp 56-65;Chem. Abstr., 65, (1323)Lisboa, B. P., J . Chromatogr., 19 l5151f(1966). (l), 81 (1965). (1289)Lehrfeld, J.,J . Chromatogr., 32 (41, (1324) Ibid. (2),p 333. 685-91 (1968). (1325) Lisboa, B. P.,J . Pharm. Belg., 20 (1290) Leifertova, I.,Brazdova, V., Cesk. (11-12), 435-49 (1965);Chem. Abstr., Farm., 16 ( i )352-4 , (1967); Chem. Abstr., 65, 570c (1966). 68, 6133w (1968). (1291) Lemli, J., Herba Hung., 5 (2-3j, (1326) Lisboa, B. P., Steroids, 6 ( 5 ) , 605 (1965). 198-204 (1966);Chem. Abstr., 68,532712 (1327) Ibid., 8 (3),319-44 (1966). 11968). (1328)Lobanov, V. I.,Zh. Anal. Khim., (1292)Lesigang-Buchtela, M.,Oesterr. 21 (12),1506-i (1966); Chem. Abstr., 66, Chemiker-Ztg., 67 (4), 115-21 (1966); 58870n (1967). Chem. Abstr., 65, 6269f (1966). (1329)Logar, S., Perpar, ll.,Farm. T7estnik (1293) Letiig, E.,Nahrung, 9 (3),357(Ljubljana), 18 (5-8), 116-32 (1867); 62 (1965j.; A n a l . Abstr., 13,3805 11966). Chenz. Abstr., 68, 62723a (1967). (1294)Levine, J., Doyle, T. D., J . Ass. (1330)Lokshin, G.B., Zhdanovich, Yu. O$c. Agr. Chem. 48 f3),608 (1965). V., Kuzovkov, A. D., Antibiotiki, 11 (1295)Levine, J., Doyle, T. D., J . Pharm. ( 7 ) , 590-4 (1966); Chem. Abstr., 65, Sci., 56 (5),619-22 (1967). 151639 (1966). (1296) Levine, J.,Hohmann, J. R., J . Ass. (1331) Longo, R., Fumagalli, U., Boll. OBc. Anal. Chem., 49 (3),533-6 (1966). Chim. Farm., 105 (lo),767-9 (1966); (1297) Levorato, C., Cima, L., J . ChroChem. Abstr., 66, 79640c,(1967). matogr, 32 (4),771-3 (1968). (1332)Longo, R.,Mazzoldi, G., abid. (3), (1298)Levorato, C., LIantovan, R., Boll. pp 241-4;Chem. Abstr., 65,2067e 11966). Chim. Farm., 105 ( 3 ) , 231-6 (1966); (1333) Loo, T. L., Dion, R. L., J . Pharm. Chem. Abstr., 55, 1387d (1966). Sci., 54, 809 (1965). (1299)Ibid. (6), pp 450-5; Chem. dbstr., (1334) Look, J. X, J . Ass. O#c. Anal. 65, 18430b (1966). Chem., 50 (3),664-6 (1967). (1300)Lewzndowska. I.. Soklowska. I., 1133j) Look. J.. J . Pharm. dci., 56 ill), Dass. Pharm. Pharmacol, 20 (I),81-6 1526-7 (1967). (1968);Chem. $bstr., 68, 814358 (1968). (1301)Lewandowaki, A,, Jarcxewski, -L, (1336)Lowenstein, J. AI., Corrill, E. hl., J . Lab. Clin. X e d . , 67 (6),1048 (1966). Chem.Anal. (Warsan-),11 (2),417(1966); (1337)Luckner, hl., Bessler, O., Luckner, Anal. Abstr., 14, 4080 (1967). R., Pharm. Zentralh. Deiit., 106 (4), 223(1302)Lhoste, J. AI., Tonnard, F., J . 39 (1967); Chem. Abstr., 67, 36377a Chim. Phys., 63 (5), 678-8G (1966); (1967). Chem. Abstr., 65, 13052e (1966). Freimuth, E.,Nahrung, (1303)Libanska. A., Cesk. Farm., 16 (4), (1338) Ludwig, E., 8 16-71. 563 11964): 198-200 '1967); Chem. Abstr., 67,67607e . , , Anal. Abstr., 12, 5481 (1965). (1967). (1339) Lugovoi, S. V., Ryazanov, I. P., (1304)Libby, D. A., Prosser, A. R., ShepZh. Anal. Khim., 22 ( 7 ) , 1093-7 (1967); pard, A . J., J . Ass OBc. Anal. Chem., 50 Chem. Abstr., 67, 111474k (1967). (4), 806-9 11967). (1340) Lukkari, I., Alha, A,, Ann. Med. (1303)Libicky, A,, Cesk. Farm., 16 ( 3 ) , E x p . Boil. Fenniae (Helsinki), 43 (3), 158-68 (1967);Chem. Abstr., 67, 67605~ 188 (196.5);Anal. Abstr., 14,1556 (1967). 119671 (1341)Lundgren, P., Acta Pharm. Suecica, (1366j Libinson, G. S.,Surkova, K. I., 3 (6), 397-404 (1966);Chem. Abstr., 67, -4ntibiOtiki, 12 (l),8-10 (1967);Chem. 5681r (1967). Absfr., 66, 6SSY2k (1967). (1342)Lundgren, P.,Strom, S., ibid. (4), (1307) Liesenklas, \T,, Auterhoff, H., Deut. pp 273-80; Chem. Abstr., 68, 6147d A.notheker-Zta.. 105 (37),1243 (1965); (1968). Anal. ASstr.,"14,373 (1967). (1343) Lundstrom, J., Agurell, S., J . Chro(1308)Lieu, V. T.?Diss. ilbstr., B, 27 (6), matoor.. 30 (11,271-2 (1967). 1966); Chem. Abstr., 66, 118883.f ; Univ. Microfilms (Ann Arbor, (1344)"Lushchevskaya, G.hl., Shmigidina, , Order Xo. 66-13,707, 103 pp. A. M., Aleleva, L. V., Farmatsiya (Moscow), 16 (l), 60-3 (1967);Chem. Abstr., (1309)Ligeti, G., Gyogyszereszet, 10 (6)) 208-11 11966);Chem. d b s t r . , 65, 14403b 66. 985357,(1967). 11966). (1345) Lutomski, J., B i d . Inst. Roslin (1310)Likhusherstov, L. l l . , Brossar, L. Leczniczych, 10 (2-3),71-98(1964);Chem. E., K h i m . Prir. Soedin., 3 (1)3 i-10 Sbstr.. 63. 4097e (1965). IlY671; Chem. Abstr., 66,12187Yq (1967). (1346)Lutomski, J., Herha Pol., 11 (3), (1311j Lin, Song-Ling, Diss. A&(.., B, 27 112-26 (1965);Chem. Absfr., 66, 795448 (9)>303'2 il9G7). (196i). (1312) Lin, Song-Ling, J . Phnrm. Sci., 56 (1347) Ibid., 12 (3),151-72 (1966);Chem. f9), 113U-4U (1967). Abstr., 67, 93943.f(1967). (1313)Liil, Song-Ling, Blake, 11.I., ibid., (1348)Ibid. (4),pp 227-42;Chem. Abstr., 55, is1 (196G). 67. 939440 (1967). (1314)Ibid. is),pp S61-6. (1345) Ibid, pp 243-59;Chem. Abstr., 67, (1315)Ibid., 56 (l),43-6 (1067). 93945h (1967). (1316) Lin, \-ali-Tang, Jt'any, Kung(1350j Lutomski, J., Xowalewski, Z . , Tsung, Yang, Tsai-I, Chemzstry (Taipei), Drost, K., Schmidt, IC., ibid., 13 (1-2), 1966 (1it pp 29-37; -Anal. Abstr., 14, 44-52 (1967);Chem. Abstr., 68, 6132v 4256 (1967,. (19681. (1317) Ibid. 12), pp 43-6; Anal. Abstr., 14, (1351)Lutomski, J., Kowalewski, Z., Kor5703 11967). tus, LI., Diss. Pharm. Pharmacol., 18 (1318)Linari, G.>Boll. Chini. Farm., 106 (4),409-14 (1966);Chem. Abstr., 66, (5), 307-8 (1967); Chern. Abstr., 67, 221700 1196;). 84938f (1 967).

(1285) Ledvina, M.,Baladova, D., Cesk. Farm., 14 (9), 457 (1965);Anal. Abstr., 14, 270 (1967). (1286)Lee, Lu-Hsien, Ou, Chia-Wei, Hhieh, Shu-Min, H u a Hsueh Hsueh Pao, 31 (6),482 (1965);Anal. Abstr., 14,2194

(1352) Zbid., 19 ( 5 ) , 551-6 (1967); Chem. Abstr., 68, 43142u (1968). (1353) L u t o m s k i , J., Raszejowa, W., Jastrzebska, hl., ibid. (4), pp 417-22; Chem. Abstr., 68, 33221e (1968). (1354) Lutomski, J., Szostak,H.,Speichert, H., Herba Pol., 12 (3), 200-7 (1966); Chem. Abstr., 67, 84911s (1967). (1355) Ma, Chine-Wen, Yao Hsueh Hsueh Pao, 13 (l),50-4 (1966); Chem. Abstr., 65, 5303d (1966). (1356) McCarthy, J. L., Brodsky, A. L., Mitchell, J. A., Herrscher, R. F., Anal. Biochem., 8 (2), 164 (1964). (1357) McCarthy, T. J., Price, C. H., Pharm. Weekblad, 100 (25), 761 (1965); Anal. Abstr., 13, 6478 (1966). (1358) McConnell Davis, T. W., J . Chromatogr., 29 ( l ) ,283-7 (1967). (1359) hlacek, K., Ann. Ist. Super Sanita, 2 (l), 133-49 (1966); Chem. Abstr., 66, 40732~’(1967). (1360) Macek, K., Vecerkova, J., Stanislova, J., Pharmazie, 20 (lo), 605 (1965); Anal. Abstr., 14, 965 (1967). (1361) McGilveray, I. J., Strickland, R. D., J . Pharm. Sci., 56 (l),77-9 (1967). (1362) Machek, G., Sci. Pharm., 34 (2), 122-7 (1966); Chem. Abstr., 65, 13455b (1966). (1363) Machek, G., Lorenz, F., ibid. (3), pp 213-31; Chem. Abstr., 66, 22258e (1967). (1364) Machovicova, F., Farm. Obzor, 35 (lo), 450-53 (1966); Chem. Abstr., 66 79634d (1967). (1365) NcKenna, J., Rippon, -4.E., Biochem. J., 95 ( l ) ,107 (1965). (1366) Mcllartin, C., Street, H. V., J . Chromatogr., 22 ( 2 ) , 274-85 (1966). (1367) Zbid., 23 (2), 232 (1966). (1368) Madrid, H. G., Rev. Real Acad. Cienc. Exact. Fis. N u t . Madrid, 59 (4), 623-9 (1965); Chem. Abstr., 65, 20689 (1966). (1369) Alaehr. H., Schaffner, C. P., J . Chromatogr., 30 ( 2 ) , 572-8 (1967). (1370) Maggiorelli, E., G. X e d . Mil., 117 ( l ) ,66-70 (1967); Anal. Abstr., 15, 2250 (196s). (1371) Maggiorelli, E., Gangemi, G., Boll. Chim. Farm., 105 (2), 128-30 (1966); Chem. Abstr., 65, 572h (1966). (1372) Maggiorelli, E . , Gangemi, G., and Conti, L., ibid. (12),pp 893-7; Chem. Abstr., 67, 14092r (1967). (1373) Mahn, F. P., Viswanathan, V., Senkowski, B. Z., J . Pharm. Sci., 57 (l),145-7 (1968). (1374) Majlat, P., Bayer, I., Acta Pharm. Hung., 37 (5), 204-8 (1967); Chem. Abstr.. 67. 111475m (1967). . , (1375) Ibid.; pp 209-4; Chem. Abstr., 67, 111476n (1967). (1376) Zbid. (6), pp 243-6; Chem. Abstr., 68, 16177c (1968). (1377) Majumdar, SI. K., Majumdar, S. K.. AXAL.CHEM.. 39. 215 11967). (13i8) Makino, T., Kazama, A., Ueda, F., Bztamin, 35 (2), 128-35 (1967); Chem. Abstr., 66, 79637g (1967). (1379) M a k i n o , T . , Y a m a s h i t a , O., Kazama, A., Ueda, F., ibid., 37 ( 2 ) , 13542 (1968); Chem. Abstr., 68, 62746k (1968). (1380) Llalejka, D . , P o z n a n . T o w a r z . Przyjaciol N a u k , Wydzial Lekar., Prace Komisji Farm., 4, 73-82 (1966); Chem. .4bstr., 65, l5155e (1966). (1381) Malysz, D., Nowakoaska, Z., Acta Polon. Pharm., 23 ( l ) ,39-45 (1966); Chem. Abstr., 65. 2066d (1966). (1382) Mslgsz, D.,‘Perkowski, E., Turska, IT., TTalicka, T., ibid., 24 (3), 307-13 (1967); Chem. Abstr., 68, 62730a (1968). (1383) Mancini, B., Tribuna Farm., 34 (3-4), 113-16 (1966); Chem. Abstr., 68, 16186e (1968).

(1354) Manikowski, W., Niezgodzki, L., Farm. Polska, 21 (17-18), 657-8 (1965); Chem. Abstr., 65,. 2067e (1966). (1385) Manikowski, W., Niezgodzki, L., Poznan. Towarz. Przyjaciol N a u k , W y d zial Lekar., Prace Komisji Farm., 4,15964 (1966); Chem. Abstr., 65, 15159c (1966). (1356) Ibid., pp 165-8; Chem. Abstr., 65, 15159h (1966). (1387) RIarais, J. P., J . Chromatogr., 27 (l), 321-3 (1967). (1388) Marciszewski, H., Spychala, S., Acta Polon. Pharm., 24 (l),37 (1967); Anal. Abstr., 15, 2245 (1968). (1389) Marciszewski, H., Trojanowska, Z., Pogorzelska, J., ibid. ( 2 ) , pp 155-9; Chem. Abstr., 67, 1028549 (1967). (1390) Marcucci, F., Mussini, E., J . Chronzatogr., 18 (a), 431 (1965). (1391) hllarczal, G., Kolos-Pethes, E., Gyogyszereszet, 11 (5), 179-83 (1967) ; Chem. Abstr., 68, 6223a (1968). (1392) Mares, V., Stejskal, Z., Cesk. Farm., 16 (9), 474-9 (1967); Chem. Abstr., 68, 81465j (1968). (1393) Margasinski, Z., Danielak, R., Rafloaska, H., Acta Polon. Pharm., 23 (l), 35-7 (1966); Chem. Abstr., 65, 2066a (1966). (1394) Margasinski, Z., Danielak, R., Rafalowska, H., Nowakowska, Z., ibid., 24 (3), 301-5 (1967); Chem. Abstr., 68, 627299 (1968). (1395) Mariani, A., hlariani-Vicari, C., Mendoza, R., Ann. Ist. Super. Sanita, 2 15), 542-4 (1966); Chem. Abstr., 66, 79525u 11967). (1396) hlariani, A., Mariani-Vicari, C., Mendoza, R., Cisbani, B., ibid., 3 ( 2 ) , 193-203 (1967);Chem Abstr., 67,111486r (1967). (1397) llarinescu, I., Rezei, C., Florean, E., Pharmazie, 21 (12), 756 (1966); Chem. Abstr.. 66. 108302b 11967). (1398) Marini-Bettblo, G. B., Monache, F. D., Brovetto, A . G. de, Corio, E., J . Ass. Ofic. Anal. Chem., 51 (l),185-91 (1968). (1399) Marini-Scotti, M.,Boll. C h i m . Farm.. 104 16). 356 (1965): Anal. Abstr.. 13, 5783 (1966). (1400) hlarkacheva, T. %I.,Iiornilova, L. I., K h i m . Produkty Koksovaniya Uglei Vostoka SSSR, Poluchenie, Obrabotka, Ispol’z., Metody Analizov, Vost. Nauchn.Issled. Uglekhim. Znst., Sb. Statei, 3, 3204 (1965); Chem. Abstr., 65, 10c (1966). 11401) Markovic. Ll.. Arhiv Farm. (Belgrade), 15 (2); 139-46 (1965); Chem. Abstr., 66, 58856n (1967). (1402) Markovic, >I., Blagojevic, Z., ibid., 16 (l), 5-11 (1966); Chem. Abstr., 66, 79661k (1967). (1403) Maroszynska, K., Lipiec, T., Chem. Anal. (Warsaw). 11 13). 515 11966): Anal. Abstr.. 14.’ 5705‘t1967). (1404) Marques deSa, L., Rev. Fac. Farm. Bioquim. Univ. S u o Paulo, 5 ( l ) ,231-5 (1967); C h e m Abstr., 68, 16187j (1968). (1405) llartella, F., Farmacista, 22 (3), 49-53 (1967); Chem. Abstr., 67, 67532b

,.

( 1 467) ,*””.

(1406) Martelli, A., Nano, G. hl., Farmaco, Ed. Prat., 22 (l),660-5 (1967); Chem. Abstr.. 68. ~-~ 1 6 1 7- 0 ~il96R). (1407) ilarten, J. F., Technicon Symp., 2nd Ar. Y . London, 1965, 50-3 (Pub. 1966); Chem. Abstr., 67, 57247y (1967). (1408) Martin, G. E., Swinehart, J. S.. ANAL.CHEW,38 (12), 1789-90 (1966): (1409) lfartin, R. J., Alexander, T. G., J . A s s . O i c . A n a l Chem., 50 (6), 1362-6 (1967). (1410) Zbid., 5 1 ( l ) , 159-63 (1968). (1411) hfaruchin, J. E., Farm. Polska, 22 (3), 177-80 (1966); Chem. Abstr., 65, 10424~ i~ ~ . - i-f i ) . (1412) Mary, N. Y., J . Pharm. Sci., 56 (12), 1670-2 (1967). I

2

\ - - - - ,

\ - - - -

(1413) Masterson, D. S.,ibid., 57 (a),3058 (1968). (1414) Mathieson, A . McL., Perspect. Struct. Chem., 1, 41-108 (1967); Chem. Abstr., 68 21327f (1968). (1415) Mathis, C., Kaess, A., J . Pharm. Belg., 21 (11-12), 561-6 (1966); Chem. Abstr., 66, 79613w (1967). (1416) Matlina, E. Sh., T r . Novoi A p parature Metodikam, Pervoi Mosk. Med. Znst., 1965 (3), pp 84-87; Referat. Zh., Biol. K h i m . 30F, 1966 (3), Abstr. No. 3F108; A n a l Abstr., 13, 5045 (1966). (1417) Matlina, E. Sh., Kiseleva, Z. &I., Probl. Endokrinol. i Gormonoterap., 12 ( 2 ) , 111 (1966); Anal. Abstr., 14, 6324 (1967). (1418) hlatlina, E. Sh., Kiseleva, Z. AI., Sofieva, I. E., Tr. Novoi Apparature Metodikam, Pervoi Mosk. Med. Znst., 1965 (3), pp 25-32; Referat. Zh., Biol. K h i m . 30F, 1966 (3), Abstr. No. 3Fl50; Anal. Abstr., 13, 5046 (1966). (1419) Matlina, E. Sh., Sofieva, I. E., Kiseleva, Z. hl., ibid., pp 15-24; Rejerat. Zh., Biol. K h i m . 30F 1966 (9), Abstr. No. 9F78 Anal. Abstr., 13, 6395 (1966). (1420) N a t o l c s y , E . Z., A c t a P h a r m . Hung., 37 (4), 167-72 (1967); Chem. Abstr., 67 102849j (1967). (1421) Matos, F. J. A . , Sousa, 11. P., Barros, 31. M., Lima, 31. E., Sascimento, M. C., Rev. Brasil. Farm., 47 (6), 331-41 (1966); Chem. Abstr., 67, 57268f (1967). 11422) XIatrka, ?*I., Spevak, A,, Chem. Listu. 61 (7). 883-96 (1967): Chem.

84; 20-2 (1966); Chem. Abstr., 37, 25431n (1967). (1425) M a t s u m o t o , H . , A r c h . P r a c t . Pharm., 24 (4), 304 (1965); Anal. Abstr., 13, 7093 (1966). (1426) Matsumoto, H., Yakuzaigaku, 25 (4). 62-4 (1965):Chem. Abstr., 65.184280 (1966). (1427) hlatta. G.. Silva. 11. J.. Rev. Port. Farm., 16 ’(4),’ 407-i6 (1966); Chem. Abstr., 66, 9846824 (1967). (1428) Mattocks, A. R., ANAL.CHEW,39 (4), 443-7 (1967). (1429) Mattocks, A. R., J . Chromatogr., 27 (2). 505-8 11967). (1430) Matucha, JX.!Svoboda, V., 2. Anal. Chem., 220 (4), 279 (1966); Anal. Abstr., 14, 7123 (1967). (1431) Matveja, M.,Gofman, B. E., Shimanskaya, SI.V., Konstante, G., Piperazin, Akad. N a u k Latv. SSR, Znst. Ora. Sin.; 1965, pp 116-23; Chem.’Abstr., 66, 43536; (1967). (1432) IIatz, A. R., Bull. Parenteral Drug Ass., 20 (4),130-5 (1966); Chem. Abstr., 66, 222941, (1967). (1433) LIauer, P., Mikrochim. Acta, 1966 (6), 965-9; Chem. Abstr., 66, 40753s (1967). (1434) May, J. R., Zvirblis, P., Kondritzer, A. A , , J . Pharm. Sci., 54,1508 (1965). (1435) llaycock, W. d’A.; Ricketts, C. R., Nature, 213 (5071), 88 (1967). 11436) Mavr. E.. Knv. L.. Richter. J.. Arzneim&lstandard&erung, 6, 509-11 (1965); Chem. Abstr., 66, 22225s (1967). (1437) Zbid.. DD 512-14: Chem. Abstr.., 66., i 4 o m (iG67j. (1438) llazor, L., Balla, J., Bekassy, S., Takacs, J., 2. Anal. Chem., 218 (4), 272 (1966); Anal. Abstr., 14, 4972 (1967). (1439) lfazur, X. >I., Devyatnin, V. A., Med. Prom. SSSR, 20 (6), 50-3 (1966); Chem. Abstr., 65, 13455d (1966). (1440) hledvedovs’kii, A. O., Farm. Z h . (Kiev), 22 (6), 18-21 (1967); Chem. Abstr., 68, 53297n (1968). (1441) Meier, J., Buechler, W.,Arch. VOL. 41, NO. 5, APRIL 1969

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Pharm. (Weinheim), 300 (9), 811-15 (1967); Chem. Abstr., 68, 245852 (1968). (1442) Menn, J. J., AlcBain, J. B., Nature (London), 209, 1351 (1966). (1443) Menon, P. S., Kulkarni, V. S., Indian J . Technol., 5 (5), 168-9 (1967); Chem. Abstr., 67, 676449 (1967). (1444) llenssen, H. G., Honerlagen, H., Mitt. Deut. Pharm. Ges., 34 (6), 97 (1964); Anal. Abstr., 12, 5403 (1965). (1445) Mesley, R. J., Spectrochim. Acta, 22 ( 5 ) , 889-917 (1966); Chem. Abstr., 65, 1594h (1966). (1446) Mesley, R. J., Houghton, E. E., J . Pharm. Pharmacol., 19 ( 5 ) , 295-304 (1967). 11447) Meslev. R. J.. Johnson. C A , . ibid..

(1470) Milch, G., Gyorbiro, K., Bittera, B., Proc. Con$ Appl. Phys.-Chem. Methods Chem. Anal., Budapest, 1966, 1,20610; Chem. Abstr., 68, 53286h (1968). (1471) Milch, G., Hollos, J., Aczel, K., Bittera, K., Pharm. Zentralh. Deut., 104 ( 8 ) , 564 (1965); Anal. Abstr., 13, 7096 (1966). (1472) Milch, G., Holly, S., Csontos, A., Borsai, M., Proc. Conf. Appl. Phys.Chem. Methods Chem. Anal., Budapest, 1966,3,97-103; Chem. Abstr., 68,33222f (1968). (1473) Mills, G. C., Texas Rept. Bid. Med., 23 (4), 756 (1965); Anal. Abstr., 14, 888 (1967). (1474) Minutilli, F., Rass. Chim.,18 (3), 121-4 (1966); Chem. Abstr., 66, 6896% (1967).

(Athens), 22 (566,’ 118877g (ig6f). (1450) Jlesnard, P., Pharm. Dellion Epistemonika E k d o s i s , 6 (3-4), 114-38 (1966);Chem. Abstr., 67, 25416m (1967). (1451) Xesnard, P., Devaux, G., Bull. Trat‘. SOC.Pharm. Lyon, 9 ( 3 ) , 120-8 (1965); Chem. Abstr., 65, 16793d (1966). (1452) llesnard, P., Devaus, G., Bertucat, M., Bull. SOC.Pharm. Bordeaux, 104 ( 3 ) , 145-51 11965): Chem. Absir., 65, 2068e (1966). (1453) 11ess er s c h mid t , LI-., A rzn eim . Forsch., 15 i l l ) , 1339 (1965);9nal,Abstr., 14, 1654 (1967). (1454) Messerschmidt, IT., Peter, H., ibid., 16 13), 440-3 (1966); Anal Abstr., 14, 4236 11967). (1455) lletcalf, 11.G., Anal. Biochem., 13 13), 483 (1965). (1456) lIeunier, J., Yiozssat, B., Leterrier, F., Douzon, P., ‘4nn. Pharm. Fr., 25 ( l l ) ,683-96 (1967); Chem. Abstr., 68, 532780 (1968). (1457) llever. R.. Rollet. 11.. Kirk-Othmer -Encycl. Cheni. Technol.: Pnd‘d., 3, 6077 (1964);Chem. Abstr., 65, 569b (1966). (1458) S l e y t h a l e r , C . , D w o r a k , G . , Schmid, E., Arzneim.-Forsch., 16 (7), 800 (1966);Anal. Abstr., 14,6992 (1967). 11459) Nezentsev. A. S.. Krunlvak. E. B.. Tyutyukova, i’: A., Brazl%kova, M: G., Dokl. Akad. S a u k SSSR, 168 (l), 207-10 (1966); Chem. Abstr., 65, 15156h (1966). (1460) Michalska, B., Zurkowska, J., Ozaromki, A,, Acta Polon. Pharm., 23 f4), 325-329 (1966); Anal. Abstr., 14, 6373 11967). (1461) hlichaud, J., Ann. Pharm. Fr., 24 (7-8), 533 (1066); Anal. Abstr., 14, 6375 (1967). (1462) Xichaud, J., B i d . SOC. Pharm. Bordeaux, 105 14), 219-24 (1966); Chem. Abstr., 67, 5721d (1967). (1463) Mikolaiek. -4.. Acta Polon. Pharm.. 24 ( 3 ) , 3 3 7 4 (1967); Chem. Abstr., 68; 7 3 2 8 9 ~(1968). (1464) Nikolaiek. E.. Kormicki. J.. Kowalczyk, Z., Diss. Pharm. Pharmawl., 18 i s ) , 223-8 ‘1966); Chem. Abstr., 67, 14905u (1967). (1465) llilch, G., Rorsia, l l , , Csontos, -4., Mogacs, I., Acta. Pharm. Hung., 36 (6), 246-52 (1966); Chem. Abstr 66, 2 2 2 4 1 ~ (1967). (1466) llilch, G , Borsai, ll., Mogacs, I., zbid., 37 111, 6-13 11967); Chem. Abstr., 66, 689982 (1967). (1467) llilch, G., Borsai, XI., Mogacs, I., Gyogyszereszet, 10 (101, 381-3 (1966); Chem. Abstr., 66, 58860~(1967) (1468) Ibzd., 11 (4), 149-51 (1967); Chem. Abstr., 67, 676672 (1967). (1469) Milch, G., Csontos, A , , Borsai, If., Vadon, E., Xogacs, I., Acta Pharm. H7tng., 36 ( 5 ) , 200-6 (1966); Chem. Abstr., 65, 18427h (1966). ~

236 R


(1475j Ibid. ( 5 ) ,pp 228-30; Chem. Abstr., 66, 118876f (1967). (1476) hlirescu, Rl., Rfonchiu, D., Popescu, T., Farmacia (Bucharest), 14 (lo), 61114 (1966);Chem.Abstr., 66,31993t (1967). (1477) Ibid., 15 (6), 373-6 11967); C h m . Abstr., 67, 84943d (1967). (1478) Misantone, R., Corriere Farm., 21 (17), 400-1 (1966); Chem. Abstr., 67, 102853f (1967). (1479) ?lisawa, T., Honma, S., Kaneshima, H., Kitayama, hl., Hokkaido-ritsu Eisei Kenkyushoho, 16, 97-100 (1966); Chem. Abstr., 65, 199349 (1966). (1480) hIitta, A . E. A., Camin, L. L., Troparevsky, M. L. P. de, Radiochim. Acta, 6 (a), 111 (1966); Anal. Abstr., 14, 7831 (1967). (1481) Mod, L., Acta Pharm. Hung., 37 13). 116-21 (1967): Chem. Abstr.. 67. , 254380 11967). 482) llodrzejewski, F., Farm. Polska, 23 ( 3 ) , 201-10 (1967); Chem. Abstr., 68, 6 2 6 1 7 ~(1968). 483) Modrzejewski, F., Kaczmarczyk, B., ibid., 20 (23-24), 879-83 (1964); Chem. Abstr., 63, 5455f (1965). 484) Moehrle, H., Deut. Apotheker-Ztg., 107 (23), 781-3 (1967); Chem. Abstr., 67, 84914~(1967). 485) llohay, J., Mohay-Farkas, J., Acta Pharm. Hung., 37 (2), 71-3 (1967); Chem. Abstr., 66, 9 8 5 5 6 ~(1967). 486) Llonciu. D.. Boteanu. S.. Vevera. C., Farmacid (Bucharest), 15 (3), 175-8 (1967); Chem. Abstr., 67, 84921~(1967). (1487) Ibid., (9), pp 533-7; Chem. Abstr., 67, 111380b (1967). (1488) Monder, C., Endocrinology, 82 (2), 318-26 (1968). (1489) llonnier, D., Martin, E., Haerdi, W., Anal. Chim. Acta. 34 13). 346 11966): An&. Abstr., 14, 3967 (1967). (1490) Monnier, D., Saba, R., Pharm. Acta Helv., 42 (6), 328-34 (1967); Chem. Abstr., 67, 67646s (1967). (1491) blontalvo, R., Wheeler, 0. H., Can. J . Chem., 44 (1)) 100 (1966). (1492) hlontgomery, K. O., Jennings, P. V.. Weinswin. 31.H.. J . Pharm. Sa.. 56 ,

I

I

,

~

(5). 49-55 (1966); Chem. Abstr., 66. 14d53u (1967). .496) Moraes. E. de C. F.. Rieser. D. S. A.,‘Sznelwar, R. B., Rev. Fac.’Farm. Bioquim. Univ. Suo Paulo, 3 (2), 369-79 (1965); Anal. Abstr., 14, 3388 (1967). ,497) Morait, G. Barza, P., Turculet, V., Farmacia (Bucharest), 15 (lo), 627-30 (1967); Chem. Abstr., 68, 33225j (1968). .498) Morait, G., Coada, M.,Petroniu, L., ibid. ( 3 ) ,pp 155-62; Chem. Abstr., 67, 14911t (1967). ,499) Moratello, R., Corriere Farm., 20 (l-3)> 272-4 (1965); Chem. Abstr., 65, lalo7f (1966).

(1500) Morrison, J. C., Chatten, L. G., J . Pharm. Pharmacol., 17,655 (1965). (1501) Morrison, J. C., Orr, J. M., J . Pharm. Sci., 55 (9), 936-41 (1966). (1502) Morvay, J., Stajer, G., Acta. Pharm Hung., 35 ( 5 ) , 199 (1965); Anal. Abstr., 14, 357 (1967). (1503) Moskalenko, R. I., Savel’eva, G. I., Farm. Zh. (Kiev), 22 (2), 24-8 (1967); Chem. Abstr., 67, 572852 (1967). (1504) Moss, 31. S , Rylance, H. J., J . Pharm. Pharmacol., 18 (l), 13 (1966). (1505) Moy, T. W.,JTetherell, H. R., J . ForenszcScz., 12 (2), 241-5 (1967);Chem. Abstr., 67, 102841~(1967). (1506) Moza, P. N., Khajuria, G. S., J . Chromatogr., 24 (l),261-2 (1966). (1507) S l u e h l e m a n n , H., T a t r a i , O . , Pharni. Acta Helc., 42 (12), 717-33 (1967); Chem. Abstr., 68, 2458ib (1968). (1508) llueller, K., ibzd., 43 (2), 107-22 (1968); Chem. Abstr., 68, 53312p (1968). (1509) Mueller, K. H., Braxl, C., Arch. Pharm., 299 (6), 560-2 11966); Chem. Abstr.. 65. 8675h 11966). (1510) jlu~ller-Mulot,I?., Fresenius’ Z. Anal. Chem., 226 ( 3 ) , 266-72 (1967); Chem. Abstr., 66, 1 0 1 4 5 6 ~(1967). (1511) Ibid., pp 272-9; Chem. Abstr., 66, 1 2 1 9 0 6 ~(1g67). (1512) Mulder. F. J.. Kuenine. IC ,I.. Anales Farm. Hosp., 10 (2@, 77-96 (1967); Chem. Abstr., 67, 67645r (1967). (1513) Xuller, E., Chem. Tech. (Berlin), 18, 630 (1966); Anal. Abstr., 15. 1034 (1968). (1514) Muratova, F. S.,Gengrinovich, A. I., Tr. Tashkentsk Farmatsvet. Inst., 4, 259-62 (1966); Chem. Abstr., 67,25430m f 19671. (isis) AIurav’ev, I. A., Ponomarev, V. D., V o p , Izuch. Ispol’z. Solodki SSSR, 1966, 133-44; Chem. Abstr., 67,111493r (1967). (1516) Murav’eva, D. A,,’ Savchenko, Y. A., F’ergeichik, E. T i . , Khim.-Farm. Zh., 1 ( l o ) , 56-8 (1967), Chem. Abstr., 68, 24572 (1968). (1517) Alurea, L , Madgearu, II., Cuciureanu, E., Beral, H., Rev. Chim. (Bucharest), 17 16)) 372-3 (1966); Chem. Abstr., 65, 18928e (1966). (1518) Murphy, B. P., J . Lab. Clin. N e d . , 66, ( l ) , 161 11965). (1519) llurrav, T. K., Day, K. C., Kodicek, E., Biochem-. J . , 98 ( l ) ,293 (1966). (1520) Murtazaev, A. AI., Avakyants, S. G., Tolok, P. P., Tr. Tashkentsk Farmatsevt. Inst., 4, 361-4 (1966);Chem. Abstr., 67, 254199 (1967). (1521) Nurtazaev, A . AI., Bazarbaev, A. T., Khabibullina. 2. T., zbid., pp 365-8; Chem. Abstr., 67, 676742 (1967). (1522) Murthy, K. S., Ripple, E. G., J . Pharnz. Sci.. 56 ( 8 ) . 1026-i (1967). (1523) Mustafaeva, L. I., Dzottsoti, S.K., Azerb. Med. Zh., 43 ( 8 ) , 72-5 (1966); Chem. Abstr.. 66. 222950 (1967). (1524) llustafaeva, L. I., Dzottsoti, S.K., L’ch. Zap. Azerb. Med. Inst., 22, 147-51 (1966): Chem. Abstr., 68. 332582 11968). (1525) hIuszalska, A,, Marciszewski, H., Chem. Anal. (Warsarv), 11 ( 3 ) ) 585 (1966); Anal. Abstr., 14, 5455 (1967). (1526) M y s z k o w s k a , K . , T a u t t , J . , Tuszynska, S., Acta Polon. Pharm., 24 (3) 325-30 (1967); Chem. Abstr., 68, 62741e (1968). (1527) Nadtoka, V. L., U.S.S.R. patent 192,360 (C1. A 61k) (Feb 6,1967); Appl. Aug 7 , 1964; Chem. Abstr., 68, 6276313 (1968). (1528) Nagahama, N., Suzuki, AI., Awataguchi, S., Okuda, T., J . Antibiot. (Tokyo), Ser. A , 20 (5), 261-6 (1967); Chem. Abstr.. 68. 1610% 11968). (1529) Nagfe, A . lI,,Radionovskaya, E. I., Trakhtenberg, D. hl., Kleiner, G. I., -4ntibiotiki, 12 ( 5 ) , 420-5 (1967); Chem. Abstr., 67, 762531, (1967). 1

~

.

(1530) Nagy, L. G., Nester, Z., Takacs, G., Magy. Kem. Foly., 73, 137-8 (1967); Chem. Ahstr., 67, 5720c (1967). (1531) Nair, P. P., Bucana, C., de Leon, S., Turner, D. A., ANAL.CHEM.37, 631 (1965). (1532) Tair, P. P., Sarlos, I., hlachiz, J., Arch. Bzochem. Biophys., 114 (3), 488 11966); Anal. Ahstr., 14, 4981 (1967). (1533) Sakagawa, K., McKiven, N. L., Forchielli, E., Vermeulen, A., Dorfman, R. I., Steroids, 7 (4),329-40 (1966). (1534) Nakamura, G. R., J . Ass. Ofic. Anal. Chem., 49 (5), 1086-90 (1966). (15.35) N a k a m u r a , II., Semonsky ?I., Ann, Pharm. Fr., 25 (3), 177-80 (1687); Chem. Ahstr., 67, 4 7 1 0 7 ~ (1967).

(166lj Parker, E. A., Amer. J . Hosp. Pharm., 24 (8), 434-49 (1967). (1662) Parrak, V., Radejova, E., Cesk. Farm., 16 (9), 447-50 (1967): Chem. Ahstr., 68, 72272s (1968). 11663) Parrak. V.. Ruzickova. J.. Antolik. P., Farm. Obzor,’34 ( 2 ) ,49 (1965); Anal: Ahstr., 13, 5141 (1966). (1664) Parrak, V., Ruzickova, J. Antolik, P., Pharmazie, 21 ( 7 ) , 418-24 (1966); Chem. Ahstr., 65, 18427f (1966). (1665) Parrish, D. B., J . Ass. O ~ CAnal. . C‘hem.. 49 15). 1066-1071 11966). (1666) Pasarib;, S , Suara Pharm., 10 (l), 9-12 (196i); Chem. Abstr., 67, 120226h il4671 ,- . ,. (1667) Pasaribu, S., Poey, S. B., ihid., 9 (j), 130-5(1966);Chem.Ahstr., 67,940432 (196:). (1668) Pasich, B., Adamczewski, B., Wisniewski, J., Farm. Polska, 22 (1-2), 35-41 (1966); Chem. Ahstr., 65, 12061a (1966). (1669) Pasich, J., Acta Polon. Pharm., 23 (3). 243-6 (1966): Chem. Ahstr., 65, 16i93a (1966). (1670) Pasich. J.. Pilawska. E.. Farm. Pnlfikn. 23 ‘ (2): 105-8 11967); Chem. ....... Ahstr.,’67,- 57271h-(1967): (1671) Passannante, A. J., Avioli, L. V., Anal. Biochem., 15 (2) 287 (1966). 11672) Pastor. J.. Bull. Soc. Pharm. Marseille, 14 (56), 245-65 (1965); Chem. Ahstr., 65, 3672d (1966). (1673) Pastor, J., Valimamod, V., Bull. Trav. SOC.Pharm. Lyon, 9 (3), 312-24 (1965); Chem. Ahstr., 65, 16791h (1966). (1674) Patriarche, G., J . Pharm. Belg., 20 (9-10), 336-42 (1965); Anal. Ahstr., 14, 111 (1967). (1675) Patriarche, G. J., Lingane, J. J., Anal. Chim. Acta, 37 (4),455-9 (1967); Chem. Ahstr., 66, 101450q (1967). (1676) Patn-a, N. T., Huyck, C. L., J . Amer. Pharm. Ass., 6 ( 7 ) , 372-3 (1966). (167T) Patzwaldt, H. G., Pharmazie, 21 (S),468 (1966); Anal. Ahstr., 14, 7796 (1967). (1678) Pawelczak, >I., Acta Polon. Pharm., 24 (6), 615-18 (1967); C’hem. Ahstr., 68, 62761m fl968’1. (1679) Zhid., pp 661-2; Chem. Ahstr., 68, 62721y (1968). (1680) Pawelczyk, E., Domeracki, S., Diss.Pharm. Pharmacol., 18 (6), 651-8 (1966); Chem. Ahstr., 67, 25443t (1967). (1681) Pawelczyk, E., Hermann, T., a s s . Pharm., 17 (4), 569-75 (1966); Chem. dhstr., 65, 2313h (1966). (1682) Pawelczyk, E., Malejka, D., Farm. Polska, 23 ( l ) , 39-47 (1967); Chem. Ahstr., 67, 76331n (1967). \ -

-

I

\ -

,

/

632 (1964). (1697) Pekel, N. D., Berezovskii, V. hl., Med. SSSR, 20 ( l l1) ,,21-3 (1966); Chnm,Prom. Abstr.., zz < * ,nom\ 00, llaabla (130,). J. R., bIetcalfe, L. D., ANAL. n n O l

6 1 9 8 ~(1968). (1700) Pellerin, F., Prod. Prohl. Pharm., 22 ( l ) ,16-28 (1967); Chem. Abstr., 66,

cw,mn ii -----n \ - 967). --.

(1701) Pellerin,’ F., Demay, D., Mancheron, D., Ann. Pharm. Fr., 25 (9-10), 613-19 (1967): Chem. Ahstr., 68, 53283e (1968). (1702) Zhid., 25 ( l l ) , pp 757-60; Chem. Abstr., 68, 53313q (1968). (1703) Pellerin, F., Gautier, J. 4., Demay, D., shid., 24 ( l l ) , 675 (1966); Anal. Ahstr.. 15. 981 (1968). (1704) Pelt,’ J. &I.,Junk, M.G., Younos, I f . C., Plant Med. Phytother., 1 (2-3), 118-29 (1967); Chem. Ahstr., 67,111471g (1967). (1705) Perego, R., Castoldi, B., Farmaco, Ed. Prat., 23 (2), 98-101 (1968); Chem. Ahstr.. 68. 72290w (1968). (1706) Perego, R., Sekules, G., Boll. Chim. Farm., 106 ( l ) , 31-7 (1967); Chem. Abstr., 67, 5714d (1967). (1707) Perego, R., Sekules, G., Guadagnini, G., Farmaco, Ed. Prat., 22 (3), 15966 (1967); Chem. Abstr., 67, 5677u (1967). (1708) Perlia, X., Pharm. Acta. Helu., 42 ( 5 ) , 265-302 (1967); Chem. Ahstr., 67, 25381w (1967). (1709) Pesez, hl., Bartos, J., Ann. Pharm. Fr., 23 (4), 281 (1965); Anal. Ahstr., 13, 4181 (1966). (1710) Zbid., 23 (12), pp 781-2; Chem. Abstr., 65, 3003d (1966).

(1711) Ibid., pp 783-4; Chem. Abstr., 65, 5729 (1966). (1712) Peter< J. H., Miller, K. S., Brown, P., Anal. ilochem., 12 ( 2 ) , 379 (1965). (1713) Petkovic, LI., Arhiv. Farm. (Belgrade), 15 (6), 437-8 (1965); Chem. .4bstr., 66, 319SOm (1967). (1714) Zbid., 16 ( l ) , 19-22 (1966); Chem. Abstr., 66, 689870 (1967). (1715) Ibid., 17 (21, 77-9 (1967); Chem. Abstr., 68, 8 9 8 8 7 ~(1968). (1716) Petkovic, LI., Farm. Glasnik, 22 (6), 229-31 (1066); Chem. Abstr., 65, 15155h (1966). (1717) Zbid., 23 (lo),445-8 11967); Chern. d b s t r . , 68, 8 1 4 3 6 ~‘1968). (1718) Petrangeli, B., Boll. Chim. Farm., 105, 770-2 11966); Chem. Abstr., 66, 40748u (1967). (1719) Ibid., 106, (91, 629-32 11967); Chem. Abstr.. 68. 1 6 1 8 2 ~11968). (1720) Zbid., pp 653-6; Chdm. Abstr., 68, 16183b (1968). (1721) Petricir, J., Petricic, V., BarisicPoljak, I., Acta Pharm. J.ugoslao., 17 (I), 29-34 (1967); Chem. Bbstr., 67, 57272~(1967). (1722) Petropavlovskii, E. I.. Ustinova, -4.V., Zzv. V-ysshikh Cchebn. Zavedenii Pishchevaya Tekhnol., 1967 (6), 36-9; Chem. Abstr., 68, 72241s (1968). (1723) Pflegel, P., Pharm. Zenfralh. Deut., 106 ( 8 ) , 509-17 (1967); Chem. Abstr., 67, l l l 5 l l v (1967). (1724) Pflegel, P., Kagner, G., Pharmazie, 22 (31,147-53 (1967); Chcni. Abstr., 67, 1WS:jOc 11CJ67). (1725) Pfeifer, S.,J . Chromatogr., 24 (21, 364 (1966). (1726) Pfeifer, S., Pharm. Ztg., 1 1 1 (13), 463-8 (1966): Chcm. Abstr., 65. 2313c (1966). 11i2i) Pfeifer. S.. Thomas. D.. Pharmazie. 22 ’(,Sjj 454 (1967); Chem.’ iibstr., 68; 6130t (1968). (1728) Phillips, B. lI.] Kraus, P. J., Stratmeyer, 11. E., J . Pharm. Sci., 54, 803 (1965). (1729) Phillipson, %J.D., Shellard, E. J., J . Chromatoor.. 24 11) 84 (19661. (1730) Piechoiki, J.,’ koczniki panstwowego Zakladu Hig., 17 (6), 529-33 (1966); Chem. iibstr., 66, 72241q (1967). (1731) Piechocki, J. T., J . Pharm. Sci., 57 ( I ) , 134-6 11968,. (1732) Pietramaggiori, F., Fitoterapia, 36 ( I ) ,2-7 (1965); Chem. Abstr., 65, 2313c (1966). (1733) Pijek, J., Claeys, A., J . Pharm. Belg., 21 19-101, 477-84 11966); Chem. Abstr., 66, 68968q (1967). (1734) Pilipenko, A. T., Kladnitskaya, 11. B., Zavod. Lab., 32 ( I ) , 3 (1966); 4 n a l . Abstr., 14, 2399 (1967). (l73,5) Pillion, E., Rogers, 11.R., Kaplan, 4. 11..Soaz, Chem. Swecialties. 42 1 5 ) . 90, 94: 99-io0 11966): Chem. Abtr., 65; 53050 (1966). (1736) Pillsbnry, H. C., Sheppard, A. J., Libby, D. A., J . Ass. Ofic. S n a l . Chem., 50 141, 809-14 (1!367). (1737) Pilsbury, V. B., Jackso:, J. V., J . Pharm. Phurwzacol.. 18 (11). (13 (1966). 11738) Pinyazhko, R’. AI., -4ptechn. Delo, 15 ( G ) , 42-6 (1966,; Chem. d b s t r . , 66, 79627d (1967). (1739) Piiigszhku, R . >I., F a r m . Z h . (Kiev), 21 15) 14-16 (1966); Chem. Abstr., 66, 407& (1967 #. (1740) Ibid.; 21 16), pp 20-1; Chem. Abstr., 66, OS543q (1967).

(1741) Pitel, G., LIICC,T., 9nn. Pharm. Fr.. 23 i l l ) . 673 11965):Anal..4bstr.. , 14., 15g5 (1967~i. (1742) Petet, G., M i s r s Point Chim. Anal. Org. Pharm. BrOmatOl., 16,133-69 (1967); Chem. Abstr., 68, 431921; 11968). (1743) Pitton, J. S., Antibiot., Advan. Res., Prod. Clin. Cse, Proc. Congr., Prague,

1964, pp 49@-5 (Pub. 1965); Chem. Abstr., 66, 407431, (1967). (1744) Pitton, J. S., Pharm. Acta Helv., 41 (ll), 622-40 (1966); Chem. Abstr., 66, 22252y (1967). (1745) Zbid., 41 (12), pp 658-69; Chem. Abstr., .66, 407444 (1967). (1746) Pivovarov, G. A., Lab. Delo, 1966 (ll), p656; Anal. Abstr., 15, 960 (1968). (1747) Piwowarska, B., Gregorowicz, Z., Buhl, F., Chem. Bnal. (Warsaw), 11 (51, 869-72 (1966); Chem. Abstr., 66, 7964th (1967). (1748) Plakunov, V. K., Mikrobiologiya, 34 (3), 524 (1965); Anal. Abstr., 13, 5040 (1966). (1749) Plavsak, M.,Farm. Vestnik (Ljubljana), 16 (5-8) 113-16 (1965); Chem. Abstr., 65, l0j’ (1966). 11750) Plekhan, 31. I., Babirh, P. A., Khim.-Farm. Zh., 1 (12), 37-40 (1967); Chem. Abstr., 68, 7 2 2 8 7 ~(1968). (1751) Pleschka, K., Usinger, K., Albers, C., Anaethesist, 15 ( 5 ) , 166-8 (19663; Anal. Abstr., 14, 5588 (1967). (1752) Pligin, S. G., Farmatsiya (Lloscowj, 16 ( 2 ) , 55-7 (1967); Chem. Abstr., 67, 25421j (1967). (1753) Pligin, S. G., Farm. Z h . (Kiev), 22 1.5). 79-84 11967); Chem. Abstr., 68, 81446d 11968). (1754) Pligiri, S. G., Z h . Anal. Khirn., 22 ( l ) , 145-50 (1966); Chem. Abstr., 66, y8,yx f (1067),. 11755) Zbid.. 22 17). DU 1098-102: Chetn. Abstr., 67, 102826;. i i 9 6 7 j . (1756) Poethke, K., Biederinann, J., Pharm. Zentralh. Deut., 104 14), 225 (1965); Anal. Abstr., 13, 4377 (1966). (1757) Poethke, Pi-., Hoffmann, J., ibid., 104 ( S ) , p 559; Anal. A b s t r , 13, 7065 (1966). (1758) Poethke, IT.,Koehne, H., Pharmazie, 22 ( l l ) , 639-43 (1967); Chem. Abstr., 68, 53298p (1968). (1759) Poethke, IT., Preussler, >I.,Pharm. Zentralh. Deut., 105 ( S ) , 505-14 (1966); Chem. Abstr., 16793e (1966). (1760) Poetter, H., Voigt, R., Pharmazie, 21 (5), 291-5 (1966); Chem. Abstr., 65, 866% 11966). (1761) Zbid., 22 (4))198-202 (1967); Chem. ilbstr., 67, 848911; (1967). (1762) Poey, S. B., Hwa, B. G. K., Sz~ara Pharm., 10 (3) 77-83 (1967); Chem. dbstr., 68, 6 2 0 3 ~(1968). (1763) Poey, S. B., Ong, K. L4.,ibzd., pp 61-5; Chem. Abstr., 67, 111468m 11967). (1764) Pogacar, P., Kienle, B., Krapp, P., Luehrsen, K., J . Chromatogr., 29 ( l ) , 287-92 (1967). (1765) Poggendorf, .4., Mundstock, H., Seidlein, H. J., Pharm. Prax. (Berlin). 1966 ( 2 ) , pp 29-32; A d . Abstr.. 14, 3557 (1967). (1766) Pohloudek-Fabiiii, R., Furtig, W., Pharmazie. 20 ( 3 ) , 128 (1965~;Anal. Abslr., 13, 3841 (1966). (1767) Pokorny, J., Zwain, €I.,Cesk. Farm., 15 i5), 232-4 11966); Chem. Abstr., 65, l5158e (1966). 117681 Pol. H. J. van der. Pharm. Weekblad, 101 (24), 531 fl966): Anal. Abstr., 14, 6393 (1967). (1769) Polaczek, L., Kuszczak, H., Chem. Anal. (Warsaw), 1 1 (5), 873-7 (1966); Chern. Abstr., 66, 796302 11967). 11770) Polizzi-Schiarone. 11..Boll. Chzm. Farm., 104 (12)) 81‘2 (1965); Anal. Abstr., 14, 21798 (1967). (1771) Polkinghorn, F., Solutions (Ann Arbor). 6 14). 8-10 119671. (1772) Polli, G. P., Ravin, L. J., J.Pharrn. SCZ.,56 ( 7 ) ,781-803 11967). Sci., (1773) Polonia. J. A. de B., Rev. Port. Farm., 17 12), 115-28 (1967); Chem. Abstr., 67, 108819w 11967). (1774) Pomazanska, Pomazamka, T., Zyzynski, Ti., Diss. Pharm., 17 13). 319-21 11965): Chem. .4bstr., 65, 572f (1966) \-Y...

(1775) Ponder, C., J . Pharm. Sn’., 57 (3), 467-9 (1968). (1776) Ponomareva, Z. P., Sb. Xaztchn. Tr., Tsentr. Aplechn. Nauchn.-Issled. Inst., 6, 133-40 (1964); C’hem. Abstr., 65, 8673b 11966). (1777) Pons, J. -4.,Publ. Inst. Invest. Microquim. Cniv. iVac. Litoral (Rosario, Arg.), 26, 215 (1965); Anal. Abstr., 13, 5586 11966). (1778) Popa, I., Voicu, A., Teodorescu, C., Frlrmacia (Bucharest), 14 (5), 269-72 (1966); Chem. Abstr., 65, 10427f (1966). (1779) Popescu, D., Gamentzi, V., Vaeni, AI., Rev. Chem. (Bucharest), 17 (6), 373-4 (1966); Chem. Abstr., 65, l5156b (1966). (1780) Popesru, D., Ionescu-Solomon, I., Vaeni, &I.,ibid. ( 3 ) ,p 178; Chem. Abstr., 65. 6997a 11966). (178i) Popescu, D., Vaeni, ill., ibid. ( 2 ) , p 108; Anal. Abstr., 14, 3548 (1967). (1782) Popova, 1‘. I., Farmatsiya (MosCOW), 16 (31, 62-5 (1967): Chem. Abstr.. 67, 76232f 11967). 11783) Pouova, V. I.. Farm. Zh.. Khark.. 1966 15j, pp 19-21; Bnal. Abstr., 14; 7797 11967). (1784) Popova, V. I., Farm. Zh. (Kiev), 22 (l),36-9 (1967); Chem. Abstr., 67, 2 5 4 3 9 ~(1967). (1785) Ibid. (2), pp 28-31; Chem. Abstr., 67, 47122q (1967). 11786) PoDova. V. I.. Kramareiiko. V. P.. ibid., 21A(2),27-31’(1966) ; Chem.’Abstr.i 65, 3672E (1966). (1787) Popova, Y., Popov, C., Ilieva, M., J . Chromatogr., 24 (I), 263-4 (1966). (1788) Popovic, It., Nikolic, K., Acta Pharm. Jugoslav., 17 ( 2 ) , 77-80 (1967); Chem. Abstr., 67, 940491” 11967). (1789) Popovici, V., Schweiger, A., Spitzer, A., Farmacia (Biicharest), 13 (6), 353 (1965); Anal. Abstr., 13, 5784 (1966). (i790j Popper, E., Florean, E., Marinescu, I., Pharmazie, 22 ( 8 ) , 442-3 (1967); Chem. Abstr., 68, 16196h (1968). (1791) Porebski. J.. Jarosinska. D.. Diss. Pharm. Pharmacol., 18 (6), 6”-9 i1966); Chem. Abstr., 67, 25424n (1967). (1792) Porter, G. S., Beresfcrd, J., J . Pharm. Pharmacol., 18 (4))223 (1966). (1793) Porush, I., Shimamura, A., Takahashi, L. T., J . Pharni. Sci., 54, 1809 (1965). (1794) Posgay, E., Acta Pharm. Hung., 35 12), 68 (1965); Anal. Abstr., 13, 5777 (1966). (1795) Posgay, E., Zoltai, E., ibid., 36 (41, 172-9 11966); Anal. Abstr.. 14. 6381 (1967). (1796) Potter, G. D., Guy, J. L., Proc. SOC.E m . Biol. M e d . . 116 ( 3 ) . 658-60 (1964); ‘Anal. Abstr.,’ 12, 5298 (1965). (1797) Potter, E., Phannazie, 20 (I]), 737 (1965);Anal. Abstr., 14, 1647 (1967). (1738) Pozdnvakova, V. T., Denisova, E. V., Farm. -Zh. (Kiev], 22 ( l ) , 46-50 11967); Chem. Abstr., 67, 1488613 (1967). (1799) Pozdnyakova, V. T., Onishchenko, Y.V., abid. (6), pp 23-5; Chern. Abstr., 68, 53315s (1968). (1800) Pozdnyakova, V. T., Znaevs’ka, V., zbid. (2), p 21; Chem. Abstr., 67, 67608f (1967). (1801) Pozetti, G. L., Trib. Farm. (Brazil), 35 11-2), 20 (1967); Chem. Sbstr., 68, 33235n (1968). (18021 Prabhakar, V. S., Handa, K. L., J . Proc. Inst. Chem. (India), 37 \ 2 ) , 65 11965); Anal. Abstr., 13, 5780 (1966). (1803, Pradhan, T.K., ibid., 39 (4), IS3 (1967); Chem. Abbtr., 67,102818~(1967). (1804) Pieacott, G. C., J . Pharm. Sci., 55 ‘4),423 (1966). (1805) Preussler, ll., Pharm. Zentralh. Deut., 103 (6), 409 (1964); Anal. Abstr., 12, 5411 (1965). (18061 Pribilla, O., ilrzneim.-Forsch., 14 VOL. 41, NO. 5, APRIL 1969

0

239 R

(6), 723 (1964); Anal. Abstr., 12, 5300 (1965). (1807) Prista, L. N., Polonia, J., Costa, A. S., Rlorgado, R. R., A n a i s Fac. Farm. Porto, 25, 59 (1965); Chem. Abstr., 67, 57OSe (1967). (1808) Probst; G. W.,Brown, W. F., Henry, H. J., J . Pharm. Sci., 55 (12), 1408 (1966). (1809) Prochazka, V., Kavka, F., Prucha, hl.. Pitra. J., Cesk. F a r m . 14. 154 11965):Chem. Abstr.. 66.108254~(i967). (1810) Ibid., 15 (7), '363 (1966); Chem. Abstr., 66, 31976q (1967). (1811) Proll, J., Plessing, H., Ernaehrungsforschuna, 9 (4). 513 (1964): Chem. Abstr., 63, 54539 (1965). (1812) Prosser, A. R., Sheppard, A. J., Libby, D. 4.,J . Ass. Ofic. Anal. Chem., 50 (6), 1348 (1967). (1813) Przyborowski, L., Diss. Pharm. Pharmacol., 18 ( 5 ) , 505 (1966); Chem. Abstr., 67, 14894q (1967). (1814) Puech, A., Delonca, H., J. Pharm. Belg., 20 (11-12), 484 (1965): Chem. Abstr.. 65. 5 7 3 ~11966). (1815) Pueih, A., Jacob, ll., Delonca, H., ibid., 22 (7-8), 264 11967); Chem. Abstr., 67, lll502t (1967). (1816) Puech, A., Masse, J., Jacob, Al., Trav. SOC.Pharm. Montpellier, 26 ( 3 ) , 275 11966): Chem. Abstr.., 67., 94030t 11967). 817) Pungor, E., Szabo, K., Magy. Kem. Foly., 72 ( 5 ) , 227 (1966); Anal. Abstr., 14, 5461 11967). 818) Pungor, E., Szasz, A., llolnar, E., Acta Pharm. Hung., 36 (4),164 (1966); Chem. Abstr., 65, 1 6 7 9 2 ~(1966). 819) Pungor, E., Szasz, A, Papp-Molnar, E., Acta Chim. Acad. Sci. Hung., 53 (3), 250 (1967); Chem. Abstr., 67, 111379h (1967). 820) Quesenberry, R. O., Donaldson, E. hl., Ungar, F., Steroids, 6 (a),167 (1965). 821) Quesenberry, R. O., Ungar, F., Anal. Biocheni.. 8 12). 192 (1964). (1822) Rabek, V.', J . Chromatogr., 33 (l), 186 (1968). (1823) Raber, H., Sci. Pharm., 34 ( 3 ) , 202 (1966); Chem. Abstr., 66, 22249c (1967). (1824) Ibid., 35 ( 3 ) , 220 (1967); Chem. Abstr., 68, 6 2 0 4 ~(1968). (1825) Ibid. (4),p 297; Chem. Abstr., 68, 814332 (1968). (1826) Rabitzsch, G., Tambor, E., Pharmazie, 22 ( l l ) ,668 (1967); Chem. Abstr., 68, 72275, (1968). (1827) Radecks, C., Nigam, I. C., Can. J . Pharm. Sci., 1 ( l ) , 17 (1966). (1828) Radecka, C., Nigam, I. C., J . Pharm. Sci., 55 ( 8 ) , 861 (1966). (1829) Ragazzi, E., Veroneqe, G., Farmaco, E d . Prat., 22 ( 2 ) , 96 (1967); Chem. Abstr., 66, 98469~(1967). (1830) Ragland, J. B., Kinross-Krught, V. J., ASAL.CHEM.,36 (i),1356 (1964). (1831) Ragland, J. B., Kinross-Wright, Ir. J., Ragland, R. S., Anal. Biochem., 12 ( l ) ,60 (1965). (1832) Rahalkar, A,, Gopalkrishnan, Ii. S., Hzndiistan Antibiot. Bull., 9 (4), 259 (1967); Chem. Abstr., 67, 84902p (1967). (1833) Raigorodskaya, I-.Y., Bashkovich, 4.P., Kul'bakh, IT. O., Khzm-Farm. Zh., l i 6 ) , 42 (1967):Chem. Abstr.. 67.1202136 (1967). 11834'1 Raman. P. B.. Avrimov. R.. MeKiven, N. L:, Dorfman, R. I.; Steroids, 6 ( 2 ) , 177 (1965): .835) Ramotowski, S., Szczesniak, XI., Acta Polon. Pharm., 24 (6), 605 (1967); Chem. Abstr., 68, 62762n (1968). -836) Ramseyer, J., Williams, J. S., Hirschmann H., Steroids, 9 (4), 347 (1967). (1837) Ramusino, F. C., Cecchetti, G., Ann. Inst. Super. Sanita, I (11-12), 764 (1965): Anal. Abstr., 14, 1664 (1967). 240 R


(1838) Rsngone, R., Farmaco, Ed. Prat., 21 ( 5 ) , 275 (1966); Chem. Abstr., 65, 8676e (1966). (1839) Rangone, R., La Fata, S., ibid. ( l ) ,p 30; Anal. Abstr., 14,2783 (1967). (1840) Rao, E. V., Narayanan, 31. N., Indian J. Pharm., 30 (3), 70 (1968); Chem. Abstr., 68,89893t (1968). (1841) Rapaport, L. I., Kostinskaya, A. D., Farrnatsiya (PIIoscow), 16 (I), 53 (1967); Chem. Abstr., 66, 98517~'(1967). (1842) Rapaport, L. I., Shakh, T. I., Farm. Zh. (Kiev), 21 (6), 22 (1966); Cheni. Abstr., 66, 98530h (1967). (1843) Rapaport, L. I., Verzina, G. V., ibid ( l ) ,p 33; Chem. Abstr., 65, 5304h 11966). (1844) Ibid. ( 3 ) , p 24; Chem. Abstr., 65, 1 5 1 6 2 ~(1966). 11845) Ibid. (4),p 30; Chem. Abstr., 65, 19926h (1966). (1846) Ibid., 22 (41, 62 (1967); Cheni. Abstr., 67, 1028465 (1967). (1847) Rapp, J. P., Eik-Nes, K. B., Anal. Biochem., 15 13), 386 11966). (1848) Rapp, J. P., Eik-Xes., K. B., J . Gas Chromatogr., 3 (71, 235 (1965). (1849) Rasero, L. J., Skauen, D. Xl., J. Pharm. Sei., 56 (6j, 724 (1967). (1850) Ratajewicz, D., Chem. Anal., 1 1 (5)- 929 11966): Anal. Abstr.. 15. 440 (1968). (1!5l) Ratajewiu, D., Kaksmundzki, A, zbid., 10 ( 3 ) ,361 (1965);Anal. Absir., 13, 5167 (1966). (1852' Raut, V. S., Gagrat, F. J., Banerjee, D., Indian J . Phurm., 28 (9), 250 (1966); Chem. Abstr., 66,31991~(1967). (1853) Raval, X. K., Parrott, E. L., J . Pharm. Sci., 56 (21, 274 (1967). (1854) Raven. J. L.. Barkhan. P.. Lancet. 1966, p 1678; Anal. Abstr., '15, 884 (1968). (185.5) Raymakers, A., Pharm. Tijdschr. Belg., 43 (9), 185 (1966); Cheni. Abstr., 66, 40749v (1967). (1856) Recchi, N . V., C o n f . I n t e r a m . Radioquim., 1st Montevideo, 1963,p 307; Chem. Abstr., 65, 5740 (1966). (1857) Regdon, G., Selmecxi,B., Kedvessy, G., Phurm. Zentralh. Deut., 105 (lo), 6 ~ 8 (1966); Chem. Abstr., 66,31981n (1967). (1858) Regdon-Kiss, E., Kata, IT.,ibid., 106 ( 3 ) , 138 (1967); Chem. Abstr., 66, 108310~(1967). (1859) Rehder, K., Forbes, J., Hessler, O., Gossmann, K., Anaethesist, 15 ( 5 ) , 162 (1966); Anal. Abstr., 14, 5700 (1967). (1860) Rehn, B. IT., J . Ass. O$lc. Anal. Chem., 50 13), 660 (1967). (1861j Rehse. Ii., Deut. Spotheker-Ztg., 107 (43), 1530 (t967); Chem. dbstr., 68, 24571s 11968). (1s62) Reimer., F., Arch. Pharm. Chemz, 74 ( I ? ) , 531 (1067); Chem. Abstr., 67, 67624h (1967j. (1863) Reisch, J., Pharmazie, 21 ( 3 ) , 183 11966); Chem. Abstr., 65, 5306s (1966). (1864) R e i i c h , J . , F i t z e k , A . , D e u t . B~otheker-Zto.. 107 139). 1358 (19671: C h m . dbstr.; 68, 4 3 1 3 7 ~(1968). (1865) Reisch, J., Sovak, I., Szendrei, K., JIinker, E., Phurmazze, 22 (4), 205 (1967),Chem. ilbstr., 67,111463 (1967). (1866) Reisch, J., Tittel, G. L., Perlick, J., Deut. ilpofheker-Ztg.,, 105, 575 (1965); Chem. A b s t r , 66, 40436~(1067). (1867) Reisch, J., Walker, H., Phannazie, 21 i s ) , 467 (1966); Chem. dbstr., 66, 2223411 (196'7). (1868) Rekker, R. I?., Doorenbos, H. J., Xauta, K.T., Pharnz. Weekblad, 102 (371, 946 (1967); Chem. Abstr., 67 102847g (1967). (1869) Remsova, lI., Kracmai, J., Cesk. Farm., 15 (6), 294 (1966); Chem. Abstr., 66, 14074b (1967). (1870) Rene, M.,Bull. SOC.Pharm. Lzlle, 1966 ( 2 ) ,p 51; Chem. Abstr., 67,102812s 11'3671. \

~~

(1871) Repole, R., Gasbarro, R., hlaglione, S., Rossi, P., Rass. Med. Sper., 12 (4), 199 (1965); Chem. Abstr., 65, 15161b (1966). (1872) Resnick, G. L., Corbin, D., Sandberg, D. H., ANAL. CHEY., 38 (4),582 (1966). (1873) Resta, C., Zema, >I., Braidotti, L., Farmaco, Ed. Prat., 23 ( l ) ,34 (1968); Chem. Abstr., 68, 53231m (1968). (1!74) Ibid. (2), p 62; Chem. Abstr., 68, i2237i (1968). (1875) Reubke; R., Mollica, J. A., J . Pharm. Sci., 56 ( 7 ) , 822 (1967). (1876) Reusser, P., Fresenius' 2. Anal. Chern., 231 (4),272 (1967); Chem. Abstr., 68,33234nz (1968). (1877) Reuter, G., Heller, P., Pharm. Zentralh. Deut., 105 (9), 597 (1966); Chem. Abstr., 66,5719j 11967). (1878) Reyes, R. E., Gonzalez, A., A n . Real SOC.Espan. Fis. Quint., Ser. A, 62 (9-10), 981 (1966); Anal. Abstr., 15, 2099 (1968). (1879) Reynolds, L. M.,Kessler, I\*. V., Christian, J. E., Ziemer, P. L., J . Pharm. Sci., 56 (4),437 (1967). (1880) Rezei, C., Marinescu, I., Florean, E., Phurmazie, 21 i l l ) , 675 (1966);C h e m Abstr., 66, 985601 (1967). (1881) Rhodes, H. J., Blake, hl. I., J . Pharm. Sci., 56 ( l o ) , 1352 (1967). (1882) Richter, G., Hauenstein, H., Deut. Apotheker-Ztg., 107 (48), 1751 (1967); Chenz. Abstr., 68, 43197r (1968). (1883) Richter, J., Ropte, D., Pharmazie, 21 18), 495 (1966); Chem. Abstr., 66, 14068c (1967). (1884) Richter, K., Vecchi, M., Vetter, IT., Walther, IT., Helv. Chim. Acta, 50 ( 2 ) ,364 11967); Chem. Abstr., 66,98537r (1967). (1885) Ricketts, C. R., Suture, 210 (5041), 1113 11966); Chem. Sbstr., 65, l5163h 11966). (1886) Rieder, J., Arzneim.-Forsch., 15 ( l o ) , 1134 (1965); Anal. Abstr., 14, 866 (1967). (1887) Rifino, C. B., hlonte-Bovi, A. J., Sciarra, J. J., J . Pharm. Sci., 54 ( 3 ) ,413 (1965). (1888) Rimada, 4.T., Publ. Inst. Invest. Mocroquirn. Univ. Xac. Litoral (Rosario, d r g . ) , 27, 197 (1964-65); Chern. Abstr., 68, 81443a (1968). (1889) Rink, M.,Krebber, D., Pharmazie, 20 16), 349 (1965);Anal. Abstr., 13, 5794 (1966). (1890) Ripaii, R., Suteu, A, Finta, Z., Studza L'niv. Babes-Bolyai, Ser. Chem., 12 (I), 7 5 (1967); Chem. Abstr., 68, 1 6 1 7 5 ~(1968). (1891) Risinger, G. E., Hsieh, H. H., Chein. Znd. (London), 38, 1600 (1966). (1892) Ristic, N., Arhzv Farm. (Belgrade), 16 12), 114 (1966); Chem. .4bstr., 66, 58857n (19671. (1893) Roberts,'J. I., J . Ass. O ~ CAnal. . Chem., 50 ( 3 ) ,658 (1967). (1894) Roberts, L. A., ibid., 49 (4),837 (1966). (1895) Ibid.. 50 13). 680 (1967). (1896) Roder, E.,' 'Deut. Apotheker-Ztg., 105 ( 3 ) , 7 3 (1965); Bnal. Abstr., 13, 5168 (1966). (1897) Rodionovskaya, E. I., Rozenfel'd, G. S.,Baikina, V. >I., Trakhtenberg, I>. JI., Antibiotiki, 11 ( 8 ) , 705 (1966); Chem. Absfr., 65, 16790f (1966). (1898) Roeder, E., Deut. Apotheker-Ztg., 105 (40), 1378 (1965); Chem. Abstr., 65, 2069b (1966). (1899) Ibid., 107 (29), 1007 (1967); Chem. Abstr., 68, 33243p (1968). (1900) Roeder, K., llutschler, E., Rochelmeyer, H., Pharm. Acta Helv., 42 ( 7 ) , 407 (196i); Chem. Abstr., 67, 76334r (1967).

(1901) Roets, E., Vanderhaeghe, H., Pharm. Tijdschr. Belg., 44 (4), 57 (1967); Chem. Abstr., 67, 67633k (1967). (1902) Rogavitz, H., J . Ass. Ofic. Anal. Chem., 50 (l),29-37 (1967). (1903) Rogers, A. R., J. Pharm. Pharmacol., 17 (5), 325 (1965). (1904) Rogovskii, D. Y., Farmatsiya (hloscow), 16 (6), 47 (1967); Chem. Abstr., 68, 59897s (1968). (1905) Rogovs’kii, D. Y., F a r m . Zh. (Kiev), 21 (2), 34 (1966); Chem. Abstr., 65, 2065h (1966). (1906) Ibid. (3), p 17; Chem. Abstr., 65, 16794d (1966). (1907) Rokarh, Z. S., Kramarenko, V. P., ibid., 22 (l), 26 (1967); Chem. Abstr., 67, 67627m (1967). (1908) Rolski, S., Zakrzewski, Z., Neumann, Z., Farm. Polska, 22 (8), 571 (1966); Chem. Ahstr., 66, 7 9 6 1 7 ~(1967). (1909) Rolski, S., Zakrzewski, Z., Sochon, J., ibid. (9), p 641; Chem. Abstr., 66, 79618h (1967). (1910) Rolski, S., Zakrzewski, Z., Szulczyk, T., ihid., 23 (3),251 (1967): Chem. Abstr.. 68. 62082 119681. (191i) Rolski, S.,’ Zakrzewski, Z., Zawistowska, D., ibid., 22 (lo), 725 (1966); Chem. Abstr., 67, 572699 (1967). (1912) Romanenko, E. V., Prikl. Biokhim. Mikrobiol., 2 (3), 308 (1966); Chem. Abstr., 65, 5304a (1966). (1913) Roos, A. PVI. de, Pharm. Weekblad, 102 (42), 1071 (1967); Chem. Abstr., 68, 6240d (1968). (1914) Zhid. (49), p 1302; Chem. Ahstr., 68, 53287j (1968). (1915) Rosenstein, J., J . A s s . Of. Agr. Chem., 47 (3), 469 (1964). (1916) Rossa. P.. Acta. Pharm. Huna.. 35 (4); 1-75 (1965); Anal. Ahstr., 13,”6472 (1966). - -, \ - -

(1917) Rossetti, V., Biochim. Appl., 12 113 (196.5). Zbid., 13 ( 5 ) , 223 (1966); Anal.

E. O., Deut. Apothek&Ztg., ’105, 1048 (1965); Chem. Abstr., 66, 4 0 7 6 2 ~(1967). (1921) Rotzsch, W., Koehler, H., Martin, H., Hoppe-Seyler’s 2. Physiol. Chem., 348 (7), 939 (1967); Cherrl. Abstr., 67, 94443e (1967). (1922) Roushdi, I. M., Abdine, H., Sayed, \I-.S. A.. J. Pharm. Sci. U. Arab. Rev.. 5, 91 (1964) (Publ. 1965); Chem. Absir.; 65, 16792b (1966). (1923) Rowson, J . ?*I.,Analyst (London), 92 (1098), 593 (1067). (1924) Rowson, J. ?*I.,Pharm. TYeekhlad, I00 1-51),1500 (1965); Anal. Abstr., 14, 2195 (1967). (1925) Rozsa, P., Acta Pharm. Hung., 37 (4), 145 (1967);Cheni. Ahstr., 67,102835b (1967). (1926) Rozynska, lI., Wilczynska, I., dcta Polon. Pharm., 22 (4), 341 (1965); Anal. Abstr., 13, 6496 (1966). (1927) Ihid., 24 ( l ) , 45 (1967); Chem. Ahstr., 67, 676490 (1967). (1928) Rozynska, lI.,Kojcik, Z., Zyzynski, W., Diss. Pharm. Pharnzacol., 18 (3), 315 11966). (1929) Rubinskaya, T’. G., Sb. Kauchn. Tr., Tsentr. Aptechn. Nauchn.-Issled. Inst., 7-8, 124 (1966); Chem. Abstr., 68, 1 6 1 7 3 ~(1968). (1930) Ruckert, A., Schone, J., Pharmazie, 22 ( l ) ,26 (1967); Anal. Ahstr., 15, 2914 ( 1968). (1931) Ruecker, G., Arch. Pharm., 299 (81, 688 (1966); Chem. Ahstr., 65, 16791a (1966). (1932) Ruecker, G., Fresenius’ 2. Anal. Chem., 229 (a), 340 (1967); Chem. Abstr., 67, 111513s (1967).

(1933) Ruecker, G., Natarajan, P. N., Arch. Pharm. (IT‘einheim), 300 (3), 276 (1967);Chem. Abstr., 66,108300~(1967). (1934) Rusiecki, W., Henneberg, M., Acta Pobn. Pharm., 23 (a), 117 (1966); Chem. Abstr., 65, l206lf (1966). (1935) Rutkonrska, U., Wojsa, K., Herba Pol., 12 (2), 101 (1966); Chem. Abstr., 66, 79638h (1967). (1936) Ruzickova, J., Chladek, K., Baloun, J., Farm. Obzor, 35 (lo), 433 (1966); Anal. Abstr., 15, 1002 (1968). (1937) Ryabchikov, D. I., Volynets, XI.P., Zh. Anal. Khim., 21 ( l l ) ,1348 (1966); Chem. Ahstr., 66, 43340r (1967). (1938) Rgbak, E. I., Lisunkin, Y. I., Kalinin, 0. If.,Farmakol. Toksikol., 29 (3), 368 (1966);Chem. Ahstr., 65,13453h (1966). (1939) Sa, L. ?*I.de, Rev. Fac. Farm. Bioquim. Univ. Suo Paztlo, 4 ( 2 ) ,401 (1966); Chem. Ahstr., 67, 84016s (1967). (1940) Ihid., 5 (l),231 (1967);Anal Abstr., 15, 2918 11968). (1941) Saba, R., Monnier, D., Khalil, F. R., Pharm. ActaHelv., 42 (6), 335 (1967); Chem. Abstr., 67, 67665s (1967). (1942) Sabath, L. D., Estey, V. J., Finland, M., Appl. Microbiol. 15 (3), 468 (1967). (1943) Sabri, M.I., Rao, V.K. AI., Indian J . Technol., 4 (6), 191 (1966); Chem. Abstr., 65, 8679e (1966). (1944) Saccani, F., Boll. Chim. Farm., 105 ( 2 ) , 134 (1966); Chem. Abstr., 65, 571h

(1966) Salvesen, B., and Glendrange, J. H., Medd. Norsk Farm. Selskap, 28 (10-11), 272 (1966); Chem. Abstr., 66, 68866e (1967). (1967) Salvesen, B., Johnsgard, &I.,ibid., p 279; Chem. Abstr., 66,118892h (1967). (1968) Samejima, M., Sugimoto, I., Utsumi, I., Yakugaku Zasshi, 86 (lo), 900 (1966): Chem. Abstr... 66., 221502, (1967). (1969) Sanchez, E., Chemia (Buenos Aires), 19 (116), 13 (1966); Chem. Abstr., 65, 128319 (1966). (1970) Sanchez, E., Theumann, D., ib-id., p 9; Chem. Abstr., 65, 12831b (1966). (1971) Sanderfer, P. O., Diss. Ahstr., 26 (lo), 5725-6 (1966); Chent. Abstr., 65, 37019 (1966); Univ. Microfilms (Ann Arbor, Alich.), Order No. 66-2045, 90 PP. (1972) Sano, Y.,Somura, S.,Kamio, Y., Omura, S., Hata, T.,J . Antibiot. (Tokyo), Ser. A, 20 (6), 344 (1967); Chem. Ahstr., 68, 6 2 6 3 3 ~(1968). (1973) Santopadre, G., Bolton, S., J . Pharm. Pharmacol., 19 ( 8 ) , 550 (1967). (1974) Sanyal, S. K., Indian. J. Pharm., 27 (5), 149 (1965); Anal. Abstr., 13, 5166 (1966). (1975) Sanyal, S. N., J . Proc. Znst. Chem. (India), 38 (4), 167 (1966); Chem. Abstr., 66, 57952 (1967). (1976) Sapronov, A. R., Kharin, S. E., Sakh. Prom., 41 (6), 55 (1967); Chem. Abstr., 67, 1088649 (1967). (1 966) (1977) Sarfaty, G. A., Lipsett, 11. B., (1945) Zhid., 106 (9), 625 (1965); Chem. Anal. Biochem., 15 ( l ) , 184 (1966). Abstr., 68, 24523c (1968). (1978) Sarsunova, M., Ba, T. T. H., Cesk. (1946) Sachvieh, H., Richter, J., SeidenFarm.. 15 (10). 522 (1966):Chem. Ahstr.. glanz, G., Arzneimittelstandardisierung, 66, 108316j (1967). 7 ( 8 ) , 441 (1966); Chem. Abstr., 67, (1979) Sarsunova, hl., Chi, K. T. K. 4 7 1 2 7 ~(1967). ibid. (9), p 474; Chem. Abstr., 66, 79621s (1947) Sachaeh, H., Seidenglanz, G., (1967). Richter, J., ibid. (12), p 697; Chem. (1980) Sarsunova, AI., Kakac, B., Schwarz, Ahstr., 67, 25428s (1967). V., Maly, V., Protiva, J., Pharmazie, 21 (1948) Safarik, L., Cesk. Farm., 15 ( i ) , (12), 752 (1966); Chem. Ahstr., 66, 360 (1966); Chem. Abstr.. 66. 31974% 108305e (1967). (1967). (1981) Sarsunova, RI., Schwarz, V., Feke(1949) Said, F., Smer., AI. RI., Girgis, teova, E., Protiva, J., Pharmazie, 21 K. K., George, Z. A., Analyst (London), (4),219 (1966); Chem. Abstr., 65, 5303h 90, 750 (1965). (1966). (1950) Said, F., Salah, 11. K., Girgis, P., (1982) Sarudi, I., Elelmiszervizsgalati ibid., 91 (1084), 459 (1966); Chem. Kozlemen., 12 (I), 35 (1966); Chem. Abstr., 65, 15160b (1966). Abstr.. 65. 18430d (1966). (1951) Saiki, Y., Saito, T., Sasaki, H., (1983) Saru‘di, I., Pharm. ’Zentralh. Deut., Fukushima, S.. Yakuaaku Zasshi. 87 105 (2), 87 (1965); Chem. Abstr., 65, 573e (1966). (12), 1524’ (1967): CXem. Ahstr.,’ 68, 814402 (1968). (1984) Ibid., 106 (4), 217 (1967); Chem. (1952) Saint-Firmin, A. R., Paris, R. R., Abstr., 67, 36386c (1967). .I. Chromatogr., 31 ( l ) ,252 (1967). (1985) Sasaki, T., J . Chromatogr., 24 (2) (1953) S a k a g u c h i , T . , T a g u c h i , I < , , 452 11966). Yoshida, T., Runseki Kaaaku. 14,206R(1986) Satiadarma, K., Suara Pharm., 19 20R (1965); -4nal. Agstr., 14, 1841 il), 1 (1966); Chem. Ahstr., 65, 1 5 1 6 4 ~ (1967). (1966). (1954) Sakurai, K. N., Toshii, E.. Kubo, (1987) Sato, H., Shimamine, M.,Eisei K., Yakugnku Zasshi, 84 (12), 1166 Shikenjo Hokoku, 83, 50 (1965); Chem. (1964); Anal. Abstr., 13, 3769 (1966). Abstr., 65, 19932e (1966). (1955) Salim, E. F., Bodin, J. I., Zimmer(1988) Sato; K., Tonooka, K., Yakugaku man, H. B., Reisberg, P., J . Pharm. Sci., Zasshi, 87 (3), 231 (1967); Chem. Ahstr., 55 (13), 1439 (1966). 67. 36378b (1967). (1956) Salim, E. F., Booth, R. E., ihid., (1989) Sattler, H., Pharm. Ztg., 111 (39), 56 ( 5 ) , 623 (1967). 1395 (1966); Chem. Abstr., 66, 40761t (1957) Salim, E. F., Deuble, J. L., Papa(1967). riello, G., ibid., 57 (2), 311 (1968). (1990) Sauciuc, A., Rev. Chim., 17 (?), (19.58) Salim, E. F., Ebert, \I*. R., ibid., 110 (1966);Anal. Ahstr., 14,3511 (196,). 56 (9), 1162 (1967). (1391) Sauciuc, A., Ionesru, L., Rev. Chim. (1959) Salim, E. F., Felker, W. S.,ihid. (Bucharest), 17 (I), 47 (1966); Anal. 17), p 886. Ahstr., 14, 3510 (1967). (1960) Salim, E. F., Hilty, W. IT., ihid. (1992) Sauciuc, A., Ionescu, L., Albu13),p 385. Budai, lI., ihid., 18 (4), 237 (1967); (1961) Ihid. (4), p. 518. Chem. Abstr., 67, 67647t (1967). (1962) Salim, E. F., Martin, A. E., ibid. (1993) Savopol, E., Balliu, S., Boteanu, (6), p 748. S., Coroi, S., Setlacec, E., Farman‘a (1963) Salini, E. F., Ortenblad, B., ihid. (Bucharest), 14 ( 5 ) , 277 (1966); Chem. 112), p 1645. Ahstr., 65, 10429h (1966). (1964) Salim, E. F., Shupe, I. S., ibzd., (1944) Sawicki, B., Janik, B., Acta Polon. 55 (111, 1289 (1966). Pharm., 23 (6), 573 (1966); Chem. Ahstr., 66, 108296~(1967). (1965) Salim, E. F., Weaver. J. R.. Chafetz. L., ihid., 56 (8), 1001 (1967). (1995) Scemama, hl., Ann. Pharm. Fr., \ - - - - / .

VOL. 41, NO. 5, APRIL 1969

241 R

25 (l), 37 (1967); Anal. Abstr., 15, 2863 (1968). (1996) Schachter, M. M., Ma, T. S., Mikrochim. Acta, 1966 (1-2), p 55; Anal. Abstr., 14, 4029 (1967). (1997) Scheffer, F., Kickuth, R., Fresenius 2. Anal. Chem., 230 (4), 254 (1967); Chem. Abstr., 68, 35631n (1968). (1998) Schenk, G. H., Warner, P., Bazzelle, R., ANAL.CHEM.,38 (i),907 (1966). (1959) Schilcher, H., Deut. Apotheker-Ztg., 105 (32), 1067 (1965); Anal. Abstr., 13, 7054 (1966). (2000) Zbid., 106,231 (1966) ; Chem. Abstr., 67, 36358~(1967). (2001 Zbid., 107 (25), 849 (1967); Chem. Abstr., 67, 102837d (1967). (2002) Schill, G., Modin, R., Persson, B. A., Acta Pharm. Suecica, 2 (2), 119 (1965); Chem. Abstr., 63, 4096a (1965). (2003) Schiller, P., Cesk. Farm., 15 ( 7 ) , 382 (1966); Chem. Abstr., 66, 22231r (1967). (2004) Schiller, P., Havranek, E., Hornak, Z., ibid., 16 ( i )327 , (1967);Chem. Abstr., 68, 1619% (1968). (2005) Schiller, P., Havranek, E., Svitel, J., Radiochem. Conf., Abstr. Paper, Bratislava, 1966, p 52; Chem. Abstr., 68, 161693 (1968). (2006) Schiller,’P., Synek, J., Cesk. Farm., 15 (9), 508 (1966); Chem. Abstr., 66, 79647k (1967). (2007) Schlemmer, W.,Deut. ApothekerZtg., 106 (38), 1315 (1966); Chem. Abstr., 66, 49278y (1967). (2008) Schlesinger, H. L., Pro, 11. J., Hoffman. C. M..Cohan. 11..J. Ass. O ~ CAg;. . Chem.,’48 (6), 1139’(1965). (2009) Schlitt, L., Rink, hf., Stackelberg, M. V., J . Electroanal. Chem., 13 (1-2), 10 (1967); Chem. rlbstr., 66, 5798s (1967). (2010) Schmandke, H., Nahrung, 9 (3), 381 (1965);Anal. Abstr., 13,3785 (1966). (2011) Schmerzler, E., Yu, R.,Hewitt, 111. I., Greenblatt, I. J., J . Pharm. Sci., 55, 155 (1965). (2012) Schmid, J., Pharm. Zentralh. Deut., 104 i l l ) . 715 (1965): Anal. Abstr.., 14., 1670 (1967). (2013) Schmid, W., Angliker, E., Pharnz. Acta Helv., 41 (6), 369 (1966); Chem. Abstr., 65, 5304c (1966). (2014) Schmidt, G., Huenisch, E., Deut. 2. Ges. Gerichte. Med., 57, 393 (1966); Anal. Abstr., 15, 337 (1968). (2015) Schneider. G.. J . Chromatoor.. 31 (2), 612 (1967): (2016) Schneider, II. P. G., Szereday, Z., Klin. Vochenschr., 43, 747 (1965); Anal. Abstr., 13, 6436 (1966). (2017) Schnekenburger, J., Hartikainen, I., Deut. Apotheker-Ztg., 105 (26), 861 (1965); Anal. Abstr., 13, 6469 (1966). (2018) Schoenenberger, IT, Brinkmann, R., Arch. Pharm. (Weinheim), 229 1 l l ) , 952 (1966); Chem. Abstr., 66, 4 9 2 8 1 ~ (1967). (2019) Sch>enmakers, A. W.,Tarladgis, B. G., hature, 210 (5041)) 1153 (1966). (2020) Schorderet, M.,Kapetanidis, I., hlirimanoff, A., Pharm. Acta Helv., 41 (5), 293 (1966); Chem. Abstr., 65, 5305a (1966). (2021) Ibid. (12), p 680; C h ~ mAbstr., . 66, 79651g (1967). (2022) Schrank, J., Leupin, K., d i d . (5), p 305; Chem. Abstr., 65, 5305h (1966). (2023) Schriftman, H., J . Pharm. Scz., 55 (Y), 985 (1966). (2024) Schroeder. P., Lucknei, ?*I.,Pharmazie, 21 ( l o ) , 642 (1966); Chem. Abstr., 66, 68966n (1967). (2025) Schubert, J., Chem. Tech. (Berlin), 18 ( l o ) , 633 (1966); Anal. Abstr., 15, 1041 (1968). (2026) Schulthess, A., Pharm. Acta Helv., 42 (5), 303 (1967); Chem. Abstr., 67, 25413h (1967). “

242 R

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(2027) Schulz, E. P., Posada, A., Rev. Soe. Quim. Mez., 11 (4), 114 (1967); Chem. Abstr., 67, 1202112 (1967). (2028) Schulz, E. P., Sanchez, ?*I. G., ibid,, p 117; Chem. Abstr., 68, 33240k (1968). (2029) Schumacher, H., Smith, R. L., Stagg, R. B. L., Williams, R. T., Pharm. Acta Helv., 39 (6), 394 (1964); Anal. Abstr., 12, 5413 (1965). (2030) Schunack, W.,Mutschler, E., Rochelmeyer, H., Deut. Apotheker-Ztg., 105 (44), 1551 (1965); Chem. Abstr., 65, 16791e (1966). (2031) Schunack, IT., Mutschler, E., Rochelmeyer, H., Pharmazie, 20 ( l l ) , 685 (1965);Anal. Abstr., 14,1655 (1967). (2032) Schute, J. B., Maussen, L. H. G. W. AI., Pharm. Weekblad, 101 (37), 809 (1966); Chem. Abstr., 65, 19932a (1966). (2033) Schwarm, E. F., Dabner, C., Wilson, ,J. W., Boghoeian, Xf. P., J . Pharm. Sri.. 5 5 . 744 11966). -, (2034j schwarz, v., Protiva, J., Cesk. Farm., 16 (3), 126 (1967); Chem. Abstr., 67. 67639s (1967). (2035) Schwenke, K. D., J . Chromatogr., 22 ( l ) ,187 (1966). (2036) Sciller, P., Jombik, J., Tvrda, A., Radiochem. Conf., Abstr. Papers, Bratislava, 1966, p 52; Chem. Absfr., 68, 16168a (1968). (2037) Sciortino, T., Ban, G. du, Caffau, S., Boll. Chim. Farm., 107 ( l ) , 47 (1968); Chem. Abstr., 68, 898559 (1968). (2038) Scoppa, P., Biochim. Appl., 13 (6), 274 (1966); Anal. Abstr., 15, 887 (1968). (2039) Sehgal, S. X., Singh, K., Vezina, C., Anal. Biochem., 12 ( l ) , 191 (1965). (2040) Seiler, S., Wiechmann, RI., Zh. Anal. Khim., 220 ( 2 ) , 109 (1966); Anal. Abstr., 14, 6326 (1967). (2041) Seip, W.F., Carski, T. R., Kramer, D. N., J . Pharm. Sci., 56 (10) 1304 (1967). ,. / _ _ _ _

(2042) Sekules, G., Barabino, T., Boll. Chim. Farm., 106 (111, 749 (1967); Chem. Abstr., 68, 627491, (1968). (2043) Semenov, S. M., Antibiotiki, 11 (6), 526 (1966);Anal. Abstr., 14,6377 (1967.) (2044) Senanayake, U. ?*I., Wijesekera, R. 0. B., J. Chromatogr., 32 (l), 75 (1968). (2045) Serafini, L., Corriere Farm., 21 (19), 478 (1966); Chem. Abstr., 66, 98503b (1967). (2046) Ibid. (21), p 524; Chem. Abstr., 66, 1082661 (1967). (2047) Serrano,’J. F. V., Silva, A. 111. R. da, Anais Fac. Farm. Porto, 25, 113 11965); Chem. Abstr., 67, 36388e (1967). (2048) Seth, R. K., Ray, G. K., Indian J . Pharm., 29 (4). 130 (1967):Chem. Abstr., 67, 676239 (1967). (2049) Ibid. ( 7 ) , p 203; Chem. Abstr., 67, 940292 (1967). (2050) Severen, R. van, Pharm. Tij’dschr. Belg., 44 (8),150 (1967); Chem. Abstr., 67, 120228k (1967). (2051) Severen, R. van, Delaey, J. A., Jacobs, J., ibid. ( 2 ) , p 1 7 ; Chem. Abstr., 66. 108294~(1967). (2052) Seydel, J . K., Arzneim-Forsch., 17 (71, 791 (1967); C h e m . A b s t r . , 67, 111385a (1967). (2053) Zbid., p 812; Chem. Abstr., 67, 93946j (1967). (2054) Seydel, IT., Gerecke. K.. Arzneimittelstandardisierung, 6, 38 (1965) ; Chem. Abstr., 65, 16790g (1966). (2055) Shah, R. A., Rehana, R., Anal. Chim. Acta, 33 (2), 219 (1965); Anal. Abstr.. 13. 7067 (1966’. (2056) Shah, R. A., Rehana, R., Pakistan J . Sci. Znd. Res., 9 ( 2 ) , 106 (1966); Chem. Abstr., 66, 22245~(1967). (2057) Shamotienko, G. -D., Farm. Zh. (Kiev), 22 (6), 25 (1967); Chem. Abstr., 68, 53299q (1968).

(2058) Shamotienko, G. D., Khim.-Farm. Zh., 1 (lo), 59 (1967); Chem. Abstr., 68, 33254t 11968). (2059) Shemyakin, F. M.,Timofeeva, N. G., Aptechn. Delo, 15 (6), 46 (1966); Chem. Abstr., 66,68999~(1967). (2060) SheDherd. I. S..Ross. L. F.. Morton; I. D., Chkm. Znd. (London$. 1966 (41), p 1706;Anal. A

Shikensho Hokoku, 82, 76 (1964) Chem. Abstr., 65, 15154h (1966). (2063) Shibazaki, T., Yamamoto, M., ibid., 84, 7 (1966); Chem. Abstr., 67, 14890k (1967). (2064) Ibid., p 12; Chem. Abstr., 67, 14891m (1967). (2065) Zbid., p 14; Chem. Abstr., 67, 14892n (1967). (2066) Shih, C. S., Ho, L. S., Chem. Bull. (Peking), 1965 (4),p 240; Anal. Abstr., 13, 4767 (1966). (2067) Shih, I. K., Teare, F. W., Can. J . Pharm. Sci., 1 ( l ) ,20 (1966). (2068) Zbid., p 35. (2069) Shipalov, >I. S., Shilov, Y. hi., Mekhtikhanov. S. D.. Prikl. Biokhim. Mikrobiol., 2 ’(6), 707 (1966); Chem. Abstr., 66, 7 9 6 2 0 ~(1967). (2070) Shmuilovich, L. 31.)Kustanovich, I. AI., Yanotovskiii, M.T., Med. Prom. SSSR, 20 ( i ) ,47 (1966); Chem. Abstr., 65, 1 5 1 6 1 ~(1966). (2071) Shoji, ,J., J . Chromatogr., 26 Ll), 306 (1967); Chem. Abstr., 66, 68917s 11967). (2072) Shroff, A.P., Grodsky, J., J . Pharm. Sci., 56 (41, 460 (1967). (2073) Shroff, .4.P., Huettemann, R. E., ibid. ( 5 ) , p 654. (2074) Ibid. (11), p 1530. (2075) Shteingart, 31.V., Xosovits’ka, S. A., Farm. Zh. (Kiev), 21 (2), 54 (1966); Chem. Abstr., 65, 2070a (1966). (2076) Shtol’ts, 11. G., Khim.-Farm. Zh., 1 (71, 30 (1967);Chem. Abstr., 68,22179~ (1968). (2077) Shtutman, T. M.,Lab. Delo, 1966 ( 5 ) ,p 284; 9 n a l . Abstr., 14, 5632 (1967). (2078) Shvidkii, B. I., Farm. Zh. (Kiev), 22 (I), 18 (1967); Chem. Abstr., 67, 76352~(1967). (2079) Shvidkii, B. I., Kramarenko, V. P., F n ~ m .Zh. (Kiev), 21 (31, 20 (1966); Chem. Abstr., 65, 1515921 (1966). (2080) Sidgwick, S.,,V., “Organic C,hemistry of Sitrogen, I. T. 3Iillar, H. D. Springall, Eds., 3rd ed., Oxford, 1966, p 909. (2081) Siedlanowska, H . , A c t a P o l o n . Pharm., 22 14), 333 (1965);Anal. Abstr., 13, 6499 (1966). (2082) Zbid., 23 (6)) 499 (1966); Chem. Abslr., 66, 108299f (1967). (2083) Sienkieaicz, J., Keaolowski, A, Chem. Anal. (Karaaw), 11 (6), 1243 (1966);Chem. Abstr., 66, 108298e (1967). (2084) Sienkiewicz, J., Wesolowski, A., Diss. Pharm. Pharmacol., 19 (4), 435 (1967);Chem. Abstr., 68, 432232~(1968). (2085) Sigler, K ~ ,Berka, A,, Zyka, J., h’icrochem. J . , 11 ( 3 ) ,398 (1966); Anal. Abstr., 15, 202 (1968j. (2086) Silaev, A . B., Katrukha, G. S., Trifonova, Z. P., Kharchenko, L. I., Bubenshchikova, S. X., Antibiotiki, 12 (O), 755 (1967); Chem. Abstr., 68, 24576x (1968). (2087) Silva, J. 8.F. de, Kaplan, J., J . Pharm. Sci., 55 ( l l ) , 1278 (1966). (2088) Silva, J. F. de, Koechlin, B. A., Bader, G., ibid. ( 7 ) , p 692. (2089) Silvestri, S., Farmaco., E d . Prat., 23 ( 2 ) , 84 (1968); Chem. Abstr., 68, 72291s (1968). (2090) Ibid., p 90; Chem. Abstr., 68,81441~ (1968).

(2091) Sima, Z., Damani, G., Bul. Univ. Shteteror Tiranes, Ser. Shkencat Natyrore, 21 (2), 91 (1967); Chem. Abstr., 68, 332169 (1968). (2092) Siminonovici, R., Aftalion, H., Albert, F., Rev. Chim. (Bucharest), 18 ( 8 ) , 498 (1967); Chem. Abstr., 68, 161950 (1968). (2093) Simionescu, C., Rozmarin, G., Omagiu Raluca Ripan, 1966, p 525; Chem. Abstr., 68, 49912s (1968). (2094) Simmons, D. J., Jefferies, J. P., Analyst (London), 91 (1087), 656 (1966). (2095) Simmons, D. L., Woo, H. S. L., Koorengevel, C. M.,Seers, P., J . Pharm. Sci., 55 (ll),1313 (1966). (2096) Simonyi, I., Bojthe, L., Szabo, D., Acta Pharm. Hung., 35 (4),163 (1965); Anal. Abstr., 13, 6507 (1966). (2097) Simonyi, I., Buda, L., ibid., 37 (I), 14 (1967); Anal. Abstr., 15, 2258 (1968). (2098) Simonyi, I., Kekesy, T., Bojthe, L., Brdicska, AI., ibid., 36 (6), 257 (1966); Chem. Abstr., 66, 22270c (1967). (2099) Simonyi, I., Kekesy, I., Toth, Z., Pharmazze, 22 ( l ) , 23 (1967); Chem. Abstr., 66, 118806h (1967). (2100) Sinsheimer, J. E., Keuhnelian, A. hI., J . Pharm. Sci., 55 ( l l ) ,1240 (1966). (2101) Sinsheimer, J. E., Smith,R.V.,ibid., 56 (lo), 1280 (1967). (2102) Sivitskaya, 0. K., Sb. Nauchn. Tr. Tsentr. Aptechn. Nauchn.-Issled. Inst., 6, 110 (1964); Chem. Abstr., 65, 3669a 119661. --, \ - -

(2103) Sivitskaya, 0. K., Kuleshova, RI. I., ibid., 7-8, 111 (1966); Chem. Abstr., 68, 16172s (1968). (2104) Skelly, N. E., AXAL.CHEM.,38 (i), 934 (1966). 12105) Skerrv. D. IT.. Clin. Chim. Acta. 12 ( 5 ) , 593“(1965); Abstr., 14, 846 (1967). (2106) Skora-Zietek, X., Acta Polon. Pharm., 23 (2), 123 (1966); Chem. Abstr., 65. 10426h (1966). (2107) Skora-Zietek, AI., Farm. Polska, 22 14). 254 11966): Anal. Abstr.. 14. 3547 (1967). (2108) Skora- Zie t ek , 11., Fidel us, J ., Microchim. Ichnoanal. Acta, 1965 (5-6), 988; Anal. Abstr., 14, 2303 (1967). (2109) Skorzynska, K., Acta Polon Pharm., 24 ( l ) , S5 (1965); Anal. Abstr., 15, 2152 (1968). (2110) Smith. D. J.. J . Ass. O f i c . Anal. Chem. 49 13). 536’11966). * ( 3 ) , 536’(1966). (2111) Smith, D. L., Pulliam, A. L., Forist, A. A., J. Pharm. Sci., 55 (4), 398 (1966). (2112) Smith, E., ibid., 56 (5), 630 (1967). (2113) Smith, E., Levine, J., Banes, D., J . Ass. 0 Otfic. . 8 ~Anal. . Chem., 51 ((l), Chem.. l ) ,180 (1968). (2114) Smith, E. L., Pharm.J., 199 (5412), , I

>

I

89 11967’1.

(2115)-Smfth, G., Proc. SOC.Anal. Chem., 4 (2), 18 (1967). (2116) Smith, J. W.G., Grey, G. E. de, Patel, V.J., Analyst (London),92 (1093), 247 (1967). (2117) Smith, L. L., Matthews, IT. S., Price, J . C., Bachmann, R. C., Reynolds, B., J . Chromatogr., 27 i l ) , 187 (1967). (2118) Smith, P. A. S., “Chemistry of Open-Chain Organic Nitrogen Compounds,” Vol. I, Benjamin, New York, S.Y., 1965, 356 pp. (2119) Ibid., Vol. 11, 1966, 531 pp. (2120) Smith, P. J., Hermann, T. S., Anal. Biochem.. 22 (1). 134 11968). (2121) Sm;th, R. C., Kellum, G. E., ANAL. CHEM.,38 (l), 67 (1966). (2122) Smithius, L. 0. 31. J., Pharm. Weekblad, 101 (49), 1097 (1966); Chem. Abstr., 66 79.545~(1967). (2123) Smithius, L. 0 . hI. J., Becker, L. J., ibid., 102 (41), 1049 (1967); Chem. Abstr., 68, 6239k (1968). (2124) Snell, F. C., Snell, C. T., “Colori-

metric Methods of Analysis,” Vol. IVa, Van Nostrand, Princeton, N.J., 1967. (2125) Soczewinski, E . , Matysik, G., Szumilo, H., Separation Sd.,2 (l), 25 (1967). (2126) Socxewinski, E., W o l s k i , T . , Jurkiewicz, K., Ann. Univ. Mariae Curie-Sklodowska, Lublin-Polonia, Sect. A A , 19, 25 (1964 (Pub. 1966); Chem. Abstr., 66, 222679 (1967). (2127) Soibel’man, B. I., Ruzhitskii, D. M., Aptechn. Delo, 15 (3), 62 (1966); Chem. Abstr., 65, 8678a (1966). (2128) Soine, T. O., Lee, K. H., J . Pharm. Sd.,56 ( 5 ) , 655 (1967). (2129) Soldatovic, D., Tomic-Nedeljkovic, AI., Arhiv Farm. (Belgrade), 15 (6), 453 (1965); Chem. Abstr., 66, 821939 (1967). (2130) Solodova, -4.F., Farmatsiya (Moscow), 16 (2), 45 (1967); Chem. Abstr., 67, 14876k (1967). (2131) Solomon-Ionescu, I., Russu, C., Enache, S., Pharm. Zentralh. Deut., 104 (4), 242 (1965); Anal. Abstr., 13, 4411 (1966). (2132) Soltesz, J., Pusxtay, F., Pharmazie, 20 (lo), 656 (1965); Anal. Abstr., 14,990 11967). .. . (2133) Soh, E., Uch. Zap. Tartusk. Gos. Univ., 178, 104 (1955); Chem. Abstr., 67, 84944e (1967). (2134) Somogyi, J., Gyogyszereszet, 10 (3), 100 (1966); Chem. Abstr., 65, 13455c (1966). (2135) Sonanini, D., Anker, L., Pharm. Acta Helv., 42 (l), 54 (1967); Chem. Abstr., 66, 6 8 9 7 9 ~(1967). (2136) Spacu, P., Costin, C., Analele Cniv. Bucuresti, Ser. Stiint. Nut., 13 (I), 19 (1964); Chem. Abstr., 65, 757b (1966). 1213i) SDacu. P.. Iancu-Costin. c.. ibid.. 12 ‘(4f), 63 (1963); Chem. Abstr., 65; 86739 (A966). (2138) Ibzd., p 67; Chem. Abstr., 65, 8674b (1966). (2139) SDahr, J. L., Diss. Abstr., B, 27 (12), 4-269 (1967). 12140) SDahr. J. L.. Knevel. -4.11.. ’ J. Phurm: Sd,55 (lo), 1020 (1966). (2141) Speiser, P., Pharm. Acta Helv., 43 (2), 65 (1968); Chem. Abstr., 68, 62613q ~

~

(1968) ,-~~-,.

(2142) Sperling, A. R., J . Pharm. Sci. 56 ( l ) ,98 (1967). (2143) Spinelli, P., Ciuffi, AI., Boll. Chim. Farm.. 105 (11). 849 (1966): Chem. Abstr.: 66. 68991s’11967) (2144) Spinkova, V., Cesi. Farm., 16 (3), 138 (1967); Chem. Abstr., 67, 4712555 11967) \ - _ _,. . (2145) Spitzer, A., Schweiger, A., Popovici, V., Pharm. Zentralh. Deut., 105 (5), 28i (1966); Anal. Abstr., 14, 5707 (1967). (2146) Splies, R. G., Shellow, J. M.,J . Chem. Eng. Data, 11 (l), 123 (1966). (2147) Springer, V., Benedikovic, I., Chem. Zvesti, 19 (6), 481 (1965); Anal. Abstr., 13, 5530 (1966). (2148) Springer, V., Pikulikova, Z., Farm. Obzor, 34, 418 (1965); Chem. Abstr., 67, 84927b (1967). (2149) Sridharan, K., Ramanujam, S., Sd.Cult. (Calcutta), 32 (8), 416 (1966); Chem. Abstr., 66, 52031t (1967). (2150) Stahl, E., Jork, H., Fresenius’ 2. Anal. Chem., 234 (l), 12 (1968); Chem. Abstr., 68, 53288k (1968). (2151) Stahl, E., Schorn, P. J., Arzneim.Forsch., 17 (lo), 1288 (1967); Chem. Abstr., 68, 431881, (1968). (2152) Stahlavska,-A., Malat, M.,Arzneimittelstandardisierung, 6, 759 (1965); Chem. Abstr., 66, 796571, (1967). (2153) Stanier, C., Anales Real Acad. Farm., 31 ( 5 ) , 273 (1965); Chem. Abstr., 65, 6996h (1966). (2154) Stainier, C., Ann. Pharm. Fr., 24 (3), 221 (1966); Chem. Abstr., 65, 86636 (1966).

(2155) Starichkai, F., Lomakina, N. N., Spiridonova, I. A., Yurina, M. S., Pushkash, XI., Antibiotiki, 12 (2), 126 (1967); Chem. Abstr., 66, 985391 (1967). 12156) Starka., L.., J . Chromatoor., 17 (31, 599 (1965). (2157) Starnes, IT. R., Partlow, T. F., Anal. Biochem., 12 (l),157 (1965). (2158) Steagall, E. F., J . Ass. Ofic. Anal. Chem., 49 (2), 287 (1966). (2159) Steele, J. 117.,Thiessen, J., J . Pharm. Pharmacol., 18 (3), 179 (1966). (2160) Steelink, C., Seikel, 11.K., Downes, F. H., Nature, 206, 614 (1965). (2161) Steen, G. O., Scand. J . Clin. Lab. Invest., 18 (5), 557 (1966). (2162) Steinegger, E., Peters, K., Pharm. Acta Helv., 41 (2), 102 (1966); Anal. Abstr., 14, 3508 (1967). (2163) Sterescu, X., Mihalca, G., Stoicescu, V., Rev. Chim. (Bucharest), 15 (6), 358 (1964); ilnal. Abstr., 12, 5414 (1 / _QA.5) _”_,.

(2164) Stevenson, G. IT.,ANAL.CHEM., 38 (131, 1948 (1966). (2165) Stojic, D., Arhiv. Farm. (Belgrade), 16 (5-6), 417 (1966); Chein. Abstr., 68, 24.5.59~ _ _ _11968). \_ - -. --,-

(2166) Stone, H. I f . , Henwood, C. R., Forensic Sci. SOC.J., 7 (l),51 (1967); Anal. Abstr., 15, 2788 (1968). (2167) Stracciari. G. L., Arch. Ital. Sci. Far’macol. 15 (1-2), 102 (1965): Chem. Abstr.. 66. 22271d 11967). (2168) Stradine, J., Tutane, I. K., Vanags, G., Zh. Anal. Khim., 20 ( l l ) , 1239 (1965); Anal. rlbstr., 14, 4151 (1967). (2169) Straws, D., Rau, I(. H., Deut. Apotheker-Zta., 107 (32), 1107 (1967); Chem. Abstr.; 68, 24586a (1968). 12170) Street. H. V.. J . Chromatoor.. ” , 29 (1),‘68 (1967). (2171) Strickland, R. D., ibid., 24 (2), 455 (1966). (2172) Striegler, G., Gerecke, K., Arzneimittelstandardisieruna. 7. 645 (1966) : Chem. Abstr., 67, 36$75y’(1967). (21731 Strohecker. R.. Deut. BnothekerZ t g : , 106, 1171 (1966); Chem. Abstr., 67, 84903r (1967). (2174) Strzelecka, H., Diss. Pharm., 19 ( l ) , 81 (1967); Anal. Abstr., 15, 2896 ( 1968j . (2175) Stuchlik, XI., Csiba, I., Krasnec, L., Cesk. Farm., 16 (4), 187 (1967); Chem. Abstr., 67, 675302 (1967). (2176) Stuchlik, AI., Krasnec, L., Cesk. Farm., 16 (2), 70 (1967); Chem. Abstr., 67, 25376y (1967). (2177) Stukkei, K. L., Tevs, Fr. G., Stankevich, N. B., Aptechn. Delo, 15 (4),31 (1966); Chem. Abstr., 65, 16792f (1966). (2178) Stulik, K., Zyka, J., Chemist Analyst, 55 (4),120 (1966); Anal. Abstr., 15, 201 (1968). (2179) Suchomelova, L., Horak, V.,Zyka, J., Microchem. J., 9 (2), 196 (1965); Anal. Abstr., 13, 5574 (1966). (2180) Suchy, V., Rada, K., Cesk. Farm., 16 (7), 340 (1967); Chem. Abstr., 67, 120216e (1967). (2181) Sugii, A., Kabasawa, Y., Hasegawa, )I., N i p p o n Daigaku Yakugaku Kenkyu Hokoku, 7, 1 11‘365); Chem. Abstr., 65, 15160f (1966). (2182) Sugita, J., Tsujino, I-., J . Chromatogr., 21 ( 2 ) , 341 (1966). (2183) Suk, V., Smetanova, M.,Cesk. Farm., 14, 158 (1965); Chem. Abstr., 66, 108311d (1967). (2184) Summa, A. F., J . Pharm. Sci., 54 (3), 442 (196.5). (2185) Suprun, P. P., Farm. Zh. (Kiev), 21 (3), 31 (1965); Chem. Abstr., 65, 16792c (1966). (2186) Suszko-Purzycka, A., Poznan. T o w a r z . Przyjaciol. N a u k , Wydzial Lekar., Prace Komisji Farm., 4, 51 (1966); Chem. Abstr., 65, 15156d (1966). ~

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(2187) Suszko-Purzycka, A,, Trzebny, W., ibid., p 43; Chem. Ahstr., 65, 8668e (1966). (268)-Svatek, E.,Cesk. Farm., 14 (6), 332 (1965);Anal. Abstr., 13,5801(1966). (2189) Svatek, E.,Vachek, J., Czechoslovakian patent 115,980 (Sept. 15, 1965); Chem.Abstr., 65,577f (1966). (2190)Svendsen, A. B., Farm. Aikakauslehti, 75 (lo),299 (1966);Chem. Abstr., 66,58859r (1967). (2191) Svendsen, A. B., Veneficus, 29 (4), 84 (1964); Chem. Abstr., 66, 79606w (1967). (2192)Ibid. ( 5 ) , p 107;Chem. Ahstr., 66, 79607~(1967). (2193) Svoboda, J. A., Thompson, 11.J., J . Lipid Res., 8 (2),152 (1967). (2194)Swarbick, J., Rhodes, C. T., J . Pharm. Sci., 54,903 (1965). (2195)Svkora, J., Evbl, V., Pharmazie, 21 (9); 563 11966)”;Chem. Ahstr., 66, 49280t (1967). (2196)Sykulska, Z., Acta Polon. Pharm., 23 (6), 523 (1966);Chem. Ahstr., 66, 108280t (1967). (2197)Sykulska, Z., Kolodziejczyk, Z., -4nn. Acad. M e d . Lodz, 6, 105 (1965); Chem. Abstr., 65,574b (1966). (2198) Szobolcs, E., Acta Pharm. Hung., 36 (51,207 (1966);Chem. Abstr., 65, 1842% 119661.

Ch%. Abstr., 68,”81455j(1968). (2201) Szarras, L., Zurkowska, J., Ozarowrkl, .4., Acta Polon. Pharm., 23 (I), 59 Chem. Abstr., 65,3670b (1966). (1‘366); (2202)Szasi, G., Acta. Pharm. Hung., 35 16),256 (1965):Anal. Abstr., 14,1631 (1967). (2203) Ibid., 36 13), 120 (1966);Chem. dbstr., 65,573h 11966). 12204) Szendey, G. L., Arch. Pharm. (Keinheim), 299 (6),527 fl966); Chem. Sbstr., 65,8671f (1966). (2205)Ibid., 301 (l), 46 (1968);Chem. Abstr., 68,722932 (1968). (2206)Szepeqy, A.,Acta Pharm. Hung., 36 16), 280 (1966);Anal. Abstr., 15, 1013 11968). (2207) Keseru. P.. ibid.. t) * ~~. Szenesv. -1.. 264;C h e k zbstr.’, 66,14015h ’(1967)’. (2208)Szereday, Z., Schneider, H. P.G., Klin. Wochenschr.,43 115),816 (1965); Anal. Abstr., 13,7032 (1966). 12209J Szoke-Szotvori. K.. Elelmiszervizsgalati, Kozleme&., 13 (4), 209 11967): Chpm. Abstr.. 68.62737h 119681. (2210)Szoke-Szotiori, K..Nahrung, 11 (2,,_1_29 (196i), Chem. Abstr., 67,572769 (IYbi).

12211) I b i d . , p 139; Chem. Abstr., 67, 57277h (1967). (2212)Szotyori, K., Elelmiszervizsgalati Kozlemen.. 13 13). 148 11967): Chem. Abstr., 68;33231h’(1968). (2213) Szteiicel-TT’olko~icz,X l . , Wieclawek, B., Kows Anal. (\Tar: 23 (4), $19 (1966); Anal. Abstr., 14,6368 (1967). (2215)I b i d . , 24 (I), 59 (1967); Chem. Abstr., 67,84892 (1967). (2216)Tackie, A. S., Kofi-Tsekpo, IT’. l l . , Hadzija, B. IT.,W . -4jr. Pharm., 9 (21,24, 43 (1967);Chem. rlbstr., 66, 94033~~ (1967). (2217)Takacs, lI., Iiertesz, P., Szabo, B., Vegh, A,, Simonyi, I., Scta Pharm. Hung., 36 (6))241 (1966);Chem. Abstr., 66,22236~11967). (2218)Takahashi, R., Tachi, I., Abhande. Deut. Akad. Wiss. Berlin, KZ. Med., 1966 (4),p 589; Chem. Abstr., 66, 1082932 (1967). 244

R


(2219) Takahashi, S., Ohki, E., Chem. Pharm. Bull. (Tokyo), 15 (ll), 1726 (1967);Chem. Abstr., 68,69284s (1968). (2220) Takahashi, T., Shionogi Kenkyusho Kempo, 15,152 (1965);Chem. Abstr., 67, 471292 (1967). (2221) Tanaka, N., Fijimoto, K., Utsumi, I., Yakugaku Zasshi, 86 (4),282 (1966); Chem. Abstr., 65,2069f (1966). (2222) Tanaka, N.,Hirata, G., Utsumi, I., Chem. Pharm. Bull. (Tokyo), 14 (4), 414 (1966);Chem. Abstr., 65, 5306b (1966). (2223) Tanase, Y.,Shimomura, S., Ito, S., Hino, Y., Tokushima Diagaku Yakugaku Kenkyu Nempo, 13,5(1964);Chem. Abstr.. 65.2068h 11966). (2224)Tarrkrias, H., Bill. SOC.Pharm. Marseille 16 (62), 99 (1967); Chem. Abstr., 67,111386h (1967). (2225)Tatematsu, A., Goto, T., Yakugaku Zasshi. 85 (2).152 (1965):Anal. Abstr.. 13. 5128 11966) (2226)Tatematsu, A.,Xadai, T., Goto, T., Nakajima, Y., Tsuyama, H., Doi, H., Yakzrgaku Zasshi, 87 (4), 329 (1967); Chem. Abstr., 67,67612c (1967). (2227)Tatsuzawa, XI., Eisei Shikenjo Hokoku, 83,5 (1965);Chem. Abstr., 65, 199299 (1966). (2228)I b i d . , p 53;Chem. Abstr., 65,19929h 11966’1. (2229)Tatsuzawa, &I.,Hashiba, S., ibid., p 43; Chem. Abstr., 65,19932c (1966). (2230)Ibid., p 45; Chem. Abstr., 65,19932d (1966). (2231)Taylor, P.IT., Diss. Abstr., 25 (lo), 5875 11965): Univ. hIicrofilms (Ann Arbor. Mich). Order No. 654845.110~~. (222) Teare, F. R., Taylor, D.’ w.,’?. Pharm. Pharmacol., 19 (4), 257 (1967). (2233) Technicon Symposia, Automation in Analvtical Chemistry, Sew York, October- 1966; Pari., November 1966, lfediad, Inc., White Plains, N.Y., 1967, r-01. I,664pp.; F-01.11, 502 pp. (2234) Temple, D. M., Australasian J . Pharm., 47 (559), S62 (1966);Chem. Abstr., 68,6128y (1968). (2235)Tendille, C., Bats, J., Gervais, C., Gaborit, T., Ann. Physiol. Vegetale, 7 12), 85 (1965);Anal. Abstr., 13, 5039 11966). 122361 Teodorescu. G..Dinescu. 8..Bul. Inst. Politph. Bucuresti. 26 (1’1. 49 (1964): Anal. Abstr., 13,5156’(1966j. (2237) Teodorescu, S., Bebesel, E., Farmacia (Bucharest), 14 (12),743 (1966); Chem. Abstr., 67,102843~(1967). (2238)Teodoresdu, K . , Circoana, R . , \-azoiu, V., ibid. (3),p 167:Chem. Abstr.. 65. 12062b 119661. (22341 Teodorescu, N., Coada, M., Zuchi, G., ibid., 15 (8), 485 (1967); Chem. Abstr., 67,111512~(1967). (2240)Teodorescu, N.) Creanga, S., Zuchi, G., ibid (4), p 213; Chem. Abstr., 67, 572839 (1967). (2241)Teodorescu, N .,-_Demetrescu, C., Pharmazie, 22 (lo),si2 (1967);Chem. Abstr., 68,332501,(1968). (2242)Teodorescu, S., Petroniu, L., Ciogolea, G., Farmacia (Bucharest), 15 (l), 13 (1967): Chem. Abstr., 66, 98546t 119671.

(2243)Terada, K.,Ohmura, T., Nippon Sogeikagaku Kaishi, 40 (4),196 (1966); Chem. Abstr., 65,206% (1966). (2244)Tewari, S. N., Mikrochim. Acta, 1967 (4),p 704;Chem. Abstr., 67,67626k (1967). (2245)Thabet, S.K., Tabibian, O., Anal. Chim. Acta, 34 (2),231 (1966). (22461 Thabet. S . II., Vojenske Zdravst. Listy, 36 ( l ) , 12 (1967); Chem. Ahstr., 66, 118875e (1965). (2281) Trkovnik, AI., Ramic, S., GrujicVasic. J.. Glasnak Drustva Hemicara Technol. hR-Bosne Herceaovine. 13-14. 85 (1965) ;Chem.Ahstr., 65,73455C (1966): (2282) Trofimova, N.I., Molchanova, N. G., Kashina, L. V., Shafiev, A. I., Tr. Estestvennonauchn.Inst. Perm. Univ 11 131, 119 (19651: Chem. Ahstr.. 66. 79&4k (1967). (2283) Troughton, ITr.D., Brown, R. S. C., Turner, S. A., Clin. Pathol., 46 ( l ) , 139 (1966); Anal. Ahstr., 14, 6328 (1967). (2284) Trzebinski, J., Wiecko, T., Acta Polon. Pharm. 24 (6) 579 (1967); Chem. Ahstr., 68, 62652h (1968). (2285) Tsarenko, N. Y., Shraiber, AI. S., Farm. Zh. (Kiev), 21 ( 5 ) , 16 (1966); Chem. Ahstr., 66, 49268v (1967). (2256) Tschan, D., Leupin, K., Pharm. Acta Helv., 42 ( l l ) , 657 (1967); Chem. Ahstr., 68, 16176h (1968). (2287) Tsilifonis, D. C., Chafetz, L., J . Pharm. Sci., 56 ( 5 ) , 625 (1967). (2288) Tsuda, T., Ishikawa, I., Sankyo Kenkyusho Nempo, 18, 63 (1966); Chem. Ahstr., 66, 9 8 5 5 8 ~(1967). (2289) Tsuda,T., llizukami, H., Yarimizu, S., zhid., 16, 114 (1964); Chem. Abstr., 65, 151619 (1966). (2290) Tsuda, T., Yamamoto, T., Mizukami. H.. ihid.. 17. 105 119651: , , , Anal. Abst;., 13, 7079 (1966). (2291) Tsuda, T., Yamamoto, T., Yarimizu, S., ihid., 16, 117 (1964); Chem. Ahstr., 65, 15161h (1966). (2292) Tsuda, T., Yarimizu, S., ibid., p 109; Chem. Ahstr., 65, l5161e (1966). (2293) Ihid., p 112; Chem. Ahstr., 65, 1516lj (1966). (2294) Tsuji, A., Bunseki Kagaku, 15 (2), 210 (1966); Chem. Abstr., 65, 10425.f f1966).

(2265j-Tsuji, A., Iiawai, S., Wada, A., Kato, S., Kotaki, M., Eisei Shikenjo Hokoku. 82. 70 (1964): Chem. Abstr., 65. 10426c (1966). (2296) Tsuji, A , , Nakamura, A,, Bunseki Kagaku, 13 ( l l j , 1121 (1964); Anal. Ahstr., 13, 5798 (1966). (2297) Tsuji, A,, Wada, A , , EiseiShzkensho Hokoku, 82, 73 (1964); Chem. Ahstr., 65, 8668h (1966). (2298) T’u, T. Y., Huang, T. T., Lang, C. I., Chieng, C. L., Hua Hsueh Tung Pao, 1966 ( l ) , p 36; Chem. Ahstr., 65, 86699 (1966j. (2299) Tu’ecki, J . , Adamczewska, Z., Poznan. Towarz. Przyjaciol -Vauk, Wydzial Lekar., Prace Komisji Farm., 4 , 83 (1966); Chem. Ahstr., 65, l5157d (1966). (2300) Tuesley, S. P., Sciarra, J. J., RlonteBovi, A. J., J . Pharm. Sci., 57 (3), 488 11968). (2301) Tufegdzic, N., LIirkovic, S., Acta Pharm. Jugoslav., 16, 17 (1966); Chem. Ahstr., 65, 570a (1966). (2302) Tulecki, J., Adamczewska, Z., Diss. Pharm. Pharmacol., 19 ( I ) , 75 (1967); Chem. Ahstr., 67, 543381 (1967). (2303) Tulecki, J., Adamczewska, Z., Poznnn. Tozarz. Przuinciol Yazik. Wudzial Lekar., Prace K%aisji Farm., 2, 91 (1966); Chem. Abslr., 65, l5157e (1966). (2304) Tulus, R., Aydogan, Y., Istanbul Cniv. Eczacilik Fak. Mecm., 3 (2), 105 (1967); Chem. Ahstr., 68, 7227421 (1968). (2305) Tulus,R., Calti, E., ihid., 2 (2), 108 11966): Chem. Ahstr.. 67. 148i9a 11967). (2306) Tulm, S., ihid.; 1 \2), 176 (1965j; Chem. Abstr., 65, 8673s (1966). (2307) Tung, Y. C.‘, Kang, K. T., A-ature, 208, 581 (1965). (2308) Turczan, J. W., J.Ass. Oj%. Anal. Chem.. 50 13). 652 11967). (2309) Turczan,’ J. IT., J . Pharm. Sci., 57 ( l ) , 142 (1968).

(2310) Turczan, J. W.,Kram, T. C., ibid., 56 (12), 1643 (1967). (2311) - -~ Turi, P., Polesuk, J., i t i d . (8), p ~

lull.

(2312) Turner, L. K., J . Forensic Sci., 5 12). 94 11965). (2313) Tutui, K., Sakai, T., Takahashi, XI., Arch. Pract. Pharm., 25 (I), 53 (1965); Anal. Ahstr., 13, 3690 (1966). (2314) T v i c z y n s k a , J., Diss. Pharm. Pharm&d.,-lS ( 5 ) , 491 (1966); Chem. Ahstr., 67, 47110j (1967). 12315) T v f c z v n s k a . J.. Diss. Pharm. Phurmacol., “19 (5); 585 (1967); Chem. Ahstr., 68, 8 9 8 8 9 ~(1968). (2316) Uhlik, B., Munk, RI., Kem. Ind. (Zagreb), 13 ( 5 ) ,336 (1964);Anal. Ahstr., 12, 5409 (1965). (2317) Ulrich, AI., Cesk. Farm., 15 (I), 41 (1966); Anal. Ahstr., 14, 3515 (1967). 12318) Umbreit. G. R.. Houtman. R. L..’ J . bharm. Sck, 56 ( 3 ) , 349 (1967). (2319) Umland, F., Janssen, A., Fortschr. Chem. Forsch., 6 (4), 582-639 (1966); Chem. Abstr., 66, 720489 (1967). (2320) Uno, T., Okuda, H., Yakugaku Zasshi. 86 (121. 1148 (1966): Chem. Abstr.,’66, 58867s (1967). (2321) Uno, T., Sekine, Y., Chem. Pharm. Bull. (Tokyo), 14 (7), 687 (1966); Anal. Ahstr., 14, 6292 (1967). (2322) Uno, T., Yoshida, hl , Yakugaku Zassha. 85 (9). 791 (1965): Chem. Ahstr.. 66, 1082750 (1967). (2323) Unterman, IT. H., Antihiotiki, 10 ( l o ) , 867 (1965); Anal. Ahstr., 14, 983 (1967). (2324) Unterman, W.H., Pharm. Zentralh. Deut., 104 (4), 245 (1965); Anal. Abstr., 13, 4391 (1966). (2325) Crbanyi, T., Rehm, C. R., J . Pharm. Sci., 55 ( 5 ) , 501 (1966). (2326) Urbanyi, T., Sloniewsky, D., Tishler, F., ibid. (7), p 730. (2327) Usmanov, B. Z., Abubakirov, N. K., Khim.-Farm. Zh., 1 (5), 42 (1967); Chem. Ahstr., 67, 84908w (1967). (2328) Uvodic, F. S., Arhiv Farm. (Belgrade), 15 (6), 431 (1965); Chem. Abstr., 67, 2543iu (1967). (2329) Vachek, J., Cesk. Farm., 14 (5), 216 (1965); Anal. Ahstr., 13, 5161 (1966). (2330) Ihid., 15 (9), 506 (1966); Chem. Ahstr., 66, 9856310 (1967). 12331) Vachek, J., Pharmazie, 21 (4), 222 (1966); Chem. Abstr., 65, 53045 (1966). (2332) Vachek, J., Eckschlager, K., Nekvasilova, M.,Cesk. Farm., 15 (5), 260 (1966); Chem. Ahstr., 65, l5161h (1966). (2333) Vachek, J., Kakac, B., Sarsunova, hl., ihid., 16 (5), 229 (1967); Chem. Ahstr., 67, 84907v (1967). (2334) Vadodaria, D. J., Desai, B. R., RIukherji, S. P., Indian J . Pharm., 28 (7), 192 (1966); Chem. Abstr., 65, 167929 (1966) (2335) -i’adodaria, D. J., Vorn, M. N., Mukherji, S. P., ihid., 30 (21, 41 (1968): Chem. Abstr., 68, 72283w (1968). (2336) Vaisberg, E. S., Yakhontova, L. F., Bruna, B. P., Zh. Fiz. Khim., 40 (12), 2953 (1966); Chem. Ahstr., 66, 5 8 8 6 4 ~ (1967). (2337) Vajgand, V. J., Gaal, F. F., Glasnik Hem. DrustvaBeograd,31 (2), 103 (1966); Chem. Ahstr., 68, 432242 (1968). (2338) Vajgand, V. J., Pastor, T. J., ihid. ( l ) ,p 9 ; Chem. Ahstr., 67,39955~(1967). (2339) Vajgand, V. J., Pastor, T. J., G a d , F. F., Todorovic, RI., Proc. Conj. Appl. Phys.-Chem. Methods Chem. A n a l . , Budapest, 1, 152-8 (1966); Chem. Ahstr., 68, 62731b (1968). (2340) Vajgand, V. J., Uvodic, F. S., Glasnik Hem. Drustva, Beograd, 30 (2-3), 89 (1965); Chem. Ahstr., 66, 31988~ 11467) \-I-. ,.

(2341) Ihid. (4-6), p 185; Chem. Ahstr., 66, 1 0 8 2 9 0 ~(1967). (2342) Valerio, R., Ceschel, G. C., Boll.

Chim. Farm.. 105 19). 675 (1966’1:Chem. Abstr., 66, 22273f (1967). (2343) Vamos, J., Brantner, A., Vegh, A., Simonyi, I., Acta Pharm. Hung., 37 (2), 55 (1967): Chem. Ahsir.. 66. 108297d (1967). (2344) Vandenbalck, J. L., J . Pharm. Belg., 20 (11-12), 491 (1965); Chem. Abstr., 65, 573j (1966). (2345) Vanden Heuvel, IT. J. A., Horning, E. C.. Bull. SOC.Chim. Biol.. 47 ( 5 ) .945 (1965); Anal. Ahstr., 14, 330 (1967). (2346) Vanden Heuvel, I T J. A,, Stillwell, R. N., Gardiner, \T’. L., Wikstrom, S. A., Homing, E. C., J . Chromaiogr., 19 ( l ) , 22 (1965). (2347) Vann, L. S., Clan. Chem., 11 ( l l ) , 979 (1965). (2348) Varcel, L., Cesk. Farm., 16 (9), 494 (1967); Chem. Abstr., 68, 81453d (1968). (2349) I-arcl, L., Pharmazae, 23 ( l j , 19 (1968); Chem. Absir., 68, S9908h (1968). (2350) Varga, S , Dillinger, P., Tolgyessy, J., Sarsunova, >I., Proc. Conj. Appl. Phys.-Chem. Nethods Anal., Budapest, 2, 527-36; (1966); Chem. Ahstr., 68, 3 3 2 5 9 ~f1968). (2351) Casileva, B., Tsealyak, I., .4ntihiotiki, 10 ( l o ) , 877 (1965), Anal. Ahstr., 14, 984 il967j. (2352) Vasileva-Alek-aiidrova, P., Alexandrov. A. Mzkrochim. Acta.. 1966 13). p572; Chem. Ahstr., 65, 12061h (1966). ’ (2353 1-asiliev, R., Rev. Chim. (Bucharest), 18 ( 7 ) , 435 11967); Chem. Abstr., 68, 6241e (1968). (2354) Vasiliev, R., Fiuchter, J., Jecu, >I., ihid., 16 (21, 104 (1963); Anal. Ahstr 13, 5 i 9 7 (1966). (2355) qasiliev, R., Jecu, 51.) Fruchter, J.. Farmacza (Bucharest). 15 121. 95 (1967); Chem. Ahstr., 6 6 , l l689jm (1967). (2356) Vaskelis, A,, Gaule, Y. A,, Chausovskii, S. S., Farmatsiya (Moscow), 16 (3), 44 (1967); Chem. Ahstr., 67, 84912t (1967). (2357) Vastagh-Varga, E., Acta Pharm. Hung., 37 ( l ) ,1 (1967);Chem. Ahstr., 66, 108312e (1967). (2358) Vecchi, A, Farmaco, Ed. Prat., 22 (5), 284 (1967); Chem. Ahstr., 68, 16111h (1968). (2359) Ibid. (6)) p 352; Chem. Abstr., 67, 763431 (1967). 12360) Vecchi. 11.. Kaiser. Ii.. ,J. Chromatogr., 26 [l),22 11967j. (2361) T’ecerkova, J., Iiacl, K., Novotna, E., Xikolicova, L., Cesk. Farm., 14 (9), 444 (1965); -4nal. Abstr., 14, 268 (1967). (2362) Vecerkova, J., Kakac, B., Vecerek, B., Kacl, K., Pharmazie, 21 ( l l ) ,676 (1966); Anal. Abstr., 15, 888 (1968). (2363) Vecerkova, J., Kakac, B., I’ecerek, B., Ledvina, ll., ibid., 22 ( l ) ,30 (1967); Chem. Ahstr., 67, 37266d (1967). (2364) Vecerkova, J., Kovotna, E., Cesk. Farm., 14 (9), 462 (1965); Anal. Ahstr., 14, 274 (1967). (2365) Vecerkova, J., Vecerek, B., Iiacl, K., Pharmazie, 21 ( l l ) , 682 (1966); Anal. Ahstr., 15, 888 (1968). (2366) V e c e r k o v a , J . , V e c e r e k , B . , liovotna, E., Cesk. Farm., 15 (9), 491 (1966); Anal. Ahstr., 15, 338 (1968). (2367) Vecsei, P., Lommer, D., Steinaker, H. G., Wolff, H. P., J. Chromatogr., 26 (2), 533 (1967). (2368) Vega, F.A.,Ferniandez, l l , ,llartin, C., Oesterr. Apotheker Ztg., 21 (43), 585 (1967); Chem. Abstr., 68, 627222 (1968). (2369) Vega, F. rl., Fernandez, X, Sunez, C., Ann. Pharm. Fr., 25 ( l ) ,17 (1967); Anal Ahstr., 15, 2900 11968). (2370) Vegh, A , , Szasz, G., Papp, O., Acta Pharm. Hung., 35 (4), 145 (1965), Anal. Ahstr., 13, 6460 (1966). (2371) Veibel, S., “The Identification of Organic Compounds”, 6th ed, Copenhagen, 1966, 468 pp. , /

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-

245 R

(2372) Viederpass, N.,Kirsch, L., Uch. Zap. Tartusk. Gos. Univ., 178,97 (1965); Chem. Abstr., 67, 84941b (1967). (2373) Vengerova, V. Y.,Zzv. Vysshikh Uchebn. Zavedenii, K h i m . i K h i m . Tekhnol., 8 (6),1030 (1965);Anal. Abstr., 14, 4232 (1967). (2374)Venkataraman, A., Modak, M. J., Indian J . Pharm., 27 (12),336 (1965); Anal. Abstr., 14, 2209 (1967). (2375)Ventura, U., Giacalone, E., Sciorelli, G., Znt. 2. Vitaminforsch., 36 (3),286 (1966);Anal. Abstr., 14, 5581 (1967). 123761 Verea. R.. Gnocchi. A.. Boll. Chim. Farm., 165 (4),’332 (1966);Chem. Abstr., 65, 366% (1966). (2377)Vergeichik, E.N.,Bernshtein, V. N., Zvenigorodskii, B. Y., Farmatsiya (hloscow), 16 (2), 41 (1967); Chem. Abstr., 67, 14893~(1967). (2378)Verma, S. C. L., Rao, P. L. N., Indian J . Exp. Biol., 5 (2),106 (1967); Chem. iibstr., 67, 76344~(1967). (2379)Verstraeten, I,. AI. J., 2. Phys. Chem. (Leipzig), 233 (1-2),91 (1966); Chem. Abstr., 68, 38182m (1967). (2380)Vessey, I.,Kendall, C. E., Analyst, 91, 273 (1966). (2381)Vestergaard, P., Raabo, E., J . Gas. Chromatogr., 4 (ll),422 (1966). (2382)Vetter, W.,Vecchi, hl., Gutmann, H., Rueegg, R., Kalther, W., Meyer, P., Helv. Chim. Acta, 50 (7), 1866 (1967); Chem. Abstr., 68, 161812 (1968). (2383) Viala, A, Cano, J. P., Bull. SOC. Pharm. Marseille, 15 (fig),167 (1966); Chem. Abstr., 66, 108281~(1967). (2384)Ibid., p 175; Chem. Abstr., 66, 108282~(1967). 12385)Vickers. C.. J . Pharm. Pharmacol.. S u d d . 18. l? i1966l. (2386)’ Vida,‘ I.,Vastagh, G., Acta Pharm. Hung., 37 (2),67 (1967);Chem. Abstr., 66, 108276~(1967). (2387)1-igneroii, C., Younos, C., Pelt, J. 11..Bull. SOC.Pharm. Nancu. 72. 12 (1967);Chem. Abstr., 67, 11147% (1967). (2388)Vignoli, L., Cristau, B., Defretin, J. Y., Ann. Pharm. Fr., 23 (12),715 (1965);Chem. Abstr., 65, 2063 (1966). (2389)Vignoli, L., Cristau, B., Gouezo, F., Vassalo, J. SI.,Bull. Trav. SOC.Pharm. Lyon, 9 (3), 277 (1965);Chem. Abstr., 65, 167939 (1966). (2390)Vignoli, L., Guillot, J., Gouezo, F., Catalin, J., Ann. Pharm. Fr., 24 (6),461 (1966);Chem. Abstr., 66, 14059~(1967) (2391)Zbid. (7-8).p, 329;Chem. Abstr., 66, 222392 (1967). (2392)Vignoli, L.,Guillot, J., Gouezo, F., Catalin, J., Bull. SOC.Pharm. Marseille, 9 (3),291 (1965);Anal. Abstr., 14, 3502 (1967). (2393)Vilkas, M., Jan, H. I., Boussac, G., Bonnard, A I . C., Tetrahedron Lett., 1966, (14).I) 1441. (2394)Gillela, G. G., hlagalhaes, M.,Rev. Brasil. Biol., 26 (21,127 (1966);Anal. Abstr., 14, 7622 (1967). (2395)Viola, hf. R.,Canestrini, C., Boll. Chim. Farm., 105 (9), 688 (1966);Chem. Abstr., 66, 223532 (1966). (2396)T7iscido,A. A., Martinez, N. R., de, Arch. Bioquim., Quim. Farm., Tucuman, 13, 67 (1966);Chem. Abstr., 68, 53276e (1968). (2397)Viscido, A. A., and Martinez, N. R. de, Arch. Bioquim., Quim. Farm., Trtcuman, 13, 73 (1966);Chem. Abstr., 68, 53279h (1968). (2398)Viehin, A I . L., Gupta, D., Indian J . Pharm., 29 (l),3 (1967);Anal. Abstr., 15. 2239 11968). (2399)Viska, J.,’Cesk. Farm., 16 (3),134 (1967):Chem. Abstr., 68, 81454e (1968). (2400) Viska, J., Okac, A., ibid., 15 (7), 356 (1966);Anal. Abstr., 14,6993(1967). (2401)Ibid., 16 (l), 29 (1967); Chem. Abstr., 66, 108303~(1967). ~

246

R


(2402) Visots’ka, 0.S.,Muchinska, S. K., Shostenko, Y. V., Farm. Zh. (Kiev), 21 (4), 61 (1966);Chem. Abstr., 65, 19929e (1966). (2403)Vitt, S.V., Saporovskaya, M. B., Belikov. V. hl.. Zh. Anal. Khim.. 21 (2),227 (1966): Anal. Abstr., 14, 6327

(2432)Walle, T., Schill, G., Vessman, J., Acta Pharm. Suen’ca, 3 (3),167 (1966); Chem. Abstr., 65, 6997b (1966). (2433) Walter, R. H., Diss. Abstr., B, 28 (l), 228 (1967). (2434) Wang, H. C., Wang, P. Y., Yao Hsueh Hsueh Pao, 13 (l),63 (1966); (1967). Chem. Abstr., 65, 5307b (1966). (2464).Vlasenko, L. M., Aptechn. Delo, 15 (2435) Wang, H. T.,Hsu, L. C., Hua Hsueh Tung Pao, 1966 (3),p 174;Chem. (4),50 (1966);Chem. Abstr., 65, 15153b Abstr., 65, 9735a (1966). (1966). (2405) Vlezenbeek, H. J.,Pharm. Weekblad, (2436)Wang, K.T., Tung, Y. C., Lai, H. H., Nature, 213 (5072),213 (1967). 101 (381.841 (1966): Anal. Abstr.. 14. , (2437) Wang, ?f. C., Chou, T. H., Acta 7822‘(1667). (2406)Vlies, C. van der, Bakker, G. A., Pharm. Sznzca, 12 (ll), 720 (1965); Anal. Abstr., 14, 1648 (1967). Rekker, R. F., ibid. (5), p 93;Anal. (2438) Wanger, O.,Mitt. Gebiete Lebensm. Abstr., 14, 3550 (1967). (2407) Volovel’skii, L. X,, Khukhryanskii, Hyg., 56 (2),87 (1965);Anal. Abstr., 13, 3789 (1966). V. G., Gvirtsman, R. P., Khim.-Farm. (2439) Ranless, J. W.,Australasian J . Zh.. 1 141. 41 (1967):Chem. Abstr.. 67. Pharm., 47 (560),Si3 (1966);Chem. 76346~(1967). Abstr., 67, 67640k (1967). (2408)T’oluiskaya, E. X.,Vopr. Med. (2440) Warolin, C., Ann. Fals. Expert. Khim., 13 (l),91 (1967);Chem. Abstr., Chim., 59, 48 (1966);Anal. Abstr., 14, 66, 79632b (1967). 4983 (1967). (2409)Vos, T.,Kerckhoffs, H . P. hl., (2441) Warren, R. J., Eisdorfer, I. B., Huieinga, T., Pharm. Weekblad, 100 (T), Thompson, K.E., Zarembo, J. E., 228 (1965);Chem. Abstr., 63, 5454h (1 965\. Microchem. J., 12 (4),555 (1967). (2442) Warren, R.J.,Thompson, R. E., (2410)Vroman, H. E.,Cohen, C. F., J . Zarembo, J. E., J . Pharm. Sci., 54 (lo), Lipid Res., 8 (2),150 (1967). 1554 (1965). (2411)Vsiliev, R.,hlangu, M., Burnea, (2443) Warren, R.J., Thompson, W.E., I., Cosmin, A., Rev. CKm. (Bucharest), Zarembo, J. E., Eisdorfer, I. B., ibid., 17 (3),174 (1966);Chem. Abstr., 65, 55 ( 5 ) , 524 (1966). 5303e (1966). (2444) Karrington, H. P., Lennon, J. &I., (2412)Vukcevic-Kovacevic, V.,Vedris, E., ibid., 56 (3),404 (1967). Farm. Glasnik, 23 (7-8), 331 (1967); (2448)Rartman-Hafner, F., Pharm. Acta Chem. Abstr., 68, 24593~(1968). Helu., 41 (i), 406 (1966);Chem. Abstr., (2413) Vulkova, A,, Farmatsiya (Sofia), 65, 1992% (1966). 16 (2), 25 (1966);Chem. Abstr., 65, (2446) TVasickg, R., Akisue, G., Rev. Fac. 15158~(1966). Farm. Bioquim. Uniu. Sao Paulo, 4 (l), (2414)Ibid. (4),p 29; Chem. Abstr., 66, 85 (1966);Chem. Abstr., 67, 1028131 3199% (1967). (1967). (2415) Vulkova, A, Tr. Nauchno-izsled. (2447) Wasilewska, L., Diss. Pharm. Khim. Farm. Znst., 5, 197 (1966);Chem. Pharmacol., 18 (3),305 (1966);Chem. Abstr., 67, 76358b (1967). Abstr., 66, 5805f (1967). (2416)Waaler, T., Kjensli, O., Steinnes, (2448)Watanabe, H., N i p p o n Kagaku E., Medd. Norsk Farm. Selskap, 28 (i), Zasshi, 86, ( 5 ) , 513 (1965);Anal. Abstr., 93 (1966);Chem. Abstr., 66, 14057y 14, 4226 (1967). (1967). (2449) Watanabe, T.,Komada, K., Agr. (2417) Kaarst, V., Arch. Pharm. Chem., Biol. Chem. (Tokyo), 30 (4),418 (1966). 71, 116 (1964);Anal. Abstr., 12, 5301 (2450)Katson, G. R.,Schwartz, B. S., (1965). French patent 1,450,372 (Cl. C 12d) (2418) Ibid., 73 (151, 555 (1966);Chem. (Aug. 19, 1966); U.S. Appl., Feb. 5, Abstr., 65, l5158g (1966). 1965;Chem. Abstr., 66, 588792 (1967). (2419)Wachsmuth, H., Koeckhoven, L. (2451) Keaver, W,J., J . Pharm. Sci., 55 van, J . Pharm. Belg., 19 (46),90 (1964); (lo), 1111 (1966). Chem. dbstr., 66, 140582 (1967). (2452) Weber, J. D., J . Ass. Of. Agr. (2420) Ibid., 20 (1-2),58 (1965);Chem. Chem., 48 (6),1151 (1965). Abstr., 63, 5453c (1965). (2453)Keber, J. D., J . Ass. Ofic. Anal. (2421)Zbid., 22 (749,312 (1967);Chem. Chem., 50 ( 3 ) , 666 (196i). Abstr.. 67. 111472h (1967). (2454) Weber, J. D., Levine, J., J . Pharm. (2422)Ibid.; p 315; Chem. Abstr., 67, Sci., 55 (l),78 (1966). 111503~(1967). (2455) Weeks, C. E., Deutsch, AI. J., J. Ass. Ojic. Agr. Chem., 48 (6),1245 (1965). (2423) Wachtel, H., Abhand. Deut. Akad. (2456)Wegen, T. P.A. van der, Pharm. Wiss. Berlin, Kl. Chem., Geol. Biol., 1966 Weekblad, 103 (lo),245 (1968);Chem. (2), 261-4; Chem. Abstr., 67, 84798k Abstr., 68, 89903~(1968). (1967). (2424)Rachtel, J. L., Peterson, P. K., (2457)Weiss, P.J.,Taliaferro, B., Huckins, R., Chastonay, R., J . Ass. Ofic.Anal. Technicon Symp., 2nd, N.Y. London, Chem., 50 (6), 1294 (1967). 1965, p 3 (Pub. 1966);Chem. Abstr., 67, (2458) Weissbash, S.,Unterman, H . W., 47106% (1967). Studu Cercetari Chim., 14 (ll), 793 (2425)Wagner, G., hlenzel, H., Arznei(1966);Chem. Abstr., 66, 689549 (1967). mittelstandardisierung,7 (4),185 (1966); (2459)Weisz, H., Schepky, G., Zchnoanal. Chem. Abstr., 67, 67664~(1967). Acta, 1965 (4),p 717; Anal. Abstr., 13, (2426) Wagner, G., Nuhn, P., Pharmazie, 4371 (1966). 21, 205 (1966);Chetn. Abstr., 65, 7260f (2460) Welsh, L. H., Samuel, 0. R., J. (1966). Ass. O#c. Anal. Chem.,51 (l),176 (1968). (2427)Wahlig, G., Zentralbl. Bakteriol., (2461) Kestphal, U., Chader, G. J., HardParasitenk., Infektionskr. Hyg., Abt. I., ing, G. B., Steroids, 10 (2),155 (1967). Supple., 2,39(1966)(Pub. 1967); Chem. (2462)Weyers, J., Janik, B., 2. Anal. Abstr., 68, 62720s (1968). Chem.. 218 (4).274 (1966):Chem. Abstr., (2428)Waldi, D., J . Chromatogr., 18 (2), 65, 20669 (1968). 417 (1965). (2463)Weyers, J., Xahl, Z., Acta Polon. (2429)Wallace, J.,Biggs, J., Dahl, E. V., Pharm.. 23 (3).229 11966): , , Chem. Abstr.. ANAL.CHEM.,37 (3),410 (1965). 65, 16795d (1966). 12430) Ibid.. 38 (7).831 (1966). (2464) Wichlinski, L., Skibinski, Z., Farm. Polska, 22 (3),194 (1966);Chem. Abstr., (2431j Wallace, \i.; Anal. Biochem., 20 65, 104259 (1966). (3),411 (1967). I

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(2465) Wichti, M.,Osterr. Apotheker Ztg., 20 (44), 693-7 (1966); Chem. Abstr., 66, 98506e (1967). (2466) TTiFner-Voelkel, M., Juniewicz, J., Rajewski, J., Chem. Anal. (Warsaw), 10 ( 2 ) , 145 (1965);Anal. Abstr., 13, 3842 (1966). (2467)Wijnne, H.J . A, Bletz, E., Frijns, J. hf., Pharm. Weekblad, 102 (38),959 (1967);Chem. Abstr., 67, 102844d (1967). (2468) Wileox, ?\I., J . Pharm. Sci., 56 ( 5 ) , 642 (1967). (2469) Wilczynska, I., Margasinski, Z., Chem.Anal. (Warsaw), 12 ( 5 ) ,991 (1967); Chem. Abstr., 68, 33255u (1968). (2470)Willemot, J.,Parry, G.,Ann. Pharm. Fr., 24 (3),209 (1966);Chem. Abstr., 65, 8670d 119661. (2471) Williams, A. F., ?Jurray, W. J., Gibb, B. H., S a t u r e 211, 816 (1966). (2472)Williams, C. M.,Anal. Biocherr., 11 ( 2 ) , 224 (1965). (2473) Wilson, C. O.,Ed., “Textbook of Organic, SIedicinal and Pharmaceutical Chemistry,” 5th ed., Lippincott, Philadelphia Pa., 1966,9.56pp. (2474)FT’ilson, IT. E.,Johnson, S. A, Perkins, IT. H., Ripley, J. E., ANAL. CHEM.,39 ( l ) ,40 (1967). (2475) \Timer, D.C.. Talanta. 13 110). 1472 (i966j. (2476) Kindheuser, J. J., Chu, D. Y.,J . Pharm. Sci., 56 (4),519 (1967). (2477)Kinkelman, A,, Pharm. Weekblad, 101,833 (1966);Chem. Abstr., 67,93952h (1967). (2478) Kisniewski, IT., Golucki, Z., Acta Palm. Pharm., 23 f3), 235 (1966);Chem. Abstr., 65, 16796d (1966). (2479) Kisniewski, IT., Gorta, T., ibid. 15), p 455; Chem. Abstr., 66, 79619c (1967). (2480) Kisniewski, IY., Kindlik, T., ibid. (6j,p 517: Chem. Abstr., 66, 108317k (1967). (2481) Ibid., 24 (6), 575 (1967);Chem Abstr., 68, 62649j (1968). (2482)JVisniewski, IT., Kindlik, T., Diss. Pharm. Pharmacol., 18 (2),225 (1966); Chem. Abstr., 65, 3673h (1966). (2483) Ibid. (5), p 529; Chem. Abstr., 67, 14908s (1967). (2484)\Tisniewski, IT., KlepaczewskaSaluda, E., Acta Polon. Pharm., 24 (5), 501 (1967);Chen;. Abstr., 68, 432061 (1968). (2485) Risniewski, IT., KlepaczewskaSaluda, E., F a r m . P o ~ s k a ,22 (lo),743 (1966);Ch,em. Abstr., 68, 6275312 (1968). (2486)Wisniewski, W.,Paisecka, H., Acta Polon. Pharm., 24 (3),291 (1967); Chem. Abstr.. 68. 62653~(19681. (2487)il-isniewski, K., ’Piasecka, H., Jablonski, S., Farm. Polska, 23 (3), 211 (19671;Chem. Abstr., 68, 24573~(1968). (2488) Kisniewski, W., Pientura, A,, Acta Polon. Pharm 24 (4), 393 (1967);Chem. Abstr., 68, 16?74z (1968). (2489)Kiiser, IC., Reimaun, IT.,Fritsche, C., Frpseniics’ Z . And. Chem., 230 f3), 189 (1967:; Chem. Absfr., 67, 84904s (1967). (2490) Kohniich, J., Hzdl. SOC.Chzm. Biol., 47 (ll), 2166 (1965);Chern. Abstr., 65, 37h (1966). (2491) Kojsa, K., Rutkowska, E., Kaczmarek, F., Herba Pol. 12 (l), 14 (1966); C h ~ mAbstr., . 65, 16790b (1966). (2492)Xolfrom, 11. L.,Lederkremer, R. 11. de, Schwab, G., J . Chromatogr., 22 121, 474 (1966);Chem. Abstr., 65, 7255 (1966). (2493)Kolfson, B., Ciccarelli, H. E., Giker, E. S., Brit. J . Anaesthesia, 38 ( 8 ) , 591 (1966);Anal Abstr., 14, 7627 (1967,. (2494) Wollmann, C , Nagel, S., Scheibe, E., Pharmazie, 21 (ll), 665 (1966);Anal. Abstr., 15, 1030 (1968). (2495) Xoodson, A. L., J . Ass. OBc. Agr. Chem. 48 (6),1131 (1965). I ,

(2496)Wrightman, K. B.,Barber, R. E., McCadden, R. F., TechniconSymp., 2nd., N.Y. London. 1965. D 12 (Pub. 1966): Chem. Abstr.,’68, 62439 (1968). (2497) Wrightman, IC. B., McCadden, R. F., Ann. N . Y . Acad. Sci., 130 ( 2 ) , 827 (1965). (2498) Kronska-Sofer,T., Sokal, J., Chem. Anal. (Warsaw), 11 (3), 573 11966); Anal. .4bstr., 14, 5613 (1967). (2499) Wronski, 8., ibid. f5), p 957; Anal. Abstr., 15, 375 (1968). (2500) Wronski, AI., ibid. (6),p 1243; Chem. Abstr., 67, 5712b (1967). (2501) Wxensch, A., J . Chromatogr., 30 11). 225 (1967). 12) Rullen. H.. Stainier. E.. J . Pharnz. Bel$., 21 (4-lo), 505 11966); Chem. Abstr., 66, 68972m,(1967). (2503) Ibid., 22 (7-8), 291 (1967);Chem. Abstr., 67, 111473~’(1967). (2504) Kulleri, H., Stainier, E., Luyckx, &I.,ibid., 21 (7-5‘1, 409 (1966);Chem. Abstr., 66, 22265e (196i). (2505) 1-akatan, G. J., Tuckerman, 11. AI., J . Pharm. Sci., 55 (.5), 532 11966). (2506)Yakusheva, Z. P., Tkachuk, E. T., Sb. Stat. Aspirantov Soiskatel., Min. Vyssh. Sred. Spets. Obrazov. KazSSR, Khim. Khim. Tekhnol., 1965, 3-4, pp 89-95; Referat. Zh., Khim. lgGD, 1966 (20),Abstr. No. 200248;Anal. Abstr., 14, 4966 (1967). (2507)Yalcindag, 0.N., Kim. Sanayi, 14 (65-6),47 (1966);Chem. Abstr., 66, 111301j (1967). (2508)Yalcindag, 0. N., Turk, Ijiyen Tecrubi Biyol. Dergisi, Chem. Abstr., 26 kl), 93 11966); Chem. Abstr., 65, 86/89 11966). (2509)Yalcindag, 0.N., Onur, E. E., i b i d . (2), p 163;Chenz. rlbstr., 66,98541n (1967). (2510) Zbid. (3), p 245;Chenz. Abstr., 67, 67672% (1967). (2511)Yamada, M.,Saito, A., Tamura, Z., Chem. Pharm. Bull. (Tokyo), 14 ( 5 ) , 482 (1966);Anal. Abstr., 14,5580 (1967). (2512)Yamamoto, J., Suzuki, Okui, S., Arch. Pract. Pharm 25 (4),265 11965):Anal. Abstr.. 13.’?089 11966). (2513) Zbid., 26 (l), 14’(1966);Anal. Abstr., 13, 7089 (1966). (2514) Yamamoto, J., Suzuki, &I.,Okuo, S., Yakuzaigaku, 25 (4),23 (1965);Chem. Absfr.. 65, 18428d (1966). (2515)Yamamoto, AI., Iguchi, S., Boyama, T., Chem. Pharm. Bull. (Tokyo), 15 il), 123 (1967); Anal. Abstr., 15.2903 (1968). (2516)Yamamoto, Y.,Kumamaru, T., Hayashi, Y., Kobayashi, T., Tanaka, R., ibid. (9),-p 1437;Chem. Abstr., 67, 111501s (1961). (2517) Yamamoto, Y., Kumamaru, T., Tsubouchi, LI., Okiniura, I., B m s e k i Kagakic, 16 (9), 937 11967);Chem. Abstr., 67, 111510~(1967). (2518)Yamana, T., Alizukami, I-., Ynkugaku Zasshi, 87 (ll),1304 (1967);Cheni. Abstr., 68, 5323% (1968). (2519)Yamana, T., llizukami, Y., Tsuji, A . , i h d , (121,p 1447; Chem. dbstr., 68, 89S54f il068). (2520) Yang, I

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