Pharmacokinetics and Metabolism of ... - ACS Publications

plasma, fecal, and metabolized HCB in the rhesus monkey were found to match experimental data ... monkey, respectively, in 40 days (Rozman et al., 197...
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J. Agric. Food Chem., Vol. 26, No. 5, 1978

Yang et al.

Pharmacokinetics and Metabolism of Hexachlorobenzene in the Rat and the Rhesus Monkey Raymond S. H. Yang,*' K. A. Pittman,2 D. R. R ~ u r k eand , ~ V. B. Stein4

The metabolism of hexachlorobenzene (HCB) has been studied with respect to its tissue distribution, disposition, pharmacokinetics, and biotransformation in rats and rhesus monkeys. Preliminary results using the rat for a short-term (48 h) study indicate that a very small portion (